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公开(公告)号:US08809363B2
公开(公告)日:2014-08-19
申请号:US13295167
申请日:2011-11-14
申请人: Andrew Simon Bell , Iain Brian Gardner , Karl Richard Gibson , David Cameron Pryde , Florian Michel Wakenhut
发明人: Andrew Simon Bell , Iain Brian Gardner , Karl Richard Gibson , David Cameron Pryde , Florian Michel Wakenhut
IPC分类号: A61K31/44
CPC分类号: C07D495/04 , A61K31/4365 , A61K31/437 , A61K31/444 , A61K31/506 , A61K45/06 , C07D495/14 , C07D519/00
摘要: The present invention relates to novel 2,3,4-substituted 5,6,7,8-tetrahydro[1]benzothieno[2,3-b]pyridine compounds and pharmaceutically acceptable salts thereof, to compositions containing such compounds and to the use of such compounds as inhibitors of HIV replication.
摘要翻译: 本发明涉及新的2,3,4-取代5,6,7,8-四氢[1]苯并噻吩并[2,3-b]吡啶化合物及其药学上可接受的盐,涉及含有这些化合物的组合物及其用途 的这种化合物作为HIV复制的抑制剂。
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公开(公告)号:US20120136023A1
公开(公告)日:2012-05-31
申请号:US13295167
申请日:2011-11-14
申请人: Andrew Simon Bell , Iain Brian Gardner , Karl Richard Gibson , David Cameron Pryde , Florian Michel Wakenhut
发明人: Andrew Simon Bell , Iain Brian Gardner , Karl Richard Gibson , David Cameron Pryde , Florian Michel Wakenhut
IPC分类号: A61K31/4365 , C07D495/14 , A61P31/18 , C07D495/04
CPC分类号: C07D495/04 , A61K31/4365 , A61K31/437 , A61K31/444 , A61K31/506 , A61K45/06 , C07D495/14 , C07D519/00
摘要: The present invention relates to novel 2,3,4-substituted 5,6,7,8-tetrahydro[1]benzothieno[2,3-b]pyridine compounds and pharmaceutically acceptable salts thereof, to compositions containing such compounds and to the use of such compounds as inhibitors of HIV replication.
摘要翻译: 本发明涉及新的2,3,4-取代5,6,7,8-四氢[1]苯并噻吩并[2,3-b]吡啶化合物及其药学上可接受的盐,涉及含有这些化合物的组合物及其用途 的这种化合物作为HIV复制的抑制剂。
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公开(公告)号:US08575336B2
公开(公告)日:2013-11-05
申请号:US13542153
申请日:2012-07-05
申请人: Jotham Wadsworth Coe , Christoph Martin Dehnhardt , Peter Jones , Steven Wade Kortum , Yogesh Anjil Sabnis , Florian Michel Wakenhut , Gavin Alistair Whitlock
发明人: Jotham Wadsworth Coe , Christoph Martin Dehnhardt , Peter Jones , Steven Wade Kortum , Yogesh Anjil Sabnis , Florian Michel Wakenhut , Gavin Alistair Whitlock
IPC分类号: C07D471/04 , C07D487/04
CPC分类号: C07D471/04 , C07D487/04
摘要: The present invention relates to compounds of formula (I): to pharmaceutically acceptable salts therefore and to pharmaceutically acceptable solvates of said compounds and salts, wherein the substituents are defined herein; to compositions containing such compounds; and to the uses of such compounds in the treatment of various diseases, particularly asthma and COPD.
摘要翻译: 本发明涉及式(I)化合物:因此可药用盐和所述化合物和盐的药学上可接受的溶剂合物,其中取代基在本文中定义; 含有这些化合物的组合物; 以及这些化合物在治疗各种疾病,特别是哮喘和COPD中的用途。
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公开(公告)号:US20130029968A1
公开(公告)日:2013-01-31
申请号:US13542153
申请日:2012-07-05
申请人: Jotham Wadsworth Coe , Christoph Martin Dehnhardt , Peter Jones , Steven Wade Kortum , Yogesh Anil Sabnis , Florian Michel Wakenhut , Gavin Alistair Whitlock
发明人: Jotham Wadsworth Coe , Christoph Martin Dehnhardt , Peter Jones , Steven Wade Kortum , Yogesh Anil Sabnis , Florian Michel Wakenhut , Gavin Alistair Whitlock
IPC分类号: A61K31/437 , A61K31/497 , A61K31/5377 , C07D487/04 , A61K31/55 , A61K31/4375 , A61P27/14 , A61P11/02 , A61P29/00 , A61P11/06 , A61P11/00 , A61P9/12 , A61P17/00 , A61P7/02 , A61P9/10 , A61P19/02 , A61P9/00 , A61P1/16 , A61P19/06 , A61P25/28 , A61P1/00 , A61P25/00 , A61P15/00 , A61P1/04 , A61P9/04 , A61P3/10 , A61P13/12 , A61P27/02 , A61P17/02 , A61P17/06 , A61P3/04 , A61P11/08 , C07D471/04
CPC分类号: C07D471/04 , C07D487/04
摘要: The present invention relates to compounds of formula (I): to pharmaceutically acceptable salts therefore and to pharmaceutically acceptable solvates of said compounds and salts, wherein the substituents are defined herein; to compositions containing such compounds; and to the uses of such compounds in the treatment of various diseases, particularly asthma and COPD.
摘要翻译: 本发明涉及式(I)化合物:因此可药用盐和所述化合物和盐的药学上可接受的溶剂合物,其中取代基在本文中定义; 含有这些化合物的组合物; 以及这些化合物在治疗各种疾病,特别是哮喘和COPD中的用途。
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