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    THERAPEUTIC AGENT FOR GLAUCOMA CONTAINING ADENOSINE DERIVATIVE AS ACTIVE INGREDIENT
    1.
    发明申请
    THERAPEUTIC AGENT FOR GLAUCOMA CONTAINING ADENOSINE DERIVATIVE AS ACTIVE INGREDIENT 审中-公开
    含有腺苷衍生物的GLAUCOMA治疗药物作为主动成分

    公开(公告)号：US20100093770A1

    公开(公告)日：2010-04-15

    申请号：US12450832

    申请日：2008-04-14

    申请人： Atsushi Shimazaki ,  Noriko Kawabata ,  Tomoko Kirihara ,  Jayson M. Rieger ,  Robert D. Thompson

    发明人： Atsushi Shimazaki ,  Noriko Kawabata ,  Tomoko Kirihara ,  Jayson M. Rieger ,  Robert D. Thompson

    IPC分类号： A61K31/52 ,  A61P27/06

    CPC分类号： A61K31/7076 ,  C07H19/167

    摘要： A method for treating glaucoma or ocular hypertension comprising administering to a patient a pharmacologically effective amount of a compound represented by the following (1) or a salt thereof: wherein X represents CH or N; R1 represents a hydrogen atom, a hydroxy group, a halogen atom, an alkyl group, an alkoxy group, a cycloalkyl group, a cycloalkoxy group, a (cycloalkyl)methoxy group, or  R2 represents a hydrogen atom, an alkyl group, a cycloalkyl group, an alkylcarbonyl group or an alkyloxycarbonyl group; and Ra and Rb are the same or different and represent a hydrogen atom, a hydroxy group, a halogen atom, an alkyl group, an alkoxy group, a cycloalkyl group or a cycloalkoxy group.

    摘要翻译： 一种治疗青光眼或高眼压症的方法，其特征在于，向患者施用药理学有效量的下述（1）表示的化合物或其盐：其中，X表示CH或N; R1表示氢原子，羟基，卤素原子，烷基，烷氧基，环烷基，环烷氧基，（环烷基）甲氧基，或R2表示氢原子，烷基，环烷基 基团，烷基羰基或烷氧基羰基; R a和R b相同或不同，表示氢原子，羟基，卤素原子，烷基，烷氧基，环烷基或环烷氧基。