公开(公告)号：US07767827B2

公开(公告)日：2010-08-03

申请号：US11915016

申请日：2006-05-22

申请人： Atsushi Uchida ,  Wakako Yokota ,  Kenji Hirai ,  Tomoyuki Yano

发明人： Atsushi Uchida ,  Wakako Yokota ,  Kenji Hirai ,  Tomoyuki Yano

IPC分类号： C07D231/10

CPC分类号： C07D231/20

摘要： Disclosed are pyrazole-1-carboxylate derivatives of the general formula (1), (wherein symbols are as defined in the specification), a process for the production thereof and processes for producing herbicidally active 3-aryloxypyrazole-1-carboxamide derivatives from the above compound and an intermediate therefor. According to this invention, there can be industrially advantageously produced 3-aryloxypyrazole-1-carboxamide derivatives that does not cause chemical damage on crops but exhibits excellent herbicidal activity against weeds that impair the growth of such crops.

摘要翻译： 公开了通式（1）的吡唑-1-羧酸酯衍生物（其中符号如说明书中所定义），其制备方法和从上述产生除草活性3-芳氧基吡唑-1-甲酰胺衍生物的方法 化合物及其中间体。 根据本发明，可以在工业上有利地生产不对作物造成化学损害的3-芳氧基吡唑-1-甲酰胺衍生物，但是对于损害这些作物生长的杂草显示出优异的除草活性。

公开(公告)号：US20090018345A1

公开(公告)日：2009-01-15

申请号：US11915016

申请日：2006-05-22

申请人： Atsushi Uchida ,  Wakako Yokota ,  Kenji Hirai ,  Tomoyuki Yano

发明人： Atsushi Uchida ,  Wakako Yokota ,  Kenji Hirai ,  Tomoyuki Yano

IPC分类号： C07D231/20

CPC分类号： C07D231/20

摘要： Disclosed are pyrazole-1-carboxylate derivatives of the general formula (1), (wherein symbols are as defined in the specification), a process for the production thereof and processes for producing herbicidally active 3-aryloxypyrazole-1-carboxamide derivatives from the above compound and an intermediate therefor. According to this invention, there can be industrially advantageously produced 3-aryloxypyrazole-1-carboxamide derivatives that does not cause chemical damage on crops but exhibits excellent herbicidal activity against weeds that impair the growth of such crops.

摘要翻译： 公开了通式（1）的吡唑-1-羧酸酯衍生物（其中符号如说明书中所定义），其制备方法和从上述产生除草活性3-芳氧基吡唑-1-甲酰胺衍生物的方法 化合物及其中间体。 根据本发明，可以在工业上有利地生产不对作物造成化学损害的3-芳氧基吡唑-1-甲酰胺衍生物，但是对于损害这些作物生长的杂草显示出优异的除草活性。

公开(公告)号：US07863460B2

公开(公告)日：2011-01-04

申请号：US11884665

申请日：2006-02-23

申请人： Hidenori Aihara ,  Wakako Yokota ,  Tetsu Yamakawa ,  Kenji Hirai

发明人： Hidenori Aihara ,  Wakako Yokota ,  Tetsu Yamakawa ,  Kenji Hirai

IPC分类号： C07D231/14

CPC分类号： C07D231/14

摘要： In a process for producing 1-substituted-3-fluoroalkyl-pyrazole-4-carboxylate (3) by a reaction of 2-alkoxymethylenefluoroacylacetate (1) and hydrazine (2), the reaction is conducted in the presence of a base and water, to produce 1-substituted-3-fluoroalkylpyrazole-4-carboxylate (3) with high selectivity and yield. This novel process enables to produce 1-substituted-3-fluoroalkylpyrazole-4-carboxylate (3), which is useful as an intermediate for pharmaceuticals and agrochemicals, with high selectivity and yield by simple and safe operations.

摘要翻译： 在通过2-烷氧基甲基三氟酰基乙酸酯（1）和肼（2）的反应制备1-取代-3-氟烷基 - 吡唑-4-羧酸酯（3）的方法中，反应在碱和水的存在下进行， 以高选择性和产率制备1-取代-3-氟烷基吡唑-4-羧酸酯（3）。 该新方法能够通过简单和安全的操作产生具有高选择性和产率的1-取代-3-氟烷基吡唑-4-羧酸酯（3），其可用作药物和农用化学品的中间体。

公开(公告)号：US20080154045A1

公开(公告)日：2008-06-26

申请号：US11884665

申请日：2006-02-23

申请人： Hidenori Aihara ,  Wakako Yokota ,  Tetsu Yamakawa ,  Kenji Hirai

发明人： Hidenori Aihara ,  Wakako Yokota ,  Tetsu Yamakawa ,  Kenji Hirai

IPC分类号： C07D231/14

CPC分类号： C07D231/14

摘要： In a process for producing 1-substituted-3-fluoroalkyl-pyrazole-4-carboxylate (3) by a reaction of 2-alkoxymethylenefluoroacylacetate (1) and hydrazine (2), the reaction is conducted in the presence of a base and water, to produce 1-substituted-3-fluoroalkylpyrazole-4-carboxylate (3) with high selectivity and yield. This novel process enables to produce 1-substituted-3-fluoroalkylpyrazole-4-carboxylate (3), which is useful as an intermediate for pharmaceuticals and agrochemicals, with high selectivity and yield by simple and safe operations.

摘要翻译： 在通过2-烷氧基甲基三氟酰基乙酸酯（1）和肼（2）的反应制备1-取代-3-氟烷基 - 吡唑-4-羧酸酯（3）的方法中，反应在碱和水的存在下进行， 以高选择性和产率制备1-取代-3-氟烷基吡唑-4-羧酸酯（3）。 该新方法能够通过简单和安全的操作产生具有高选择性和产率的1-取代-3-氟烷基吡唑-4-羧酸酯（3），其可用作药物和农用化学品的中间体。