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33 条记录 (耗时 0.023 秒)

    Process for preparing pyrrolidine
    5.
    发明授权
    Process for preparing pyrrolidine 有权
    制备吡咯烷的方法

    公开(公告)号：US09315479B2

    公开(公告)日：2016-04-19

    申请号：US13940964

    申请日：2013-07-12

    申请人： BASF SE

    发明人： Roland Bou Chedid ,  Johann-Peter Melder ,  Roman Dostalek ,  Jörg Pastre ,  Aik Meam Tan

    IPC分类号： C07D295/027

    CPC分类号： C07D295/027

    摘要： Process for preparing pyrrolidine of the formula I by reacting 1,4-butanediol (BDO) of the formula II with ammonia in the presence of hydrogen and a supported, metal-containing catalyst, wherein the catalytically active mass of the catalyst, prior to its reduction with hydrogen, comprises oxygen-containing compounds of aluminum, copper, nickel and cobalt and in the range from 0.2 to 5.0% by weight of oxygen-containing compounds of tin, calculated as SnO, and the reaction is carried out in the liquid phase at an absolute pressure in the range from 160 to 220 bar, a temperature in the range from 160 to 230° C., using ammonia in a molar ratio to BDO used of from 5 to 50 and in the presence of 1.0 to 4.5% by weight of hydrogen, based on the amount of BDO used.

    摘要翻译： 通过使式II的1,4-丁二醇（BDO）与氨在负载的含金属催化剂的存在下与氨反应制备式I的吡咯烷的方法，其中催化剂的催化活性物质在其 用氢还原，包括铝，铜，镍和钴的含氧化合物，并且在0.2至5.0重量％的锡的含氧化合物的锡的范围内，以SnO计算，并且反应在液相中进行 在160-240巴范围内的绝对压力下，温度在160-230℃的范围内，使用与BDO的摩尔比为5至50的氨和在1.0至4.5％的存在下，通过 基于所用BDO的量，氢的重量。

    Process for Preparing Piperazine
    7.
    发明申请
    Process for Preparing Piperazine 有权
    哌嗪制备方法

    公开(公告)号：US20130331573A1

    公开(公告)日：2013-12-12

    申请号：US13910554

    申请日：2013-06-05

    申请人： BASF SE

    发明人： Roland Bou Chedid ,  Johann-Peter Melder ,  Ulrich Abel ,  Roman Dostalek ,  Nina Challand ,  Bernd Stein ,  Michael Jödecke

    IPC分类号： C07D241/04 ,  C07C213/04 ,  C07C209/28

    CPC分类号： C07D241/04 ,  C07C209/28 ,  C07C213/04 ,  C07D295/023 ,  C07D295/027

    摘要： Process for preparing piperazine of the formula I by reacting diethanolamine (DEOA) of the formula II with ammonia in the presence of hydrogen and a supported, metal-containing catalyst has been found, wherein the catalytically active mass of the catalyst, prior to its reduction with hydrogen, comprises oxygen-containing compounds of aluminum, copper, nickel and cobalt and in the range from 0.2 to 5.0% by weight of oxygen-containing compounds of tin, calculated as SnO, and the reaction is carried out in the liquid phase at an absolute pressure in the range from 160 to 220 bar, a temperature in the range from 180 to 220° C., using ammonia in a molar ratio to DEOA used of from 5 to 25 and in the presence of 0.2 to 9.0% by weight of hydrogen, based on the total amount of DEOA used and ammonia.

    摘要翻译： 已经发现通过使式II的二乙醇胺（DEOA）与氢气和负载的含金属的催化剂的氨反应制备式I的哌嗪的方法，其中催化剂的催化活性物质在其还原之前 与氢气一起包含铝，铜，镍和钴的含氧化合物，其含量为0.2至5.0重量％，以SnO计算的含氧化合物锡，反应在液相中进行 使用160-220巴的绝对压力，温度在180-220℃范围内，使用摩尔比为DEA的氨为5至25，在0.2至9.0重量％存在下 的氢气，基于使用的DEOA的总量和氨。

    Method for producing amino acids
    9.
    发明授权
    Method for producing amino acids 有权
    生产氨基酸的方法

    公开(公告)号：US09428443B2

    公开(公告)日：2016-08-30

    申请号：US14893661

    申请日：2014-05-14

    申请人： BASF SE

    发明人： Christian Gruenanger ,  Roland Bou Chedid ,  Markus Christian Biel ,  Johann-Peter Melder

    IPC分类号： C07C227/00 ,  C07C227/08

    CPC分类号： C07C227/08 ,  C07C229/24 ,  C07C229/22 ,  C07C229/08

    摘要： Process for the preparation of alkali metal salts of glycine or of racemic α-amino acids of the general formula (I) R1—CH(NH2)—COOH  (I) in which R1 is selected from hydrogen, CH3, C2H5, CH(CH3)2, (CH2)2COOH and CH2OH, wherein an alkali metal salt of the corresponding α-ketocarboxylic acid or glyoxalic acid is reacted in the presence of at least one heterogeneous catalyst, which comprises at least one transition metal, in the presence of hydrogen with at least one nitrogen compound at temperatures in the range from 50 to 200° C., where the nitrogen compound is selected from primary and secondary amines and ammonia.

    摘要翻译： 制备甘氨酸碱金属盐或通式（I）R 1 -CH（NH 2）-COOH（I）的外消旋α-氨基酸的方法，其中R 1选自氢，CH 3，C 2 H 5，CH（CH 3） ）2，（CH 2）2 COOH和CH 2 OH，其中相应的α-酮羧酸或乙醛酸的碱金属盐在至少一种包含至少一种过渡金属的非均相催化剂存在下，在氢气存在下反应 与至少一种氮化合物在50至200℃的温度范围内，其中氮化合物选自伯胺和仲胺和氨。

    Process for the preparation of a mono-N-alkylpiperazine
    10.
    发明授权
    Process for the preparation of a mono-N-alkylpiperazine 有权
    制备单-N-烷基哌嗪的方法

    公开(公告)号：US08927712B2

    公开(公告)日：2015-01-06

    申请号：US13906931

    申请日：2013-05-31

    申请人： BASF SE

    发明人： Roland Bou Chedid ,  Johann-Peter Melder ,  Ulrich Abel ,  Roman Dostalek ,  Bernd Stein

    IPC分类号： C07D241/04 ,  C07D295/00 ,  C07D295/088 ,  B01J23/83 ,  B01J35/02 ,  B01J37/00 ,  B01J37/03 ,  C07D295/03 ,  B01J37/08 ,  B01J37/18

    CPC分类号： C07D295/088 ,  B01J23/83 ,  B01J35/023 ,  B01J37/0009 ,  B01J37/031 ,  B01J37/08 ,  B01J37/18 ,  B01J2523/00 ,  C07D295/03 ,  B01J2523/17 ,  B01J2523/31 ,  B01J2523/3706

    摘要： Process for the preparation of a mono-N-alkylpiperazine of the formula I in which R1 is C1- to C5-alkyl or 2-(2-hydroxyethoxy)ethyl, by reacting diethanolamine (DEOA) of the formula II with a primary amine of the formula H2N—R1 (III) in the presence of hydrogen and a catalyst molding, where the reaction is carried out in the liquid phase at an absolute pressure in the range from 150 to 250 bar and the amination is carried out by means of a catalyst molding, the precursor of which can be prepared according to a process in which (i) an oxidic material comprising copper oxide, aluminum oxide and lanthanum oxide is provided, (ii) pulverulent metallic copper and/or copper flakes and optionally graphite is added to the oxidic material, (iii) the mixture resulting from step ii is shaped to give a molding, where the oxidic material is obtainable by simultaneous or successive precipitation of the component copper oxide, of the component aluminum oxide and of the component lanthanum oxide and subsequent drying and calcination and, after the shaping according to step iii, the catalyst molding is calcined again.

    摘要翻译： 通过使式II的二乙醇胺（DEOA）与式Ⅰ的伯胺反应制备其中R 1为C 1 -C 5 - 烷基或2-（2-羟基乙氧基）乙基的式I的单-N-烷基哌嗪的方法 在氢气和催化剂模塑的存在下，式H2N-R1（III），其中反应在150-250巴的绝对压力下在液相中进行，并且胺化通过 催化剂成型，其前体可以根据其中（i）包含氧化铜，氧化铝和氧化镧的氧化物质的方法制备，（ii）加入粉末状金属铜和/或铜片以及任选的石墨 （iii）由步骤ii得到的混合物成型为得到模制品，其中氧化物质可通过组分氧化铜，组分氧化铝和组分氧化镧同时或连续沉淀获得，以及 随后的干燥和煅烧，并且根据步骤iii的成型后，再次煅烧催化剂成型。