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公开(公告)号:US09957256B2
公开(公告)日:2018-05-01
申请号:US15313343
申请日:2015-05-26
发明人: Sergii Pazenok , Norbert Lui , Christian Funke
IPC分类号: C07D403/04 , C07D231/16 , C07D231/14 , C07C21/18 , C07D401/14 , C07D231/38
CPC分类号: C07D403/04 , C07C21/18 , C07D231/14 , C07D231/16 , C07D231/38 , C07D401/14
摘要: A new process for the preparation of 5-fluoro-1H-pyrazoles of the general formula (I) as described herein and further reactions with this compound.
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公开(公告)号:US10189800B2
公开(公告)日:2019-01-29
申请号:US15763181
申请日:2016-09-23
发明人: Christian Funke , Arnd Neeff , Sergii Pazenok , Norbert Lui
IPC分类号: C07D271/113
摘要: A method for preparing N-(1,3,4-oxadiazol-2-yl)arylcarboxamides of formula (I) is described. The substituents therein are radicals such as hydrogen, alkyl, haloalkyl or aryl.
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公开(公告)号:US09765033B2
公开(公告)日:2017-09-19
申请号:US14892280
申请日:2014-05-19
发明人: Sergii Pazenok , Norbert Lui
IPC分类号: C07D231/12 , C07D231/14 , C07C251/80 , C07C251/88
CPC分类号: C07D231/12 , C07C251/80 , C07C251/88 , C07D231/14
摘要: The present invention describes a novel method for preparing 3,5-bis(fluoroalkyl)pyrazole derivatives.
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公开(公告)号:US09725415B2
公开(公告)日:2017-08-08
申请号:US15037564
申请日:2014-11-25
发明人: Sergii Pazenok , Norbert Lui , Christian Funke , Arnd Neeff , Vadim Mikhailovich Timoshenko , Elena Ivanovna Kaminskaya , Yuriy Grigorievich Shermolovich
IPC分类号: C07D231/16 , C07D403/04 , C07D231/14 , C07D231/38
CPC分类号: C07D231/16 , C07D231/14 , C07D231/38 , C07D403/04
摘要: A new process for the preparation of 5-fluoro-1H-pyrazoles of the general formula (I) as described herein, resulting from the reaction of an olefin with hydrazine in the presence of water and a base.
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公开(公告)号:US09656966B2
公开(公告)日:2017-05-23
申请号:US15113377
申请日:2015-01-22
发明人: Norbert Lui , Sergii Pazenok
IPC分类号: C07D231/16
CPC分类号: C07D231/16
摘要: The present invention relates to a novel method for preparing 1-alkyl-3-difluoromethyl-5-fluor-1H-pyrazole-4-carbaldehydes or esters thereof of formula (I) by means of reductive dehalogenation, starting from 1-alkyl-3-chlorodifluoromethyl-5-fluoro-1H-pyrazole-4-carbaldehydes or esters thereof Formula (I)
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公开(公告)号:US09951023B2
公开(公告)日:2018-04-24
申请号:US15022901
申请日:2014-09-04
发明人: Norbert Lui , Sergii Pazenok
IPC分类号: C07D231/16 , C07D231/14
CPC分类号: C07D231/16 , C07D231/14
摘要: A method for the preparation of compounds of formula (I), for example, N-methyl-3-difluoromethyl-5-fluorpyrazole aldehyde, starting from compounds of formula (II), for example, N-methyl-3-haloalkyl-5 chloropyrazole aldehyde, comprising simultaneous fluorination (one step process) of haloalkyl group in position 3 and replacing haloatom in position 5 by fluorine.
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公开(公告)号:US09701640B2
公开(公告)日:2017-07-11
申请号:US15127908
申请日:2015-03-20
发明人: Sergii Pazenok , Norbert Lui , Christian Funke , Winfried Etzel , Arnd Neeff
IPC分类号: C07D231/12 , C07C251/08 , C07F5/02 , C07D231/14
CPC分类号: C07D231/12 , C07C251/08 , C07D231/14 , C07F5/022
摘要: The present invention relates to a novel process for preparing 3,5-bis(haloalkyl)pyrazole derivatives from α,α-dihaloamines and ketimines.
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公开(公告)号:US09856222B2
公开(公告)日:2018-01-02
申请号:US15317921
申请日:2015-06-08
发明人: Sergii Pazenok , Norbert Lui
IPC分类号: C07D231/12
CPC分类号: C07D231/12 , C07D231/14
摘要: Process for preparing 3,5-bis(haloalkyl)pyrazole derivatives of the formula (I), via acylation of Hydrazones.
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公开(公告)号:US09914704B2
公开(公告)日:2018-03-13
申请号:US15317927
申请日:2015-06-08
发明人: Sergii Pazenok , Norbert Lui
IPC分类号: C07D231/12 , A01N43/56
CPC分类号: C07D231/12 , A01N43/56 , C07D231/14
摘要: The present invention relates to a novel process for preparing 3,5-bis(haloalkyl)pyrazole derivatives of the formula (Ia) and (Ib), via acylation of ketimines.
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公开(公告)号:US09845312B2
公开(公告)日:2017-12-19
申请号:US15037402
申请日:2014-11-25
发明人: Sergii Pazenok , Norbert Lui
IPC分类号: C07D403/04 , C07D231/14 , C07D231/16
CPC分类号: C07D403/04 , C07D231/14 , C07D231/16
摘要: A new process for the preparation of 5-fluoro-1H-pyrazoles of the general formula (I) as described herein comprising reacting an olefin with an hydrazine.
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