公开(公告)号：US20170252464A1

公开(公告)日：2017-09-07

申请号：US15500024

申请日：2015-07-22

Applicant: BRACCO IMAGING S.P.A. ,  UNIVERSITA DI PAVIA

Inventor： Elena ELISEI ,  Attilio CESARO ,  Marta FILIBIAN ,  Pietro CARRETTA ,  Sonia COLOMBO SERRA ,  Alessandro MAIOCCHI ,  Fabio TEDOLDI

IPC: A61K49/10 ,  A61K49/18

CPC classification number: A61K49/10 ,  A61K49/18

Abstract: A method for preparing a sample for dynamic nuclear polarization which comprises submitting a solid substrate to a milling process in the presence of a polarizing agent at a temperature lower than the glass-transition temperature (Tg) of said substrate. Preferably said substrate may be in crystalline form.