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1.
公开(公告)号:US20070224607A1
公开(公告)日:2007-09-27
申请号:US11584880
申请日:2006-10-23
申请人: Barry Morgan , Stephen Hale , Christopher Arico-Muendel , Matthew Clark , Richard Wagner , David Israel , Malcolm Gefter , Dennis Benjamin , Nils Hansen , Malcolm Kavarana , Steffen Creaser , George Franklin , Paolo Centrella , Raksha Acharya
发明人: Barry Morgan , Stephen Hale , Christopher Arico-Muendel , Matthew Clark , Richard Wagner , David Israel , Malcolm Gefter , Dennis Benjamin , Nils Hansen , Malcolm Kavarana , Steffen Creaser , George Franklin , Paolo Centrella , Raksha Acharya
CPC分类号: C12N15/1068 , C07H21/00
摘要: The present invention provides a method for identifying a compound of interest by screening libraries of molecules which include an encoding oligonucleotide tag.
摘要翻译: 本发明提供了通过筛选包括编码寡核苷酸标签的分子文库来鉴定感兴趣的化合物的方法。
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公开(公告)号:US20070042401A1
公开(公告)日:2007-02-22
申请号:US11450938
申请日:2006-06-09
申请人: Barry Morgan , Stephen Hale , Christopher Arico-Muendel , Matthew Clark , Richard Wagner , David Israel , Malcolm Gefter , Dennis Benjamin , Nils Hansen , Malcolm Kavarana , Steffen Creaser , George Franklin , Paolo Centrella , Raksha Acharya
发明人: Barry Morgan , Stephen Hale , Christopher Arico-Muendel , Matthew Clark , Richard Wagner , David Israel , Malcolm Gefter , Dennis Benjamin , Nils Hansen , Malcolm Kavarana , Steffen Creaser , George Franklin , Paolo Centrella , Raksha Acharya
CPC分类号: C12N15/1068 , C07H21/00 , C40B50/10
摘要: The present invention provides a method of synthesizing libraries of molecules which include an encoding oligonucleotide tag.
摘要翻译: 本发明提供合成包含编码寡核苷酸标签的分子文库的方法。
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公开(公告)号:US20050158765A1
公开(公告)日:2005-07-21
申请号:US11015458
申请日:2004-12-17
申请人: Barry Morgan , Stephen Hale , Christopher Arico-Muendel , Matthew Clark , Richard Wagner , David Israel , Malcolm Gefter , Dennis Benjamin , Nils Hansen , Malcolm Kavarana , Steffen Creaser , George Franklin , Paolo Centrella , Raksha Acharya
发明人: Barry Morgan , Stephen Hale , Christopher Arico-Muendel , Matthew Clark , Richard Wagner , David Israel , Malcolm Gefter , Dennis Benjamin , Nils Hansen , Malcolm Kavarana , Steffen Creaser , George Franklin , Paolo Centrella , Raksha Acharya
CPC分类号: C07H21/00 , C12N15/1068 , C40B50/10
摘要: The present invention provides a method of synthesizing libraries of molecules which include an encoding oligonucleotide tag.
摘要翻译: 本发明提供合成包含编码寡核苷酸标签的分子文库的方法。
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4.Methods and compositions for modulating sphingosine -1- phosphate (S1P) receptor activity 审中-公开
标题翻译: 调节鞘氨醇-1-磷酸(S1P)受体活性的方法和组合物公开(公告)号:US20080064662A1
公开(公告)日:2008-03-13
申请号:US11805020
申请日:2007-05-22
申请人: Ashis Saha , Malcolm Kavarana , Ghotas Evindar , Alexander Satz , Barry Morgan
发明人: Ashis Saha , Malcolm Kavarana , Ghotas Evindar , Alexander Satz , Barry Morgan
IPC分类号: A61K31/12 , A61K31/165 , A61K31/36 , A61K31/38 , A61K31/403 , A61K31/415 , A61K31/4164 , A61K31/425 , A61K31/44 , A61K31/661 , A61K31/665 , C07C233/07 , C07D209/82 , C07D213/00 , C07D231/10 , C07D233/00 , C07D233/54 , C07D277/20 , C07D333/06 , C07D493/00 , C07F9/09 , C07F9/6571
CPC分类号: C07D213/30 , C07C237/04 , C07C237/06 , C07C237/08 , C07C237/16 , C07C237/42 , C07C317/40 , C07C323/41 , C07C2601/14 , C07D207/12 , C07D209/82 , C07D209/88 , C07D231/10 , C07D231/12 , C07D233/54 , C07D233/64 , C07D277/20 , C07D277/28 , C07D317/58 , C07D317/64 , C07D333/06 , C07D333/16 , C07D417/10 , C07D493/04 , C07F9/091 , C07F9/3808 , C07F9/5728 , C07F9/65031 , C07F9/6506 , C07F9/6539 , C07F9/65517 , C07F9/655345 , C07F9/65586 , C07F9/65742
摘要: The present invention relates to compounds which modulate the activity of the S1P1 receptor, the use of these compounds for treating conditions associated with signaling through the S1P1 receptor, and pharmaceutical compositions comprising these compounds.
摘要翻译: 本发明涉及调节S1P1受体活性的化合物,这些化合物用于治疗与通过S1P1受体的信号传导相关的病症的用途,以及包含这些化合物的药物组合物。
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5.Methods and compositions for modulating sphingosine-1-phosphate (S1P) receptor activity 失效
标题翻译: 调节鞘氨醇-1-磷酸(S1P)受体活性的方法和组合物公开(公告)号:US20060135786A1
公开(公告)日:2006-06-22
申请号:US11204266
申请日:2005-08-12
申请人: Ashis Saha , Malcolm Kavarana , Ghotas Evindar , Alexander Satz , Barry Morgan
发明人: Ashis Saha , Malcolm Kavarana , Ghotas Evindar , Alexander Satz , Barry Morgan
IPC分类号: C07D233/54 , C07F9/22
CPC分类号: C07D213/30 , C07C237/04 , C07C237/06 , C07C237/08 , C07C237/16 , C07C237/42 , C07C317/40 , C07C323/41 , C07C2601/14 , C07D207/12 , C07D209/82 , C07D209/88 , C07D231/10 , C07D231/12 , C07D233/54 , C07D233/64 , C07D277/20 , C07D277/28 , C07D317/58 , C07D317/64 , C07D333/06 , C07D333/16 , C07D417/10 , C07D493/04 , C07F9/091 , C07F9/3808 , C07F9/5728 , C07F9/65031 , C07F9/6506 , C07F9/6539 , C07F9/65517 , C07F9/655345 , C07F9/65586 , C07F9/65742
摘要: The present invention relates to compounds which modulate the activity of the S1P1 receptor, the use of these compounds for treating conditions associated with signaling through the S1P1 receptor, and pharmaceutical compositions comprising these compounds.
摘要翻译: 本发明涉及调节S1P1受体活性的化合物,这些化合物用于治疗与通过S1P1受体的信号传导相关的病症的用途,以及包含这些化合物的药物组合物。
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