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    Nucleotide sequences which code for the zwa1 gene
    1.
    发明授权
    Nucleotide sequences which code for the zwa1 gene 失效
    编码zwa1基因的核苷酸序列

    公开(公告)号：US06632644B2

    公开(公告)日：2003-10-14

    申请号：US09731909

    申请日：2000-12-08

    申请人： Bettina Möckel ,  Walter Pfefferle ,  Achim Marx ,  Jörn Kalinowski ,  Brigitte Bathe ,  Alfred Pühler

    发明人： Bettina Möckel ,  Walter Pfefferle ,  Achim Marx ,  Jörn Kalinowski ,  Brigitte Bathe ,  Alfred Pühler

    IPC分类号： C12P1308

    CPC分类号： C07K14/34 ,  C12N9/00 ,  C12P13/08

    摘要： The invention relates to an isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70% to a polynucleotide which codes for a polypeptide which comprises the amino acid sequence of SEQ ID NO 2, b) polynucleotide which codes for a polypeptide which comprises an amino acid sequence which is identical to the extent of at least 70% to the amino acid sequence of SEQ ID NO 2 c) polynucleotide which is complementary to the polynucleotides of a) and b) and d) polynucleotide comprising at least 15 successive nucleotides of the polynucleotide sequence of a), b) or c), and processes for the fermentative preparation of L-amino acid with amplification of the zwa1 gene in the coryneform bacteria employed.

    摘要翻译： 本发明涉及一种分离的多核苷酸，其包含选自以下的多核苷酸序列：a）与编码多肽的多核苷酸的程度相同的多核苷酸，所述多核苷酸包含氨基酸序列 b）编码多肽的多核苷酸，其包含与SEQ ID NO 2的氨基酸序列至少70％的程度相同的氨基酸序列，c） 与a）和b）和d）多核苷酸互补的多核苷酸，其包含a），b）或c），/或PTEXT的多核苷酸序列的至少15个连续核苷酸的多核苷酸，以及发酵 在使用棒状细菌中扩增zwa1基因的L-氨基酸的制备

    Polynucleotide sequences which encode the zwa1 gene
    2.
    发明授权
    Polynucleotide sequences which encode the zwa1 gene 失效
    编码zwa1基因的多核苷酸序列

    公开(公告)号：US07074607B2

    公开(公告)日：2006-07-11

    申请号：US10640263

    申请日：2003-08-14

    申请人： Bettina Möckel ,  Walter Pfefferle ,  Achim Marx ,  Jörn Kalinowski ,  Brigitte Bathe ,  Alfred Pühler

    发明人： Bettina Möckel ,  Walter Pfefferle ,  Achim Marx ,  Jörn Kalinowski ,  Brigitte Bathe ,  Alfred Pühler

    IPC分类号： C12P1/00 ,  C12N1/20 ,  C12N15/00 ,  C07K1/00 ,  C07H21/02

    CPC分类号： C07K14/34 ,  C12N9/00 ,  C12P13/08

    摘要： The invention relates to an isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70% to a polynucleotide which codes for a polypeptide which comprises the amino acid sequence of SEQ ID NO 2, b) polynucleotide which codes for a polypeptide which comprises an amino acid sequence which is identical to the extent of at least 70% to the amino acid sequence of SEQ ID NO 2 c) polynucleotide which is complementary to the polynucleotides of a) and b) and d) polynucleotide comprising at least 15 successive nucleotides of the polynucleotide sequence of a), b) or c), and processes for the fermentative preparation of L-amino acid with amplification of the zwa1 gene in the coryneform bacteria employed.

    摘要翻译： 本发明涉及一种分离的多核苷酸，其包含多核苷酸序列，所述多核苷酸序列选自a）多核苷酸，其与编码包含SEQ ID NO：2的氨基酸序列的多肽的至少70％的多核苷酸程度相同 b）编码多肽的多核苷酸，其包含与SEQ ID NO：2的氨基酸序列至少70％的程度相同的氨基酸序列）与a）和b的多核苷酸互补的多核苷酸 ）和d）包含a），b）或c）的多核苷酸序列的至少15个连续核苷酸的多核苷酸，以及在所用棒状细菌中扩增zwa1基因的L-氨基酸的发酵制剂的方法。

    Nucleotide sequences encoding the sucC and sucD genes
    5.
    发明授权
    Nucleotide sequences encoding the sucC and sucD genes 失效
    编码sucC和sucD基因的核苷酸序列

    公开(公告)号：US06623946B1

    公开(公告)日：2003-09-23

    申请号：US09728498

    申请日：2000-11-27

    申请人： Bettina Möckel ,  Walter Pfefferle ,  Achim Marx

    发明人： Bettina Möckel ,  Walter Pfefferle ,  Achim Marx

    IPC分类号： C12N916

    CPC分类号： C12N9/93 ,  C12P13/04 ,  C12P13/14

    摘要： Polynucleotides that contain polynucleotide sequences encoding the sucC and sucD genes, selected from the group a) a polynucleotide that is at least 70% identical to a polynucleotide encoding a polypeptide that contains the amino acid sequence of SEQ ID NO:2, b) a polynucleotide that is at least 70% identical to a polynucleotide encoding a polypeptide that contains the amino acid sequence of SEQ ID NO:3, c) a polynucleotide encoding a polypeptide that contains an amino acid sequence that is at least 70% identical to the amino acid sequence of SEQ ID NO:2, d) a polynucleotide encoding a polypeptide that contains an amino acid sequence that is at least 70% identical to the amino acid sequence of SEQ ID NO:3, e) a polynucleotide that is complementary to one of the polynucleotides of a), b), c) or d), and f) a polynucleotide containing at least 15 successive nucleotides of the polynucleotide sequence of a), b), c), d) or e), a process for the fermentative production of L-amino acids using coryneform bacteria in which the genes are present in attenuated form, and the use of the polynucleotide sequences as hybridization probes.

    摘要翻译： 含有编码sucC和sucD基因的多核苷酸序列的多核苷酸，选自组a）与编码含有SEQ ID NO：2的氨基酸序列的多肽的多核苷酸至少70％同一性的多核苷酸，b）多核苷酸 与编码含有SEQ ID NO：3的氨基酸序列的多肽的多核苷酸至少70％相同，c）编码包含与氨基酸序列至少70％相同的氨基酸序列的多肽的多核苷酸 SEQ ID NO：2的d氨基酸序列，d）编码含有与SEQ ID NO：3的氨基酸序列至少70％相同的氨基酸序列的多肽的多核苷酸，e）与 a），b），c）或d）的多核苷酸，和f）包含a），b），c），d）或e）的多核苷酸序列的至少15个连续核苷酸的多核苷酸，发酵生产的方法 的L-氨基酸 其中基因以减毒形式存在的干细胞，以及多核苷酸序列用作杂交探针。

    Nucleotide sequences coding for the genes sucC and sucD
    7.
    发明授权
    Nucleotide sequences coding for the genes sucC and sucD 失效
    编码基因sucC和sucD的核苷酸序列

    公开(公告)号：US06897055B2

    公开(公告)日：2005-05-24

    申请号：US09838564

    申请日：2001-04-20

    申请人： Bettina Möckel ,  Walter Pfefferle ,  Achim Marx

    发明人： Bettina Möckel ,  Walter Pfefferle ,  Achim Marx

    IPC分类号： C12N9/00 ,  C12P13/04 ,  C12P13/14 ,  C12N9/12

    CPC分类号： C12N9/93 ,  C12P13/04 ,  C12P13/14

    摘要： The invention relates to polynucleotides that contain polynucleotide sequences coding for the genes sucC and sucD, selected from the group a) polynucleotide that is at least 70% identical to a polynucleotide coding for a polypeptide that contains the amino acid sequence of SEQ ID No. 2, b) polynucleotide that is at least 70% identical to a polynucleotide coding for a polypeptide that contains the amino acid sequence of SEQ ID No. 3, c) polynucleotide coding for a polypeptide that contains an amino acid sequence that is at least 70% identical to the amino acid sequence of SEQ ID No. 2, d) polynucleotide coding for a polypeptide that contains an amino acid sequence that is at least 70% identical to the amino acid sequence of SEQ ID No. 3, e) polynucleotide that is complementary to the polynucleotides of a), b), c) or d), and f) polynucleotide containing at least 15 successive nucleotides of the polynucleotide sequence of a), b), c), d) or e), a process for the fermentative production of L-amino acids using coryneform bacteria in which the genes are present in attenuated form, and the use of the polynucleotide sequences as hybridization probes.

    摘要翻译： 本发明涉及含有编码基因sucC和sucD的多核苷酸序列的多核苷酸，其选自a）与编码含有SEQ ID No.2的氨基酸序列的多肽的多核苷酸至少70％相同的多核苷酸 ，b）与编码含有SEQ ID No.3的氨基酸序列的多肽的多核苷酸至少70％相同的多核苷酸，c）编码含有至少70％的氨基酸序列的多肽的多核苷酸， 与SEQ ID No.2的氨基酸序列相同，d）编码含有与SEQ ID No.3的氨基酸序列至少70％相同的氨基酸序列的多肽的多核苷酸，e） 与a），b），c）或d）的多核苷酸互补，以及f）包含a），b），c），d）或e）的多核苷酸序列的至少15个连续核苷酸的多核苷酸， 发酵生产 使用棒状细菌的L-氨基酸，其中基因以减毒形式存在，以及使用多核苷酸序列作为杂交探针。