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公开(公告)号:US20050070490A1
公开(公告)日:2005-03-31
申请号:US10609150
申请日:2003-06-25
申请人: Birgit Jaitner , Wendy Fantl
发明人: Birgit Jaitner , Wendy Fantl
IPC分类号: C07K14/47 , C12N15/113 , A61K48/00 , A61K39/395 , C07H21/02
CPC分类号: C12N15/1136 , C07K14/4705
摘要: Inhibitors of human Sos1, including antisense oligonucleotides, methods, and compositions specific for human Sos1, are provided. Methods of using the compositions for modulating Sos1 expression and for regulating cell growth, particularly tumor cell growth, are also provided.
摘要翻译: 提供人Sos1的抑制剂,包括反义寡核苷酸,方法和人Sos1特异性的组合物。 还提供了使用该组合物调节Sos1表达和调节细胞生长,特别是肿瘤细胞生长的方法。