Oxadiazole derivatives and their medical use
    1.
    发明授权
    Oxadiazole derivatives and their medical use 有权
    恶二唑衍生物及其医疗用途

    公开(公告)号:US08017631B2

    公开(公告)日:2011-09-13

    申请号:US11919146

    申请日:2006-04-24

    IPC分类号: A61K31/4245 C07D413/04

    摘要: This invention relates to novel oxadiazole derivatives, which are found to be modulators of the nicotinic acetylcholine receptors. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.

    摘要翻译: 本发明涉及新的恶二唑衍生物,其被发现是烟碱乙酰胆碱受体的调节剂。 由于其药理学特征,本发明的化合物可用于治疗与中枢神经系统(CNS),周围神经系统(PNS),疾病或病症相关的胆碱能系统相关的疾病或障碍 平滑肌肉收缩,内分泌疾病或病症,与神经变性相关的疾病或病症,与由化学物质的滥用终止引起的炎症,疼痛和戒断症状相关的疾病或病症。

    Novel oxadiazole derivatives and their medical use
    2.
    发明申请
    Novel oxadiazole derivatives and their medical use 有权
    新型恶二唑衍生物及其医疗用途

    公开(公告)号:US20090312347A1

    公开(公告)日:2009-12-17

    申请号:US11919146

    申请日:2006-04-24

    摘要: This invention relates to novel oxadiazole derivatives, which are found to be modulators of the nicotinic acetylcholine receptors. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.

    摘要翻译: 本发明涉及新的恶二唑衍生物,其被发现是烟碱乙酰胆碱受体的调节剂。 由于其药理学特征,本发明的化合物可用于治疗与中枢神经系统(CNS),周围神经系统(PNS),疾病或病症相关的胆碱能系统相关的疾病或障碍 平滑肌肉收缩,内分泌疾病或病症,与神经变性相关的疾病或病症,与由化学物质的滥用终止引起的炎症,疼痛和戒断症状相关的疾病或病症。