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19 条记录 (耗时 0.033 秒)

    Biosensing meter with ambient temperature estimation method and system
    1.
    发明授权
    Biosensing meter with ambient temperature estimation method and system 失效
    具有环境温度估计方法和系统的生物传感仪

    公开(公告)号：US5405511A

    公开(公告)日：1995-04-11

    申请号：US073179

    申请日：1993-06-08

    申请人： Bradley E. White ,  Michael L. Brown ,  Paul G. Ritchie ,  Vladimir Svetnik ,  Robert A. Parks ,  Stefan Weinert

    发明人： Bradley E. White ,  Michael L. Brown ,  Paul G. Ritchie ,  Vladimir Svetnik ,  Robert A. Parks ,  Stefan Weinert

    IPC分类号： G01N27/26 ,  G01N27/327 ,  G01N27/416 ,  G01N33/487

    CPC分类号： G01N27/3274 ,  G01K7/42

    摘要： A biosensing meter is provided that determines a value of an analyte in a biological sample. The meter employs an algorithm for determining the analyte value, which value is dependent upon ambient temperature about the biological sample when it is present in a reaction zone. The biosensing meter includes a processor and a temperature sensor. The temperature sensor is positioned within the meter's structure and thereby exhibits a delayed response to changes in the ambient temperature. The meter performs a temperature estimation method to overcome the delayed temperature response. The method commences by the meter repetitively and periodically acquiring temperature readings from the temperature sensor when the biosensing meter is both in an on state and in an off state. When the meter is in the on state, the algorithm estimates the ambient temperature by employing at least two most recent temperature readings and extrapolating therefrom to achieve an ambient temperature estimate. Temperature readings are acquired by the meter at first intervals when the meter is in the off state and at second, shorter intervals when the meter is in the on state, the temperature extrapolations only occurring when the meter is in the on state.

    摘要翻译： 提供了生物传感计，其确定生物样品中分析物的值。 仪表采用一种用于确定分析物值的算法，该值取决于生物样品当存在于反应区域时的环境温度。 生物传感计包括处理器和温度传感器。 温度传感器位于仪表结构内，从而对环境温度的变化表现出延迟的响应。 仪表执行温度估计方法以克服延迟温度响应。 当生物传感仪处于打开状态并处于关闭状态时，该仪器重复开始并周期性地从温度传感器获取温度读数。 当仪表处于打开状态时，该算法通过采用至少两个最近的温度读数来估计环境温度，并从中推断出来以实现环境温度估计。 当仪表处于关闭状态时，仪表以第一时间间隔获取温度读数，当仪表处于打开状态时以秒为单位，温度外推仅在仪表处于打开状态时发生。

    Biosensing meter with fail/safe procedures to prevent erroneous indications
    2.
    发明授权
    Biosensing meter with fail/safe procedures to prevent erroneous indications 失效
    生物传感仪具有故障/安全程序，以防止错误的指示

    公开(公告)号：US5352351A

    公开(公告)日：1994-10-04

    申请号：US73180

    申请日：1993-06-08

    申请人： Bradley E. White ,  Robert A. Parks ,  Paul G. Ritchie ,  Vladimir Svetnik

    发明人： Bradley E. White ,  Robert A. Parks ,  Paul G. Ritchie ,  Vladimir Svetnik

    IPC分类号： G01N27/26 ,  G01N27/327 ,  G01N27/416 ,  G01N33/487

    CPC分类号： G01N27/3273

    摘要： A biosensing meter receives a sample strip that includes electrically isolated sense and excitation electrodes bridged by a reaction zone. When a drop of biological sample fluid is placed in the reaction zone, a plurality of fail/safe tests are performed. A drop size test is performed by a circuit that detects the size of the drop placed in the reaction zone. The circuit both detects that a drop has been placed in the reaction zone and further measures a test current level, after a delay, to determine that the drop size is sufficient to enable hydration of reactants in the reaction zone. Subsequently, during the reaction, a "delta" current change is measured at succeeding sample time. This test measures the difference between succeeding current samples during a measurement time. If each succeeding sample is not less than preceding sample by a delta value, a determination is made that the current is not monotonically decreasing and the test is aborted. At the termination of the measurement time, a current sum test is performed wherein a processor calculates a linear sum of all sample test currents and calculates a ratio between that sum and the last current sample. If that ratio matches a pre-calculated constant for the Cottrell relationship, then it is known that the measurement values exhibit the Cottrell relationship.

    摘要翻译： 生物传感仪接收包含由反应区桥接的电隔离的感应和激发电极的样品条。 当将一滴生物样品流体置于反应区域中时，进行多次故障/安全试验。 通过检测放置在反应区中的液滴尺寸的电路进行液滴尺寸测试。 电路两者都检测到液滴已经放置在反应区域中，并且在延迟之后进一步测量测试电流水平，以确定液滴尺寸足以使反应物质在反应区域中水合。 随后，在反应期间，在随后的采样时间测量“delta”电流变化。 该测试测量测量时间中后续电流样本之间的差异。 如果每个后续样本不小于先前样本的Δ值，则确定电流不是单调递减，并且测试中止。 在测量时间结束时，执行电流和测试，其中处理器计算所有采样测试电流的线性和，并且计算该和与最后一个当前采样之间的比率。 如果该比率匹配Cottrell关系的预先计算的常数，则已知测量值表现出Cottrell关系。

    Devices and methods relating to electrochemical biosensors
    10.
    发明申请
    Devices and methods relating to electrochemical biosensors 有权
    与电化学生物传感器有关的设备和方法

    公开(公告)号：US20050023152A1

    公开(公告)日：2005-02-03

    申请号：US10872008

    申请日：2004-06-18

    申请人： Nigel Surridge ,  Paul Walling ,  Melani Sullivan ,  Vladimir Svetnik ,  Brian Hill

    发明人： Nigel Surridge ,  Paul Walling ,  Melani Sullivan ,  Vladimir Svetnik ,  Brian Hill

    IPC分类号： B01L3/02 ,  C12Q1/00 ,  G01N1/00 ,  G01N27/00 ,  G01N27/30 ,  G01N33/487

    CPC分类号： C12M1/00 ,  C12Q1/001 ,  G01N27/3272

    摘要： A system for testing for analytes in a sample of biological fluid includes a test strip that defines a cavity for receiving the sample. At least two sets of electrodes are adjacent the sample cavity, including one for measuring one property of the sample, and another for measuring one or more other properties of the sample, such as temperature and/or the presence or magnitude of confounding variables. The measurements are combined to yield the desired result. At least one set of working and counter electrodes each have a plurality of elongated “fingers” interdigitated with those of the other electrode in the set. The gaps between fingers can be quite small, so that the two electrode sets together can operate in a small measurement volume of sample. Additional electrodes can be included that measure the presence or sufficiency of the sample, and additional traces on the strip can act as configuration identifiers.

    摘要翻译： 用于测试生物流体样品中分析物的系统包括限定用于接收样品的空腔的测试条。 至少两组电极与样品腔相邻，包括一个用于测量样品的一个性质，另一组用于测量样品的一个或多个其他性质，如温度和/或混杂变量的存在或大小。 将测量结合以产生期望的结果。 至少一组工作电极和对电极各自具有与组中的另一电极的那些相互指向的多个细长的“指状物”。 手指之间的间隙可能相当小，使得两个电极组合可以在小的测量体积的样品中操作。 可以包括测量样品的存在或充分性的附加电极，并且条带上的附加痕迹可以用作配置标识符。