利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

32 条记录 (耗时 0.025 秒)

    Cement mixing and dispensing device
    3.
    发明授权
    Cement mixing and dispensing device 失效
    水泥搅拌和分配装置

    公开(公告)号：US06592251B2

    公开(公告)日：2003-07-15

    申请号：US09771317

    申请日：2001-01-26

    申请人： Brian Edwards ,  Paul Higham ,  Joseph Zitelli

    发明人： Brian Edwards ,  Paul Higham ,  Joseph Zitelli

    IPC分类号： B01F506

    CPC分类号： B01F11/0082 ,  A61B17/8825 ,  A61C5/62 ,  A61C5/68 ,  A61J1/2055 ,  A61J1/2096 ,  A61M5/31596 ,  B01F5/0685 ,  B01F5/0688 ,  B01F13/002 ,  B01F15/0225 ,  B01F2215/0029

    摘要： An apparatus and method for mixing a liquid component and a powdered component to form a bone filler has first and second syringes each having a barrel, a plunger and an exit port. The plunger is moveable with the barrel of each syringe along a longitudinal axis of the barrel. An end portion of each plunger extends beyond the end of each barrel when the plunger tip is spaced from the exit port and can be activated to move the plunger tip toward the exit port. A mechanism for mixing the liquid and powdered components is operatively connected to each of the barrels and plungers of the first and second syringes so that the relative sliding movement of first and second parts of the mechanism simultaneously moves the plungers and barrels of the first and second syringes relative to one another to move the combined liquid and powdered components back and forth between the first and second syringe.

    摘要翻译： 用于混合液体组分和粉末组分以形成骨填料的装置和方法具有每个具有筒，柱塞和出口的第一和第二注射器。 柱塞可以沿着每个注射器的枪管沿着镜筒的纵向轴线移动。 当柱塞尖端与出口间隔开时，每个柱塞的端部延伸超过每个筒的端部，并且可以被启动以使柱塞尖端朝向出口移动。 用于混合液体和粉末组分的机构可操作地连接到第一和第二注射器的每个桶和柱塞，使得机构的第一和第二部分的相对滑动运动同时移动第一和第二注射器的柱塞和桶 注射器相对于彼此在第一和第二注射器之间来回移动组合的液体和粉末组分。

    Apparatus for mixing a liquid and dry powdered components
    4.
    发明授权
    Apparatus for mixing a liquid and dry powdered components 失效
    用于混合液体和干燥粉末组分的装置

    公开(公告)号：US06494611B2

    公开(公告)日：2002-12-17

    申请号：US09770982

    申请日：2001-01-26

    申请人： Brian Edwards ,  Paul Higham ,  Joseph Zitelli

    发明人： Brian Edwards ,  Paul Higham ,  Joseph Zitelli

    IPC分类号： B01F1100

    CPC分类号： B01F11/0014 ,  A61B2017/8838 ,  A61C5/68 ,  B01F3/12 ,  B01F11/0008 ,  B01F2215/0029

    摘要： An apparatus for mixing dry and liquid components is used to form a setting paste. A holder is mounted on the apparatus for reciprocating movement with respect to a base of the apparatus. The movement has an amplitude with components in first and second perpendicular directions. A drive system is operatively connected to the holder for imparting said reciprocating movement to said holder at a predetermined number of cycles per minute. A container having a mass of said dry and liquid components therein is mounted in the holder. The mass, amplitude and cycles per minute of reciprocation being chosen to produce an energy input of at least about 3×10−3 Joules per second per 3 cc of mixture.

    摘要翻译： 用于混合干燥和液体组分的装置用于形成凝固糊。 保持器安装在设备上，用于相对于设备的基座往复运动。 运动具有在第一和第二垂直方向上的分量的振幅。 驱动系统可操作地连接到保持器，用于以每分钟预定数量的周期将所述往复运动传递到所述保持器。 其中具有所述干燥和液体成分的质量的容器安装在保持器中。 选择往复运动的每分钟的质量，振幅和循环以产生每3cc混合物至少约3×10 -3焦耳/秒的能量输入。

    Antibiotic calcium phosphate coating
    5.
    发明申请
    Antibiotic calcium phosphate coating 审中-公开
    抗生素磷酸钙涂层

    公开(公告)号：US20050169964A1

    公开(公告)日：2005-08-04

    申请号：US11059864

    申请日：2005-02-17

    申请人： Joseph Zitelli ,  Paul Higham ,  Paresh Dalal ,  Christopher Scott

    发明人： Joseph Zitelli ,  Paul Higham ,  Paresh Dalal ,  Christopher Scott

    IPC分类号： A61L27/32 ,  A61L27/54 ,  A61L2/00 ,  A61K9/14

    CPC分类号： A61L27/54 ,  A61L27/32 ,  A61L2300/252 ,  A61L2300/406 ,  A61L2300/414 ,  A61L2300/606

    摘要： A process for applying a coating having a therapeutic agent such as an antibiotic or a bone morphogenic protein such as OP-1 protein to an implant uses the high surface area of a calcium phosphate coated metal implant as a repository for the therapeutic agent. The implant is coated with one or more layers of calcium phosphate minerals such as hydroxyapatite. After the crystalline layer is applied, which is usually done within an aqueous solution, the implant is dried and packaged. Immediately prior to implantation, the implant is removed from the package and the crystalline layer of calcium phosphate is wetted with an aqueous solution containing the therapeutic agent.

    摘要翻译： 将具有治疗剂如抗生素或骨形态发生蛋白如OP-1蛋白的涂层施用于植入物的方法使用磷酸钙涂覆的金属植入物的高表面积作为治疗剂的储存库。 植入物涂覆有一层或多层磷酸钙矿物质，如羟基磷灰石。 在通常在水溶液中进行结晶层之后，将植入物干燥并包装。 在植入之前，立即从包装中取出植入物，并用含有治疗剂的水溶液润湿磷酸钙的结晶层。

    Antibiotic calcium phosphate coating
    6.
    发明授权
    Antibiotic calcium phosphate coating 失效
    抗生素磷酸钙涂层

    公开(公告)号：US06821528B2

    公开(公告)日：2004-11-23

    申请号：US10610730

    申请日：2003-07-01

    申请人： Christopher Scott ,  Joseph Zitelli ,  Paul Higham

    发明人： Christopher Scott ,  Joseph Zitelli ,  Paul Higham

    IPC分类号： B05D100

    CPC分类号： A61L27/54 ,  A61L27/32 ,  A61L2300/406 ,  A61L2300/606

    摘要： A process for applying a coating having a therapeutic agent such as an antibiotic or a bone morphogenic protein to an implant uses the high surface area of a calcium phosphate coated metal implant as a repository for the therapeutic agent. The implant is coated with one or more layers of calcium phosphate minerals such as hydroxyapatite. After the crystalline layer is applied, which is usually done within an aqueous solution, the implant is dried and packaged. Immediately prior to implantation, the implant is removed from the package and the crystalline layer of calcium phosphate is wetted with an aqueous solution containing the therapeutic agent.

    摘要翻译： 将具有治疗剂如抗生素或骨形态发生蛋白的涂层施用于植入物的方法使用磷酸钙涂覆的金属植入物的高表面积作为治疗剂的储存库。 植入物涂覆有一层或多层磷酸钙矿物质，如羟基磷灰石。 在通常在水溶液中进行结晶层之后，将植入物干燥并包装。 在植入之前，立即从包装中取出植入物，并用含有治疗剂的水溶液润湿磷酸钙的结晶层。

    Antibiotic calcium phosphate coating
    7.
    发明授权
    Antibiotic calcium phosphate coating 失效

    公开(公告)号：US06596338B2

    公开(公告)日：2003-07-22

    申请号：US10001525

    申请日：2001-10-24

    申请人： Christopher Scott ,  Joseph Zitelli ,  Paul Higham

    发明人： Christopher Scott ,  Joseph Zitelli ,  Paul Higham

    IPC分类号： B05D100

    CPC分类号： A61L27/54 ,  A61L27/32 ,  A61L2300/406 ,  A61L2300/606

    摘要： A process for applying a coating having a therapeutic agent such as an antibiotic to an implant uses the high surface area of a calcium phosphate coated metal implant as a repository for the therapeutic agent. The implant is coated with one or more layers of calcium phosphate minerals such as hydroxyapatite. After the crystalline layer is applied, which is usually done within an aqueous solution, the implant is dried and packaged. Immediately prior to implantation, the implant is removed from the package and the crystalline layer of calcium phosphate is wetted with an aqueous solution containing the therapeutic agent.

    Data-driven pattern detection of implantable medical device data
    8.
    发明授权
    Data-driven pattern detection of implantable medical device data 有权
    可植入医疗器械数据的数据驱动模式检测

    公开(公告)号：US08265753B2

    公开(公告)日：2012-09-11

    申请号：US12884021

    申请日：2010-09-16

    申请人： Paul Higham ,  Atila Amiri

    发明人： Paul Higham ,  Atila Amiri

    IPC分类号： A61N1/362

    CPC分类号： A61B5/1118 ,  A61B5/0424 ,  A61B5/0809 ,  A61B5/1459 ,  A61B5/4809 ,  A61B2562/0219 ,  A61N1/372 ,  G06K9/0053

    摘要： Detecting patterns in sensed implantable medical device (IMD) data is described. One implementation involves an IMD that includes a data-driven pattern detection network embodied on the IMD to detect a pattern from sensed patient data. The IMD also includes one or more algorithms embodied on the IMD to utilize the pattern to effect patient therapy.

    摘要翻译： 描述了感测的可植入医疗装置（IMD）数据中的检测模式。 一个实现涉及IMD，其包括体现在IMD上的数据驱动模式检测网络，以检测来自感测的患者数据的模式。 IMD还包括在IMD上体现的一种或多种算法来利用该模式来影响患者治疗。