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8 条记录 (耗时 0.015 秒)

    Methods and compositions for the rapid and enduring relief of inadequate myocardial function
    2.
    发明授权
    Methods and compositions for the rapid and enduring relief of inadequate myocardial function 失效

    公开(公告)号：US5861399A

    公开(公告)日：1999-01-19

    申请号：US680684

    申请日：1996-07-17

    申请人： Brian Seed ,  John C. Seed

    发明人： Brian Seed ,  John C. Seed

    IPC分类号： A61K31/505 ,  A61K31/506 ,  A61K31/60 ,  A61K31/785 ,  A61K31/495 ,  A61K31/40 ,  A61K31/44 ,  A61K31/50

    CPC分类号： A61K31/505 ,  A61K31/506 ,  A61K31/60 ,  A61K31/785 ,  Y10S514/824

    摘要： Disclosed are methods and compositions for reducing coronary artery stenosis, restoring blood flow to infarcted myocardium, improving myocardial perfusion, reducing heart attacks or other adverse cardiovascular events, or treating symptoms of inadequate myocardial function in a mammal involving administering to the mammal (a) a compound that includes eicosapentaeneoic acid or docosahexaeneoic acid and (b) a cholesterol-lowering therapeutic, combined with dietary restrictions (resulting in aggressive loading of marine lipids), whereby a serum LDL concentration of less than 75 mg/dl (and preferably less than 55 mg/dl) is achieved. One particular method involves administering to the mammal a combination that includes (a) a compound that includes an eicosapentaeneoic or docosahexaeneoic acid (for example, a marine lipid) and (b) a cholesterol synthesis or transfer inhibitor, and which may also optionally include aspirin and/or niacin. The methods and compositions of the invention may also further include a bile acid sequestrant and/or buspirone. Also disclosed are methods for treating heart disease that involve administration of buspirone.

    Methods and compositions for the rapid and enduring relief of inadequate myocardial function
    3.
    发明授权
    Methods and compositions for the rapid and enduring relief of inadequate myocardial function 有权

    公开(公告)号：US07109206B2

    公开(公告)日：2006-09-19

    申请号：US09735024

    申请日：2000-12-12

    申请人： Brian Seed ,  John C. Seed

    发明人： Brian Seed ,  John C. Seed

    IPC分类号： A61K31/505 ,  A61K31/44 ,  A61K31/40 ,  A61K31/35 ,  A61K31/21

    CPC分类号： A61K31/505 ,  A61K31/506 ,  A61K31/60 ,  A61K31/785 ,  Y10S514/824 ,  A61K2300/00

    摘要： Disclosed are methods and compositions for reducing coronary artery stenosis, restoring blood flow to infarcted myocardium, improving myocardial perfusion, reducing heart attacks or other adverse cardiovascular events, or treating symptoms of inadequate myocardial function in a mammal involving administering to the mammal (a) a compound that includes eicosapentaeneoic acid or docosahexaeneoic acid and (b) a cholesterol-lowering therapeutic, combined with dietary restrictions (resulting in aggressive loading of marine lipids), whereby a serum LDL concentration of less than 75 mg/dl (and preferably less than 55 mg/dl) is achieved. One particular method involves administering to the mammal a combination that includes (a) a compound that includes an eicosapentaeneoic or docosahexaeneoic acid (for example, a marine lipid) and (b) a cholesterol synthesis or transfer inhibitor, and which may also optionally include aspirin and/or niacin. The methods and compositions of the invention may also further include a bile acid sequestrant and/or buspirone. Also disclosed are methods for treating heart disease that involve administration of buspirone.

    Methods and compositions for the rapid and enduring relief of inadequate myocardial function
    4.
    发明授权
    Methods and compositions for the rapid and enduring relief of inadequate myocardial function 有权

    公开(公告)号：US06159993A

    公开(公告)日：2000-12-12

    申请号：US198874

    申请日：1998-11-24

    申请人： Brian Seed ,  John C. Seed

    发明人： Brian Seed ,  John C. Seed

    IPC分类号： A61K31/505 ,  A61K31/506 ,  A61K31/60 ,  A61K31/785 ,  A61K31/20 ,  A61K31/04

    CPC分类号： A61K31/505 ,  A61K31/506 ,  A61K31/60 ,  A61K31/785 ,  Y10S514/824 ,  A61K2300/00

    摘要： Disclosed are methods and compositions for reducing coronary artery stenosis, restoring blood flow to infarcted myocardium, improving myocardial perfusion, reducing heart attacks or other adverse cardiovascular events, or treating symptoms of inadequate myocardial function in a mammal involving administering to the mammal (a) a compound that includes eicosapentaeneoic acid or docosahexaeneoic acid and (b) a cholesterol-lowering therapeutic, combined with dietary restrictions (resulting in aggressive loading of marine lipids), whereby a serum LDL concentration of less than 75 mg/dl (and preferably less than 55 mg/dl) is achieved. One particular method involves administering to the mammal a combination that includes (a) a compound that includes an eicosapentaeneoic or docosahexaeneoic acid (for example, a marine lipid) and (b) a cholesterol synthesis or transfer inhibitor, and which may also optionally include aspirin and/or niacin. The methods and compositions of the invention may also further include a bile acid sequestrant and/or buspirone. Also disclosed are methods for treating heart disease that involve administration of buspirone.

    Method of assisting weight loss
    5.
    发明授权
    Method of assisting weight loss 失效
    协助减肥的方法

    公开(公告)号：US4895845A

    公开(公告)日：1990-01-23

    申请号：US907837

    申请日：1986-09-15

    申请人： John C. Seed

    发明人： John C. Seed

    IPC分类号： A61K31/475 ,  A61K45/06

    CPC分类号： A61K45/06 ,  A61K31/475 ,  Y10S514/91

    摘要： A method of assisting weight loss involving the combined administration of a rauwolfia alkaloid and at least one antidepressant, selected from the groups consisting of aminoazoles, phenoxyphenylpropylamines, and aminopropiophenones, in a daily regimen with the optional co-administration of one or more sympathomimetic anorexic agents. In a typical embodiment of this method, reserpine and trazodone are administered in a daily regimen with diethylpropion, fenfluramine or both diethylpropion and fenfluramine.

    摘要翻译： 一种辅助减肥的方法，其涉及在每日方案中选择由氨基咔唑，苯氧基苯丙基胺和氨基苯丙酮组成的组中的至少一种抗癫痫药物组合施用，任选地共同施用一种或多种拟交感神经厌食症剂 。 在该方法的典型实施方案中，利血平和曲唑酮以每日方案与二乙基丙酸，芬氟拉明或二丙酸和芬氟拉明两者一起施用。