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公开(公告)号:US20050209602A1
公开(公告)日:2005-09-22
申请号:US10984566
申请日:2004-11-09
申请人: Bruce Bowman , Robert Kohler , Erik Martz , Daniel Melink , Khin Myint , Michael Ahrens , Jean-Charles Lehuec , John Sherman , Scott Hook , Dennis Johnson , Qi-Bin Bao , Robert Hudgins
发明人: Bruce Bowman , Robert Kohler , Erik Martz , Daniel Melink , Khin Myint , Michael Ahrens , Jean-Charles Lehuec , John Sherman , Scott Hook , Dennis Johnson , Qi-Bin Bao , Robert Hudgins
CPC分类号: A61B17/8805 , A61B17/8827 , A61B17/8836 , A61B2090/064 , A61F2/441 , A61F2/4601 , A61F2/4611 , A61F2002/30062 , A61F2002/3008 , A61F2002/30583 , A61F2002/4627 , A61F2002/465 , A61F2002/4663 , A61F2002/467 , A61F2002/4677 , A61F2002/4688 , A61F2002/4693 , A61F2002/4694 , A61F2210/0004 , A61F2210/0085 , A61F2250/0098
摘要: A method and apparatus for fluidly coupling a reservoir containing a flowable biomaterial to a mold. The flow of the flowable biomaterial into the mold is controlled in accordance with a first operating parameter. At least one injection condition is monitored. The flow of the flowable biomaterial is controlled in accordance with a second operating parameter in response to one or more of the injection conditions reaching a threshold level. The second operating parameter is maintained during at least a portion of the curing of the flowable biomaterial. In some embodiments, the second operating parameter may optionally include permitting a portion of the flowable biomaterial to be expelled from the mold.
摘要翻译: 一种用于将包含可流动的生物材料的容器流体耦合到模具的方法和装置。 根据第一操作参数控制可流动的生物材料流入模具的流动。 至少监测一个注射条件。 响应于达到阈值水平的一个或多个注入条件,可流动生物材料的流动根据第二操作参数来控制。 在可流动的生物材料的固化的至少一部分期间维持第二操作参数。 在一些实施例中,第二操作参数可以可选地包括允许可流动的生物材料的一部分从模具中排出。
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公开(公告)号:US20050209601A1
公开(公告)日:2005-09-22
申请号:US10984493
申请日:2004-11-09
申请人: Bruce Bowman , Robert Kohler , Erik Martz , Daniel Melink , Khin Myint , Michael Ahrens , Jean-Charles Lehuec , John Sherman , Scott Hook , Dennis Johnson , Qi-Bin Bao , Robert Hudgins
发明人: Bruce Bowman , Robert Kohler , Erik Martz , Daniel Melink , Khin Myint , Michael Ahrens , Jean-Charles Lehuec , John Sherman , Scott Hook , Dennis Johnson , Qi-Bin Bao , Robert Hudgins
CPC分类号: A61B17/8805 , A61B17/8827 , A61B17/8836 , A61B2090/064 , A61F2/441 , A61F2/4601 , A61F2/4611 , A61F2002/30062 , A61F2002/3008 , A61F2002/30583 , A61F2002/4627 , A61F2002/465 , A61F2002/4663 , A61F2002/467 , A61F2002/4677 , A61F2002/4688 , A61F2002/4693 , A61F2002/4694 , A61F2210/0004 , A61F2210/0085 , A61F2250/0098
摘要: A method and apparatus for fluidly coupling a reservoir containing a flowable biomaterial to a mold. The flow of the flowable biomaterial into the mold is controlled in accordance with a first operating parameter. At least one injection condition is monitored. The flow of the flowable biomaterial is controlled in accordance with a second operating parameter in response to one or more of the injection conditions reaching a threshold level. The second operating parameter is maintained during at least a portion of the curing of the flowable biomaterial. In some embodiments, the second operating parameter may optionally include permitting a portion of the flowable biomaterial to be expelled from the mold.
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公开(公告)号:US08029511B2
公开(公告)日:2011-10-04
申请号:US10984493
申请日:2004-11-09
申请人: Bruce R. Bowman , Rob Kohler , Erik Martz , Dan Melink , Khin Myint , Michael Ahrens , Jean-Charles Lehuec , John Sherman , Scott Hook , Dennis Johnson , Qi-Bin Bao , Robert Garryl Hudgins
发明人: Bruce R. Bowman , Rob Kohler , Erik Martz , Dan Melink , Khin Myint , Michael Ahrens , Jean-Charles Lehuec , John Sherman , Scott Hook , Dennis Johnson , Qi-Bin Bao , Robert Garryl Hudgins
CPC分类号: A61B17/8805 , A61B17/8827 , A61B17/8836 , A61B2090/064 , A61F2/441 , A61F2/4601 , A61F2/4611 , A61F2002/30062 , A61F2002/3008 , A61F2002/30583 , A61F2002/4627 , A61F2002/465 , A61F2002/4663 , A61F2002/467 , A61F2002/4677 , A61F2002/4688 , A61F2002/4693 , A61F2002/4694 , A61F2210/0004 , A61F2210/0085 , A61F2250/0098
摘要: A method and apparatus for fluidly coupling a reservoir containing a flowable biomaterial to a mold. The flow of the flowable biomaterial into the mold is controlled in accordance with a first operating parameter. At least one injection condition is monitored. The flow of the flowable biomaterial is controlled in accordance with a second operating parameter in response to one or more of the injection conditions reaching a threshold level. The second operating parameter is maintained during at least a portion of the curing of the flowable biomaterial. In some embodiments, the second operating parameter may optionally include permitting a portion of the flowable biomaterial to be expelled from the mold.
摘要翻译: 一种用于将包含可流动的生物材料的容器流体耦合到模具的方法和装置。 根据第一操作参数控制可流动的生物材料流入模具的流动。 至少监测一个注射条件。 响应于达到阈值水平的一个或多个注入条件,可流动生物材料的流动根据第二操作参数来控制。 在可流动的生物材料的固化的至少一部分期间维持第二操作参数。 在一些实施例中,第二操作参数可以可选地包括允许可流动的生物材料的一部分从模具中排出。
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公开(公告)号:US20090076518A1
公开(公告)日:2009-03-19
申请号:US12266301
申请日:2008-11-06
申请人: Bruce R. Bowman , Rob Kohler , Erik Martz , Dan Melink , Khin Myint , Michael Ahrens , Jean-Charles Lehuec , John Sherman , Scott Hook , Dennis Johnson , Qi-Bin Bao , Robert Garryl Hudgins
发明人: Bruce R. Bowman , Rob Kohler , Erik Martz , Dan Melink , Khin Myint , Michael Ahrens , Jean-Charles Lehuec , John Sherman , Scott Hook , Dennis Johnson , Qi-Bin Bao , Robert Garryl Hudgins
CPC分类号: A61B17/8805 , A61B17/8827 , A61B17/8836 , A61B2090/064 , A61F2/441 , A61F2/4601 , A61F2/4611 , A61F2002/30062 , A61F2002/3008 , A61F2002/30583 , A61F2002/4627 , A61F2002/465 , A61F2002/4663 , A61F2002/467 , A61F2002/4677 , A61F2002/4688 , A61F2002/4693 , A61F2002/4694 , A61F2210/0004 , A61F2210/0085 , A61F2250/0098
摘要: A method of stabilizing adjacent vertebrae including the steps of forming at least one annulotomy in an annulus. At least a portion of the nucleus material is removed through the annulotomy to form a cavity in an intervertebral disc space between the adjacent vertebrae. A reservoir containing a flowable biomaterial is fluidly coupled to the intervertebral disc space. A flowable biomaterial is delivered to the cavity. The delivery of the flowable biomaterial into the intervertebral disc space is controlled in accordance with at least a first operating parameter. The biomaterial is at least partially cured to stabilize the adjacent vertebrae.
摘要翻译: 一种稳定相邻椎骨的方法,包括在环空中形成至少一个瓣膜切开术的步骤。 至少一部分细胞核材料通过瓣膜切开术去除以在相邻椎骨之间的椎间盘间隙中形成空腔。 包含可流动的生物材料的储存器流体耦合到椎间盘空间。 可流动的生物材料被输送到空腔。 根据至少第一操作参数控制可流动的生物材料输送到椎间盘空间中。 生物材料至少部分固化以稳定相邻的椎骨。
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公开(公告)号:US20060253200A1
公开(公告)日:2006-11-09
申请号:US11428120
申请日:2006-06-30
申请人: Qi-Bin Bao , Robert Hudgins , Jeffrey Felt , Alexander Arsenyev , Hansen Yuan
发明人: Qi-Bin Bao , Robert Hudgins , Jeffrey Felt , Alexander Arsenyev , Hansen Yuan
IPC分类号: A61F2/44
CPC分类号: C08G18/4854 , A61B1/00165 , A61B17/00234 , A61B17/16 , A61B17/17 , A61B17/7097 , A61B2017/00535 , A61F2/07 , A61F2/28 , A61F2/30756 , A61F2/30767 , A61F2/3099 , A61F2/32 , A61F2/38 , A61F2/4081 , A61F2/4202 , A61F2/441 , A61F2/442 , A61F2/4601 , A61F2/4611 , A61F2/82 , A61F2/945 , A61F2002/30016 , A61F2002/30024 , A61F2002/3008 , A61F2002/30235 , A61F2002/30563 , A61F2002/30578 , A61F2002/30583 , A61F2002/30601 , A61F2002/30841 , A61F2002/30929 , A61F2002/30957 , A61F2002/4233 , A61F2002/444 , A61F2002/4627 , A61F2002/4635 , A61F2210/0085 , A61F2230/0069 , A61F2250/0019 , A61F2250/0021 , A61F2250/0098 , A61L27/18 , A61L29/041 , A61L29/06 , A61L2430/38 , B01F2215/0039 , C08G18/10 , C08G18/69 , Y10S606/907 , Y10S606/91 , C08L83/04 , C08L75/04 , C08L23/00 , C08L67/02 , C08G18/3206
摘要: A method of treating a diseased or damaged intervertebral disc having a nucleus pulposus and an annulus. The method includes the steps of accessing and preparing the intervertebral disc for receipt of the biomaterial by removing at least a portion of the nucleus pulposus to create a nuclear cavity. A quantity of the curable biomaterial is delivered under pressure to the nuclear cavity. The delivered biomaterial is at least partially cured in such a manner to retain it in the nuclear cavity. The at least partially cured biomaterial is contoured to achieve a desired conformation approximating that of the nuclear cavity.
摘要翻译: 一种治疗患有或受损的具有髓核和环的椎间盘的方法。 该方法包括以下步骤:通过去除髓核的至少一部分以产生核腔来获取和准备用于接收生物材料的椎间盘。 一定量的可固化生物材料在压力下输送到核腔。 递送的生物材料至少部分地固化,以将其保持在核腔中。 所述至少部分固化的生物材料的轮廓是实现与核腔近似的所需构型。
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公开(公告)号:US20070038300A1
公开(公告)日:2007-02-15
申请号:US11277887
申请日:2006-03-29
申请人: Qi-Bin Bao , Robert Hudgins , Jeffrey Felt , Alexander Arsenyev , Hansen Yuan
发明人: Qi-Bin Bao , Robert Hudgins , Jeffrey Felt , Alexander Arsenyev , Hansen Yuan
CPC分类号: C08G18/4854 , A61B1/00165 , A61B17/00234 , A61B17/16 , A61B17/17 , A61B17/7097 , A61B2017/00535 , A61F2/07 , A61F2/28 , A61F2/30756 , A61F2/30767 , A61F2/3099 , A61F2/32 , A61F2/38 , A61F2/4081 , A61F2/4202 , A61F2/441 , A61F2/442 , A61F2/4601 , A61F2/4611 , A61F2/82 , A61F2/945 , A61F2002/30016 , A61F2002/30024 , A61F2002/3008 , A61F2002/30235 , A61F2002/30563 , A61F2002/30578 , A61F2002/30583 , A61F2002/30601 , A61F2002/30841 , A61F2002/30929 , A61F2002/30957 , A61F2002/4233 , A61F2002/444 , A61F2002/4627 , A61F2002/4635 , A61F2210/0085 , A61F2230/0069 , A61F2250/0019 , A61F2250/0021 , A61F2250/0098 , A61L27/18 , A61L29/041 , A61L29/06 , A61L2430/38 , B01F2215/0039 , C08G18/10 , C08G18/69 , Y10S606/907 , Y10S606/91 , C08L83/04 , C08L75/04 , C08L23/00 , C08L67/02 , C08G18/3206
摘要: A system for repairing an intervertebral disc by delivering and curing a biomaterial in situ within the disc. The system includes both a device, having an insertable balloon and related lumen, controls and adapters, as well as an in situ curable biomaterial (and related biomaterial delivery means). The system can allow the doctor to determine a suitable endpoint for biomaterial delivery, by controlling distraction and/or biomaterial delivery pressure, and in turn, to deliver a desired quantity of biomaterial to the balloon in order to achieve improved polymer cure and implant characteristics. Also provided is a related method for repairing an intervertebral disc by using such a system to deliver and cure the biomaterial in situ. The system can be used to implant a prosthetic total disc, or a prosthetic disc nucleus in a manner that leaves the surrounding disc tissue substantially intact.
摘要翻译: 一种通过在盘内原位递送和固化生物材料来修复椎间盘的系统。 该系统包括具有可插入球囊和相关内腔的装置,对照和适配器,以及原位可固化生物材料(和相关的生物材料递送装置)。 该系统可以允许医生通过控制牵引和/或生物材料输送压力来确定用于生物材料递送的合适的终点,并且反过来,将气体中所需量的生物材料输送到气囊中,以实现改进的聚合物固化和植入特征。 还提供了一种通过使用这种系统来原位递送和固化生物材料来修复椎间盘的相关方法。 该系统可以用于以使得周围的盘组织基本上完整的方式植入假体总盘或假体椎间盘细胞核。
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公开(公告)号:US09445916B2
公开(公告)日:2016-09-20
申请号:US11856565
申请日:2007-09-17
申请人: Qi-Bin Bao , Tim Brown
发明人: Qi-Bin Bao , Tim Brown
IPC分类号: A61F2/44 , A61F2/32 , A61F2/38 , A61F2/42 , A61L27/18 , A61L27/34 , A61B17/86 , A61F2/30 , A61F2/34 , A61F2/36 , A61F2/46
CPC分类号: A61F2/4425 , A61B17/86 , A61F2/30767 , A61F2/32 , A61F2/34 , A61F2/36 , A61F2/38 , A61F2/3859 , A61F2/389 , A61F2/4202 , A61F2/4405 , A61F2/468 , A61F2002/3008 , A61F2002/30383 , A61F2002/30387 , A61F2002/30487 , A61F2002/30604 , A61F2002/30685 , A61F2002/30772 , A61F2002/30787 , A61F2002/30841 , A61F2002/30843 , A61F2002/3085 , A61F2002/30892 , A61F2002/30894 , A61F2002/30904 , A61F2002/30934 , A61F2002/3401 , A61F2002/3411 , A61F2002/3429 , A61F2002/3493 , A61F2002/3611 , A61F2002/365 , A61F2002/4205 , A61F2002/4207 , A61F2002/444 , A61F2002/4631 , A61F2220/0025 , A61F2250/0098 , A61F2310/00005 , A61F2310/00011 , A61F2310/00389 , A61F2310/00407 , A61F2310/00796 , A61L27/18 , A61L27/34 , C08L71/12 , C08L71/00
摘要: Articulating devices for replacing damaged or degenerated weight bearing joints are provided. The devices may have two or more surfaces that articulate against one another that are coated or fully formed of PEEK or similar materials to provide improved wear capabilities while maintaining sufficient strength to operate in a weight bearing capacity.
摘要翻译: 提供用于更换损坏或退化的承重接头的铰接装置。 这些装置可以具有两个或更多个彼此铰接的表面,其被PEEK或类似材料涂覆或完全形成,以提供改进的磨损能力,同时保持足够的强度以承重能力运行。
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公开(公告)号:US08808382B2
公开(公告)日:2014-08-19
申请号:US11963727
申请日:2007-12-21
申请人: Qi-Bin Bao , Jeffrey L. Trudeau , Thomas S. Kilpela , Wade DePas , Allison Koskey , Brian P. Janowski
发明人: Qi-Bin Bao , Jeffrey L. Trudeau , Thomas S. Kilpela , Wade DePas , Allison Koskey , Brian P. Janowski
IPC分类号: A61F2/44
CPC分类号: A61F2/442 , A61F2002/30092 , A61F2002/30383 , A61F2002/30448 , A61F2002/30462 , A61F2002/30471 , A61F2002/30565 , A61F2002/30579 , A61F2002/30604 , A61F2002/30672 , A61F2002/444 , A61F2210/0014 , A61F2220/0025 , A61F2220/005 , A61F2220/0075 , A61F2220/0091
摘要: An implant retention device is provided to assist in restraining movement of a nuclear implant and to assist in preventing expulsion of the nuclear implant through an incision portal or defect in the annular wall. In one form, the implant retention device may include an elongated tensioning member having a portion configured to connect to the implant and at least one anchoring device disposed on the tensioning member, the anchoring device configured to at least partially penetrate spinal tissue such as the annulus, vertebral body, or other secure tissue.
摘要翻译: 提供植入物保持装置以帮助限制核植入物的运动,并且有助于防止核植入物通过切口入口或环形壁中的缺陷的排出。 在一种形式中,植入物保持装置可以包括细长的张紧构件,其具有构造成连接到植入物的部分和设置在张紧构件上的至少一个锚定装置,该锚定装置构造成至少部分地穿透脊髓组织,例如环 ,椎体或其他安全的组织。
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公开(公告)号:US08388684B2
公开(公告)日:2013-03-05
申请号:US10692468
申请日:2003-10-22
申请人: Qi-Bin Bao , Jeffrey L. Trudeau , Brian Patrick Janowski , Matthew N. Songer , Hansen Yuan , Thomas S. Kilpela , Gregory Berrevoets
发明人: Qi-Bin Bao , Jeffrey L. Trudeau , Brian Patrick Janowski , Matthew N. Songer , Hansen Yuan , Thomas S. Kilpela , Gregory Berrevoets
IPC分类号: A61F2/44
CPC分类号: A61F2/4684 , A61F2/30742 , A61F2/30965 , A61F2/442 , A61F2/4425 , A61F2/4611 , A61F2002/30014 , A61F2002/30016 , A61F2002/3008 , A61F2002/30113 , A61F2002/30123 , A61F2002/30125 , A61F2002/30133 , A61F2002/30158 , A61F2002/302 , A61F2002/3023 , A61F2002/30242 , A61F2002/30245 , A61F2002/30299 , A61F2002/30311 , A61F2002/30327 , A61F2002/30331 , A61F2002/30369 , A61F2002/30387 , A61F2002/3039 , A61F2002/30428 , A61F2002/30448 , A61F2002/30462 , A61F2002/30471 , A61F2002/30476 , A61F2002/30485 , A61F2002/305 , A61F2002/30507 , A61F2002/3052 , A61F2002/30528 , A61F2002/30538 , A61F2002/3054 , A61F2002/3055 , A61F2002/30556 , A61F2002/30563 , A61F2002/30565 , A61F2002/30574 , A61F2002/30581 , A61F2002/30583 , A61F2002/30586 , A61F2002/30588 , A61F2002/30604 , A61F2002/30616 , A61F2002/30649 , A61F2002/30662 , A61F2002/30673 , A61F2002/30685 , A61F2002/30738 , A61F2002/30784 , A61F2002/30841 , A61F2002/30919 , A61F2002/30934 , A61F2002/30935 , A61F2002/443 , A61F2002/444 , A61F2002/4627 , A61F2002/4628 , A61F2002/4681 , A61F2002/484 , A61F2210/0085 , A61F2220/0025 , A61F2220/0033 , A61F2220/005 , A61F2220/0075 , A61F2220/0091 , A61F2230/0006 , A61F2230/0008 , A61F2230/0015 , A61F2230/0026 , A61F2230/0065 , A61F2230/0069 , A61F2230/0071 , A61F2230/0093 , A61F2250/0006 , A61F2250/0009 , A61F2250/0018 , A61F2250/0019 , A61F2250/0039 , A61F2250/0098 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00179 , A61F2310/00203 , A61F2310/00239 , A61F2310/00574
摘要: An artificial disc device for replacing a damaged nucleus is disclosed. In one form, the device may be inserted in components such that the device may be assembled within and retained by the natural annulus therein. In another form, the device may be inserted into the natural annulus in a collapsed or compressed state or arrangement and then be expanded within and retained by the annulus therein.
摘要翻译: 公开了一种用于更换损坏的核的人造盘装置。 在一种形式中,装置可以插入到部件中,使得装置可以组装在其内的天然环中并由其中的天然环保持。 在另一种形式中,装置可以以塌缩或压缩状态或布置插入天然环形空间中,然后在其中被扩张并由其中的环保持。
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公开(公告)号:US08163019B2
公开(公告)日:2012-04-24
申请号:US11963745
申请日:2007-12-21
IPC分类号: A61F2/44
CPC分类号: A61F2/442 , A61F2002/30092 , A61F2002/30383 , A61F2002/30448 , A61F2002/30462 , A61F2002/30471 , A61F2002/30565 , A61F2002/30579 , A61F2002/30604 , A61F2002/30672 , A61F2002/444 , A61F2210/0014 , A61F2220/0025 , A61F2220/005 , A61F2220/0075 , A61F2220/0091
摘要: An implant retention device is provided to assist in restraining movement of a nuclear implant and to assist in preventing expulsion of the nuclear implant through an incision portal or defect in the annular wall. In general, the implant retention device blocks or obstructs at least a portion of an opening in the annular wall, thereby keeping the implant from exiting the nuclear space through the annular opening. In one form, the implant retention device comprises an expulsion prevention member positioned adjacent the nuclear implant and configured to transition between a compressed position and an expanded position. In another form, the implant retention device may comprise a mounting portion to be positioned adjacent one of the vertebral bodies, a blocking portion for at least partially obstructing the annular opening, and an end projection at a terminal end of the blocking portion to resist expulsion of the implant through the annular opening. In yet another form, the implant retention device may include an elongate blocking member having annulus connector portions extending from each side of the blocking member for engaging with an annular wall.
摘要翻译: 提供植入物保持装置以帮助限制核植入物的运动,并且有助于防止核植入物通过切口入口或环形壁中的缺陷的排出。 通常,植入物保持装置阻挡或阻挡环形壁中的开口的至少一部分,从而保持植入物不通过环形开口离开核空间。 在一种形式中,所述植入物保持装置包括与所述核植入物相邻定位并且构造成在压缩位置和扩张位置之间转变的防止排出构件。 在另一种形式中,植入物保持装置可以包括邻近一个椎体定位的安装部分,用于至少部分地阻挡环形开口的阻挡部分,以及阻挡部分末端的端部突出部以抵抗排出 的植入物通过环形开口。 在另一种形式中,植入物保持装置可以包括细长的阻挡构件,其具有从阻挡构件的每一侧延伸的环形连接器部分,用于与环形壁接合。
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