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公开(公告)号:US09974458B2
公开(公告)日:2018-05-22
申请号:US14158021
申请日:2014-01-17
IPC分类号: A61B5/0428 , A61B5/04 , A61B5/00
CPC分类号: A61B5/04017 , A61B5/04004 , A61B5/0428 , A61B5/7203
摘要: A method can include storing input electrical signal data representing at least a given electrophysiological signal acquired from a patient. A non-local mean filter can be applied to the given electrophysiological signal, the non-local mean filter including a spatial filter component and an intensity filter component. The method can also include controlling parameters to establish weighting of each of the spatial filter component and the intensity filter component in response to a control input. Filtered signal data can be stored based on the applying and the controlling.
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公开(公告)号:US09883813B2
公开(公告)日:2018-02-06
申请号:US15240725
申请日:2016-08-18
发明人: Qingguo Zeng , Rémi DuBois , Ping Jia , Ryan Bokan , Venkatesh Vasudevan , Charulatha Ramanathan , Maria Strom , Brian P. George
IPC分类号: A61B5/044 , A61B5/04 , A61B5/00 , A61B5/0452 , A61N1/36 , A61B5/046 , A61B5/0464 , A61B18/14 , A61B5/0408 , A61B5/042
CPC分类号: A61B5/04012 , A61B5/0044 , A61B5/04085 , A61B5/0422 , A61B5/044 , A61B5/0452 , A61B5/046 , A61B5/0464 , A61B5/486 , A61B5/7264 , A61B18/1492 , A61B2576/023 , A61N1/36
摘要: A method can determine one or more origins of focal activation. The method can include computing phase for the electrical signals at a plurality of nodes distributed across a geometric surface based on the electrical data across time. The method can determine whether or not a given candidate node of the plurality of nodes is a focal point based on the analyzing the computed phase and magnitude of the given candidate node. A graphical map can be generated to visualize focal points detected on the geometric surface.
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公开(公告)号:US09820666B2
公开(公告)日:2017-11-21
申请号:US14614219
申请日:2015-02-04
发明人: Ryan Bokan , Charulatha Ramanathan , Ping Jia , Maria Strom , Qingguo Zeng
IPC分类号: A61B5/044 , A61B5/00 , A61B5/0402 , A61B5/06 , A61B5/042
CPC分类号: A61B5/0452 , A61B5/02405 , A61B5/0245 , A61B5/04012 , A61B5/0402 , A61B5/042 , A61B5/044 , A61B5/06 , A61B5/066 , A61B5/4836 , A61B5/7264 , A61B5/743
摘要: A method can include analyzing non-invasive electrical data for a region of interest (ROI) of a patient's anatomical structure to identify one or more zones within the ROI that contain at least one mechanism of distinct arrhythmogenic electrical activity. The method also includes analyzing invasive electrical data for a plurality of signals of interest at different spatial sites within each of the identified zones to determine intracardiac signal characteristics for the plurality of sites within each respective zone. The method also includes generating an output that integrates the at least one mechanism of distinct arrhythmogenic electrical activity for the one or more zones with intracardiac signal characteristics for the plurality of sites within each respective zone.
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公开(公告)号:US20160242663A1
公开(公告)日:2016-08-25
申请号:US15048835
申请日:2016-02-19
发明人: Vivek Jayan , Ping Jia , Ryan Bokan , Charu Ramanathan , Qingguo Zeng , Torsten Konrad
IPC分类号: A61B5/046 , A61B5/04 , A61B18/12 , A61B5/00 , A61N1/365 , A61B5/0402 , A61B5/0408
CPC分类号: A61B5/046 , A61B5/04012 , A61B5/0402 , A61B5/0408 , A61B5/18 , A61B5/4836 , A61B5/7275 , A61B18/1206 , A61B18/1492 , A61B2018/00357 , A61B2018/00363 , A61B2018/00577 , A61B2018/0072 , A61B2018/00767 , A61B2018/00994 , A61B2018/0212 , A61N1/365
摘要: A system includes an input to receive at least one electrophysiological signal representing cardiac electrical activity measured from a body surface of a patient. The system also includes a signal processor to analyze the at least one electrophysiological signal and compute a score having a value to indicate a likelihood of arrhythmogenic activity, the score being computed as a function of at least two of cycle length, amplitude and polarity of the at least one signal.
摘要翻译: 系统包括用于接收表示从患者的身体表面测量的心脏电活动的至少一个电生理信号的输入。 所述系统还包括信号处理器,用于分析所述至少一个电生理信号并计算具有指示致心律失常活动可能性的值的得分,所述评分作为所述周期长度,振幅和极性中的至少两个的函数计算 至少一个信号。
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公开(公告)号:US11284830B2
公开(公告)日:2022-03-29
申请号:US16774662
申请日:2020-01-28
发明人: Qing Lou , Meredith E. Stone , Qingguo Zeng , Jeffrey B. Adair , Connor S. Edel , Ping Jia , Kevin R. Ponziani , Brian P. George , Ryan M. Bokan , Matthew J. Sabo , Vladimir A. Turovskiy , Ketal C. Patel , Charulatha Ramanathan
IPC分类号: A61B5/364 , A61B5/00 , G16H50/30 , G16H40/63 , A61B5/282 , A61B5/316 , A61B5/333 , A61B5/339 , A61B5/366 , G16H50/20 , A61B5/361 , A61B5/363
摘要: An example method includes analyzing morphology and/or amplitude of each of a plurality of electrophysiological signals across a surface of a patient's body to identify candidate segments of each signal satisfying predetermined conduction pattern criteria. The method also includes determining a conduction timing parameter for each candidate segment in each of the electrophysiological signals.
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公开(公告)号:US10482680B2
公开(公告)日:2019-11-19
申请号:US14158320
申请日:2014-01-17
IPC分类号: G06T19/20 , A61B5/00 , A61B5/0432 , A61B5/0476 , G09B23/30 , G06T11/00 , A61B18/14 , A61N1/362 , A61N7/02 , A61B17/00 , A61B18/00 , A61B18/02 , A61B90/00
摘要: A map generator can be programmed to generate a multi-parameter graphical map by encoding at least two different physiological parameters for a geometric surface, corresponding to tissue of a patient, using different color components of a multi-dimensional color model such that each of the different physiological parameters is encoded by at least one of the different color components.
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公开(公告)号:US10323922B2
公开(公告)日:2019-06-18
申请号:US14841198
申请日:2015-08-31
发明人: Qingguo Zeng , Ping Jia , Charulatha Ramanathan , Lijun Yu , Jeff Burrell , Brian George , Qing Lou , Ryan Bokan , Soniya Bhojwani
摘要: This disclosure relates to localization and tracking of an object. As one example, measurement data can be stored in memory to represent measured electrical signals at each of a plurality of known measurement locations in a given coordinate system in response to an applied signal at an unknown location in the given coordinate system. A dipole model cost function has parameters representing a dipole location and moment corresponding to the applied signal. A boundary condition can be imposed on the dipole model cost function. The unknown location in the given coordinate system, corresponding to the dipole location, can then be determined based on the stored measurement data and the dipole model cost function with the boundary condition imposed thereon.
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公开(公告)号:US10117594B2
公开(公告)日:2018-11-06
申请号:US15240636
申请日:2016-08-18
发明人: Qingguo Zeng , Ping Jia , Ryan Bokan , Brian P. George , Charulatha Ramanathan , Venkatesh Vasudevan , Maria Strom
IPC分类号: A61B5/0452 , A61B18/02 , A61B18/14 , A61B34/10 , A61N1/05 , A61N1/362 , A61N7/00 , G06F19/00 , G06F17/50 , A61B18/04 , G16H50/50 , A61B18/00
摘要: Systems and methods are provided to detect and analyze arrhythmia drivers. In one example, a system can include a wave front analyzer programmed to compute wave front lines extending over a surface for each of the plurality of time samples based on phase information computed from electrical data at nodes distributed across the surface. A trajectory detector can be programmed to compute wave break points for each of the wave front lines and to determine a trajectory of at least one rotor core across the surface. A stability detector can be programmed to identify at least one stable rotor portion corresponding to subtrajectories of the determined trajectory.
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公开(公告)号:US09433364B2
公开(公告)日:2016-09-06
申请号:US14156903
申请日:2014-01-16
发明人: Qingguo Zeng , Remi Dubois , Ping Jia , Ryan Bokan , Venkatesh Vasudevan , Charulatha Ramanathan , Maria Strom , Brian P. George
摘要: A method can determine one or more origins of focal activation. The method can include computing phase for the electrical signals at a plurality of nodes distributed across a geometric surface based on the electrical data across time. The method can determine whether or not a given candidate node of the plurality of nodes is a focal point based on the analyzing the computed phase and magnitude of the given candidate node. A graphical map can be generated to visualize focal points detected on the geometric surface.
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公开(公告)号:US09427169B2
公开(公告)日:2016-08-30
申请号:US14273458
申请日:2014-05-08
发明人: Qingguo Zeng , Ping Jia , Ryan Bokan , Brian P. George , Charulatha Ramanathan , Venkatesh Vasudevan , Maria Strom
IPC分类号: A61B5/0452 , G06F17/50 , A61N7/00 , A61B18/04 , A61B18/14 , A61B18/00 , A61B18/02 , A61N1/05 , A61N1/362
CPC分类号: A61B5/0452 , A61B18/02 , A61B18/04 , A61B18/1492 , A61B34/10 , A61B2018/00839 , A61B2018/0212 , A61B2034/105 , A61N1/056 , A61N1/3622 , A61N7/00 , A61N2007/0043 , G06F17/50 , G06F19/00 , G16H50/50
摘要: Systems and methods are provided to detect and analyze arrhythmia drivers. In one example, a system can include a wave front analyzer programmed to compute wave front lines extending over a surface for each of the plurality of time samples based on phase information computed from electrical data at nodes distributed across the surface. A trajectory detector can be programmed to compute wave break points for each of the wave front lines and to determine a trajectory of at least one rotor core across the surface. A stability detector can be programmed to identify at least one stable rotor portion corresponding to subtrajectories of the determined trajectory.
摘要翻译: 提供系统和方法来检测和分析心律失常司机。 在一个示例中,系统可以包括波前分析器,其被编程为基于根据分布在表面上的节点处的电数据计算的相位信息来计算在多个时间样本中的每一个上的表面上延伸的波前线。 可以对轨迹检测器进行编程,以计算每个波前线的波形断点并确定穿过该表面的至少一个转子芯的轨迹。 可以对稳定性检测器进行编程以识别对应于所确定的轨迹的减速器的至少一个稳定的转子部分。
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