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公开(公告)号：US10662450B2
公开(公告)日：2020-05-26
申请号：US16344189
申请日：2018-06-29
发明人： Hyung Joon Kim , Hyo Jin Kim , Hyun Won Bae , Hyun Ah Kim , Chang Il Seo , Ji Sun Lee , Jin Sook Chang
摘要： An aspartokinase variant, a microorganism comprising the variant, and a method for producing an aspartate-derived L-amino acid or a homoserine derivative thereof using the microorganism.
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公开(公告)号：US10316339B2
公开(公告)日：2019-06-11
申请号：US15031706
申请日：2014-10-22
发明人： Su Jin Choi , So Young Kim , Chang Il Seo , Yong Uk Shin , Young Lyeol Yang , Hye Won Um , Hye Min Park , Sung Hoo Jhon , Byung Hoon Jung
摘要： The present invention relates to a polypeptide having a resistant to feedback inhibition by methionine and an activity of homoserine O-succinyltransferase, a O-succinyl homoserine-producing microorganism expressing the polypeptide, and a method for producing O-succinyl homoserine using the same.
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3.发明授权公开(公告)号：US11524981B2
公开(公告)日：2022-12-13
申请号：US17268691
申请日：2020-03-20
发明人： Moo Young Jung , Hyun Ah Kim , Chang Il Seo , Imsang Lee , Ji-won Kim , Tae Yeon Kim , Sung Kwang Son , Ki Yong Cheong
摘要： The present disclosure relates to a protein variant having a tryptophan-exporting activity, an L-tryptophan-producing microorganism expressing the protein variant, and a method for producing L-tryptophan using the microorganism.
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4.发明申请公开(公告)号：US20200248218A1
公开(公告)日：2020-08-06
申请号：US15769920
申请日：2016-10-21
发明人： Chang Il Seo , Hye Min Park , Kwang Ho Lee , Sang Min Park , Kyung Rim Kim , Ki Yong Cheong
摘要： The present disclosure relates to a recombinant microorganism producing threonine, and a method for producing L-threonine using the same.
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公开(公告)号：US10221434B2
公开(公告)日：2019-03-05
申请号：US15031707
申请日：2014-10-22
发明人： Chang Il Seo , So Young Kim , Yong Uk Shin , Kwang Ho Na , Hye Won Um , In Kyung Heo
摘要： The present invention relates to a polypeptide which is resistant to feedback inhibition by methionine and has an activity of homoserine O-succinyltransferase, a microorganism for producing O-succinylhomoserine which expresses the polypeptide, and a method for producing O-succinylhomoserine using the same.
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6.发明授权Microorganisms for production of O-succinylhomoserine and method for production of O-succinylhomoserine using the same 有权用于生产O-琥珀酰高丝氨酸的微生物及使用其的O-琥珀酰高丝氨酸的生产方法公开(公告)号：US09593353B2
公开(公告)日：2017-03-14
申请号：US15031703
申请日：2014-10-22
发明人： Su Jin Choi , So Young Kim , Chang Il Seo , Yong Uk Shin , Young Lyeol Yang , Hye Won Um , Hye Min Park , Sung Hoo Jhon , Byung Hoon Jung
CPC分类号： C12P13/06 , C12N9/1029 , C12Y203/01046 , Y02P20/52
摘要： The present invention relates to a polypeptide having a resistant to feedback inhibition by methionine and an activity of homoserine O-succinyltransferase, a O-succinyl homoserine-producing microorganism expressing the polypeptide, and a method for producing O-succinyl homoserine using the same.
摘要翻译： 本发明涉及具有抗甲硫氨酸反馈抑制和高丝氨酸O-琥珀酰基转移酶的活性的多肽，表达该多肽的产生O-琥珀酰高丝氨酸的微生物的活性，以及使用该多肽产生O-琥珀酰高丝氨酸的方法。
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公开(公告)号：US11603534B2
公开(公告)日：2023-03-14
申请号：US16959827
申请日：2019-03-15
发明人： Jee Yeon Bae , Chang Il Seo , Inhwa Yoo , Hye Ryun Yoo , So Young Kim , Yong Uk Shin
摘要： Provided are promoters and a method of producing L-amino acid using the same.
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公开(公告)号：US20220195470A1
公开(公告)日：2022-06-23
申请号：US17430314
申请日：2020-06-17
发明人： Gyuhyeon Song , Chang Il Seo , Nara Kwon
摘要： The present disclosure relates to an L-tyrosine-producing microorganism, comprising a trp operon regulatory region and a gene encoding prephenate dehydratase operably linked thereto, and a method for producing L-tyrosine using the microorganism.
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9.发明申请Method for Increasing the Solubility of Methionine by Mineral Addition and Acid Treatment 审中-公开通过矿物添加和酸处理提高甲硫氨酸的溶解度的方法公开(公告)号：US20170016037A1
公开(公告)日：2017-01-19
申请号：US15282416
申请日：2016-09-30
发明人： So Young Kim , Yong Uk Shin , In Kyung Heo , Hyun Ah Kim , Ju Eun Kim , Chang Il Seo , Sung Kwang Son , Sang Mok Lee , Sung Hoo Jhon , Han Jin Lee , Kwang Ho Na , Il Chul Kim
IPC分类号： C12P13/12 , A23L33/175 , A61K47/02 , A61K9/08 , A61K31/20
CPC分类号： C12P13/12 , A23L33/175 , A23V2002/00 , A61K9/08 , A61K31/20 , A61K47/02 , C07C319/26 , C07C323/52
摘要： The present invention relates to a method for enhancing the solubility of methionine. More particularly, the present invention relates to a method for increasing the solubility of methionine, in which mineral and sulfuric acid are added at an appropriate ratio to enhance the methionine solubility, thereby overcoming the problem of low solubility of methionine in water.
摘要翻译： 本发明涉及提高甲硫氨酸溶解度的方法。 更具体地说，本发明涉及增加甲硫氨酸的溶解度的方法，其中以适当的比例加入矿物和硫酸以提高甲硫氨酸的溶解度，从而克服了蛋氨酸在水中溶解度低的问题。
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公开(公告)号：US11697673B2
公开(公告)日：2023-07-11
申请号：US16956799
申请日：2019-07-25
发明人： Seok Myung Lee , Ki Yong Cheong , Chang Il Seo , Ji Sun Lee
CPC分类号： C07K14/245 , C12N1/205 , C12P13/08 , C12P13/22 , C12R2001/19
摘要： The present disclosure relates to a variant of cAMP receptor protein of Escherichia coli with alanine at position 35, a microorganism including the same, and a method of producing an L-amino acid using the same.
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