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公开(公告)号：US09718058B2
公开(公告)日：2017-08-01
申请号：US15336487
申请日：2016-10-27
申请人： CUE INC.
发明人： Ayub Khattak , Clinton Sever , Paul Nelson , Ryan Cooper , Thomas Congdon , Justin Demartino , Raphael Shapiro , Mark Duncan
IPC分类号： B01L3/00 , G01N35/10 , G01N27/327 , G01N35/00 , G01N33/543 , C12Q1/68
CPC分类号： B01L3/508 , B01L3/5023 , B01L3/5027 , B01L3/502715 , B01L3/502738 , B01L3/5029 , B01L3/523 , B01L2200/025 , B01L2200/027 , B01L2200/0668 , B01L2200/0684 , B01L2200/0689 , B01L2200/10 , B01L2200/14 , B01L2200/16 , B01L2300/023 , B01L2300/047 , B01L2300/0627 , B01L2300/0645 , B01L2300/0663 , B01L2300/0672 , B01L2300/069 , B01L2300/0809 , B01L2300/0816 , B01L2300/0867 , B01L2300/087 , B01L2300/1805 , B01L2300/1827 , B01L2400/0406 , B01L2400/0481 , B01L2400/0677 , C12Q1/6825 , G01N27/3273 , G01N33/54366 , G01N35/0098 , G01N35/10
摘要： Devices, systems, and methods for detecting molecules of interest within a collected sample are described herein. In certain embodiments, self-contained sample analysis systems are disclosed, which include a reusable reader component, a disposable cartridge component, and a disposable sample collection component. The reader component may communicate with a remote computing device for the digital transmission of test protocols and test results. In various disclosed embodiments, the systems, components, and methods are configured to identify the presence, absence, and/or quantity of particular nucleic acids, proteins, or other analytes of interest, for example, in order to test for the presence of one or more pathogens or contaminants in a sample.
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2.发明申请CIRCUIT BOARDS, CARTRIDGES HAVING THE SAME, KITS, AND METHODS FOR ENHANCED DETECTION AND QUANTIFICATION OF ANALYTES 有权电路板，具有它们的盒子，用于增强分析仪检测和定量的盒子和方法公开(公告)号：US20170043342A1
公开(公告)日：2017-02-16
申请号：US15336715
申请日：2016-10-27
申请人： CUE INC.
发明人： Ayub Khattak , Clinton Sever , Paul Nelson , Ryan Cooper , Thomas Congdon , Justin Demartino , Raphael Shapiro , Mark Duncan
IPC分类号： B01L3/00
CPC分类号： B01L3/508 , B01L3/5023 , B01L3/5027 , B01L3/502715 , B01L3/502738 , B01L3/5029 , B01L3/523 , B01L2200/025 , B01L2200/027 , B01L2200/0668 , B01L2200/0684 , B01L2200/0689 , B01L2200/10 , B01L2200/14 , B01L2200/16 , B01L2300/023 , B01L2300/047 , B01L2300/0627 , B01L2300/0645 , B01L2300/0663 , B01L2300/0672 , B01L2300/069 , B01L2300/0809 , B01L2300/0816 , B01L2300/0867 , B01L2300/087 , B01L2300/1805 , B01L2300/1827 , B01L2400/0406 , B01L2400/0481 , B01L2400/0677 , C12Q1/6825 , G01N27/3273 , G01N33/54366 , G01N35/0098 , G01N35/10
摘要： Devices, systems, and methods for detecting molecules of interest within a collected sample are described herein. In certain embodiments, self-contained sample analysis systems are disclosed, which include a reusable reader component, a disposable cartridge component, and a disposable sample collection component. The reader component may communicate with a remote computing device for the digital transmission of test protocols and test results. In various disclosed embodiments, the systems, components, and methods are configured to identify the presence, absence, and/or quantity of particular nucleic acids, proteins, or other analytes of interest, for example, in order to test for the presence of one or more pathogens or contaminants in a sample.
摘要翻译： 在本文中描述了用于检测收集的样品中的感兴趣分子的装置，系统和方法。 在某些实施例中，公开了自包含的样品分析系统，其包括可重复使用的读取器部件，一次性药筒部件和一次性样品收集部件。 读取器组件可以与远程计算设备通信，用于测试协议和测试结果的数字传输。 在各种公开的实施方案中，系统，组分和方法被配置为鉴定特定核酸，蛋白质或其他感兴趣的分析物的存在，不存在和/或数量，例如为了测试一种 或更多的病原体或污染物。
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公开(公告)号：US20180104682A1
公开(公告)日：2018-04-19
申请号：US15664904
申请日：2017-07-31
申请人： CUE INC.
发明人： Ayub Khattak , Clinton Sever , Paul Nelson , Ryan Cooper , Thomas Congdon , Justin Demartino , Raphael Shapiro , Mark Duncan
IPC分类号： B01L3/00 , G01N35/10 , G01N33/543 , G01N27/327 , G01N35/00
CPC分类号： B01L3/508 , B01L3/5023 , B01L3/5027 , B01L3/502715 , B01L3/502738 , B01L3/5029 , B01L3/523 , B01L2200/025 , B01L2200/027 , B01L2200/0668 , B01L2200/0684 , B01L2200/0689 , B01L2200/10 , B01L2200/14 , B01L2200/16 , B01L2300/023 , B01L2300/047 , B01L2300/0627 , B01L2300/0645 , B01L2300/0663 , B01L2300/0672 , B01L2300/069 , B01L2300/0809 , B01L2300/0816 , B01L2300/0867 , B01L2300/087 , B01L2300/1805 , B01L2300/1827 , B01L2400/0406 , B01L2400/0481 , B01L2400/0677 , C12Q1/6825 , G01N27/3273 , G01N33/54366 , G01N35/0098 , G01N35/10
摘要： Devices, systems, and methods for detecting molecules of interest within a collected sample are described herein. In certain embodiments, self-contained sample analysis systems are disclosed, which include a reusable reader component, a disposable cartridge component, and a disposable sample collection component. The reader component may communicate with a remote computing device for the digital transmission of test protocols and test results. In various disclosed embodiments, the systems, components, and methods are configured to identify the presence, absence, and/or quantity of particular nucleic acids, proteins, or other analytes of interest, for example, in order to test for the presence of one or more pathogens or contaminants in a sample.
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公开(公告)号：US09724691B2
公开(公告)日：2017-08-08
申请号：US15336715
申请日：2016-10-27
申请人： CUE INC.
发明人： Ayub Khattak , Clinton Sever , Paul Nelson , Ryan Cooper , Thomas Congdon , Justin Demartino , Raphael Shapiro , Mark Duncan
IPC分类号： B01L3/00 , G01N27/327 , G01N35/00 , G01N33/543
CPC分类号： B01L3/508 , B01L3/5023 , B01L3/5027 , B01L3/502715 , B01L3/502738 , B01L3/5029 , B01L3/523 , B01L2200/025 , B01L2200/027 , B01L2200/0668 , B01L2200/0684 , B01L2200/0689 , B01L2200/10 , B01L2200/14 , B01L2200/16 , B01L2300/023 , B01L2300/047 , B01L2300/0627 , B01L2300/0645 , B01L2300/0663 , B01L2300/0672 , B01L2300/069 , B01L2300/0809 , B01L2300/0816 , B01L2300/0867 , B01L2300/087 , B01L2300/1805 , B01L2300/1827 , B01L2400/0406 , B01L2400/0481 , B01L2400/0677 , C12Q1/6825 , G01N27/3273 , G01N33/54366 , G01N35/0098 , G01N35/10
摘要： Devices, systems, and methods for detecting molecules of interest within a collected sample are described herein. In certain embodiments, self-contained sample analysis systems are disclosed, which include a reusable reader component, a disposable cartridge component, and a disposable sample collection component. The reader component may communicate with a remote computing device for the digital transmission of test protocols and test results. In various disclosed embodiments, the systems, components, and methods are configured to identify the presence, absence, and/or quantity of particular nucleic acids, proteins, or other analytes of interest, for example, in order to test for the presence of one or more pathogens or contaminants in a sample.
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5.发明授权公开(公告)号：US09623409B2
公开(公告)日：2017-04-18
申请号：US15336735
申请日：2016-10-27
申请人： CUE INC.
发明人： Ayub Khattak , Clinton Sever , Paul Nelson , Ryan Cooper , Thomas Congdon , Justin Demartino , Raphael Shapiro , Mark Duncan
IPC分类号： G01N31/22 , B01L3/00 , B01L7/00 , B05D3/00 , C12Q1/68 , F16K99/00 , G01N27/28 , G01N27/327 , G01N33/543 , G01N33/58 , G01N35/00 , H04M1/725 , G01N1/02 , G01N21/78 , G01N35/10
CPC分类号： B01L3/508 , B01F11/0266 , B01L3/5027 , B01L3/502715 , B01L3/502723 , B01L3/502738 , B01L3/5029 , B01L7/52 , B01L2200/025 , B01L2200/026 , B01L2200/027 , B01L2200/028 , B01L2200/0668 , B01L2200/0684 , B01L2200/0689 , B01L2200/087 , B01L2200/10 , B01L2200/16 , B01L2300/023 , B01L2300/025 , B01L2300/04 , B01L2300/044 , B01L2300/06 , B01L2300/0627 , B01L2300/0645 , B01L2300/0681 , B01L2300/0816 , B01L2300/0838 , B01L2300/0864 , B01L2300/0867 , B01L2300/087 , B01L2300/12 , B01L2300/161 , B01L2300/1827 , B01L2400/0406 , B01L2400/0439 , B01L2400/0487 , B01L2400/0677 , B01L2400/0683 , B05D3/002 , B05D2518/00 , C12Q1/6825 , F16K99/0032 , F16K99/0036 , F16K2099/0084 , G01N1/02 , G01N21/78 , G01N27/28 , G01N27/3271 , G01N27/3272 , G01N27/3273 , G01N33/54306 , G01N33/54326 , G01N33/54333 , G01N33/54366 , G01N33/54373 , G01N33/581 , G01N35/00029 , G01N35/0098 , G01N35/1095 , G01N2001/027 , G01N2001/028 , G01N2035/00277 , G01N2035/00554 , G01N2458/30 , H04M1/72527 , Y10T137/1797
摘要： Devices, systems, and methods for detecting molecules of interest within a collected sample are described herein. In certain embodiments, self-contained sample analysis systems are disclosed, which include a reusable reader component, a disposable cartridge component, and a disposable sample collection component. The reader component may communicate with a remote computing device for the digital transmission of test protocols and test results. In various disclosed embodiments, the systems, components, and methods are configured to identify the presence, absence, and/or quantity of particular nucleic acids, proteins, or other analytes of interest, for example, in order to test for the presence of one or more pathogens or contaminants in a sample.
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6.发明申请CARTRIDGES, KITS, AND METHODS FOR ENHANCED DETECTION AND QUANTIFICATION OF ANALYTES 有权用于增强分析仪检测和量化的盒子，套件和方法公开(公告)号：US20170045507A1
公开(公告)日：2017-02-16
申请号：US15336487
申请日：2016-10-27
申请人： CUE INC.
发明人： Ayub Khattak , Clinton Sever , Paul Nelson , Ryan Cooper , Thomas Congdon , Justin Demartino , Raphael Shapiro , Mark Duncan
IPC分类号： G01N33/543
CPC分类号： B01L3/508 , B01L3/5023 , B01L3/5027 , B01L3/502715 , B01L3/502738 , B01L3/5029 , B01L3/523 , B01L2200/025 , B01L2200/027 , B01L2200/0668 , B01L2200/0684 , B01L2200/0689 , B01L2200/10 , B01L2200/14 , B01L2200/16 , B01L2300/023 , B01L2300/047 , B01L2300/0627 , B01L2300/0645 , B01L2300/0663 , B01L2300/0672 , B01L2300/069 , B01L2300/0809 , B01L2300/0816 , B01L2300/0867 , B01L2300/087 , B01L2300/1805 , B01L2300/1827 , B01L2400/0406 , B01L2400/0481 , B01L2400/0677 , C12Q1/6825 , G01N27/3273 , G01N33/54366 , G01N35/0098 , G01N35/10
摘要： Devices, systems, and methods for detecting molecules of interest within a collected sample are described herein. In certain embodiments, self-contained sample analysis systems are disclosed, which include a reusable reader component, a disposable cartridge component, and a disposable sample collection component. The reader component may communicate with a remote computing device for the digital transmission of test protocols and test results. In various disclosed embodiments, the systems, components, and methods are configured to identify the presence, absence, and/or quantity of particular nucleic acids, proteins, or other analytes of interest, for example, in order to test for the presence of one or more pathogens or contaminants in a sample.
摘要翻译： 在本文中描述了用于检测收集的样品中的感兴趣分子的装置，系统和方法。 在某些实施例中，公开了自包含的样品分析系统，其包括可重复使用的读取器部件，一次性药筒部件和一次性样品收集部件。 读取器组件可以与远程计算设备通信，用于测试协议和测试结果的数字传输。 在各种公开的实施方案中，系统，组分和方法被配置为鉴定特定核酸，蛋白质或其它感兴趣的分析物的存在，不存在和/或数量，例如为了测试一种 或更多的病原体或污染物。
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公开(公告)号：US09962703B2
公开(公告)日：2018-05-08
申请号：US15487956
申请日：2017-04-14
申请人： CUE INC.
发明人： Ayub Khattak , Clinton Sever , Paul Nelson , Ryan Cooper , Thomas Congdon , Justin Demartino , Raphael Shapiro , Mark Duncan
IPC分类号： G01N31/22 , B01L3/00 , B05D3/00 , C12Q1/68 , F16K99/00 , G01N27/28 , G01N27/327 , G01N33/543 , G01N33/58 , G01N35/00 , H04M1/725 , B01L7/00 , G01N1/02 , G01N21/78 , G01N35/10
CPC分类号： B01L3/508 , B01F11/0266 , B01L3/5027 , B01L3/502715 , B01L3/502723 , B01L3/502738 , B01L3/5029 , B01L7/52 , B01L2200/025 , B01L2200/026 , B01L2200/027 , B01L2200/028 , B01L2200/0668 , B01L2200/0684 , B01L2200/0689 , B01L2200/087 , B01L2200/10 , B01L2200/16 , B01L2300/023 , B01L2300/025 , B01L2300/04 , B01L2300/044 , B01L2300/06 , B01L2300/0627 , B01L2300/0645 , B01L2300/0681 , B01L2300/0816 , B01L2300/0838 , B01L2300/0864 , B01L2300/0867 , B01L2300/087 , B01L2300/12 , B01L2300/161 , B01L2300/1827 , B01L2400/0406 , B01L2400/0439 , B01L2400/0487 , B01L2400/0677 , B01L2400/0683 , B05D3/002 , B05D2518/00 , C12Q1/6825 , F16K99/0032 , F16K99/0036 , F16K2099/0084 , G01N1/02 , G01N21/78 , G01N27/28 , G01N27/3271 , G01N27/3272 , G01N27/3273 , G01N33/54306 , G01N33/54326 , G01N33/54333 , G01N33/54366 , G01N33/54373 , G01N33/581 , G01N35/00029 , G01N35/0098 , G01N35/1095 , G01N2001/027 , G01N2001/028 , G01N2035/00277 , G01N2035/00554 , G01N2458/30 , H04M1/72527 , Y10T137/1797
摘要： Devices, systems, and methods for detecting molecules of interest within a collected sample are described herein. In certain embodiments, self-contained sample analysis systems are disclosed, which include a reusable reader component, a disposable cartridge component, and a disposable sample collection component. The reader component may communicate with a remote computing device for the digital transmission of test protocols and test results. In various disclosed embodiments, the systems, components, and methods are configured to identify the presence, absence, and/or quantity of particular nucleic acids, proteins, or other analytes of interest, for example, in order to test for the presence of one or more pathogens or contaminants in a sample.
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公开(公告)号：US09808804B2
公开(公告)日：2017-11-07
申请号：US15336712
申请日：2016-10-27
申请人： CUE INC.
发明人： Ayub Khattak , Clinton Sever , Paul Nelson , Ryan Cooper , Thomas Congdon , Justin Demartino , Raphael Shapiro , Mark Duncan
IPC分类号： G01N21/75 , B01L3/00 , G01N27/327 , G01N35/10 , G01N35/00 , G01N33/543 , C12Q1/68
CPC分类号： B01L3/508 , B01L3/5023 , B01L3/5027 , B01L3/502715 , B01L3/502738 , B01L3/5029 , B01L3/523 , B01L2200/025 , B01L2200/027 , B01L2200/0668 , B01L2200/0684 , B01L2200/0689 , B01L2200/10 , B01L2200/14 , B01L2200/16 , B01L2300/023 , B01L2300/047 , B01L2300/0627 , B01L2300/0645 , B01L2300/0663 , B01L2300/0672 , B01L2300/069 , B01L2300/0809 , B01L2300/0816 , B01L2300/0867 , B01L2300/087 , B01L2300/1805 , B01L2300/1827 , B01L2400/0406 , B01L2400/0481 , B01L2400/0677 , C12Q1/6825 , G01N27/3273 , G01N33/54366 , G01N35/0098 , G01N35/10
摘要： Devices, systems, and methods for detecting molecules of interest within a collected sample are described herein. In certain embodiments, self-contained sample analysis systems are disclosed, which include a reusable reader component, a disposable cartridge component, and a disposable sample collection component. The reader component may communicate with a remote computing device for the digital transmission of test protocols and test results. In various disclosed embodiments, the systems, components, and methods are configured to identify the presence, absence, and/or quantity of particular nucleic acids, proteins, or other analytes of interest, for example, in order to test for the presence of one or more pathogens or contaminants in a sample.
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9.发明申请CARTRIDGES, COLLECTORS, KITS, AND METHODS FOR ENHANCED DETECTION AND QUANTIFICATION OF ANALYTES IN COLLECTED FLUID SAMPLES 有权收集器，收集器，套件和方法，用于增强收集流体样品中分析物的检测和定量公开(公告)号：US20170043335A1
公开(公告)日：2017-02-16
申请号：US15336712
申请日：2016-10-27
申请人： CUE INC.
发明人： Ayub Khattak , Clinton Sever , Paul Nelson , Ryan Cooper , Thomas Congdon , Justin Demartino , Raphael Shapiro , Mark Duncan
IPC分类号： B01L3/00
CPC分类号： B01L3/508 , B01L3/5023 , B01L3/5027 , B01L3/502715 , B01L3/502738 , B01L3/5029 , B01L3/523 , B01L2200/025 , B01L2200/027 , B01L2200/0668 , B01L2200/0684 , B01L2200/0689 , B01L2200/10 , B01L2200/14 , B01L2200/16 , B01L2300/023 , B01L2300/047 , B01L2300/0627 , B01L2300/0645 , B01L2300/0663 , B01L2300/0672 , B01L2300/069 , B01L2300/0809 , B01L2300/0816 , B01L2300/0867 , B01L2300/087 , B01L2300/1805 , B01L2300/1827 , B01L2400/0406 , B01L2400/0481 , B01L2400/0677 , C12Q1/6825 , G01N27/3273 , G01N33/54366 , G01N35/0098 , G01N35/10
摘要： Devices, systems, and methods for detecting molecules of interest within a collected sample are described herein. In certain embodiments, self-contained sample analysis systems are disclosed, which include a reusable reader component, a disposable cartridge component, and a disposable sample collection component. The reader component may communicate with a remote computing device for the digital transmission of test protocols and test results. In various disclosed embodiments, the systems, components, and methods are configured to identify the presence, absence, and/or quantity of particular nucleic acids, proteins, or other analytes of interest, for example, in order to test for the presence of one or more pathogens or contaminants in a sample.
摘要翻译： 在本文中描述了用于检测收集的样品中的感兴趣分子的装置，系统和方法。 在某些实施例中，公开了自包含的样品分析系统，其包括可重复使用的读取器部件，一次性药筒部件和一次性样品收集部件。 读取器组件可以与远程计算设备通信，用于测试协议和测试结果的数字传输。 在各种公开的实施方案中，系统，组分和方法被配置为鉴定特定核酸，蛋白质或其它感兴趣的分析物的存在，不存在和/或数量，例如为了测试一种 或更多的病原体或污染物。
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10.发明申请SYSTEMS AND METHODS FOR FACILITATING FLUID FLOW DURING ENHANCED DETECTION AND QUANTIFICATION OF ANALYTES 审中-公开在增强检测和分析数据的过程中促进流体流动的系统和方法公开(公告)号：US20170043334A1
公开(公告)日：2017-02-16
申请号：US15336502
申请日：2016-10-27
申请人： CUE INC.
发明人： Ayub Khattak , Clinton Sever , Paul Nelson , Ryan Cooper , Thomas Congdon , Justin Demartino , Raphael Shapiro , Mark Duncan
IPC分类号： B01L3/00
CPC分类号： B01L3/508 , B01L3/5023 , B01L3/5027 , B01L3/502715 , B01L3/502738 , B01L3/5029 , B01L3/523 , B01L2200/025 , B01L2200/027 , B01L2200/0668 , B01L2200/0684 , B01L2200/0689 , B01L2200/10 , B01L2200/14 , B01L2200/16 , B01L2300/023 , B01L2300/047 , B01L2300/0627 , B01L2300/0645 , B01L2300/0663 , B01L2300/0672 , B01L2300/069 , B01L2300/0809 , B01L2300/0816 , B01L2300/0867 , B01L2300/087 , B01L2300/1805 , B01L2300/1827 , B01L2400/0406 , B01L2400/0481 , B01L2400/0677 , C12Q1/6825 , G01N27/3273 , G01N33/54366 , G01N35/0098 , G01N35/10
摘要： Devices, systems, and methods for detecting molecules of interest within a collected sample are described herein. In certain embodiments, self-contained sample analysis systems are disclosed, which include a reusable reader component, a disposable cartridge component, and a disposable sample collection component. The reader component may communicate with a remote computing device for the digital transmission of test protocols and test results. In various disclosed embodiments, the systems, components, and methods are configured to identify the presence, absence, and/or quantity of particular nucleic acids, proteins, or other analytes of interest, for example, in order to test for the presence of one or more pathogens or contaminants in a sample.
摘要翻译： 在本文中描述了用于检测收集的样品中的感兴趣分子的装置，系统和方法。 在某些实施例中，公开了自包含的样品分析系统，其包括可重复使用的读取器部件，一次性药筒部件和一次性样品收集部件。 读取器组件可以与远程计算设备通信，用于测试协议和测试结果的数字传输。 在各种公开的实施方案中，系统，组分和方法被配置为鉴定特定核酸，蛋白质或其它感兴趣的分析物的存在，不存在和/或数量，例如为了测试一种 或更多的病原体或污染物。
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