-
1.Synthesis and Application of New Structural Well Defined Branched Polymers as Conjugating Agents for Peptides 审中-公开
标题翻译: 新型结构定义的支化聚合物作为多肽共轭剂的合成与应用公开(公告)号:US20090240028A1
公开(公告)日:2009-09-24
申请号:US12276885
申请日:2008-11-24
申请人: Carsten Behrens , Florencio Zaragoza Dorwald , Mikael Kofod-Hansen , Jesper Lau , Janos Tibor Kodra , Thomas Kruse Hansen , Paw Bloch
发明人: Carsten Behrens , Florencio Zaragoza Dorwald , Mikael Kofod-Hansen , Jesper Lau , Janos Tibor Kodra , Thomas Kruse Hansen , Paw Bloch
IPC分类号: C07K14/00
CPC分类号: C12P21/005 , A61K47/549 , A61K47/60 , C12N9/6437
摘要: The invention provides synthesis and application of new structural well defined branched polymers as protraction agents for peptide and protein.
摘要翻译: 本发明提供新的结构明确的支化聚合物作为肽和蛋白质的助剂的合成和应用。
-
公开(公告)号:US20130053315A1
公开(公告)日:2013-02-28
申请号:US13427791
申请日:2012-03-22
申请人: Jesper Lau , Thomas Kruse Hansen , Kjeld Madsen , Paw Bloch , Florencio Zaragoza Dorwald , Nils Langeland Johansen
发明人: Jesper Lau , Thomas Kruse Hansen , Kjeld Madsen , Paw Bloch , Florencio Zaragoza Dorwald , Nils Langeland Johansen
IPC分类号: C07K2/00 , C07C235/74 , C07C237/22 , C07D251/54 , C07D207/416 , C07D209/26 , C07D333/68 , A61K38/26 , A61P3/10 , A61P3/04 , A61P9/12 , A61P3/06 , A61P25/00 , A61P9/10 , A61P1/04 , C07C309/17
CPC分类号: C07K14/605 , A61K38/00 , A61K38/26 , A61K47/54 , A61K47/542 , A61K47/60 , C07K14/001
摘要: Novel polypeptide derivatives having protracted profile of action.
摘要翻译: 新型多肽衍生物具有延长的作用特征。
-
公开(公告)号:US20100305032A1
公开(公告)日:2010-12-02
申请号:US12774131
申请日:2010-05-05
申请人: Jesper Lau , Thomas Kruse Hansen , Kjeld Madsen , Paw Bloch , Florencio Zaragoza Dorwald , Nils Langeland Johansen
发明人: Jesper Lau , Thomas Kruse Hansen , Kjeld Madsen , Paw Bloch , Florencio Zaragoza Dorwald , Nils Langeland Johansen
IPC分类号: A61K38/26 , C07K14/605 , A61P3/10
CPC分类号: C07K14/605 , A61K38/00 , A61K38/26 , A61K47/54 , A61K47/542 , A61K47/60 , C07K14/001
摘要: Novel polypeptide derivatives having protracted profile of action.
摘要翻译: 新型多肽衍生物具有延长的作用特征。
-
公开(公告)号:US20130040884A1
公开(公告)日:2013-02-14
申请号:US13427667
申请日:2012-03-22
申请人: Jesper Lau , Thomas Kruse Hansen , Kjeld Madsen , Paw Bloch , Florencio Zaragoza Dorwald , Nils Langeland Johansen
发明人: Jesper Lau , Thomas Kruse Hansen , Kjeld Madsen , Paw Bloch , Florencio Zaragoza Dorwald , Nils Langeland Johansen
IPC分类号: C07K14/605 , C07C235/06 , C07C309/15 , C07C235/74 , C07D251/70 , C07D207/416 , C07D209/26 , C07D333/68 , C07K14/49 , C07K14/495 , C07K14/65 , C07K14/555 , C12N9/96 , C07K14/535 , C07K14/62 , C07K14/675 , C07K14/695 , C07K14/585 , C07K2/00 , A61K38/02 , A61K38/26
CPC分类号: C07K14/605 , A61K38/00 , A61K38/26 , A61K47/54 , A61K47/542 , A61K47/60 , C07K14/001
摘要: Novel polypeptide derivatives having protracted profile of action.
摘要翻译: 新型多肽衍生物具有延长的作用特征。
-
公开(公告)号:US20090156478A1
公开(公告)日:2009-06-18
申请号:US11908834
申请日:2006-03-20
申请人: Jesper Lau , Florencio Zaragoza Dorwald , Henrik Stephensen , Paw Bloch , Thomas Kruse Hansen , Kjeld Madsen
发明人: Jesper Lau , Florencio Zaragoza Dorwald , Henrik Stephensen , Paw Bloch , Thomas Kruse Hansen , Kjeld Madsen
IPC分类号: A61K38/26 , C07K14/605 , A61P3/10
CPC分类号: C07K14/605 , A61K38/00
摘要: Protracted GLP-1 compounds and therapeutic uses thereof.
摘要翻译: 延长的GLP-1化合物及其治疗用途。
-
公开(公告)号:US06881746B2
公开(公告)日:2005-04-19
申请号:US10448529
申请日:2003-05-30
申请人: Jesper Lau , Inge Thoger Christensen , Peter Madsen , Paw Bloch , Carsten Behrens , Janos Tibor Kodra , Poul Enrico Nielsen
发明人: Jesper Lau , Inge Thoger Christensen , Peter Madsen , Paw Bloch , Carsten Behrens , Janos Tibor Kodra , Poul Enrico Nielsen
IPC分类号: A61K31/195 , A61K31/198 , A61K31/41 , A61K31/4439 , A61K45/06 , A61K31/425 , A61P3/00 , C07D277/04
CPC分类号: A61K45/06 , A61K31/195 , A61K31/198 , A61K31/41 , A61K31/4439 , A61K2300/00
摘要: Novel compounds that act to antagonize the action of the glucagon peptide hormone on the glucagon receptor. More particularly, it relates to glucagon antagonists or inverse agonists.
摘要翻译: 用于拮抗胰高血糖素肽激素对胰高血糖素受体的作用的新型化合物。 更具体地,涉及胰高血糖素拮抗剂或反向激动剂。
-
7.Synthesis and application of new structural well defined branched polymers as conjugating agents for peptides 审中-公开
标题翻译: 新结构明确的支化聚合物作为肽缀合剂的合成和应用公开(公告)号:US20060182714A1
公开(公告)日:2006-08-17
申请号:US11344767
申请日:2006-02-01
申请人: Carsten Behrens , Florencio Dorwald , Mikael Kofod-Hansen , Jesper Lau , Janos Kodra , Thomas Hansen , Paw Bloch
发明人: Carsten Behrens , Florencio Dorwald , Mikael Kofod-Hansen , Jesper Lau , Janos Kodra , Thomas Hansen , Paw Bloch
CPC分类号: C12P21/005 , A61K47/549 , A61K47/60 , C12N9/6437
摘要: The invention provides synthesis and application of new structural well defined branched polymers as protraction agents for peptide and protein.
摘要翻译: 本发明提供新的结构明确的支化聚合物作为肽和蛋白质的助剂的合成和应用。
-
公开(公告)号:US07541373B2
公开(公告)日:2009-06-02
申请号:US11365534
申请日:2006-03-01
申请人: Dharma Rao Polisetti , Janos Tibor Kodra , Jesper Lau , Paw Bloch , Mustafa Guzel , Kalpathy Chidambareswaran Santhosh , Adnan M. M. Mjalli , Robert Carl Andrews , Govindan Subramanian , Michael Ankersen , Per Vedso , Anthony Murray , Lone Jeppesen , Jesper Lau
发明人: Dharma Rao Polisetti , Janos Tibor Kodra , Jesper Lau , Paw Bloch , Mustafa Guzel , Kalpathy Chidambareswaran Santhosh , Adnan M. M. Mjalli , Robert Carl Andrews , Govindan Subramanian , Michael Ankersen , Per Vedso , Anthony Murray , Lone Jeppesen , Jesper Lau
IPC分类号: A61K31/426 , C07D277/38
CPC分类号: C07D213/75 , C07D277/48 , C07D277/52 , C07D277/54 , C07D277/56 , C07D285/135 , C07D417/06 , C07D417/12 , C07D417/14 , C07D473/38
摘要: This invention relates to aryl carbonyl derivatives which are activators of glucokinase which may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial.
摘要翻译: 本发明涉及作为葡萄糖激酶活化剂的芳基羰基衍生物,其可用于治疗,治疗,控制或辅助治疗疾病,其中增加葡糖激酶活性是有益的。
-
公开(公告)号:US07897628B2
公开(公告)日:2011-03-01
申请号:US11982248
申请日:2007-10-31
申请人: Dharma Rao Polisetti , Janos Tibor Kodra , Jesper Lau , Paw Bloch , Maria Carmen Valcarce Lopez , Niels Blume , Mustafa Guzel , Kalpathy Chidambareswaran Santhosh , Adnan M.M. Mjalli , Robert Carl Andrews , Govindan Subramanian , Michael Ankersen , Per Vedso , Anthony Murray , Lone Jeppesen
发明人: Dharma Rao Polisetti , Janos Tibor Kodra , Jesper Lau , Paw Bloch , Maria Carmen Valcarce Lopez , Niels Blume , Mustafa Guzel , Kalpathy Chidambareswaran Santhosh , Adnan M.M. Mjalli , Robert Carl Andrews , Govindan Subramanian , Michael Ankersen , Per Vedso , Anthony Murray , Lone Jeppesen
IPC分类号: A61K31/426 , C07D277/46
CPC分类号: C07D277/38 , A61K31/426 , A61K31/427 , A61K31/454 , A61K31/55 , A61K45/06 , C07D213/75 , C07D277/46 , C07D277/48 , C07D277/52 , C07D277/54 , C07D277/56 , C07D285/135 , C07D417/06 , C07D417/12 , C07D417/14 , C07D473/38
摘要: This invention relates to aryl carbonyl derivatives which are activators of glucokinase which may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial.
-
公开(公告)号:US20110301158A1
公开(公告)日:2011-12-08
申请号:US13209565
申请日:2011-08-15
申请人: Dharma Rao Polisetti , Janos Tibor Kodra , Jesper Lau , Paw Bloch , Maria Carmen Valcarce-Lopez , Niels Blume , Mustafa Guzel , Kalpathy Chidambareswaran Santhosh , Adnan M.M. Mjalli , Robert Carl Andrews , Govindan Subramanian , Michael Ankersen , Per Vedso , Anthony Murray , Lone Jeppesen
发明人: Dharma Rao Polisetti , Janos Tibor Kodra , Jesper Lau , Paw Bloch , Maria Carmen Valcarce-Lopez , Niels Blume , Mustafa Guzel , Kalpathy Chidambareswaran Santhosh , Adnan M.M. Mjalli , Robert Carl Andrews , Govindan Subramanian , Michael Ankersen , Per Vedso , Anthony Murray , Lone Jeppesen
IPC分类号: A61K31/5355 , A61P3/10 , A61K31/497 , A61K31/426 , A61K31/433
CPC分类号: C07D277/38 , A61K31/426 , A61K31/427 , A61K31/454 , A61K31/55 , A61K45/06 , C07D213/75 , C07D277/46 , C07D277/48 , C07D277/52 , C07D277/54 , C07D277/56 , C07D285/135 , C07D417/06 , C07D417/12 , C07D417/14 , C07D473/38
摘要: This invention relates to aryl carbonyl derivatives which are activators of glucokinase which may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial.
摘要翻译: 本发明涉及作为葡萄糖激酶活化剂的芳基羰基衍生物,其可用于治疗,治疗,控制或辅助治疗疾病,其中增加葡糖激酶活性是有益的。
-
-
-
-
-
-
-
-
-