-
公开(公告)号:US20060084677A1
公开(公告)日:2006-04-20
申请号:US11291867
申请日:2005-11-30
申请人: Chris Broka , Woongki Kim , David Smith , Kevin McLaren
发明人: Chris Broka , Woongki Kim , David Smith , Kevin McLaren
IPC分类号: A61K31/47 , C07D215/60
CPC分类号: C07D215/36
摘要: This invention relates to compounds, which are generally anti-inflammatory and analgesic compounds, and which are represented by Formula I: wherein A is a CH2, CH(OH), C(O), C═NOR4, NR5, O, S, S(O), or S(O)2, and the other substituents are as defined in the specification; or prodrugs, individual isomers, mixtures of isomers, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds and methods for their use as therapeutic agents
摘要翻译: 本发明涉及通常为抗炎和止痛化合物的化合物,其由式I表示:其中A是CH 2,CH(OH),C(O),C- NOR 4,NR 5,O,S,S(O)或S(O)2,其它取代基如所定义 在规范中; 或前药,各异构体,异构体的混合物及其药学上可接受的盐。 本发明还涉及含有这些化合物的药物组合物及其用作治疗剂的方法
-
公开(公告)号:US07186840B2
公开(公告)日:2007-03-06
申请号:US11291867
申请日:2005-11-30
IPC分类号: C07D215/38 , C07D215/44
CPC分类号: C07D215/36
摘要: This invention relates to compounds, which are generally anti-inflammatory and analgesic compounds, and which are represented by Formula I: wherein A is a CH2, CH(OH), C(O), C═NOR4, NR5, O, S, S(O), or S(O)2, and the other substituents are as defined in the specification; or prodrugs, individual isomers, mixtures of isomers, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds and methods for their use as therapeutic agents.
摘要翻译: 本发明涉及通常为抗炎和止痛化合物的化合物,其由式I表示:其中A是CH 2,CH(OH),C(O),C- NOR 4,NR 5,O,S,S(O)或S(O)2,其它取代基如所定义 在规范中; 或前药,各异构体,异构体的混合物及其药学上可接受的盐。 本发明还涉及含有这些化合物的药物组合物及其用作治疗剂的方法。
-
公开(公告)号:US07049325B2
公开(公告)日:2006-05-23
申请号:US09925883
申请日:2001-08-07
IPC分类号: C07D215/16 , C07D215/20 , A61K31/47
CPC分类号: C07D215/36
摘要: This invention relates to compounds, which are generally anti-inflammatory and analgesic compounds, and which are represented by Formula I: wherein A is a CH2, CH(OH), C(O), C═NOR4, NR5, O, S, S(O), or S(O)2, and the other substituents are as defined in the specification; or prodrugs, individual isomers, mixtures of isomers, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds and methods for their use as therapeutic agents
-
-