摘要:
A PEGylated cyclopamine analog, preparation method, uses thereof and methods for treating proliferative diseases using the same are disclosed. The PEGylated cyclopamine analog is a compound represented by the following formula I, a compound comprising at least one group represented by the following formula I (in formula I, R is straight or branched polyethylene glycol having a molecular weight between 200 and 200,000 Dalton, L and X are linking groups), or their single enantiomers, mixture of enantiomers, mixture of diastereomers, pharmaceutically acceptable salts, solvates, or hydrates.
摘要:
A PEGylated cyclopamine analog, preparation method, uses thereof and methods for treating proliferative diseases using the same are disclosed. The PEGylated cyclopamine analog is a compound represented by the following formula I, a compound comprising at least one group represented by the following formula I (in formula I, R is straight or branched polyethylene glycol having a molecular weight between 200 and 200,000 Dalton, L and X are linking groups), or their single enantiomers, mixture of enantiomers, mixture of diastereomers, pharmaceutically acceptable salts, solvates, or hydrates.
摘要:
In one example, a device for coding video data includes a video coder configured to determine, for a depth block of a depth component of video data, a co-located texture block of a corresponding texture component, and when at least a portion of the texture block corresponds to a prediction unit of the texture component that is not intra-prediction coded: disable an inter-component Wedgelet depth modeling mode for the depth block, select an intra-prediction coding mode for the depth block other than the disabled inter-component Wedgelet depth modeling mode, and code the depth block using the selected intra-prediction coding mode.
摘要:
This disclosure is about invention of fuel cells comprising vertically free-standing graphene and carbon nanosheets in the components, and methods of making thereof. Performance enhancement effect of the fuel cell is achieved by using: an electrically conducting component whose surface is covered by vertically free-standing graphene and carbon nanosheets; and/or a catalyst supporting structure made of vertically free-standing graphene and carbon nanosheets; and/or a catalyst based on vertically free-standing graphene and carbon nanosheets. Layers of fuel cells embedded with vertically free-standing graphene and carbon nanosheets can be mechanically strengthened. Vertically free-standing graphene and carbon nanosheets embedded in the electrodes can also enhance the electrical conductivity.
摘要:
A method for manufacturing a reconstituted stone raw material by using a molten slag includes: controlling a temperature of the molten slag at 1400° C.-1500° C., and performing a cast-molding process on the molten slag; and maintaining the cast-molded slag at a temperature of 800° C.-1000° C. for 1-5 hours in a non-reducing atmosphere, and then gradually cooling the cast-molded slag to a room temperature within 2-5 hours to obtain the reconstituted stone raw material. An energy-saving and efficient method for comprehensively utilizing the blast furnace slag is provided. The produced reconstituted stone raw material has such characteristics as stable color quality, abrasion resistance, pressure resistance, strong adhesiveness, low coefficient of expansion and low shrinkage ratio.
摘要:
In an example, a process for coding video data includes determining a partitioning pattern for a block of depth values comprising assigning one or more samples of the block to a first partition and assigning one or more other samples of the block to a second partition. The process also includes determining a predicted value for at least one of the first partition and the second partition based on the determined partition pattern. The process also includes coding the at least one of the first partition and the second partition based on the predicted value.
摘要:
In one example, a device for coding video data includes a video coder configured to determine, for a depth block of a depth component of video data, a co-located texture block of a corresponding texture component, and when at least a portion of the texture block corresponds to a prediction unit of the texture component that is not intra-prediction coded: disable an inter-component Wedgelet depth modeling mode for the depth block, select an intra-prediction coding mode for the depth block other than the disabled inter-component Wedgelet depth modeling mode, and code the depth block using the selected intra-prediction coding mode.
摘要:
In general, in one aspect, a graphene film is used as a protective layer for current collectors in electrochemical energy conversion and storage devices. The graphene film inhibits passivation or corrosion of the underlying metals of the current collectors without adding additional weight or volume to the devices. The graphene film is highly conductive so the coated current collectors maintain conductivity as high as that of underlying metals. The protective nature of the graphene film enables less corrosion resistant, less costly and/or lighter weight metals to be utilized as current collectors. The graphene film may be formed directly on Cu or Ni current collectors using chemical vapor deposition (CVD) or may be transferred to other types of current collectors after formation. The graphene film coated current collectors may be utilized in batteries, super capacitors, dye-sensitized solar cells, and fuel and electrolytic cells.