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公开(公告)号:US20140335564A1
公开(公告)日:2014-11-13
申请号:US14258994
申请日:2014-04-22
申请人: Chung-Ming Hsieh , Margaret Hugunin , Anwar Murtaza , Bradford L. McRae , Yuliya Kutskova , John E. Memmott , Jennifer M. Perez , Suju Zhong , Edit Tarcsa , Anca Clabbers , Craig Wallace , Shaughn H. Bryant , Mary R. Leddy
发明人: Chung-Ming Hsieh , Margaret Hugunin , Anwar Murtaza , Bradford L. McRae , Yuliya Kutskova , John E. Memmott , Jennifer M. Perez , Suju Zhong , Edit Tarcsa , Anca Clabbers , Craig Wallace , Shaughn H. Bryant , Mary R. Leddy
IPC分类号: C07K16/24
CPC分类号: C07K16/468 , A61K39/3955 , A61K2039/505 , A61K2039/507 , A61K2300/00 , C07K16/241 , C07K16/244 , C07K2317/21 , C07K2317/31 , C07K2317/50 , C07K2317/565 , C07K2317/64 , C07K2317/76 , C07K2317/92 , Y02A50/386 , Y02A50/41 , Y02A50/412 , Y02A50/466
摘要: Proteins that bind IL-17 and/or IL-17F are described along with there use in composition and methods for treating, preventing, and diagnosing IL-17 related diseases and for detecting IL-17 in cells, tissues, samples, and compositions.
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公开(公告)号:US20140343267A1
公开(公告)日:2014-11-20
申请号:US14261257
申请日:2014-04-24
申请人: Chung-Ming Hsieh , Margaret Hugunin , Anwar Murtaza , Bradford L. McRae , Yuliya Kutskova , John E. Memmott , Jennifer M. Perez , Suju Zhong , Edit Tarcsa , Anca Clabbers , Craig Wallace , Shaughn H. Bryant , Mary R. Leddy
发明人: Chung-Ming Hsieh , Margaret Hugunin , Anwar Murtaza , Bradford L. McRae , Yuliya Kutskova , John E. Memmott , Jennifer M. Perez , Suju Zhong , Edit Tarcsa , Anca Clabbers , Craig Wallace , Shaughn H. Bryant , Mary R. Leddy
CPC分类号: C07K16/468 , A61K39/3955 , A61K2039/505 , A61K2039/507 , A61K2300/00 , C07K16/241 , C07K16/244 , C07K2317/21 , C07K2317/31 , C07K2317/50 , C07K2317/565 , C07K2317/64 , C07K2317/76 , C07K2317/92 , Y02A50/386 , Y02A50/41 , Y02A50/412 , Y02A50/466
摘要: Proteins that bind IL-17 and/or IL-17F are described along with there use in composition and methods for treating, preventing, and diagnosing IL-17 related diseases and for detecting IL-17 in cells, tissues, samples, and compositions.
摘要翻译: 与用于治疗,预防和诊断IL-17相关疾病和用于检测细胞,组织,样品和组合物中的IL-17的组合物和方法一起描述了结合IL-17和/或IL-17F的蛋白质。
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公开(公告)号:US20140348834A1
公开(公告)日:2014-11-27
申请号:US14260197
申请日:2014-04-23
申请人: Chung-Ming Hsieh , Margaret Hugunin , Anwar Murtaza , Bradford L. McRae , Yuliya Kutskova , John E. Memmott , Jennifer M. Perez , Suju Zhong , Edit Tarcsa , Anca Clabbers , Craig Wallace , Shaughn H. Bryant , Mary R. Leddy
发明人: Chung-Ming Hsieh , Margaret Hugunin , Anwar Murtaza , Bradford L. McRae , Yuliya Kutskova , John E. Memmott , Jennifer M. Perez , Suju Zhong , Edit Tarcsa , Anca Clabbers , Craig Wallace , Shaughn H. Bryant , Mary R. Leddy
IPC分类号: C07K16/24 , C07K16/46 , A61K39/395
CPC分类号: C07K16/468 , A61K39/3955 , A61K2039/505 , A61K2039/507 , A61K2300/00 , C07K16/241 , C07K16/244 , C07K2317/21 , C07K2317/31 , C07K2317/50 , C07K2317/565 , C07K2317/64 , C07K2317/76 , C07K2317/92 , Y02A50/386 , Y02A50/41 , Y02A50/412 , Y02A50/466
摘要: Proteins that bind IL-17 and/or IL-17F are described along with their use in composition and methods for treating, preventing, and diagnosing IL-17 related diseases and for detecting IL-17 in cells, tissues, samples, and compositions.
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公开(公告)号:US20140017246A1
公开(公告)日:2014-01-16
申请号:US13959648
申请日:2013-08-05
申请人: Chung-Ming Hsieh , Margaret Hugunin , Anwar Murtaza , Bradford L. McRae , Yuliya Kutskova , John E. Memmott , Jennifer M. Perez , Suju Zhong , Edit Tarcsa , Anca Clabbers , Craig Wallace , Shaughn H. Bryant , Mary R. Leddy
发明人: Chung-Ming Hsieh , Margaret Hugunin , Anwar Murtaza , Bradford L. McRae , Yuliya Kutskova , John E. Memmott , Jennifer M. Perez , Suju Zhong , Edit Tarcsa , Anca Clabbers , Craig Wallace , Shaughn H. Bryant , Mary R. Leddy
IPC分类号: C07K16/24
CPC分类号: C07K16/468 , A61K39/3955 , A61K2039/505 , A61K2039/507 , A61K2300/00 , C07K16/241 , C07K16/244 , C07K2317/21 , C07K2317/31 , C07K2317/50 , C07K2317/565 , C07K2317/64 , C07K2317/76 , C07K2317/92 , Y02A50/386 , Y02A50/41 , Y02A50/412 , Y02A50/466
摘要: Proteins that bind IL-17 and/or IL-17F are described along with there use in composition and methods for treating, preventing, and diagnosing IL-17 related diseases and for detecting IL-17 in cells, tissues, samples, and compositions.
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公开(公告)号:US20140356909A1
公开(公告)日:2014-12-04
申请号:US14263724
申请日:2014-04-28
申请人: Chung-Ming Hsieh , Margaret Hugunin , Anwar Murtaza , Bradford L. McRae , Yuliya Kutskova , John E. Memmott , Jennifer M. Perez , Suju Zhong , Edit Tarcsa , Anca Clabbers , Craig Wallace , Shaughn H. Bryant , Mary R. Leddy
发明人: Chung-Ming Hsieh , Margaret Hugunin , Anwar Murtaza , Bradford L. McRae , Yuliya Kutskova , John E. Memmott , Jennifer M. Perez , Suju Zhong , Edit Tarcsa , Anca Clabbers , Craig Wallace , Shaughn H. Bryant , Mary R. Leddy
CPC分类号: C07K16/468 , A61K39/3955 , A61K2039/505 , A61K2039/507 , A61K2300/00 , C07K16/241 , C07K16/244 , C07K2317/21 , C07K2317/31 , C07K2317/50 , C07K2317/565 , C07K2317/64 , C07K2317/76 , C07K2317/92 , Y02A50/386 , Y02A50/41 , Y02A50/412 , Y02A50/466
摘要: Proteins that bind IL-17 and/or IL-17F are described along with their use in composition and methods for treating, preventing, and diagnosing IL-17 related diseases and for detecting IL-17 in cells, tissues, samples, and compositions.
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公开(公告)号:US08779101B2
公开(公告)日:2014-07-15
申请号:US13959648
申请日:2013-08-05
申请人: Chung-Ming Hsieh , Margaret Hugunin , Anwar Murtaza , Bradford L. McRae , Yuliya Kutskova , John E. Memmott , Jennifer M. Perez , Suju Zhong , Edit Tarcsa , Anca Clabbers , Craig Wallace , Shaughn H. Bryant , Mary R. Leddy
发明人: Chung-Ming Hsieh , Margaret Hugunin , Anwar Murtaza , Bradford L. McRae , Yuliya Kutskova , John E. Memmott , Jennifer M. Perez , Suju Zhong , Edit Tarcsa , Anca Clabbers , Craig Wallace , Shaughn H. Bryant , Mary R. Leddy
IPC分类号: A61K39/00
CPC分类号: C07K16/468 , A61K39/3955 , A61K2039/505 , A61K2039/507 , A61K2300/00 , C07K16/241 , C07K16/244 , C07K2317/21 , C07K2317/31 , C07K2317/50 , C07K2317/565 , C07K2317/64 , C07K2317/76 , C07K2317/92 , Y02A50/386 , Y02A50/41 , Y02A50/412 , Y02A50/466
摘要: Proteins that bind IL-17 and/or IL-17F are described along with there use in composition and methods for treating, preventing, and diagnosing IL-17 related diseases and for detecting IL-17 in cells, tissues, samples, and compositions.
摘要翻译: 与用于治疗,预防和诊断IL-17相关疾病和用于检测细胞,组织,样品和组合物中的IL-17的组合物和方法一起描述了结合IL-17和/或IL-17F的蛋白质。
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公开(公告)号:US20140348856A1
公开(公告)日:2014-11-27
申请号:US14262653
申请日:2014-04-25
申请人: Chung-Ming Hsieh , Margaret Hugunin , Anwar Murtaza , Bradford L. McRae , Yuliya Kutskova , John E. Memmott , Jennifer M. Perez , Suju Zhong , Edit Tarcsa , Anca Clabbers , Craig Wallace , Shaughn H. Bryant , Mary R. Leddy
发明人: Chung-Ming Hsieh , Margaret Hugunin , Anwar Murtaza , Bradford L. McRae , Yuliya Kutskova , John E. Memmott , Jennifer M. Perez , Suju Zhong , Edit Tarcsa , Anca Clabbers , Craig Wallace , Shaughn H. Bryant , Mary R. Leddy
IPC分类号: C07K16/24
CPC分类号: C07K16/468 , A61K39/3955 , A61K2039/505 , A61K2039/507 , A61K2300/00 , C07K16/241 , C07K16/244 , C07K2317/21 , C07K2317/31 , C07K2317/50 , C07K2317/565 , C07K2317/64 , C07K2317/76 , C07K2317/92 , Y02A50/386 , Y02A50/41 , Y02A50/412 , Y02A50/466
摘要: Proteins that bind IL-17 and/or IL-17F are described along with their use in composition and methods for treating, preventing, and diagnosing IL-17 related diseases and for detecting IL-17 in cells, tissues, samples, and compositions.
摘要翻译: 描述了结合IL-17和/或IL-17F的蛋白质及其在用于治疗,预防和诊断IL-17相关疾病和用于检测细胞,组织,样品和组合物中的IL-17的组合物和方法中的用途。
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公开(公告)号:US08835610B2
公开(公告)日:2014-09-16
申请号:US12718841
申请日:2010-03-05
申请人: Chung-Ming Hsieh , Margaret Hugunin , Yuliya Kutskova , John E. Memmott , Jennifer M. Perez , Suju Zhong , Edit Tarcsa , Anca Clabbers
发明人: Chung-Ming Hsieh , Margaret Hugunin , Yuliya Kutskova , John E. Memmott , Jennifer M. Perez , Suju Zhong , Edit Tarcsa , Anca Clabbers
IPC分类号: A61K39/395 , C07K16/24
CPC分类号: C07K16/468 , A61K39/3955 , A61K2039/505 , A61K2039/507 , A61K2300/00 , C07K16/241 , C07K16/244 , C07K2317/21 , C07K2317/31 , C07K2317/50 , C07K2317/565 , C07K2317/64 , C07K2317/76 , C07K2317/92 , Y02A50/386 , Y02A50/41 , Y02A50/412 , Y02A50/466
摘要: Proteins that bind IL-17 and/or IL-17F are described along with their use in compositions and methods for treating, preventing, and diagnosing IL-17 related diseases and for detecting IL-17 in cells, tissues, samples, and compositions.
摘要翻译: 描述了结合IL-17和/或IL-17F的蛋白质及其在用于治疗,预防和诊断IL-17相关疾病和用于检测细胞,组织,样品和组合物中的IL-17的组合物和方法中的用途。
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公开(公告)号:US20130164256A1
公开(公告)日:2013-06-27
申请号:US13659658
申请日:2012-10-24
申请人: Chung-Ming Hsieh , Tariq Ghayur , Lorenzo Benatuil , Yuliya Kutskova , John Memmott , Jennifer Perez , Suju Zhong , Carrie Goodreau , Anca Clabbers
发明人: Chung-Ming Hsieh , Tariq Ghayur , Lorenzo Benatuil , Yuliya Kutskova , John Memmott , Jennifer Perez , Suju Zhong , Carrie Goodreau , Anca Clabbers
CPC分类号: C07K16/241 , A61K39/3955 , A61K45/06 , A61K47/6847 , C07K16/464 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/565 , C07K2317/567 , C07K2317/622 , C07K2317/64 , C07K2317/76 , C07K2317/92 , G01N33/6863
摘要: Isolated binding proteins, e.g., antibodies or antigen binding portions thereof, which bind to tumor necrosis factor-alpha (TNF-α), e.g., human TNF-α, and related antibody-based compositions and molecules are disclosed. Also disclosed are pharmaceutical compositions comprising the antibodies, as well as therapeutic and diagnostic methods for using the antibodies.
摘要翻译: 公开了结合肿瘤坏死因子-α(TNF-α),例如人TNF-α和相关的基于抗体的组合物和分子的分离的结合蛋白,例如抗体或其抗原结合部分。 还公开了包含抗体的药物组合物,以及使用抗体的治疗和诊断方法。
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公开(公告)号:US20140161804A1
公开(公告)日:2014-06-12
申请号:US13659666
申请日:2012-10-24
申请人: Carolyn Cuff , Jennifer Perez , Suju Zhong , Lucia Eaton , Anca Clabbers , Christine Grinnel , Edit Tarsca , Dora Forkas , Suzanne Mathieu
发明人: Carolyn Cuff , Jennifer Perez , Suju Zhong , Lucia Eaton , Anca Clabbers , Christine Grinnel , Edit Tarsca , Dora Forkas , Suzanne Mathieu
IPC分类号: A61K39/395 , A61K45/06 , G01N33/53 , C07K16/24
CPC分类号: A61K39/3955 , A61K45/06 , A61K2039/505 , C07K16/241 , C07K16/244 , C07K16/468 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/565 , C07K2317/567 , C07K2317/622 , C07K2317/64 , C07K2317/76 , C07K2317/92 , C07K2317/94 , G01N33/5308
摘要: Engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease are provided.
摘要翻译: 提供了工程化的多价和多特异性结合蛋白,制备方法,特别是其在预防,诊断和/或治疗疾病中的用途。
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