公开(公告)号：US10184891B2

公开(公告)日：2019-01-22

申请号：US13976596

申请日：2011-12-28

申请人： Claude Weisbuch ,  Lucio Martinelli ,  Henri Benisty ,  Christof Schafauer ,  Gabriel Sagarzazu ,  Thierry Gacoin ,  Mélanie Bedu

发明人： Claude Weisbuch ,  Lucio Martinelli ,  Henri Benisty ,  Christof Schafauer ,  Gabriel Sagarzazu ,  Thierry Gacoin ,  Mélanie Bedu

IPC分类号： G01N21/77 ,  G01N21/64 ,  G01N21/47 ,  G01N21/55

摘要： A biochip device comprising a substrate constituted by at least one plate of material forming a multimode planar waveguide and carrying chromophore elements suitable for emitting fluorescence in response to excitation by guided waves having an evanescent portion, the device being characterized in that it includes coupling means for coupling excitation light with the waveguide in the form of guided waves, the coupling means being substantially non-directional.

公开(公告)号：US20140017128A1

公开(公告)日：2014-01-16

申请号：US13976596

申请日：2011-12-28

申请人： Claude Weisbuch ,  Lucio Martinelli ,  Henri Benisty ,  Thierry Gacoin ,  Christof Schafauer ,  Gabriel Sagarzazu ,  Mélanie Bedu

发明人： Claude Weisbuch ,  Lucio Martinelli ,  Henri Benisty ,  Thierry Gacoin ,  Christof Schafauer ,  Gabriel Sagarzazu ,  Mélanie Bedu

IPC分类号： G01N21/64

CPC分类号： G01N21/6428 ,  G01N21/47 ,  G01N21/6456 ,  G01N21/648 ,  G01N21/7703

摘要： A biochip device comprising a substrate constituted by at least one plate of material forming a multimode planar waveguide and carrying chromophore elements suitable for emitting fluorescence in response to excitation by guided waves having an evanescent portion, the device being characterized in that it includes coupling means for coupling excitation light with the waveguide in the form of guided waves, the coupling means being substantially non-directional.

摘要翻译： 一种生物芯片装置，包括由形成多模平面波导的至少一种材料板构成的基板，并且载体适于响应于具有ev逝部分的导波的激发而发射荧光的发色团元件，该装置的特征在于，其包括用于 将激发光与导波形式的波导耦合，耦合装置基本上是无方向的。

公开(公告)号：US20130230906A1

公开(公告)日：2013-09-05

申请号：US13885507

申请日：2011-11-16

申请人： Lucio Martinelli ,  Marc Artigue ,  Yann Marcy ,  Christof Schafauer

发明人： Lucio Martinelli ,  Marc Artigue ,  Yann Marcy ,  Christof Schafauer

IPC分类号： G01N1/28

CPC分类号： G01N1/28 ,  B01L3/502738 ,  B01L2300/0636 ,  B01L2300/0816 ,  B01L2400/0655

摘要： A cartridge for carrying out a method of analyzing the nucleic acids contained in a sample, includes a main body (1) produced in a substrate, in which there are formed at least one reaction chamber (6) and one detection chamber (10) for at least one nucleic acid likely to be contained in the sample, a microfluid circuit including a sample-injection member (7), elements (4 and 13) for respectively injecting fluids into and removing fluids from the cartridge, cavities, fluidic passages (2) and valves capable of closing them. The cartridge further includes (a) a first face known as the actuation face (16), from which the valves of the cartridge are actuated, and (b) a second face, opposite to the actuating face, including the detection chamber (10) for at least one nucleic acid likely to be contained in the sample, this face being known as the detection face (15).

摘要翻译： 用于进行分析样品中所含的核酸的方法的盒包括在基板中制造的主体（1），其中形成有至少一个反应室（6）和一个检测室（10），用于 至少一种可能包含在样品中的核酸，包括样品注射构件（7）的微流体回路，用于分别将流体输入和移出流体的元件（4和13），空腔，流体通道（2） ）和能够关闭它们的阀。 该盒还包括（a）被称为致动面（16）的第一面，盒的阀被致动，和（b）与致动面相对的第二面，包括检测室（10） 对于可能包含在样品中的至少一种核酸，该面被称为检测面（15）。