公开(公告)号：US20100157300A1

公开(公告)日：2010-06-24

申请号：US12503755

申请日：2009-07-15

申请人： Dae-Sik Lee ,  Yo-Han Choi ,  Hyun-Woo Song ,  Moon-Youn Jung ,  Seon-Hee Park ,  Gun-Yong Sung

发明人： Dae-Sik Lee ,  Yo-Han Choi ,  Hyun-Woo Song ,  Moon-Youn Jung ,  Seon-Hee Park ,  Gun-Yong Sung

IPC分类号： G01J3/46

CPC分类号： G01N21/253 ,  G01N21/8483 ,  G01N2201/0256 ,  G01N2201/0826

摘要： Provided is a liquid sample analysis chip reading system. The reading system includes an analysis chip, a light emitting part, a plurality of light wave-guides, and a light receiving part. The analysis chip includes a plurality of detecting parts. The light emitting part includes three light sources emitting light having wavelengths (or colors) different from each other. The plurality of light wave-guides irradiate the light emitted from the light emitting part onto the plurality of corresponding detecting parts, respectively. The light receiving part includes a plurality of light receiving devices for receiving the light having a specific color reflected from each of the plurality of corresponding detecting parts of the analysis chip. The three light sources are discontinuously controlled to emit light onto the plurality of light wave-guides.

摘要翻译： 提供了一种液体样品分析芯片读取系统。 读取系统包括分析芯片，发光部分，多个光波导和光接收部分。 分析芯片包括多个检测部分。 发光部分包括发射具有彼此不同的波长（或颜色）的光的三个光源。 多个光波导将从发光部发射的光分别照射到多个相应的检测部上。 光接收部分包括多个光接收装置，用于接收从分析芯片的多个相应的检测部分中的每一个反射的具有特定颜色的光。 不连续地控制三个光源以将光发射到多个光波导上。

公开(公告)号：US20100248352A1

公开(公告)日：2010-09-30

申请号：US12746559

申请日：2008-05-09

申请人： Hyun-Woo Song ,  Hyeon-Bong Pyo ,  Yo-Han Choi

发明人： Hyun-Woo Song ,  Hyeon-Bong Pyo ,  Yo-Han Choi

IPC分类号： C12M1/34 ,  G01B9/02 ,  G01N21/00

CPC分类号： G01N33/54373 ,  G01N21/77 ,  G01N2021/7776 ,  G01N2021/7779

摘要： Provided is a sensor for biological detection. The sensor for biological detection includes: a sensing unit including a light generator, an optical coupler, and an optical detector, the optical coupler dividing light incident from the light generator to project divided lights into a bio chip and a reference unit, respectively, and coupling the lights reflected from the respective bio chip and reference unit as one output light, and the optical detector detecting the output light, and the bio chip is independently separated from the sensing unit to be disposed on paths of lights divided by the optical coupler. The sensing unit has a composition of the Michelson interferometer.

摘要翻译： 提供了用于生物检测的传感器。 用于生物检测的传感器包括：感测单元，包括光发生器，光耦合器和光学检测器，光耦合器分离从光发生器入射的光以将分光投影到生物芯片和参考单元中;以及 将从各个生物芯片和参考单元反射的光耦合为一个输出光，并且光学检测器检测输出光，并且生物芯片独立地与感测单元分离，以被布置在由光耦合器分开的光的路径上。 感测单元具有迈克尔逊干涉仪的组成。

公开(公告)号：US08288171B2

公开(公告)日：2012-10-16

申请号：US12484806

申请日：2009-06-15

申请人： Hyun-Woo Song ,  Yo Han Choi ,  Hyeon-Bong Pyo

发明人： Hyun-Woo Song ,  Yo Han Choi ,  Hyeon-Bong Pyo

IPC分类号： G01N33/566

CPC分类号： G01N33/553 ,  G01N33/54393 ,  Y10T428/31507 ,  Y10T428/31678 ,  Y10T428/31681 ,  Y10T428/31692

摘要： Provided is a biochip and an apparatus for detecting a biomaterial. The biochip includes a metal thin film on the surface of a substrate, restraining autofluorescence of the substrate, and a spacer on the metal thin film, having capture molecules immobilized on the surface of the spacer and specifically bound to target molecules. The spacer has a thickness controlled to enhance the strength of a fluorescence signal emitted from a fluorophore labeled with the target molecules and immobilized on the spacer by the specific binding between the capture molecule and the target molecule.

摘要翻译： 提供了一种生物芯片和用于检测生物材料的装置。 生物芯片包括在基板表面上的金属薄膜，抑制基板的自发荧光和金属薄膜上的间隔物，其中捕获分子固定在间隔物的表面上并且特异性地结合到靶分子上。 间隔物具有被控制的厚度，以增强从用靶分子标记的荧光团发射的荧光信号的强度，并通过捕获分子和靶分子之间的特异性结合固定在间隔基上。