公开(公告)号：US07323623B2

公开(公告)日：2008-01-29

申请号：US11093088

申请日：2005-03-29

申请人： Daniel J. Altier ,  Rafael Herrmann ,  Albert L. Lu ,  Billy F. McCutchen ,  James K. Presnail ,  Janine L. Weaver ,  James F. H. Wong

发明人： Daniel J. Altier ,  Rafael Herrmann ,  Albert L. Lu ,  Billy F. McCutchen ,  James K. Presnail ,  Janine L. Weaver ,  James F. H. Wong

IPC分类号： A01H5/00 ,  A01H5/10 ,  C12N15/82 ,  C12N15/12

CPC分类号： C12N15/8282 ,  C07K14/43563 ,  Y10S530/858

摘要： The present invention is directed to nucleic acid molecules tat encode defensive polypeptides and methods of their use in enhancing disease resistance of a plant to a fungal pathogen. Vectors, expression cassettes, viruses, cells, and plants comprising a nucleotide sequence of the invention are farther provided.

摘要翻译： 本发明涉及编码防御性多肽的核酸分子及其用于增强植物对真菌病原体的抗病性的方法。 提供了包含本发明的核苷酸序列的载体，表达盒，病毒，细胞和植物。

公开(公告)号：US07064183B2

公开(公告)日：2006-06-20

申请号：US11092430

申请日：2005-03-29

申请人： Daniel J. Altier ,  Rafael Herrmann ,  Albert L. Lu ,  Billy F. McCutchen ,  James K. Presnail ,  Janine L. Weaver ,  James F. H. Wong

发明人： Daniel J. Altier ,  Rafael Herrmann ,  Albert L. Lu ,  Billy F. McCutchen ,  James K. Presnail ,  Janine L. Weaver ,  James F. H. Wong

IPC分类号： C07K1/00

CPC分类号： C12N15/8282 ,  C07K14/43563 ,  Y10S530/858

摘要： The methods and compositions of the present invention find use in impacting microbial pathogens and in enhancing disease resistance to pathogens, particularly by plants. The compositions of the invention include polypeptides that possess antimicrobial properties, particularly fungicidal properties, and the encoding nucleic acid molecules. The polypeptides of the invention are isolated from the hemolymph and fat bodies of insect larvae induced by injection of plant pathogenic fungi. Further provided are plant cells, plants, and seed thereof, transformed with the nucleic acid molecules of the invention so as to confer disease resistance on the plant.

摘要翻译： 本发明的方法和组合物用于影响微生物病原体并增强对病原体的抗病性，特别是植物的抗病性。 本发明的组合物包括具有抗微生物特性，特别是杀真菌性质和编码核酸分子的多肽。 通过注射植物致病真菌诱导的昆虫幼虫的血淋巴和脂肪体分离本发明的多肽。 进一步提供了用本发明的核酸分子转化的植物细胞，植物和种子，以赋予植物抗病性。

公开(公告)号：US07202214B2

公开(公告)日：2007-04-10

申请号：US11092429

申请日：2005-03-29

申请人： Daniel J. Altier ,  Rafael Herrmann ,  Albert L. Lu ,  Billy F. McCutchen ,  James K. Presnail ,  Janine L. Weaver ,  James F. H. Wong

发明人： Daniel J. Altier ,  Rafael Herrmann ,  Albert L. Lu ,  Billy F. McCutchen ,  James K. Presnail ,  Janine L. Weaver ,  James F. H. Wong

IPC分类号： A61K38/17 ,  C07K14/435

CPC分类号： C12N15/8282 ,  C07K14/43563 ,  Y10S530/858

摘要： The methods and compositions of the present invention find use in impacting microbial pathogens and in enhancing disease resistance to pathogens, particularly by plants. The compositions of the invention include polypeptides that possess antimicrobial properties, particularly fungicidal properties, and the encoding nucleic acid molecules. The polypeptides of the invention are isolated from the hemolymph and fat bodies of insect larvae induced by injection of plant pathogenic fungi. Further provided are plant cells, plants, and seed thereof, transformed with the nucleic acid molecules of the invention so as to confer disease resistance on the plant.

摘要翻译： 本发明的方法和组合物用于影响微生物病原体并增强对病原体的抗病性，特别是植物的抗病性。 本发明的组合物包括具有抗微生物特性，特别是杀真菌性质和编码核酸分子的多肽。 通过注射植物致病真菌诱导的昆虫幼虫的血淋巴和脂肪体分离本发明的多肽。 进一步提供了用本发明的核酸分子转化的植物细胞，植物和种子，以赋予植物抗病性。

公开(公告)号：US06891085B2

公开(公告)日：2005-05-10

申请号：US10125258

申请日：2002-04-18

申请人： Daniel J. Altier ,  Rafael Herrmann ,  Albert L. Lu ,  Billy F. McCutchen ,  James K. Presnail ,  Janine L. Weaver ,  James F. H. Wong

发明人： Daniel J. Altier ,  Rafael Herrmann ,  Albert L. Lu ,  Billy F. McCutchen ,  James K. Presnail ,  Janine L. Weaver ,  James F. H. Wong

IPC分类号： C07K14/435 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N7/01 ,  C12N15/12 ,  C12N15/82 ,  A10H5/00 ,  C12N15/11 ,  C12N15/63 ,  A10H5/10

CPC分类号： C12N15/8282 ,  C07K14/43563 ,  Y10S530/858

摘要： The methods and compositions of the present invention find use in impacting microbial pathogens and in enhancing disease resistance to pathogens, particularly by plants. The compositions of the invention include nucleic acid molecules encoding Fus6 polypeptides derived from Agrotis ipsilon that possess antimicrobial properties, particularly fungicidal properties. Further provided are plant cells plants, and seed thereof, transformed with the nucleic acid molecules of the invention so as to confer disease resistance on the plant.

摘要翻译： 本发明的方法和组合物用于影响微生物病原体并增强对病原体的抗病性，特别是植物的抗病性。 本发明的组合物包括编码具有抗微生物性质，特别是杀真菌性质的源自Agrotis ipsilon的Fus6多肽的核酸分子。 还提供了用本发明的核酸分子转化的植物细胞植物及其种子，以赋予植物抗病性。

公开(公告)号：US07262342B2

公开(公告)日：2007-08-28

申请号：US11092027

申请日：2005-03-29

申请人： Daniel J. Altier ,  Rafael Herrmann ,  Albert L. Lu ,  Billy F. McCutchen ,  James K. Presnail ,  Janine L. Weaver ,  James F. H. Wong

发明人： Daniel J. Altier ,  Rafael Herrmann ,  Albert L. Lu ,  Billy F. McCutchen ,  James K. Presnail ,  Janine L. Weaver ,  James F. H. Wong

IPC分类号： A01H5/00 ,  A01H5/10 ,  C12N15/82 ,  C12N15/12

CPC分类号： C12N15/8282 ,  C07K14/43563 ,  Y10S530/858

摘要： The present invention is directed to nucleic acid molecules that encode Fus6 defensive polypeptides and methods of their use in enhancing disease resistance of a plant to a fungal pathogen. Vectors, expression cassettes, viruses, cells, and plants comprising a nucleotide sequence of the invention are further provided.

摘要翻译： 本发明涉及编码Fus6防御多肽的核酸分子及其用于增强植物对真菌病原体的抗病性的方法。 进一步提供载体，表达盒，病毒，细胞和包含本发明的核苷酸序列的植物。

公开(公告)号：US07064184B2

公开(公告)日：2006-06-20

申请号：US11093225

申请日：2005-03-29

申请人： Daniel J. Altier ,  Rafael Herrmann ,  Albert L. Lu ,  Billy F. McCutchen ,  James K. Presnail ,  Janine L. Weaver ,  James F.H. Wong

发明人： Daniel J. Altier ,  Rafael Herrmann ,  Albert L. Lu ,  Billy F. McCutchen ,  James K. Presnail ,  Janine L. Weaver ,  James F.H. Wong

IPC分类号： C07K14/00 ,  C07K1/00

CPC分类号： C12N15/8282 ,  C07K14/43563 ,  Y10S530/858

摘要： The methods and compositions of the present invention find use in impacting microbial pathogens and in enhancing disease resistance to pathogens, particularly by plants. The compositions of the invention include polypeptides that possess antimicrobial properties, particularly fungicidal properties, and the encoding nucleic acid molecules. The polypeptides of the invention are isolated from the hemolymph and fat bodies of insect larvae induced by injection of plant pathogenic fungi. Further provided are plant cells, plants, and seed thereof, transformed with the nucleic acid molecules of the invention so as to confer disease resistance on the plant.

摘要翻译： 本发明的方法和组合物用于影响微生物病原体并增强对病原体的抗病性，特别是植物的抗病性。 本发明的组合物包括具有抗微生物特性，特别是杀真菌性质和编码核酸分子的多肽。 通过注射植物致病真菌诱导的昆虫幼虫的血淋巴和脂肪体分离本发明的多肽。 进一步提供了用本发明的核酸分子转化的植物细胞，植物和种子，以赋予植物抗病性。