公开(公告)号：US06927382B2

公开(公告)日：2005-08-09

申请号：US10153243

申请日：2002-05-22

申请人： David Andrew King ,  Richard J. Pittaro ,  Shahida Rana ,  Edward Verdonk ,  Frederick A. Stawitcke ,  Richard D. Pering

发明人： David Andrew King ,  Richard J. Pittaro ,  Shahida Rana ,  Edward Verdonk ,  Frederick A. Stawitcke ,  Richard D. Pering

IPC分类号： H01L21/98 ,  H01L25/16 ,  H01L27/146 ,  H01L31/00 ,  H01L31/12

CPC分类号： H01L24/95 ,  H01L25/167 ,  H01L25/50 ,  H01L27/14683 ,  H01L31/125 ,  H01L2224/95085 ,  H01L2924/01013 ,  H01L2924/01015 ,  H01L2924/01027 ,  H01L2924/01033 ,  H01L2924/01049 ,  H01L2924/10158 ,  H01L2924/12041 ,  H01L2924/12042 ,  H01L2924/12043 ,  H01L2924/00

摘要： The disclosure is directed toward an optical excitation/detection device that includes an arrayed plurality of photodetectors and separately formed photoemitters, as well as a method for making such a device. A CMOS fabricated photodetector array including a plurality of individual photoreceptors is selectively etched back between photoreceptor locations to reveal a plurality of recessed regions having a certain geographic profile. A plurality of semiconductor blocks, each having light emitting capability and each having a certain geometric profile that is complementary in size and shape to the certain geometric profile of the recessed regions, are separately fabricated. These blocks are included within a fluid to form a slurry. The slurry is then flowed over the CMOS fabricated photodetector array in accordance with a fluidic self-assembly technique, and the included semiconductor blocks are individually deposited within each of the plurality of recessed regions in the CMOS fabricated photodetector array. The deposited blocks are then attached within the recessed regions to form the optical excitation/detection device from an arrayed plurality of photodetectors and separately formed photoemitters.

摘要翻译： 本公开涉及一种光激励/检测装置，其包括阵列的多个光电检测器和单独形成的光电发生器，以及用于制造这种装置的方法。 包括多个单独光感受器的CMOS制造的光检测器阵列被选择性地在感光体位置之间回蚀刻以露出具有一定地理轮廓的多个凹陷区域。 分别制造多个半导体块，每个半导体块具有发光能力，并且各自具有与凹陷区域的某些几何轮廓尺寸和形状互补的一定几何轮廓。 这些块被包含在流体中以形成浆料。 然后根据流体自组装技术将浆料流过CMOS制造的光电检测器阵列，并且将所包含的半导体块分别沉积在CMOS制造的光电检测器阵列中的多个凹陷区域的每一个内。 然后将沉积的块附接在凹陷区域内，以从阵列的多个光电检测器和单独形成的光电发生器形成光学激发/检测装置。

公开(公告)号：US06821793B2

公开(公告)日：2004-11-23

申请号：US10668435

申请日：2003-09-22

申请人： Edward Verdonk ,  Richard J. Pittaro ,  Shahida Rana ,  David Andrew King ,  Frederick A. Stawitcke ,  Richard D. Pering

发明人： Edward Verdonk ,  Richard J. Pittaro ,  Shahida Rana ,  David Andrew King ,  Frederick A. Stawitcke ,  Richard D. Pering

IPC分类号： H01L2100

CPC分类号： H01L27/14643 ,  H01L25/0753 ,  H01L25/167 ,  H01L2924/0002 ,  H01L2924/00

摘要： The disclosure is directed toward an optical excitation/detection device that includes an arrayed plurality of photodetectors and discrete photoemitters, as well as a method for making such a device. A CMOS fabricated photodetector array includes an arrayed plurality of photoreceptor areas and photoemitter areas, wherein each photoreceptor area includes a CMOS integrated photoreceptor and each photoemitter area includes at least two buried electric contact pads. The CMOS array is selectively etched back at the locations of the photoemitter areas for regions to reveal the buried contact pads. A plurality of discrete semiconductor photoemitter devices (such as, for example, light emitting diodes) are inserted into, and mechanically retained within, the regions of the CMOS fabricated photodetector array. The inserted discrete semiconductor photoemitter devices make electrical contact with the buried electric contact pads that are revealed within each of the regions to form the optical excitation/detection device from an arrayed plurality of photodetectors and discrete semiconductor photoemitters.

摘要翻译： 本公开涉及包括阵列的多个光电探测器和分立光电发生器的光学激发/检测装置，以及用于制造这种装置的方法。 CMOS制造的光电检测器阵列包括阵列的多个感光体区域和光电发射器区域，其中每个感光体区域包括CMOS集成感光体，并且每个光电发射器区域包括至少两个埋入的电接触焊盘。 CMOS阵列在光电探测器区域的位置处被选择性地回蚀，用于区域以露出埋入的接触焊盘。 多个分立的半导体光电探测器装置（例如，发光二极管）被插入并机械地保持在CMOS制造的光电检测器阵列的区域内。 插入的分立半导体光电发生器装置与在每个区域内露出的掩埋电接触焊盘电接触，以从阵列的多个光电探测器和分立的半导体光电发生器形成光激发/检测装置。

公开(公告)号：US06657235B1

公开(公告)日：2003-12-02

申请号：US10153760

申请日：2002-05-22

申请人： Edward Verdonk ,  Richard J. Pittaro ,  Shahida Rana ,  David Andrew King ,  Frederick A. Stawitcke ,  Richard D. Pering

发明人： Edward Verdonk ,  Richard J. Pittaro ,  Shahida Rana ,  David Andrew King ,  Frederick A. Stawitcke ,  Richard D. Pering

IPC分类号： H01L2926

CPC分类号： H01L27/14643 ,  H01L25/0753 ,  H01L25/167 ,  H01L2924/0002 ,  H01L2924/00

摘要： The disclosure is directed toward an optical excitation/detection device that includes an arrayed plurality of photodetectors and discrete photoemitters, as well as a method for making such a device. A CMOS fabricated photodetector array includes an arrayed plurality of photoreceptor areas and photoemitter areas, wherein each photoreceptor area includes a CMOS integrated photoreceptor and each photoemitter area includes at least two buried electric contact pads. The CMOS array is selectively etched back at the locations of the photoemitter areas for regions to reveal the buried contact pads. A plurality of discrete semiconductor photoemitter devices (such as, for example, light emitting diodes) are inserted into, and mechanically retained within, the regions of the CMOS fabricated photodetector array. The inserted discrete semiconductor photoemitter devices make electrical contact with the buried electric contact pads that are revealed within each of the regions to form the optical excitation/detection device from an arrayed plurality of photodetectors and discrete semiconductor photoemitters.

摘要翻译： 本公开涉及包括阵列的多个光电探测器和分立光电发生器的光学激发/检测装置，以及用于制造这种装置的方法。 CMOS制造的光电检测器阵列包括阵列的多个感光体区域和光电发射器区域，其中每个感光体区域包括CMOS集成感光体，并且每个光电发射器区域包括至少两个埋入的电接触焊盘。 CMOS阵列在光电探测器区域的位置处被选择性地回蚀，用于区域以露出埋入的接触焊盘。 多个分立的半导体光电探测器装置（例如，发光二极管）被插入并机械地保持在CMOS制造的光电检测器阵列的区域内。 插入的分立半导体光电发生器装置与在每个区域内露出的掩埋电接触焊盘电接触，以从阵列的多个光电探测器和分立的半导体光电发生器形成光激发/检测装置。

公开(公告)号：US06640197B2

公开(公告)日：2003-10-28

申请号：US10072240

申请日：2002-02-08

申请人： Richard J. Pittaro ,  David Andrew King ,  Richard D. Pering ,  Shahida Rana ,  Frederick A. Stawitcke ,  Edward Verdonk

发明人： Richard J. Pittaro ,  David Andrew King ,  Richard D. Pering ,  Shahida Rana ,  Frederick A. Stawitcke ,  Edward Verdonk

IPC分类号： G01C2500

CPC分类号： G01N21/253

摘要： A sensor array is bonded to or molded together with a micro-lens array to form a sensor cartridge. The micro-lenses of the micro-lens array are configured to focus light incident on the sensors, into the sensors. An alignment structure has a mating profile that receives and engages one or more micro-lenses from the micro-lens array to laterally align the cartridge to enable repeatable precise positioning of the cartridge.

摘要翻译： 传感器阵列与微透镜阵列结合或模制在一起以形成传感器盒。 微透镜阵列的微透镜被配置为将入射到传感器上的光聚焦到传感器中。 对准结构具有匹配轮廓，该配合轮廓接收并接合来自微透镜阵列的一个或多个微透镜以横向对准盒，以使得盒的可重复的精确定位。

公开(公告)号：US06642498B2

公开(公告)日：2003-11-04

申请号：US09990609

申请日：2001-11-21

申请人： Edward Verdonk ,  David A. King ,  Richard D. Pering ,  Richard J. Pittaro ,  Shahida Rana ,  Frederick A. Stawitcke

发明人： Edward Verdonk ,  David A. King ,  Richard D. Pering ,  Richard J. Pittaro ,  Shahida Rana ,  Frederick A. Stawitcke

IPC分类号： G01J142

CPC分类号： G01N21/6452 ,  G01N21/645 ,  G01N2021/6463 ,  G01N2021/6482

摘要： The present invention is directed to a micromirror optical multiplexer for directing light to an array of sensors. The micromirror optical multiplexer directs light from one or more sources onto multiple, coplanar sensors for the purpose of exciting fluorescence. The micromirror optical multiplexer includes at least one light source and a micromirror array having a top face and up to four side faces. Pivotable mirrors of the micromirror array are arranged in a multiple row, multiple column format on the top face. In addition, each of the side faces of the micromirror array has at least one row of pivotable mirrors. By pivoting one side face mirror and one top face mirror, a light source entering at one corner of the micromirror array can be directed to exit near normal incidence anywhere on the bottom of the device.

摘要翻译： 本发明涉及一种用于将光引导到传感器阵列的微镜光学多路复用器。 微镜光复用器将来自一个或多个源的光引导到多个共面传感器上，以激发荧光。 微镜光复用器包括至少一个光源和具有顶面和多达四个侧面的微镜阵列。 微镜阵列的透视镜在顶面以多列，多列格式排列。 此外，微镜阵列的每个侧面具有至少一排可枢转镜。 通过枢转一个侧面反射镜和一个顶面反射镜，进入微镜阵列的一个角落处的光源可被引导到设备底部的任何地方的正常入射附近。

公开(公告)号：US06707958B2

公开(公告)日：2004-03-16

申请号：US09988468

申请日：2001-11-20

申请人： Richard D. Pering ,  David A. King ,  Richard J. Pittaro ,  Shahida Rana ,  Frederick A. Stawitcke ,  Edward D. Verdonk

发明人： Richard D. Pering ,  David A. King ,  Richard J. Pittaro ,  Shahida Rana ,  Frederick A. Stawitcke ,  Edward D. Verdonk

IPC分类号： G02B600

CPC分类号： G01N21/552 ,  B01L3/5085 ,  G01N35/028

摘要： A biochemical assay device optically scans individual biological sample containing wells in an assay plate. The device includes an imaging system overlaying the assay plate wherein a scanning light propagates by total internal reflection within an optical waveguide. The waveguide includes a plurality of pixel locations, each aligned with a well in the assay plate, at which total internal reflection is selectively frustrated to output an incident beam of light. That light illuminates the well and causes generation of an emission beam of light that is detected by a photoreceptor. The device further includes a driver circuit that controls the selective frustration of total internal reflection at each pixel location in order to scan each well in the assay plate. A processor is also included in the device to process the detected emission beams of light generated by the scanned wells for purposes of assaying the biological sample contained in each scanned well.

摘要翻译： 生物化学测定装置在测定板中光学扫描含有孔的各种生物样品。 该装置包括覆盖测定板的成像系统，其中扫描光通过光波导内的全内反射传播。 波导包括多个像素位置，每个像素位置与测定板中的阱对准，在该位置处，全内反射被选择性地挫败以输出入射光束。 该光照射井，并产生由感光体检测到的发射光束。 该装置还包括驱动器电路，其控制每个像素位置处的全内反射的选择性挫败，以扫描测定板中的每个孔。 为了分析每个扫描井中包含的生物样品的目的，处理器还包括在该装置中以处理由扫描井产生的检测到的发射光束。

公开(公告)号：US20100040903A1

公开(公告)日：2010-02-18

申请号：US12192075

申请日：2008-08-14

申请人： Andrew S. Kalt ,  Marvin Keshner ,  Donald Winston Rice ,  Frederick A. Stawitcke ,  Jessie Ramirez Sanchez

发明人： Andrew S. Kalt ,  Marvin Keshner ,  Donald Winston Rice ,  Frederick A. Stawitcke ,  Jessie Ramirez Sanchez

IPC分类号： B32B15/01 ,  B23K20/10

CPC分类号： B23K20/106 ,  B23K20/002 ,  H01L24/78 ,  H01L2224/45014 ,  H01L2224/78 ,  H01L2924/00014 ,  H01L2924/01029 ,  Y10T428/12493 ,  H01L2224/48 ,  H01L2224/45015 ,  H01L2924/207 ,  H01L2924/206

摘要： A horn for vibratory solid-state ultrasonic welding of metals and similarly-behaved materials “self-levels” to produce wide continuous seams or large-area spot-welds between delicate workpieces without damage, even if the workpieces are not perfectly flat and parallel to the nominal toolface angle. The horn toolface flexes under pressure to conform to skew-angled workpieces because it is disposed on a tool head supported by a tool neck cut from the tool body. The tool head, the tool neck, or both are anisotropically compliant. When resonances are properly optimized for typical VSS modes of vibration, atypical but useful localized modes are excited at the compliant toolface edges, actually intensifying the bond energy where one might normally expect unwanted damping. Various design approaches optimize the characteristics of the tool head and tool neck to various materials and bonding configurations. The horns can be configured for use with existing ultrasonic welders.

摘要翻译： 用于金属和类似行为的材料的振动固态超声波焊接的喇叭用于“自我级别”，以在不损坏的工件之间产生宽阔的连续接缝或大面积点焊，即使工件不是完全平坦且平行 标称工具面角度。 喇叭工具表面在压力下弯曲以符合斜角工件，因为它设置在由从工具主体切割的工具颈部支撑的工具头上。 工具头，工具颈部或两者都是各向异性的。 当对于典型的VSS振动模式适当地优化谐振时，非标准但有用的局部模式在兼容的工具面边缘处被激发，实际上增强了通常可能期望不希望的阻尼的结合能。 各种设计方法将刀头和刀颈的特性优化到各种材料和接合结构。 喇叭可以配置用于现有的超声波焊接机。

公开(公告)号：US4448192A

公开(公告)日：1984-05-15

申请号：US354993

申请日：1982-03-05

申请人： Frederick A. Stawitcke ,  William J. Mordan ,  Holly B. Jimison ,  Robert Piziali ,  Allen K. Ream

发明人： Frederick A. Stawitcke ,  William J. Mordan ,  Holly B. Jimison ,  Robert Piziali ,  Allen K. Ream

IPC分类号： A61M16/00 ,  A61M16/20

CPC分类号： A61M16/0051 ,  A61M16/00 ,  A61M16/0009 ,  A61M16/204 ,  A61M16/205 ,  A61M16/208 ,  A61M2230/46

摘要： A ventilator which accommodates to a patient's efforts in breathing and to his change in respiratory requirements is provided by a system with a novel control law. The novel control law determines a target ideal pressure-volume wave-form which characterizes the patient's respiratory requirements; this waveform is constantly modified and corrected during the course of ventilator operation to enable the patient to breathe with minimum ventilation opposition, or fighting.

摘要翻译： 适应患者呼吸努力及呼吸需求变化的呼吸机由具有新颖控制规律的系统提供。 新颖的控制规律确定了特征患者呼吸要求的目标理想压力 - 体积波形; 在呼吸机操作过程中，这种波形不断地被修改和纠正，以使患者能够以最小的通气反对力或者战斗呼吸。

公开(公告)号：US5056992A

公开(公告)日：1991-10-15

申请号：US314322

申请日：1989-02-22

申请人： Tad D. Simons ,  Frederick A. Stawitcke ,  William M. Reed ,  Paul A. Tessier ,  Marc J. Zeitlin

发明人： Tad D. Simons ,  Frederick A. Stawitcke ,  William M. Reed ,  Paul A. Tessier ,  Marc J. Zeitlin

IPC分类号： A61M5/142 ,  F04B43/02

CPC分类号： F04B43/02 ,  A61M5/14224 ,  F04B43/021

摘要： An apparatus and method are disclosed for an IV pump which can act also as a passive infusion controller. The apparatus has a disposable flow chamber with two pumping subchambers connected by a first collapsible passageway. A pump drive is used to operate the pumping subchambers and includes a first control valve for depressing the first collapsible passageway to control flow between the subchambers and an outlet control valve for depressing an outlet collapsible passageway to control flow of infusate out of the flow chamber. The flow chamber has a base surface and first and second caps, each cap being spaced apart from the base surface and having means for attachment to one of two moveable connector rods. The caps each act as one side of the first and second pumping subchambers, respectively, the base surface being the other side. A flexible wall is connected to the base surface and to each of the caps providing the subchamber volumes therebetween. The flexible wall is constructed of a material having a thickness and modulus of elasticity such that when the connector rods are not moving the flexible wall element does not collapse when subjected to a negative gauge pressure.

摘要翻译： 公开了用于IV泵的装置和方法，其也可以用作无源输液控制器。 该设备具有一次性流动室，其中两个泵送子室通过第一可折叠通道连接。 泵驱动器用于操作泵送子室，并且包括用于按压第一可折叠通道以控制子室之间的流动的第一控制阀和用于按压出口可折叠通道的出口控制阀，以控制流出流出室的输注物流。 流动室具有基座表面和第一和第二盖，每个盖子与基座表面间隔开并且具有用于附接到两个可移动连接杆之一的装置。 盖子分别作为第一和第二抽吸子室的一侧，基座表面是另一侧。 柔性壁连接到基座表面和每个盖上，以提供其间的子室体积。 柔性壁由具有厚度和弹性模量的材料构成，使得当连接器杆不移动时，当承受负表压时，柔性壁元件不会塌陷。

公开(公告)号：US4857048A

公开(公告)日：1989-08-15

申请号：US173021

申请日：1988-03-21

申请人： Tad D. Simons ,  Frederick A. Stawitcke ,  William M. Reed ,  Paul A. Tessier

发明人： Tad D. Simons ,  Frederick A. Stawitcke ,  William M. Reed ,  Paul A. Tessier

IPC分类号： A61M5/142 ,  F04B43/02

CPC分类号： A61M5/14224 ,  F04B43/02 ,  F04B43/021

摘要： An apparatus and method are disclosed for an IV pump which can act also as a passive infusion controller. The apparatus has a disposable flow chamber with two pumping subchambers connected by a first collapsible passageway. A pump drive is used to operate the pumping subchambers and includes a first control valve for depressing the first collapsible passageway to control flow between the subchambers and an outlet control valve for depressing an outlet collapsible passageway to control flow of infusate out of the flow chamber. The flow chamber has a base surface and first and second caps, each cap being spaced apart from the base surface and having means for attachment to one of two moveable connector rods. The caps each act as one side of the first and second pumping subchambers, respectively, the base surface being the other side. A flexible wall is connected to the base surface and to each of the caps providing the subchamber volumes therebetween. The flexible wall is constructed of a material having a thickness and modulus of elasticity such that when the connector rods are not moving the flexible wall element does not collapse when subjected to a negative gauge pressure.

摘要翻译： 公开了用于IV泵的装置和方法，其也可以用作无源输液控制器。 该设备具有一次性流动室，其中两个泵送子室通过第一可折叠通道连接。 泵驱动器用于操作泵送子室，并且包括用于按压第一可折叠通道以控制子室之间的流动的第一控制阀和用于按压出口可折叠通道的出口控制阀，以控制流出流出室的输注物流。 流动室具有基座表面和第一和第二盖，每个盖子与基座表面间隔开并且具有用于附接到两个可移动连接杆之一的装置。 盖子分别作为第一和第二抽吸子室的一侧，基座表面是另一侧。 柔性壁连接到基座表面和每个盖上，以提供其间的子室体积。 柔性壁由具有厚度和弹性模量的材料构成，使得当连接器杆不移动时，当承受负表压时，柔性壁元件不会塌陷。