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公开(公告)号:US5538739A
公开(公告)日:1996-07-23
申请号:US643880
申请日:1991-01-18
申请人: David Bodmer , Jones W. Fong , Thomas Kissel , Hawkins V. Maulding, Jr. , Oskar Nagele , Jane E. Pearson
发明人: David Bodmer , Jones W. Fong , Thomas Kissel , Hawkins V. Maulding, Jr. , Oskar Nagele , Jane E. Pearson
CPC分类号: A61K38/31 , A61K9/1647 , A61K9/5031 , C08G63/08
摘要: The invention discloses microparticles comprising a polypeptide, preferably somatostatin or an analog or derivative thereof, more preferably octreotide, in a polymeric matrix, preferably poly(lactide-co-glycolide) glucose. The invention also discloses sustained release formulations containing said microparticles and the use of said formulations in treating acromegaly and breast cancer.
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公开(公告)号:US5688530A
公开(公告)日:1997-11-18
申请号:US470909
申请日:1995-06-06
申请人: David Bodmer , Jones W. Fong , Thomas Kissel , Hawkins V. Maulding , Oskar Nagele , Jane E. Pearson
发明人: David Bodmer , Jones W. Fong , Thomas Kissel , Hawkins V. Maulding , Oskar Nagele , Jane E. Pearson
CPC分类号: A61K38/31 , A61K9/1647 , A61K9/5031 , C08G63/08
摘要: The invention discloses microparticles comprising a polypeptide, preferably somatostatin or an analog or derivative thereof, more preferably octreotide, in a polymeric matrix, preferably poly(lactide-co-glycolide) glucose. The invention also discloses sustained release formulations containing said microparticles and the use of said formulations in treating acromegaly and breast cancer.
摘要翻译: 本发明公开了在聚合物基质,优选聚(丙交酯 - 共 - 乙交酯)葡萄糖中包含多肽,优选生长抑素或其类似物或衍生物,更优选奥曲肽的微粒。 本发明还公开了含有所述微粒的缓释制剂和所述制剂在治疗肢端肥大症和乳腺癌中的用途。
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公开(公告)号:US5639480A
公开(公告)日:1997-06-17
申请号:US470072
申请日:1995-06-06
申请人: David Bodmer , Jones W. Fong , Thomas Kissel , Hawkins V. Maulding , Oskar Nagele , Jane E. Pearson
发明人: David Bodmer , Jones W. Fong , Thomas Kissel , Hawkins V. Maulding , Oskar Nagele , Jane E. Pearson
CPC分类号: A61K9/1647 , A61K38/31 , A61K9/5031
摘要: The invention discloses microparticles comprising a polypeptide, preferably somatostatin or an analog or derivative thereof, more preferably octreotide, in a polymeric matrix, preferably poly(lactide-co-glycolide)glucose. The invention also discloses sustained release formulations containing said microparticles and the use of said formulations in treating acromegaly and breast cancer.
摘要翻译: 本发明公开了在聚合物基质,优选聚(丙交酯 - 共 - 乙交酯)葡萄糖中包含多肽,优选生长抑素或其类似物或衍生物,更优选奥曲肽的微粒。 本发明还公开了含有所述微粒的缓释制剂和所述制剂在治疗肢端肥大症和乳腺癌中的用途。
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公开(公告)号:US5876761A
公开(公告)日:1999-03-02
申请号:US470907
申请日:1995-06-06
申请人: David Bodmer , Jones W. Fong , Thomas Kissel , Hawkins V. Maulding , Oskar Nagele , Jane E. Pearson
发明人: David Bodmer , Jones W. Fong , Thomas Kissel , Hawkins V. Maulding , Oskar Nagele , Jane E. Pearson
CPC分类号: A61K9/1647 , A61K38/31 , A61K9/5031
摘要: The invention discloses microparticles comprising a polypeptide, preferably somatostatin or an analog or derivative thereof, more preferably octreotide, in a polymeric matrix, preferably poly(lactide-co-glycolide) glucose. The invention also discloses sustained release formulations containing said microparticles and the use of said formulations in treating acromegaly and breast cancer.
摘要翻译: 本发明公开了在聚合物基质,优选聚(丙交酯 - 共 - 乙交酯)葡萄糖中包含多肽,优选生长抑素或其类似物或衍生物,更优选奥曲肽的微粒。 本发明还公开了含有所述微粒的缓释制剂和所述制剂在治疗肢端肥大症和乳腺癌中的用途。
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