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    Controlled release dosage form including a banded engine
    4.
    发明申请
    Controlled release dosage form including a banded engine 审中-公开
    受控释放剂型，包括带状发动机

    公开(公告)号：US20050186273A1

    公开(公告)日：2005-08-25

    申请号：US10950039

    申请日：2004-09-24

    申请人： Si-Hong Yum ,  Crystal Pollock-Dove ,  Liang-Chang Dong ,  Patrick Wong

    发明人： Si-Hong Yum ,  Crystal Pollock-Dove ,  Liang-Chang Dong ,  Patrick Wong

    IPC分类号： A61K9/00 ,  A61K9/20 ,  A61K9/22

    CPC分类号： A61K9/0004

    摘要： The present invention includes a dosage form configured to provide the controlled release of an active agent formulation. A dosage form according to the present invention includes a reservoir containing an active agent formulation and an engine positioned at least partially within the reservoir. In order to reduce the possibility that the engine included in a dosage form of the present invention will separate from the reservoir either during or after fabrication, the dosage form of the present invention includes a band that binds the engine to the reservoir. The band is provided over an outside surface of the both the engine and the reservoir at or near the interface formed where the engine enters the opening provided in the reservoir. The present invention also includes a method of fabricating controlled release dosage forms having banded engine.

    摘要翻译： 本发明包括配制成提供活性剂制剂的受控释放的剂型。 根据本发明的剂型包括含有活性剂制剂的储存器和至少部分地位于储存器内的发动机。 为了减少包含在本发明的剂型中的发动机在制造期间或之后与储存器分离的可能性，本发明的剂型包括将发动机结合到储存器的带。 该带被设置在发动机进入设置在储存器中的开口所形成的界面处或附近的发动机和储存器两侧的外表面上。 本发明还包括制造具有带状发动机的控释剂型的方法。

    Drug delivery device with minimal residual drug retention
    5.
    发明授权
    Drug delivery device with minimal residual drug retention 失效
    具有最小残留药物保留率的药物输送装置

    公开(公告)号：US5902605A

    公开(公告)日：1999-05-11

    申请号：US851525

    申请日：1997-04-18

    申请人： Liang C. Dong ,  Patrick S.-L. Wong ,  Si-Hong Yum ,  Crystal Pollock

    发明人： Liang C. Dong ,  Patrick S.-L. Wong ,  Si-Hong Yum ,  Crystal Pollock

    IPC分类号： A61K9/00 ,  A61K9/22

    CPC分类号： A61K9/0004

    摘要： The present invention is directed to a fluid-imbibing drug delivery device which is useful for the initial delayed delivery of an active agent formulation to a fluid environment of use, the initial delay period to startup or activation of the device being of a predetermined length of time. The delivery of the agent formulation from the dispensing device is continued until essentially all of the active agent formulation is delivered as a result of the fluid inhibition into a fluid flow path in the housing of the device and the expansion of an expansion agent in the active agent delivery chamber.

    摘要翻译： 本发明涉及一种流体吸收药物递送装置，其可用于将活性剂制剂初始延迟递送至使用的流体环境，初始延迟时间为启动或启动装置的预定长度 时间。 药剂制剂从分配装置的输送继续进行，直到基本上所有的活性剂制剂由于液体抑制被输送到装置的壳体中的流体流动路径和活性物质中膨胀剂的膨胀而被递送 代理商送货室。