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公开(公告)号:US08183245B2
公开(公告)日:2012-05-22
申请号:US12682612
申请日:2008-10-21
申请人: David J. Guerin , Joos Jung , Elizabeth Stanton
发明人: David J. Guerin , Joos Jung , Elizabeth Stanton
IPC分类号: A61K31/4965
CPC分类号: C07D471/04
摘要: The present invention relates to pyrazine substituted pyrrolopyridines having formula (I) useful as inhibitors of JAK kinases (JAK1, JAK2, JAK3 and/or TYK2) and/or PDK1 and for the treatment of myeloproliferative disorders or other cancers.
摘要翻译: 本发明涉及可用作JAK激酶(JAK1,JAK2,JAK3和/或TYK2)和/或PDK1的抑制剂和用于治疗骨髓增生性疾病或其它癌症的式(I)的吡嗪取代的吡咯并吡啶。