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    BLOOD ACESS APPARATUS AND METHOD
    2.
    发明申请
    BLOOD ACESS APPARATUS AND METHOD 审中-公开
    血液消融装置及方法

    公开(公告)号：US20080306580A1

    公开(公告)日：2008-12-11

    申请号：US12025350

    申请日：2008-02-04

    申请人： Mark L. Jenson ,  William J. Drasler ,  Jason P. Hill ,  Jaydeep Kokate ,  David J. Sogard ,  Pat Haverkost

    发明人： Mark L. Jenson ,  William J. Drasler ,  Jason P. Hill ,  Jaydeep Kokate ,  David J. Sogard ,  Pat Haverkost

    IPC分类号： A61F2/82 ,  A61F2/84 ,  A61B17/32 ,  B23P11/00

    CPC分类号： A61M1/3655 ,  A61F2/07 ,  A61F2/82 ,  A61F2/90 ,  A61F2002/072 ,  A61F2002/075 ,  Y10T29/49826

    摘要： A blood access for dialysis includes a radially distensible support structure having an open lattice structure defining a support wall having interstitial open areas and defining exterior and luminal wall surfaces; a first porous polymeric portion having a plurality of pores, the first porous polymeric portion being securably disposed over at least a portion of the exterior wall portion of the support structure; a second porous polymeric portion having a plurality of pores, the second porous polymeric portion being securably disposed over at least a portion of the luminal portion of the support structure; and a biodegradable and/or bioabsorbable material disposed within the pores of the first polymeric portion and/or pores of the second polymeric portion.

    摘要翻译： 用于透析的血液通道包括径向扩张的支撑结构，其具有限定具有间隙开放区域并限定外部和腔壁表面的支撑壁的开放格子结构; 具有多个孔的第一多孔聚合物部分，所述第一多孔聚合物部分可固定地设置在所述支撑结构的外壁部分的至少一部分上; 具有多个孔的第二多孔聚合物部分，所述第二多孔聚合物部分可固定地设置在所述支撑结构的腔部分的至少一部分上; 以及设置在第二聚合物部分的第一聚合物部分的孔内和/或第二聚合物部分的孔内的可生物降解和/或生物可吸收材料。

    FIBROUS CONTAINMENT FOR HEMOSTASIS PLUG
    4.
    发明申请
    FIBROUS CONTAINMENT FOR HEMOSTASIS PLUG 审中-公开
    用于HEMOSTASIS PLUG的FIBROUS容纳

    公开(公告)号：US20120101525A1

    公开(公告)日：2012-04-26

    申请号：US13278910

    申请日：2011-10-21

    申请人： Mark L. Jenson ,  Jason P. Hill ,  James Q. Feng ,  David J. Sogard ,  Robert W. Warner ,  Patrick A. Haverkost

    发明人： Mark L. Jenson ,  Jason P. Hill ,  James Q. Feng ,  David J. Sogard ,  Robert W. Warner ,  Patrick A. Haverkost

    IPC分类号： A61B17/04

    CPC分类号： A61B17/0057 ,  A61B2017/00637 ,  A61B2017/00654 ,  A61B2017/00659 ,  A61B2017/0404 ,  A61B2017/0417 ,  A61B2017/06185

    摘要： A device for sealing an opening in a vessel includes an anchor attached to a suture. The anchor is inserted through the opening into the vessel, and the suture pulls the anchor against the vessel wall, forming a seal. A plug is inserted over the suture and is axially compressed toward the anchor, locking the elements in place. The suture is braided or woven outside of the anchor so that it may be stored and handled easily, and is unbraided, unwoven and/or untangled at its distal end inside the anchor, so that individual filaments within the suture may extend laterally within the anchor. The laterally extending filaments subtend a larger footprint within the anchor than a comparable footprint if the suture were to remain braided or tied into a knot within the anchor, which may more effectively distribute the retaining forces within the anchor.

    摘要翻译： 用于密封容器中的开口的装置包括附接到缝合线的锚固件。 锚固件通过开口插入容器中，并且缝合线将锚固件拉靠在血管壁上，形成密封。 将塞子插入缝合线上并朝向锚固件轴向压缩，将元件锁定就位。 该缝合线被编织或编织在锚定体之外，使得其可以容易地储存和处理，并且在其锚固体内部的远端处是未被覆盖的，无纺的和/或解开的，使得缝合线内的单个细丝可以在锚定件内横向延伸 。 横向延伸的长丝在锚固体内对着较大的覆盖区域，而不是如果缝合线保持编织或连接到锚固体内的结，这可以更有效地将锚定力分配在锚固体内。

    Minimally Invasive Access for Renal Nerve Ablation
    6.
    发明申请
    Minimally Invasive Access for Renal Nerve Ablation 有权
    微创获取肾神经消融

    公开(公告)号：US20120123303A1

    公开(公告)日：2012-05-17

    申请号：US13243134

    申请日：2011-09-23

    申请人： David Sogard ,  Scott Smith ,  Mark L. Jenson

    发明人： David Sogard ,  Scott Smith ,  Mark L. Jenson

    IPC分类号： A61B18/18 ,  A61B18/04 ,  A61N7/00 ,  A61B18/00

    CPC分类号： A61B18/1492 ,  A61B90/37 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B2018/0212 ,  A61N5/062 ,  A61N7/022 ,  A61N2005/067 ,  A61N2007/003

    摘要： An elongated flexible medical device is inserted into a patient's body via a natural orifice, and advanced through the natural orifice to a location proximate innervated tissue that influences renal sympathetic nerve activity. The medical device can be advanced into a body organ and to a location within the organ proximate the innervated tissue. The organ may comprise an organ of the gastrointestinal tract or urinary tract. The medical device may be advanced through and beyond an access hole in a wall of the organ, and situated at a location proximate the innervated tissue. One or both of imaging and ablation energy is delivered from a distal end of the medical device to the innervated tissue. Innervated renal tissue can be ablated using various forms of energy, including RF energy, ultrasound energy, optical energy, and thermal energy.

    摘要翻译： 细长的柔性医疗装置通过自然孔插入患者体内，并通过自然孔推进到影响肾交感神经活动的靠近神经组织的位置。 医疗装置可以进入身体器官和靠近神经组织的器官内的位置。 器官可以包括胃肠道或泌尿道的器官。 医疗装置可以前进穿过器官壁中的进入孔并且位于邻近神经组织的位置处。 成像和消融能量中的一个或两个从医疗装置的远端传送到神经组织。 可以使用各种形式的能量消融内源性肾组织，包括射频能量，超声能量，光能和热能。

    PRECISION ELECTRODE MOVEMENT CONTROL FOR RENAL NERVE ABLATION
    7.
    发明申请
    PRECISION ELECTRODE MOVEMENT CONTROL FOR RENAL NERVE ABLATION 有权
    精神电极运动控制用于神经退行性疾病

    公开(公告)号：US20120029513A1

    公开(公告)日：2012-02-02

    申请号：US13194920

    申请日：2011-07-30

    申请人： Scott Smith ,  Leonard B. Richardson ,  Mark L. Jenson

    发明人： Scott Smith ,  Leonard B. Richardson ,  Mark L. Jenson

    IPC分类号： A61B18/14

    CPC分类号： A61B18/1492 ,  A61B18/1815 ,  A61B18/20 ,  A61B90/39 ,  A61B2018/00011 ,  A61B2018/00434 ,  A61B2018/00577 ,  A61B2018/00589 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61M25/0054 ,  A61M25/0113 ,  A61M25/0127 ,  A61M25/0138 ,  A61M25/0147

    摘要： A catheter is configured to access a renal artery. A lumen of the catheter's shaft is dimensioned to receive a flexible actuation member which extends between the shaft's proximal and distal ends. The actuation member is moveable within the lumen and subject to elastic deformation, friction, and/or whip along its length. A flexible support member is coupled to a distal end of the actuation member and extendible beyond a distal tip of the shaft. An RF ablation electrode at a distal end of the support member is configured to ablated perivascular renal nerve tissue. A position converter at the distal end of the shaft is configured to convert movement of the actuation member into one or both of controlled rotational and axial movement of the support member and electrode to one of a multiplicity of stable circumferential positions substantially free of elastic deformation, friction, and/or whip impacting actuation member movement.

    摘要翻译： 导管配置成进入肾动脉。 导管轴的内腔的尺寸被设计成容纳在轴的近端和远端之间延伸的柔性致动构件。 致动构件可在内腔内移动并且沿其长度受到弹性变形，摩擦和/或鞭状。 柔性支撑构件联接到致动构件的远端并且可延伸超过轴的远侧末端。 在支撑构件的远端处的RF消融电极被配置为消融血管周围肾神经组织。 在轴的远端处的位置转换器被配置为将致动构件的运动转换成支撑构件和电极的受控旋转和轴向运动到基本上没有弹性变形的多个稳定的圆周位置中的一个或两个， 摩擦和/或搅动撞击致动构件运动。

    Precision electrode movement control for renal nerve ablation
    8.
    发明授权
    Precision electrode movement control for renal nerve ablation 有权
    精神电极移动控制肾神经消融

    公开(公告)号：US09358365B2

    公开(公告)日：2016-06-07

    申请号：US13194920

    申请日：2011-07-30

    申请人： Scott Smith ,  Leonard B. Richardson ,  Mark L. Jenson

    发明人： Scott Smith ,  Leonard B. Richardson ,  Mark L. Jenson

    IPC分类号： A61B18/14 ,  A61M25/01 ,  A61B18/18 ,  A61B18/20 ,  A61B19/00 ,  A61B18/00 ,  A61M25/00

    CPC分类号： A61B18/1492 ,  A61B18/1815 ,  A61B18/20 ,  A61B90/39 ,  A61B2018/00011 ,  A61B2018/00434 ,  A61B2018/00577 ,  A61B2018/00589 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61M25/0054 ,  A61M25/0113 ,  A61M25/0127 ,  A61M25/0138 ,  A61M25/0147

    摘要： A catheter is configured to access a renal artery. A lumen of the catheter's shaft is dimensioned to receive a flexible actuation member which extends between the shaft's proximal and distal ends. The actuation member is moveable within the lumen and subject to elastic deformation, friction, and/or whip along its length. A flexible support member is coupled to a distal end of the actuation member and extendible beyond a distal tip of the shaft. An RF ablation electrode at a distal end of the support member is configured to ablated perivascular renal nerve tissue. A position converter at the distal end of the shaft is configured to convert movement of the actuation member into one or both of controlled rotational and axial movement of the support member and electrode to one of a multiplicity of stable circumferential positions substantially free of elastic deformation, friction, and/or whip impacting actuation member movement.

    摘要翻译： 导管配置成进入肾动脉。 导管轴的内腔的尺寸被设计成容纳在轴的近端和远端之间延伸的柔性致动构件。 致动构件可在内腔内移动并且沿其长度受到弹性变形，摩擦和/或鞭状。 柔性支撑构件联接到致动构件的远端并且可延伸超过轴的远侧末端。 在支撑构件的远端处的RF消融电极被配置为消融血管周围肾神经组织。 在轴的远端处的位置转换器被配置为将致动构件的运动转换成支撑构件和电极的受控旋转和轴向运动到基本上没有弹性变形的多个稳定的圆周位置中的一个或两个， 摩擦和/或搅动撞击致动构件运动。

    RENAL ABLATION ELECTRODE WITH FORCE-ACTIVATABLE CONDUCTION APPARATUS
    9.
    发明申请
    RENAL ABLATION ELECTRODE WITH FORCE-ACTIVATABLE CONDUCTION APPARATUS 有权
    具有强力导联装置的RENAL ABLATION ELECTRODE

    公开(公告)号：US20120172870A1

    公开(公告)日：2012-07-05

    申请号：US13303130

    申请日：2011-11-22

    申请人： Mark L. Jenson ,  Scott Smith ,  David Sogard

    发明人： Mark L. Jenson ,  Scott Smith ,  David Sogard

    IPC分类号： A61B18/18

    CPC分类号： A61B18/1492 ,  A61B2018/00029 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61B2018/1465 ,  A61B2090/065

    摘要： An electrode is provided at a distal end of a catheter and dimensioned for deployment within a renal artery. A deformable cover of the electrode incorporates a force-activatable conduction apparatus. The cover is configured to conduct electrical energy only through a region or regions of the cover subject to deformation due to contact with a wall of the target vessel. The electrical energy is sufficient to ablate perivascular renal nerves proximate the deformed region or regions of the electrode cover. The cover is configured to prevent conduction of electrical energy through the cover in the absence of a deformation force applied to the cover.

    摘要翻译： 在导管的远端设置电极，其尺寸适于在肾动脉内展开。 电极的可变形的外壳包含一个力可激活的传导装置。 盖被配置成仅通过与目标容器的壁接触而受到变形的区域或区域传导电能。 电能足以消除靠近变形区域或电极盖的区域的血管周围肾神经。 盖被配置成在没有施加到盖的变形力的情况下防止电能通过盖的传导。

    Bipolar Off-Wall Electrode Device for Renal Nerve Ablation
    10.
    发明申请
    Bipolar Off-Wall Electrode Device for Renal Nerve Ablation 审中-公开
    用于肾神经消融的双极离壁电极装置

    公开(公告)号：US20120157993A1

    公开(公告)日：2012-06-21

    申请号：US13243736

    申请日：2011-09-23

    申请人： Mark L. Jenson ,  Scott Smith

    发明人： Mark L. Jenson ,  Scott Smith

    IPC分类号： A61B18/16

    CPC分类号： A61B18/1492 ,  A61B2018/00267 ,  A61B2018/00434 ,  A61B2018/00577 ,  A61B2018/00821 ,  A61B2018/00875

    摘要： A first spacing structure is provided at a distal end of a first catheter. The first spacing structure is configured to position at least one arterial electrode at a predefined distance away from a wall of the renal artery. A second spacing structure is provided at the distal end of the first catheter or at a distal end of a second catheter. The second spacing structure is configured to position at least one aortal electrode at a predefined distance away from a wall of the aorta. The arterial and aortal electrodes are operable as a bipolar electrode arrangement. The first and second spacing structures respectively maintain the arterial and aortal electrodes at a predefined distance away from the renal artery and aortal walls while electrical energy sufficient to ablate perivascular nerve tissue adjacent the renal artery and aortal walls is delivered by the bipolar electrode arrangement.

    摘要翻译： 第一间隔结构设置在第一导管的远端。 第一间隔结构构造成将远离肾动脉壁的预定距离定位至少一个动脉电极。 第二间隔结构设置在第一导管的远端处或在第二导管的远端处。 第二间隔结构被配置为将至少一个主动脉电极定位成远离主动脉壁的预定距离。 动脉和主动脉电极可操作为双极电极装置。 第一和第二间隔结构分别将动脉和主动脉电极保持在远离肾动脉和主动脉壁的预定距离处，同时通过双极电极装置输送足以消除邻近肾动脉和主动脉壁的血管周围神经组织的电能。