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1.Method of using 4-amino derivatives of 5-substituted mycophenolic acid 失效
标题翻译: 使用5-取代霉酚酸的4-氨基衍生物的方法公开(公告)号:US5512568A
公开(公告)日:1996-04-30
申请号:US198732
申请日:1994-02-18
申请人: David Morgans, Jr. , Eric B. Sjogren , David B. Smith , Francisco X. Talamas , Dean R. Artis , Alicia Cervantes , Todd R. Elworthy , Mario Fernandez , Fidencio Franco , Ronald C. Hawley , Teresa Lara , David G. Loughhead , Peter H. Nelson , John W. Patterson , Alejandra Trejo , Ann M. Waltos , Robert J. Weikert
发明人: David Morgans, Jr. , Eric B. Sjogren , David B. Smith , Francisco X. Talamas , Dean R. Artis , Alicia Cervantes , Todd R. Elworthy , Mario Fernandez , Fidencio Franco , Ronald C. Hawley , Teresa Lara , David G. Loughhead , Peter H. Nelson , John W. Patterson , Alejandra Trejo , Ann M. Waltos , Robert J. Weikert
IPC分类号: A61K31/34 , A61K31/365 , A61K31/38 , A61K31/40 , A61K31/4025 , A61P17/00 , A61P29/00 , A61P37/06 , C07D307/88 , C07D405/06 , C07D407/06 , C07D409/06 , A61K31/535
CPC分类号: C07D405/06 , C07D307/88 , C07D407/06 , C07D409/06
摘要: The disclosed derivatives of mycophenolic acid are therapeutic agents advantageous in the treatment of disease states indicated for mycophenolic acid and/or mycophenolate mofetil and other immunosuppressant agents.
摘要翻译: 公开的霉酚酸衍生物是治疗针对霉酚酸和/或霉酚酸酯和其它免疫抑制剂的疾病状态的治疗剂。
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公开(公告)号:US5493030A
公开(公告)日:1996-02-20
申请号:US198749
申请日:1994-02-18
申请人: David Morgans, Jr. , David B. Smith , Francisco X. Talamas , Dean R. Artis , Alicia Cervantes , Todd R. Elworthy , Mario Fernandez , Fidencio Franco , Ronald C. Hawley , Teresa Lara , David G. Loughhead , Peter H. Nelson , John W. Patterson , John C. Rohloff , Eric B. Sjogren , Alejandra Trejo , Ann M. Waltos , Robert J. Weikert
发明人: David Morgans, Jr. , David B. Smith , Francisco X. Talamas , Dean R. Artis , Alicia Cervantes , Todd R. Elworthy , Mario Fernandez , Fidencio Franco , Ronald C. Hawley , Teresa Lara , David G. Loughhead , Peter H. Nelson , John W. Patterson , John C. Rohloff , Eric B. Sjogren , Alejandra Trejo , Ann M. Waltos , Robert J. Weikert
IPC分类号: A61K31/34 , A61K31/365 , A61K31/38 , A61K31/40 , A61K31/4025 , A61K31/42 , A61P17/00 , A61P29/00 , A61P35/00 , A61P37/06 , C07D307/83 , C07D307/88 , C07D405/06 , C07D405/10 , C07D407/06 , C07D407/10 , C07D409/06 , C07D409/10 , C07D413/06 , C07D413/12 , C07F9/655 , C07D263/22
CPC分类号: C07D405/06 , C07D307/88 , C07D407/06 , C07D409/06 , C07D413/06 , C07F9/65517
摘要: The disclosed hexenoic acid side-chain derivatives of mycophenolic acid are therapeutic agents advantageous in the treatment of disease states indicated for mycophenolic acid and/or mycophenolate mofetil, including immune, inflammatory, tumor, proliferative, viral or psoriatic disorders.
摘要翻译: 公开的霉酚酸的己烯酸侧链衍生物是治疗剂,其用于治疗指示霉酚酸和/或霉酚酸酯的疾病状态,包括免疫,炎症,肿瘤,增殖性,病毒性或银屑病性疾病。
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公开(公告)号:US5444072A
公开(公告)日:1995-08-22
申请号:US198725
申请日:1994-02-18
申请人: John W. Patterson , David Morgans, Jr. , David B. Smith , Francisco X. Talamas , Dean R. Artis , Alicia Cervantes , Todd R. Elworthy , Mario Fernandez , Fidencio Franco , Ronald C. Hawley , Teresa Lara , David G. Loughhead , Peter H. Nelson , Eric B. Sjogren , Alejandra Trejo , Ann M. Waltos , Robert J. Weikert
发明人: John W. Patterson , David Morgans, Jr. , David B. Smith , Francisco X. Talamas , Dean R. Artis , Alicia Cervantes , Todd R. Elworthy , Mario Fernandez , Fidencio Franco , Ronald C. Hawley , Teresa Lara , David G. Loughhead , Peter H. Nelson , Eric B. Sjogren , Alejandra Trejo , Ann M. Waltos , Robert J. Weikert
IPC分类号: C07D307/88 , A61K20060101 , A61K31/34 , A61K31/341 , A61K31/365 , A61K31/38 , A61K31/395 , A61K31/40 , A61K31/4025 , A61K31/445 , A61K31/535 , A61K31/54 , A61P17/00 , A61P29/00 , A61P35/00 , A61P37/06 , C07D20060101 , C07D307/83 , C07D405/02 , C07D405/06 , C07D405/10 , C07D405/12 , C07D407/06 , C07D407/10 , C07D407/12 , C07D409/06 , C07D409/10 , C07D413/00 , C07D413/12 , C07D417/00 , C07D417/12
CPC分类号: C07D307/83
摘要: The disclosed 6-substituted derivatives of mycophenolic acid are therapeutic agents advantageous in the treatment of disease states indicated for mycophenolic acid and/or mycophenolate mofetil.
摘要翻译: 所公开的麦考酚酸的6-取代衍生物是治疗药物,其有利于治疗针对霉酚酸和/或霉酚酸酯的疾病状态。
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4.Method of using 4-amino 6-substituted mycophenolic acid and derivatives 失效
标题翻译: 使用4-氨基-6-取代霉酚酸及其衍生物的方法公开(公告)号:US5525602A
公开(公告)日:1996-06-11
申请号:US198741
申请日:1994-02-18
申请人: John W. Patterson , David Morgans, Jr. , Eric B. Sjogren , David B. Smith , Francisco X. Talamas , Dean R. Artis , Alicia Cervantes , Todd R. Elworthy , Mario Fernandez , Fidencio Franco , Ronald C. Hawley , Teresa Lara , David G. Loughhead , Peter H. Nelson , Alejandra Trejo , Ann M. Waltos , Robert J. Weikert
发明人: John W. Patterson , David Morgans, Jr. , Eric B. Sjogren , David B. Smith , Francisco X. Talamas , Dean R. Artis , Alicia Cervantes , Todd R. Elworthy , Mario Fernandez , Fidencio Franco , Ronald C. Hawley , Teresa Lara , David G. Loughhead , Peter H. Nelson , Alejandra Trejo , Ann M. Waltos , Robert J. Weikert
IPC分类号: A61K31/365 , A61K31/38 , A61K31/40 , A61K31/4025 , A61P17/00 , A61P29/00 , A61P35/00 , A61P37/06 , C07D307/88 , C07D405/06 , C07D407/06 , C07D409/06 , A61K31/535
CPC分类号: C07D307/88
摘要: The disclosed derivatives of mycophenolic acid are therapeutic agents advantageous in the treatment of disease states indicated for mycophenolic acid and/or mycophenolate mofetil and other immunosuppressant agents.
摘要翻译: 公开的霉酚酸衍生物是治疗针对霉酚酸和/或霉酚酸酯和其它免疫抑制剂的疾病状态的治疗剂。
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公开(公告)号:US5536747A
公开(公告)日:1996-07-16
申请号:US435255
申请日:1995-05-05
申请人: John W. Patterson , David Morgans, Jr. , David B. Smith , Fancisco X. Talamas , Dean R. Artis , Alicia Cervantes , Todd R. Elworthy , Mario Fernandez , Fidencio Franco , Ronald C. Hawley , Teresa Lara , David G. Loughhead , Peter H. Nelson , Eric B. Sjogren , Alejandra Trejo , Ann M. Waltos , Robert J. Weikert
发明人: John W. Patterson , David Morgans, Jr. , David B. Smith , Fancisco X. Talamas , Dean R. Artis , Alicia Cervantes , Todd R. Elworthy , Mario Fernandez , Fidencio Franco , Ronald C. Hawley , Teresa Lara , David G. Loughhead , Peter H. Nelson , Eric B. Sjogren , Alejandra Trejo , Ann M. Waltos , Robert J. Weikert
IPC分类号: C07D307/88 , A61K20060101 , A61K31/34 , A61K31/341 , A61K31/365 , A61K31/38 , A61K31/395 , A61K31/40 , A61K31/4025 , A61K31/445 , A61K31/535 , A61K31/54 , A61P17/00 , A61P29/00 , A61P35/00 , A61P37/06 , C07D20060101 , C07D307/83 , C07D405/02 , C07D405/06 , C07D405/10 , C07D405/12 , C07D407/06 , C07D407/10 , C07D407/12 , C07D409/06 , C07D409/10 , C07D413/00 , C07D413/12 , C07D417/00 , C07D417/12
CPC分类号: C07D307/83
摘要: The disclosed 6-substituted derivatives of mycophenolic acid are therapeutic agents advantageous in the treatment of disease states indicated for mycophenolic acid and/or mycophenolate mofetil.
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公开(公告)号:US5554612A
公开(公告)日:1996-09-10
申请号:US452243
申请日:1995-05-26
申请人: John W. Patterson , David Morgans, Jr. , Eric B. Sjogren , David B Smith , Francisco X. Talam as , Dean R. Artis , Alicia Cervantes , Todd R. Elworthy , Mario Fern andez , Fidencio Franco , Ronald C. Hawley , Teresa Lara , David G. Loughhead , Peter H. Nelson , Alejandra Trejo , Ann M. Waltos , Robert J. Weikert
发明人: John W. Patterson , David Morgans, Jr. , Eric B. Sjogren , David B Smith , Francisco X. Talam as , Dean R. Artis , Alicia Cervantes , Todd R. Elworthy , Mario Fern andez , Fidencio Franco , Ronald C. Hawley , Teresa Lara , David G. Loughhead , Peter H. Nelson , Alejandra Trejo , Ann M. Waltos , Robert J. Weikert
IPC分类号: A61K31/365 , A61K31/38 , A61K31/40 , A61K31/4025 , A61P17/00 , A61P29/00 , A61P35/00 , A61P37/06 , C07D307/88 , C07D405/06 , C07D407/06 , C07D409/06 , A61K31/535 , C07D413/12
CPC分类号: C07D307/88
摘要: The disclosed derivatives of mycophenolic acid are therapeutic agents advantageous in the treatment of disease states indicated for mycophenolic acid and/or mycophenolate mofetil and other immunosuppressant agents.
摘要翻译: 公开的霉酚酸衍生物是治疗针对霉酚酸和/或霉酚酸酯和其它免疫抑制剂的疾病状态的治疗剂。
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公开(公告)号:US5633279A
公开(公告)日:1997-05-27
申请号:US483042
申请日:1995-06-06
申请人: David Morgans, Jr. , David B. Smith , Francisco X. Talam as , Dean R. Artis , Alicia Cervantes , Todd R. Elworthy , Mario Fern andez , Fidencio Franco , Ronald C. Hawley , Teresa Lara , David G. Loughhead , Peter H. Nelson , John W. Patterson , John C. Rohloff , Eric B. Sjogren , Alejandra Trejo , Ann M. Waltos , Robert J. Weikert
发明人: David Morgans, Jr. , David B. Smith , Francisco X. Talam as , Dean R. Artis , Alicia Cervantes , Todd R. Elworthy , Mario Fern andez , Fidencio Franco , Ronald C. Hawley , Teresa Lara , David G. Loughhead , Peter H. Nelson , John W. Patterson , John C. Rohloff , Eric B. Sjogren , Alejandra Trejo , Ann M. Waltos , Robert J. Weikert
IPC分类号: A61K31/34 , A61K31/365 , A61K31/38 , A61K31/40 , A61K31/4025 , A61K31/42 , A61P17/00 , A61P29/00 , A61P35/00 , A61P37/06 , C07D307/83 , C07D307/88 , C07D405/06 , C07D405/10 , C07D407/06 , C07D407/10 , C07D409/06 , C07D409/10 , C07D413/06 , C07D413/12 , C07F9/655 , A61K31/445 , A61K31/535
CPC分类号: C07D405/06 , C07D307/88 , C07D407/06 , C07D409/06 , C07D413/06 , C07F9/65517
摘要: The disclosed hexenoic acid side-chain derivatives of mycophenolic acid are therapeutic agents advantageous in the treatment of disease states indicated for mycophenolic acid and/or mycophenolate mofetil, including immune, inflammatory, tumor, proliferative, viral or psoriatic disorders.
摘要翻译: 公开的霉酚酸的己烯酸侧链衍生物是治疗药物,其有利于治疗指示霉酚酸和/或霉酚酸酯的疾病状态,包括免疫,炎性,肿瘤,增殖性,病毒性或牛皮癣性疾病。
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公开(公告)号:US5538969A
公开(公告)日:1996-07-23
申请号:US452245
申请日:1995-05-26
申请人: David Morgans, Jr. , Eric B. Sjogren , David B. Smith , Francisco X. Talam as , Dean R. Artis , Alicia Cervantes , Todd R. Elworthy , Mario Fern andez , Fidencio Franco , Ronald C. Hawley , Teresa Lara , David G. Loughhead , Peter H. Nelson , John W. Patterson , Alejandra Trejo , Ann M. Waltos , Robert J. Weikert
发明人: David Morgans, Jr. , Eric B. Sjogren , David B. Smith , Francisco X. Talam as , Dean R. Artis , Alicia Cervantes , Todd R. Elworthy , Mario Fern andez , Fidencio Franco , Ronald C. Hawley , Teresa Lara , David G. Loughhead , Peter H. Nelson , John W. Patterson , Alejandra Trejo , Ann M. Waltos , Robert J. Weikert
IPC分类号: A61K31/34 , A61K31/365 , A61K31/38 , A61K31/40 , A61K31/4025 , A61P17/00 , A61P29/00 , A61P37/06 , C07D307/88 , C07D405/06 , C07D407/06 , C07D409/06 , A61K31/535 , C07D413/12
CPC分类号: C07D405/06 , C07D307/88 , C07D407/06 , C07D409/06
摘要: The disclosed derivatives of mycophenolic acid are therapeutic agents advantageous in the treatment of disease states indicated for mycophenolic acid and/or mycophenolate mofetil and other immunosuppressant agents.
摘要翻译: 公开的霉酚酸衍生物是治疗针对霉酚酸和/或霉酚酸酯和其它免疫抑制剂的疾病状态的治疗剂。
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