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公开(公告)号:US20090186347A1
公开(公告)日:2009-07-23
申请号:US12152141
申请日:2008-05-09
IPC分类号: C12Q1/68
CPC分类号: C12Q1/6883 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , C12Q2600/16 , C12Q2600/172
摘要: Correlations between polymorphisms and metabolic syndrome, insulin resistance, obesity, high blood pressure, dyslipidemia, diabetes and/or myocardial infarction are provided. Methods of diagnosing and treating metabolic syndrome, insulin resistance, obesity, high blood pressure, dyslipidemia, diabetes and/or myocardial infarction are provided. Systems and kits for diagnosis and treatment of metabolic syndrome, insulin resistance, obesity, high blood pressure, dyslipidemia, diabetes and/or myocardial infarction are provided.
摘要翻译: 提供多态性与代谢综合征之间的相关性,胰岛素抵抗,肥胖,高血压,血脂异常,糖尿病和/或心肌梗死。 提供诊断和治疗代谢综合征,胰岛素抵抗,肥胖,高血压,血脂异常,糖尿病和/或心肌梗死的方法。 提供了代谢综合征,胰岛素抵抗,肥胖,高血压,血脂异常,糖尿病和/或心肌梗塞的诊断和治疗的系统和试剂盒。
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公开(公告)号:US20080299125A1
公开(公告)日:2008-12-04
申请号:US11810694
申请日:2007-06-05
申请人: David A. Hinds , David R. Cox , Craig L. Hyde , Hakan Sakul
发明人: David A. Hinds , David R. Cox , Craig L. Hyde , Hakan Sakul
IPC分类号: C12Q1/68 , A61K39/395 , A61K38/16 , A01K67/027 , A61P25/24 , A61K31/7088 , G01N33/53
CPC分类号: C12Q1/6883 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158
摘要: The invention provides a collection of polymorphic sites associated with response to treatment by an SSRI or placebo in depression patients. The polymorphic sites and others in linkage disequilibrium with them are useful in determining whether to treat a patient with an SSRI or include a patient in a clinical trial to test an SSRI.
摘要翻译: 本发明提供了与抑郁症患者中SSRI或安慰剂治疗反应相关的多态性位点的集合。 与它们连锁不平衡的多态性位点和其他位点可用于确定是否用SSRI治疗患者或在临床试验中包括患者以测试SSRI。
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公开(公告)号:US07060444B1
公开(公告)日:2006-06-13
申请号:US10663418
申请日:2003-09-15
CPC分类号: G01N33/5091 , C12Q1/6876 , C12Q2600/142 , C12Q2600/158 , G01N2500/10
摘要: Disclosed are methods of identifying toxic agents, e.g., hepatotoxic agents, using differential gene expression.
摘要翻译: 公开了使用差异基因表达鉴定毒性试剂例如肝毒性试剂的方法。
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