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公开(公告)号:US09504457B2
公开(公告)日:2016-11-29
申请号:US13183603
申请日:2011-07-15
申请人: David Szabo , David Gale , Paul Johnson , Valerie Scott , Ben Morris , Greg Furnish , Trevor Beckett , Michael J. Trezza, II
发明人: David Szabo , David Gale , Paul Johnson , Valerie Scott , Ben Morris , Greg Furnish , Trevor Beckett , Michael J. Trezza, II
CPC分类号: A61B17/0057 , A61B17/0401 , A61B17/0467 , A61B17/0487 , A61B2017/00004 , A61B2017/00367 , A61B2017/00637 , A61B2017/00659 , A61B2017/0404 , A61B2017/0414 , A61B2017/0445 , A61B2017/0451 , A61B2017/0464 , A61B2017/06176
摘要: Vessel wound closure systems and method for sealing a puncture wound in a target vessel, such as those puncture wounds that occur from prior interventional procedures. A sealing member is deployed intravascularly into the target vessel, and an anchor member is deployed extravacularly of the target vessel. The sealing member and the anchor member are connected by a suture that may be drawn to tighten the sealing member and the anchor member relative to one another in order to effect the seal of the puncture wound. After tightening, the suture is secured to maintain the sealing member and the anchor member relative to one another in order to maintain the seal. Preferably, the anchor member, the suture and the sealing member are comprised of biocompatible, bioresorbable materials that are absorbed into the body after the sealing of the puncture wound has been achieved. The sealing member, suture and the anchor member are delivered by a delivery rod or other components over a guidewire or through an introducer already in place from the preceding interventional procedure.
摘要翻译: 血管伤口闭合系统和密封目标血管中穿刺伤口的方法,例如从先前介入手术发生的那些穿刺伤口。 密封构件在血管内部署到靶容器中,并且锚定构件被部署在目标血管的外侧。 密封构件和锚定构件通过缝合线连接,缝合线可以被拉伸以将密封构件和锚定构件相对于彼此紧固,以便实现穿刺伤口的密封。 紧固后,缝合线被固定以保持密封构件和锚固构件相对于彼此以便保持密封。 优选地,锚固构件,缝合线和密封构件由生物相容的生物可再吸收材料构成,其在已经实现了穿刺伤口的密封之后被吸收到身体中。 密封构件,缝合线和锚固构件通过导线或通过导引器的输送杆或其它部件从前述介入过程传送。
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公开(公告)号:US08267942B2
公开(公告)日:2012-09-18
申请号:US11317478
申请日:2005-12-23
申请人: David Szabo , David Gale , Paul Johnson , Valerie Scott , Ben Morris , Greg Furnish , Trevor Beckett , Michael J. Trezza, II
发明人: David Szabo , David Gale , Paul Johnson , Valerie Scott , Ben Morris , Greg Furnish , Trevor Beckett , Michael J. Trezza, II
IPC分类号: A61B17/04
CPC分类号: A61B17/0057 , A61B17/0401 , A61B17/0467 , A61B17/0487 , A61B2017/00004 , A61B2017/00367 , A61B2017/00637 , A61B2017/00659 , A61B2017/0404 , A61B2017/0414 , A61B2017/0445 , A61B2017/0451 , A61B2017/0464 , A61B2017/06176
摘要: Vessel wound closure systems and method for sealing a puncture wound in a target vessel, such as those puncture wounds that occur from prior interventional procedures. A sealing member is deployed intravascularly into the target vessel, and an anchor member is deployed extravascularly of the target vessel. The sealing member and the anchor member are connected by a suture that may be drawn to tighten the sealing member and the anchor member relative to one another in order to effect the seal of the puncture wound. After tightening, the suture is secured to maintain the sealing member and the anchor member relative to one another in order to maintain the seal. Preferably, the anchor member, the suture and the sealing member are comprised of biocompatible, bioresorbable materials that are absorbed into the body after the sealing of the puncture wound has been achieved. The sealing member, suture and the anchor member are delivered by a delivery rod or other components over a guidewire or through an introducer already in place from the preceding interventional procedure.
摘要翻译: 血管伤口闭合系统和密封目标血管中穿刺伤口的方法,例如从先前介入手术发生的那些穿刺伤口。 密封构件在血管内部署到靶容器中,并且锚定构件部署在靶血管的血管外。 密封构件和锚定构件通过缝合线连接,缝合线可以被拉伸以将密封构件和锚定构件相对于彼此紧固,以便实现穿刺伤口的密封。 紧固后,缝合线被固定以保持密封构件和锚固构件相对于彼此以便保持密封。 优选地,锚固构件,缝合线和密封构件由生物相容的生物可再吸收材料构成,其在已经实现了穿刺伤口的密封之后被吸收到身体中。 密封构件,缝合线和锚固构件通过导线或通过导引器的输送杆或其它部件从前述介入过程传送。
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公开(公告)号:US20110270307A1
公开(公告)日:2011-11-03
申请号:US13183603
申请日:2011-07-15
申请人: David Szabo , David Gale , Paul Johnson , Valerie Scott , Ben Morris , Greg Furnish , Trevor Beckett , Michael J. Trezza, II
发明人: David Szabo , David Gale , Paul Johnson , Valerie Scott , Ben Morris , Greg Furnish , Trevor Beckett , Michael J. Trezza, II
IPC分类号: A61B17/04
CPC分类号: A61B17/0057 , A61B17/0401 , A61B17/0467 , A61B17/0487 , A61B2017/00004 , A61B2017/00367 , A61B2017/00637 , A61B2017/00659 , A61B2017/0404 , A61B2017/0414 , A61B2017/0445 , A61B2017/0451 , A61B2017/0464 , A61B2017/06176
摘要: Vessel wound closure systems and method for sealing a puncture wound in a target vessel, such as those puncture wounds that occur from prior interventional procedures. A sealing member is deployed intravascularly into the target vessel, and an anchor member is deployed extravascularly of the target vessel. The sealing member and the anchor member are connected by a suture that may be drawn to tighten the sealing member and the anchor member relative to one another in order to effect the seal of the puncture wound. After tightening, the suture is secured to maintain the sealing member and the anchor member relative to one another in order to maintain the seal. Preferably, the anchor member, the suture and the sealing member are comprised of biocompatible, bioresorbable materials that are absorbed into the body after the sealing of the puncture wound has been achieved. The sealing member, suture and the anchor member are delivered by a delivery rod or other components over a guidewire or through an introducer already in place from the preceding interventional procedure.
摘要翻译: 血管伤口闭合系统和密封目标血管中穿刺伤口的方法,例如从先前介入手术发生的那些穿刺伤口。 密封构件在血管内部署到靶容器中,并且锚定构件部署在靶血管的血管外。 密封构件和锚定构件通过缝合线连接,缝合线可以被拉伸以将密封构件和锚定构件相对于彼此紧固,以便实现穿刺伤口的密封。 紧固后,缝合线被固定以保持密封构件和锚固构件相对于彼此以便保持密封。 优选地,锚固构件,缝合线和密封构件由生物相容的生物可再吸收材料构成,其在已经实现了穿刺伤口的密封之后被吸收到身体中。 密封构件,缝合线和锚固构件通过导线或通过导引器的输送杆或其它部件从前述介入过程传送。
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公开(公告)号:US20070150002A1
公开(公告)日:2007-06-28
申请号:US11317478
申请日:2005-12-23
申请人: David Szabo , David Gale , Paul Johnson , Valerie Scott , Ben Morris , Greg Furnish , Trevor Beckett , Michael Trezza
发明人: David Szabo , David Gale , Paul Johnson , Valerie Scott , Ben Morris , Greg Furnish , Trevor Beckett , Michael Trezza
IPC分类号: A61B17/04
CPC分类号: A61B17/0057 , A61B17/0401 , A61B17/0467 , A61B17/0487 , A61B2017/00004 , A61B2017/00367 , A61B2017/00637 , A61B2017/00659 , A61B2017/0404 , A61B2017/0414 , A61B2017/0445 , A61B2017/0451 , A61B2017/0464 , A61B2017/06176
摘要: Vessel wound closure systems and method for sealing a puncture wound in a target vessel, such as those puncture wounds that occur from prior interventional procedures. A sealing member is deployed intravascularly into the target vessel, and an anchor member is deployed extravascularly of the target vessel. The sealing member and the anchor member are connected by a suture that may be drawn to tighten the sealing member and the anchor member relative to one another in order to effect the seal of the puncture wound. After tightening, the suture is secured to maintain the sealing member and the anchor member relative to one another in order to maintain the seal. Preferably, the anchor member, the suture and the sealing member are comprised of biocompatible, bioresorbable materials that are absorbed into the body after the sealing of the puncture wound has been achieved. The sealing member, suture and the anchor member are delivered by a delivery rod or other components over a guidewire or through an introducer already in place from the preceding interventional procedure.
摘要翻译: 血管伤口闭合系统和密封目标血管中穿刺伤口的方法,例如从先前介入手术发生的那些穿刺伤口。 密封构件在血管内部署到靶容器中,并且锚定构件部署在靶血管的血管外。 密封构件和锚定构件通过缝合线连接,缝合线可以被拉伸以将密封构件和锚定构件相对于彼此紧固,以便实现穿刺伤口的密封。 紧固后,缝合线被固定以保持密封构件和锚固构件相对于彼此以便保持密封。 优选地,锚固构件,缝合线和密封构件由生物相容的生物可再吸收材料构成,其在已经实现了穿刺伤口的密封之后被吸收到身体中。 密封构件,缝合线和锚固构件通过导线或通过导引器的输送杆或其它部件从前述介入过程传送。
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公开(公告)号:US20070149987A1
公开(公告)日:2007-06-28
申请号:US11317039
申请日:2005-12-22
申请人: Parris Wellman , Bryan Ogle , Paul Johnson , David Szabo , Benjamin Wicks , Trevor Beckett
发明人: Parris Wellman , Bryan Ogle , Paul Johnson , David Szabo , Benjamin Wicks , Trevor Beckett
IPC分类号: A61B17/04
CPC分类号: A61B17/0057 , A61B17/0469 , A61B17/0485 , A61B17/0487 , A61B2017/00637 , A61B2017/00663 , A61B2017/00672 , A61B2017/0458 , A61B2017/0461 , A61B2017/0462 , A61B2017/06176
摘要: A vessel wound closure device that separately deploys a suture and a snare within a vessel to produce a stitch across a puncture site of a vessel. Once deployed within the vessel, the suture is captured within the snare, withdrawn, and then secured to provide a stitch across the puncture site of the vessel. The vessel wound closure device minimizes the amount of material introduced or left within the vessel or between edges of the puncture site, maximizes healing of the puncture site, and renders the vessel amenable to subsequent interventional or therapeutic procedures at or near the same site.
摘要翻译: 一种容器伤口闭合装置,其在容器内单独铺设缝线和圈套,以在血管穿刺部位产生缝合。 一旦部署在血管内,将缝合线捕获在圈套内,取出,然后固定,以在血管穿刺部位提供缝合线。 容器伤口闭合装置使引入或留在容器内或留在穿刺部位的边缘之间的材料的量最小化,使穿刺部位的愈合最大化,并且使得容器适于在同一部位处或附近的随后介入或治疗程序。
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公开(公告)号:US10301167B2
公开(公告)日:2019-05-28
申请号:US15226968
申请日:2016-08-03
申请人: Paul Johnson , Thomas D'Alesandro , Mark Butsch
发明人: Paul Johnson , Thomas D'Alesandro , Mark Butsch
摘要: An automated liquid inventory monitoring and inventory reconciliation system. The system uses a liquid densitometer to precisely measure the density of liquid being dispensed. This allows the system to account for the significant temperature-induced volume variations existing in common liquids such as gasoline. In the preferred embodiments, a fuel inventory processor tracks the quantity of fuel loaded into the tank and the quantity of fuel dispensed to maintain an ongoing computation of the quantity of fuel that should be present in the tank. An accurate tank depth measurement device is also employed. The processor compares the tank depth measurement to the computed quantity of fuel in the tank and uses the values to create an updated tank strapping chart.
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公开(公告)号:US20160228107A1
公开(公告)日:2016-08-11
申请号:US14878777
申请日:2015-10-08
申请人: Spencer Madsen , Mike Fogarty , Paul Johnson , John Langell
发明人: Spencer Madsen , Mike Fogarty , Paul Johnson , John Langell
CPC分类号: A61B17/0057 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/3417 , A61B2017/0046 , A61B2017/00637 , A61B2017/00663 , A61B2017/0409 , A61B2017/0414 , A61B2017/0472 , A61B2017/346
摘要: A self-contained, port-closing trocar and method of use which may include an elongated body having a first end, a second end opposite the first end, and a side wall between the first end and the second end, the body further including at least two channels therein, each of the channels originating near the second end, running parallel to the elongated body, and curving towards and forming an opening in the side wall near the first end. The self-closing trocar may also include at least two needles, each disposed within one of the at least two channels, and a handle insertable into the second end of the elongated body, the handle having at least two needle drivers coupled thereto, each needle driver being insertable into one of the at least two channels and engagable with an end of a needle.
摘要翻译: 一种独立的封口套管针和使用方法,其可以包括具有第一端,与第一端相对的第二端和在第一端和第二端之间的侧壁的细长主体,所述主体还包括在 在其中的至少两个通道中,每个通道始终靠近第二端,平行于细长主体延伸,并且朝向并在第一端附近的侧壁中形成开口弯曲。 自封闭套管针还可以包括至少两个针,每个针布置在至少两个通道中的一个中,并且可插入到细长主体的第二端的手柄,手柄具有与之相连的至少两个针驱动器,每个针 驾驶员可以插入到所述至少两个通道中的一个中并且可与针的一端接合。
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公开(公告)号:US08470577B2
公开(公告)日:2013-06-25
申请号:US12721599
申请日:2010-03-11
申请人: Paul Johnson , Robert L. Martuza , Samuel D. Rabkin , Tomoki Todo
发明人: Paul Johnson , Robert L. Martuza , Samuel D. Rabkin , Tomoki Todo
IPC分类号: C12N7/00 , C12N7/01 , A61K39/245
CPC分类号: A61K39/245 , A61K35/763 , A61K35/768 , A61K38/162 , A61K48/00 , A61K2039/5254 , A61K2039/5256 , A61K2039/53 , A61K2039/585 , C12N7/00 , C12N15/86 , C12N2710/16632 , C12N2710/16634 , C12N2710/16643 , C12N2710/16662 , C12N2710/16671
摘要: The invention provides viral vectors (e.g., herpes viral vectors) and methods of using these vectors to treat disease.
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公开(公告)号:US20120226945A1
公开(公告)日:2012-09-06
申请号:US13470856
申请日:2012-05-14
申请人: Paul Johnson , Colin R. Penfold
发明人: Paul Johnson , Colin R. Penfold
IPC分类号: G06F11/07
CPC分类号: G06F9/466 , G06F11/0778 , G06F11/0793 , G06F11/1474
摘要: A method, system and computer program product for handling a unit of work in a transaction processing system, in which the system comprises one or more production regions operating minimal or no diagnostic functions and one or more diagnostic regions operating maximal or full diagnostic functions. A unit of work is received, which is routed to a production region. After receiving a notification that the work has failed, the work is routed to a diagnostic region.
摘要翻译: 一种用于处理事务处理系统中的工作单元的方法,系统和计算机程序产品,其中所述系统包括操作最小或不具有诊断功能的一个或多个生产区域以及操作最大或全部诊断功能的一个或多个诊断区域。 接收到一个工作单元,该单元被转送到生产区域。 在收到工作失败的通知后,工作将路由到诊断区域。
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公开(公告)号:US08186506B2
公开(公告)日:2012-05-29
申请号:US11130325
申请日:2005-05-16
申请人: David P. Kanios , Juan A. Mantelle , Paul Johnson , Chensheng Li
发明人: David P. Kanios , Juan A. Mantelle , Paul Johnson , Chensheng Li
IPC分类号: B65D81/26
CPC分类号: A61K9/7061 , A61F15/001 , A61J1/00 , A61K9/7069 , B65D81/268
摘要: A device and method for stabilizing a drug, particularly a chiral drug or the active enantiomer(s) thereof, in a carrier composition of a transdermal delivery system prior to the systems use by providing a product packaging system to prevent or control degradation reactions that can result from certain packaging materials and moisture contamination, while at the same time providing a child-resistant wrapping for the transdermal system.
摘要翻译: 一种用于在系统使用之前将药物,特别是手性药物或其活性对映异构体稳定在透皮递送系统的载体组合物中的装置和方法,其通过提供产品包装系统来预防或控制降解反应 来自某些包装材料和水分污染,同时为透皮系统提供抗儿童包装。
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