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28 条记录 (耗时 0.039 秒)

    Antidepressant arylpiperazine derivatives of heterocycle-fused benzodioxans
    1.
    发明申请
    Antidepressant arylpiperazine derivatives of heterocycle-fused benzodioxans 审中-公开
    杂环稠合苯并二恶烷的抗抑郁芳基哌嗪衍生物

    公开(公告)号：US20060276481A1

    公开(公告)日：2006-12-07

    申请号：US11505663

    申请日：2006-08-16

    申请人： Deborah Evrard ,  Dahui Zhou ,  Gary Stack ,  Aranapakam Venkatesan ,  Amedeo Failli ,  Susan Croce

    发明人： Deborah Evrard ,  Dahui Zhou ,  Gary Stack ,  Aranapakam Venkatesan ,  Amedeo Failli ,  Susan Croce

    IPC分类号： A61K31/496 ,  C07D491/02

    CPC分类号： C07D491/04 ,  Y02P20/582

    摘要： Compounds of the formula I: are useful for the treatment of depression (including but not limited to major depressive disorder, childhood depression and dysthymia), anxiety, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder (also known as pre-menstrual syndrome), attention deficit disorder (with and without hyperactivity), obsessive-compulsive disorder, social anxiety disorder, generalized anxiety disorder, obesity, eating disorders such as anorexia nervosa and bulimia nervosa, vasomotor flushing, cocaine and alcohol addiction, sexual dysfunction and related illnesses.

    摘要翻译： 式I化合物可用于治疗抑郁症（包括但不限于重度抑郁症，儿童抑郁症和抑郁症），焦虑症，恐慌症，创伤后应激障碍，经前期焦虑症（也称为月经前） 综合征），注意缺陷障碍（伴有和不伴有多动症），强迫症，社会焦虑症，广泛性焦虑症，肥胖症，进食障碍如神经性厌食症和神经性贪食症，血管舒缩性潮红，可卡因和酒精成瘾，性功能障碍及相关 疾病

    Benzodioxane and benzodioxolane derivatives and uses thereof
    4.
    发明申请
    Benzodioxane and benzodioxolane derivatives and uses thereof 审中-公开
    苯并二恶烷和苯并二氧杂环戊烷衍生物及其用途

    公开(公告)号：US20060241172A1

    公开(公告)日：2006-10-26

    申请号：US11409466

    申请日：2006-04-21

    申请人： Dahui Zhou ,  Gary Stack ,  Jonathan Gross ,  Hong Gao

    发明人： Dahui Zhou ,  Gary Stack ,  Jonathan Gross ,  Hong Gao

    IPC分类号： A61K31/36 ,  C07D319/14

    CPC分类号： C07D319/20 ,  C07D317/46 ,  C07D409/04

    摘要： Compounds of formula I or pharmaceutically acceptable salts thereof are provided: wherein each of R1, R2, R3, R4, y, n, m, and Ar are as defined, and described in classes and subclasses herein, which are agonists or partial agonists of the 2C subtype of brain serotonin receptors. The compounds, and compositions containing the compounds, can be used to treat a variety of central nervous system disorders such as schizophrenia.

    摘要翻译： 提供式I化合物或其药学上可接受的盐：其中R 1，R 2，R 3，R 4， y，n，m和Ar定义如下，并且在本文的类别和亚类中描述，其是脑5-羟色胺受体的2C亚型的激动剂或部分激动剂。 化合物和含有这些化合物的组合物可用于治疗各种中枢神经系统疾病如精神分裂症。

    Antidepressant azaheterocyclylmethyl derivatives of heterocycle-fused benzodioxans
    6.
    发明申请
    Antidepressant azaheterocyclylmethyl derivatives of heterocycle-fused benzodioxans 失效
    杂环稠合苯并二恶烷的抗抑郁药氮杂环甲基衍生物

    公开(公告)号：US20070004702A1

    公开(公告)日：2007-01-04

    申请号：US11513705

    申请日：2006-08-31

    申请人： Dahui Zhou ,  Gary Stack

    发明人： Dahui Zhou ,  Gary Stack

    IPC分类号： A61K31/4741 ,  C07D491/02

    CPC分类号： C07D491/04

    摘要： Compounds of the Formula: are useful for the treatment of depression (including but not limited to major depressive disorder, childhood depression and dysthymia), anxiety, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder (also known as pre-menstrual syndrome), attention deficit disorder (with and without hyperactivity), obsessive compulsive disorder, social anxiety disorder, generalized anxiety disorder, obesity, eating disorders such as anorexia nervosa and bulimia nervosa, vasomotor flushing, cocaine and alcohol addiction, sexual dysfunction and related illnesses.

    摘要翻译： 式的化合物可用于治疗抑郁症（包括但不限于严重抑郁症，儿童抑郁症和抑郁症），焦虑症，惊恐障碍，创伤后应激障碍，经前期焦虑障碍（也称为月经前综合征 ），注意力缺陷障碍（伴有和不伴有多动症），强迫症，社会焦虑症，广泛性焦虑症，肥胖症，进食障碍如神经性厌食症和神经性贪食症，血管舒缩性潮红，可卡因和酒精成瘾，性功能障碍及相关疾病。

    Antidepressant cycloalkylamine derivatives of 2,3-dihydro-1,4-benzodioxan
    8.
    发明申请
    Antidepressant cycloalkylamine derivatives of 2,3-dihydro-1,4-benzodioxan 审中-公开

    公开(公告)号：US20060160881A1

    公开(公告)日：2006-07-20

    申请号：US11372716

    申请日：2006-03-10

    申请人： Deborah Evrard ,  Uresh Shah ,  Gary Stack

    发明人： Deborah Evrard ,  Uresh Shah ,  Gary Stack

    IPC分类号： A61K31/405 ,  A61K31/381 ,  A61K31/335

    CPC分类号： C07D405/12

    摘要： Compounds of the Formula I: are useful for the treatment of depression (including but not limited to major depressive disorder, childhood depression and dysthymia), anxiety, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder (also known as pre-menstrual syndrome), attention deficit disorder (with and without hyperactivity), obsessive compulsive disorder, social anxiety disorder, generalized anxiety disorder, obesity, eating disorders such as anorexia nervosa and bulimia nervosa, vasomotor flushing, cocaine and alcohol addiction, sexual dysfunction and related illnesses.

    Antidepressant cycloalkylamine derivatives of 2,3-dihydro-1,4-Benzodioxan
    9.
    发明申请
    Antidepressant cycloalkylamine derivatives of 2,3-dihydro-1,4-Benzodioxan 失效
    2,3-二氢-1,4-苯并二恶烷的抗抑郁环烷基胺衍生物

    公开(公告)号：US20060148881A1

    公开(公告)日：2006-07-06

    申请号：US11373666

    申请日：2006-03-10

    申请人： Deborah Evrard ,  Uresh Shah ,  Gary Stack

    发明人： Deborah Evrard ,  Uresh Shah ,  Gary Stack

    IPC分类号： A61K31/404 ,  A61K31/381 ,  C07D409/02 ,  C07D405/02

    CPC分类号： C07D405/12

    摘要： Compounds of the Formula I: are useful for the treatment of depression (including but not limited to major depressive disorder, childhood depression and dysthymia), anxiety, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder (also known as pre-menstrual syndrome), attention deficit disorder (with and without hyperactivity), obsessive compulsive disorder, social anxiety disorder, generalized anxiety disorder, obesity, eating disorders such as anorexia nervosa and bulimia nervosa, vasomotor flushing, cocaine and alcohol addiction, sexual dysfunction and related illnesses.

    摘要翻译： 式I化合物可用于治疗抑郁症（包括但不限于重度抑郁障碍，儿童抑郁症和心境恶化），焦虑症，惊恐障碍，创伤后应激障碍，经前期焦虑障碍（也称月经前） 综合征），注意缺陷障碍（伴有和不伴有多动症），强迫症，社会焦虑症，广泛性焦虑症，肥胖症，进食障碍如神经性厌食症和神经性贪食症，血管舒缩性潮红，可卡因和酒精成瘾，性功能障碍及相关疾病 。

    Antidepressant piperidine derivatives of heterocyclefused benzodioxans
    10.
    发明申请
    Antidepressant piperidine derivatives of heterocyclefused benzodioxans 失效
    杂环烯基苯并二恶烷的抗抑郁药哌啶衍生物

    公开(公告)号：US20050228009A1

    公开(公告)日：2005-10-13

    申请号：US11142787

    申请日：2005-06-01

    申请人： Michael Webb ,  Gary Stack ,  Magda Asselin ,  Deborah Evrard

    发明人： Michael Webb ,  Gary Stack ,  Magda Asselin ,  Deborah Evrard

    IPC分类号： C07D491/04 ,  C07D498/04 ,  A61K31/4741 ,  A61K31/4439 ,  C07D491/02

    CPC分类号： C07D491/04

    摘要： Compounds of the Formula: are useful for the treatment of depression (including but not limited to major depressive disorder, childhood depression and dysthymia), anxiety, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder (also known as pre-menstrual syndrome), attention deficit disorder (with and without hyperactivity), obsessive compulsive disorder, social anxiety disorder, generalized anxiety disorder, obesity, eating disorders such as anorexia nervosa and bulimia nervosa, vasomotor flushing, cocaine and alcohol addiction, sexual dysfunction and related illnesses.

    摘要翻译： 式的化合物可用于治疗抑郁症（包括但不限于严重抑郁症，儿童抑郁症和抑郁症），焦虑症，惊恐障碍，创伤后应激障碍，经前期焦虑障碍（也称为月经前综合征 ），注意力缺陷障碍（伴有和不伴有多动症），强迫症，社会焦虑症，广泛性焦虑症，肥胖症，进食障碍如神经性厌食症和神经性贪食症，血管舒缩性潮红，可卡因和酒精成瘾，性功能障碍及相关疾病。