公开(公告)号：US20080116490A1

公开(公告)日：2008-05-22

申请号：US11583262

申请日：2006-10-19

申请人： Duncan R. Stewart ,  William M. Tong ,  R. Stanley Williams ,  Philip J. Kuekes ,  Sean Xiao-an Zhang ,  Kevin F. Peters ,  Kenneth J. Ward

发明人： Duncan R. Stewart ,  William M. Tong ,  R. Stanley Williams ,  Philip J. Kuekes ,  Sean Xiao-an Zhang ,  Kevin F. Peters ,  Kenneth J. Ward

IPC分类号： H01L27/10 ,  H01L29/73

CPC分类号： G01N27/128 ,  Y10S977/762 ,  Y10S977/957

摘要： A sensing method includes exposing a nano-transducer having a controlled surface to a sample including at least one species. Adsorption of the species on the nano-transducer is transduced to a measurable signal as a function of time. Desorption of the species from the nano-transducer is also transduced to a measurable signal as a function of time. A residence time of the at least one species adsorbed on the nano-transducer is extracted from the measurable signals. The adsorption and desorption each define an individual measurable event.

摘要翻译： 感测方法包括将具有受控表面的纳米换能器暴露于包括至少一种的样品。 物种在纳米转换器上的吸附作为时间的函数被转导到可测量的信号。 物种从纳米转换器的解吸也被转换为可测量的信号作为时间的函数。 从可测量信号中提取吸附在纳米换能器上的至少一种物质的停留时间。 吸附和解吸各自定义一个单独的可测量事件。

公开(公告)号：US07388200B2

公开(公告)日：2008-06-17

申请号：US11583262

申请日：2006-10-19

申请人： Duncan R. Stewart ,  William M. Tong ,  R. Stanley Williams ,  Philip J. Kuekes ,  Sean Xiao-an Zhang ,  Kevin F. Peters ,  Kenneth J. Ward

发明人： Duncan R. Stewart ,  William M. Tong ,  R. Stanley Williams ,  Philip J. Kuekes ,  Sean Xiao-an Zhang ,  Kevin F. Peters ,  Kenneth J. Ward

IPC分类号： G01N27/26 ,  G01N33/00

CPC分类号： G01N27/128 ,  Y10S977/762 ,  Y10S977/957

摘要： A sensing method includes exposing a nano-transducer having a controlled surface to a sample including at least one species. Adsorption of the species on the nano-transducer is transduced to a measurable signal as a function of time. Desorption of the species from the nano-transducer is also transduced to a measurable signal as a function of time. A residence time of the at least one species adsorbed on the nano-transducer is extracted from the measurable signals. The adsorption and desorption each define an individual measurable event.

摘要翻译： 感测方法包括将具有受控表面的纳米换能器暴露于包括至少一种的样品。 物种在纳米转换器上的吸附作为时间的函数被转导到可测量的信号。 物种从纳米转换器的解吸也被转换为可测量的信号作为时间的函数。 从可测量信号中提取吸附在纳米换能器上的至少一种物质的停留时间。 吸附和解吸各自定义一个单独的可测量事件。

公开(公告)号：US06255267B1

公开(公告)日：2001-07-03

申请号：US08610454

申请日：1996-03-04

申请人： Bala C. Nayar ,  Ronnie A. Carroll ,  Kenneth J. Ward

发明人： Bala C. Nayar ,  Ronnie A. Carroll ,  Kenneth J. Ward

IPC分类号： C11D3395

CPC分类号： C11D3/225 ,  C11D1/004 ,  C11D1/006 ,  C11D1/22 ,  C11D1/28 ,  C11D1/523 ,  C11D1/83 ,  C11D1/835 ,  C11D3/222

摘要： The present invention is an improved liquid toilet bowl cleanser comprising a fluorosurfactant coating agent, an anionic or non-ionic cleaner and a rheology control agent together with other minor excipients. The flurosurfactant continually adheres to and coats the porcelain surface of the toilet bowl during the active life of the cleanser composition preventing the formation of toilet bowl stains and mineral deposits for a substantial period of time after manual cleaning.

摘要翻译： 本发明是一种改进的液体马桶清洁剂，其包含含氟表面活性剂包衣剂，阴离子或非离子清洁剂和流变控制剂以及其它次要赋形剂。 在清洁剂组合物的活性寿命期间，氟代表面活性剂不断地粘附并涂覆马桶的瓷表面，防止在手动清洁之后大量时间形成马桶碗污渍和矿物沉积物。

公开(公告)号：US08058079B2

公开(公告)日：2011-11-15

申请号：US12135582

申请日：2008-06-09

申请人： Philip H. Harding ,  Christopher C. Beatty ,  Kenneth J. Ward

发明人： Philip H. Harding ,  Christopher C. Beatty ,  Kenneth J. Ward

IPC分类号： G01N33/553

CPC分类号： G01N33/54313 ,  B01F13/0059 ,  B01F15/0201 ,  B01F15/0233 ,  B01L3/502761 ,  B01L2200/0668 ,  B01L2300/0803 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2400/0409 ,  B01L2400/043 ,  B03C1/01 ,  G01N33/5432

摘要： An automated assay system includes a platform and a rotatable coupon removably positioned within or on the platform. The rotatable coupon includes a plurality of discrete tracks, each of the plurality of discrete tracks configured to contain microfluidic volumes. At least one magnet is operatively disposed on the platform, the rotatable coupon, or combinations thereof, and the at least one magnet is configured to generate a magnetic field at a predetermined area of the rotatable coupon. A motor is operatively connected to the rotatable coupon.

摘要翻译： 自动化测定系统包括可移除地定位在平台内或平台上的平台和可旋转的优惠券。 可旋转券包括多个离散轨道，多个离散轨道中的每一个配置成容纳微流体积。 至少一个磁体可操作地设置在平台上，可旋转的优惠券或其组合上，并且至少一个磁体被配置为在可旋转优惠券的预定区域处产生磁场。 马达可操作地连接到可旋转的优惠券。

公开(公告)号：US07648220B2

公开(公告)日：2010-01-19

申请号：US11739057

申请日：2007-04-23

申请人： Isaac V. Farr ,  David R. Otis, Jr. ,  Casey T. Miller ,  Christie Dudenhoefer ,  Kenneth J. Ward

发明人： Isaac V. Farr ,  David R. Otis, Jr. ,  Casey T. Miller ,  Christie Dudenhoefer ,  Kenneth J. Ward

IPC分类号： B41J29/393

CPC分类号： B41J29/393 ,  B41J2/17566 ,  B41J2/2139

摘要： Various apparatus and methods relating to determining a quantity measurement of fluid ejected by drop-on-demand nozzles and modifying the ejection parameters based upon the quantity measurement.

摘要翻译： 关于确定由按需喷嘴喷射的流体的量测量的各种装置和方法，以及基于量测量修改喷射参数。

公开(公告)号：US20080259107A1

公开(公告)日：2008-10-23

申请号：US11739057

申请日：2007-04-23

申请人： Isaac V. Farr ,  David R. Otis ,  Casey T. Miller ,  Christie Dudenhoefer ,  Kenneth J. Ward

发明人： Isaac V. Farr ,  David R. Otis ,  Casey T. Miller ,  Christie Dudenhoefer ,  Kenneth J. Ward

IPC分类号： B41J29/38

CPC分类号： B41J29/393 ,  B41J2/17566 ,  B41J2/2139

摘要： Various apparatus and methods relating to determining a quantity measurement of fluid ejected by drop-on-demand nozzles and modifying the ejection parameters based upon the quantity measurement.

摘要翻译： 关于确定由按需喷嘴喷射的流体的量测量的各种装置和方法，以及基于量测量修改喷射参数。

公开(公告)号：US20080102537A1

公开(公告)日：2008-05-01

申请号：US11590263

申请日：2006-10-31

申请人： Philip H. Harding ,  Christopher C. Beatty ,  Kenneth J. Ward

发明人： Philip H. Harding ,  Christopher C. Beatty ,  Kenneth J. Ward

IPC分类号： C12M1/34 ,  G01N33/558 ,  G01N33/546

CPC分类号： G01N33/54313 ,  B01F13/0059 ,  B01F15/0201 ,  B01F15/0233 ,  B01L3/502761 ,  B01L2200/0668 ,  B01L2300/0803 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2400/0409 ,  B01L2400/043 ,  B03C1/01 ,  G01N33/5432

摘要： A method of detecting analytes in a microfluidic sample includes introducing at least one type of analyte, at least one type of carrier particle, and a fluid into a mixing chamber of a system. The at least one type of analyte binds to a site on the at least one type of carrier particle to form a microfluidic suspension including at least one analyte-bound particle suspended in the fluid. The at least one analyte-bound particle is separated from the fluid by exposing the suspension to physical forces, magnetic forces, or combinations thereof. A spectrophotometric property of a solution is altered using the at least one analyte-bound particle. The altered spectrophotometric property is measured with an optical detection system.

摘要翻译： 检测微流体样品中的分析物的方法包括将至少一种类型的分析物，至少一种类型的载体颗粒和流体引入系统的混合室中。 所述至少一种类型的分析物结合至少一种类型的载体颗粒上的位点以形成包含悬浮在流体中的至少一种分析物结合颗粒的微流体悬浮液。 通过将悬浮液暴露于物理力，磁力或其组合，使至少一种分析物结合的颗粒与流体分离。 使用至少一种分析物结合的颗粒来改变溶液的分光光度特性。 用光学检测系统测量改变的分光光度特性。

公开(公告)号：US20080240996A1

公开(公告)日：2008-10-02

申请号：US12135582

申请日：2008-06-09

申请人： Philip H. Harding ,  Christopher C. Beatty ,  Kenneth J. Ward

发明人： Philip H. Harding ,  Christopher C. Beatty ,  Kenneth J. Ward

IPC分类号： G01N21/01 ,  B01J19/00

CPC分类号： G01N33/54313 ,  B01F13/0059 ,  B01F15/0201 ,  B01F15/0233 ,  B01L3/502761 ,  B01L2200/0668 ,  B01L2300/0803 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2400/0409 ,  B01L2400/043 ,  B03C1/01 ,  G01N33/5432

摘要： An automated assay system includes a platform and a rotatable coupon removably positioned within or on the platform. The rotatable coupon includes a plurality of discrete tracks, each of the plurality of discrete tracks configured to contain microfluidic volumes. At least one magnet is operatively disposed on the platform, the rotatable coupon, or combinations thereof, and the at least one magnet is configured to generate a magnetic field at a predetermined area of the rotatable coupon. A motor is operatively connected to the rotatable coupon.

摘要翻译： 自动化测定系统包括可移除地定位在平台内或平台上的平台和可旋转的优惠券。 可旋转券包括多个离散轨道，多个离散轨道中的每一个配置成容纳微流体体积。 至少一个磁体可操作地设置在平台上，可旋转的优惠券或其组合上，并且至少一个磁体被配置为在可旋转优惠券的预定区域产生磁场。 马达可操作地连接到可旋转的优惠券。

公开(公告)号：US4975581A

公开(公告)日：1990-12-04

申请号：US369217

申请日：1989-06-21

申请人： Mark R. Robinson ,  Kenneth J. Ward ,  Robert P. Eaton ,  David M. Haaland

发明人： Mark R. Robinson ,  Kenneth J. Ward ,  Robert P. Eaton ,  David M. Haaland

IPC分类号： G01N33/49 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1455 ,  A61B5/1459 ,  G01N21/35 ,  G01N21/55 ,  G01N33/487

CPC分类号： G01N21/552 ,  A61B5/14532 ,  A61B5/1455 ,  A61B5/1459 ,  A61B5/6876 ,  A61B5/6884 ,  G01N21/359 ,  G01N2201/129

摘要： The characteristics of a biological fluid sample having an analyte are determined from a model constructed from plural known biological fluid samples. The model is a function of the concentration of materials in the known fluid samples as a function of absorption of wideband infrared energy. The wideband infrared energy is coupled to the analyte containing sample so there is differential absorption of the infrared energy as a function of the wavelength of the wideband infrared energy incident on the analyte containing sample. The differential absorption causes intensity variations of the infrared energy incident on the analyte containing sample as a function of sample wavelength of the energy, and concentration of the unknown analyte is determined from the thus-derived intensity variations of the infrared energy as a function of wavelength from the model absorption versus wavelength function.

公开(公告)号：US07384798B2

公开(公告)日：2008-06-10

申请号：US11590263

申请日：2006-10-31

申请人： Philip H. Harding ,  Christopher C. Beatty ,  Kenneth J. Ward

发明人： Philip H. Harding ,  Christopher C. Beatty ,  Kenneth J. Ward

IPC分类号： G01N33/553

CPC分类号： G01N33/54313 ,  B01F13/0059 ,  B01F15/0201 ,  B01F15/0233 ,  B01L3/502761 ,  B01L2200/0668 ,  B01L2300/0803 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2400/0409 ,  B01L2400/043 ,  B03C1/01 ,  G01N33/5432

摘要： A method of detecting analytes in a microfluidic sample includes introducing at least one type of analyte, at least one type of carrier particle, and a fluid into a mixing chamber of a system. The at least one type of analyte binds to a site on the at least one type of carrier particle to form a microfluidic suspension including at least one analyte-bound particle suspended in the fluid. The at least one analyte-bound particle is separated from the fluid by exposing the suspension to physical forces, magnetic forces, or combinations thereof. A spectrophotometric property of a solution is altered using the at least one analyte-bound particle. The altered spectrophotometric property is measured with an optical detection system.

摘要翻译： 检测微流体样品中的分析物的方法包括将至少一种类型的分析物，至少一种类型的载体颗粒和流体引入系统的混合室中。 所述至少一种类型的分析物结合至少一种类型的载体颗粒上的位点以形成包含悬浮在流体中的至少一种分析物结合颗粒的微流体悬浮液。 通过将悬浮液暴露于物理力，磁力或其组合，使至少一种分析物结合的颗粒与流体分离。 使用至少一种分析物结合的颗粒来改变溶液的分光光度特性。 用光学检测系统测量改变的分光光度特性。