公开(公告)号：US10940005B2

公开(公告)日：2021-03-09

申请号：US15953220

申请日：2018-04-13

Applicant: Edwards Lifesciences Corporation

Inventor： Eric Robert Dixon ,  Jensen Chen ,  Guillermo W. Moratorio ,  Hengchu Cao ,  Douglas Thomas Dominick ,  Sergio Delgado

IPC: A61F2/24 ,  A61B17/128 ,  A61B17/122 ,  A61B17/00 ,  A61B17/064 ,  A61F2/00

Abstract: An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles are extendable from a folded closed position to an open position. A clasp is attached to each of the paddles. Each clasp has a fixed arm attached to the inner portion of the paddle and a moveable arm having a barbed portion. A hinge portion connects the fixed arm to the moveable arm. A cover wraps around at least a portion of the moveable arm of the clasp. At least one actuation suture is attached to the cover.

公开(公告)号：US10898327B2

公开(公告)日：2021-01-26

申请号：US15953283

申请日：2018-04-13

Applicant: Edwards Lifesciences Corporation

Inventor： Eric Robert Dixon ,  Jensen Chen ,  Guillermo W. Moratorio ,  Hengchu Cao ,  Douglas Thomas Dominick ,  Sergio Delgado

IPC: A61F2/24 ,  A61B17/128 ,  A61B17/122 ,  A61B17/00 ,  A61B17/064 ,  A61F2/00

Abstract: An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles have an outer portion and an inner portion. The paddles are extendable from a folded closed position to an open position. A clasp is attached to each of the plurality of paddles. The clasps have a concave upper surface and a convex lower surface. The clasps include a fixed arm attached to the inner portion of the paddle, a moveable arm having a barbed portion, and a hinge portion connecting the fixed arm to the moveable arm.

公开(公告)号：US20180296329A1

公开(公告)日：2018-10-18

申请号：US15914143

申请日：2018-03-07

Applicant: Edwards Lifesciences Corporation

Inventor： Eric Robert Dixon ,  Jensen Chen ,  Guillermo W. Moratorio ,  Hengchu Cao ,  Douglas Thomas Dominick ,  Sergio Delgado ,  Lauren R. Freschauf

IPC: A61F2/24

Abstract: An implantable prosthetic has a coaption portion, paddles, and clasps. The paddles are extendable from a folded closed position to an open position. A clasp has a fixed arm attached to the paddle. The clasps also have a moveable arm having a barbed portion and an end that is rounded. A hinge portion connects the fixed arm to the moveable arm.

公开(公告)号：US11234822B2

公开(公告)日：2022-02-01

申请号：US16593373

申请日：2019-10-04

Applicant: Edwards Lifesciences Corporation

Inventor： Eric Robert Dixon ,  Sergio Delgado ,  Jensen Chen ,  Guillermo W. Moratorio ,  Hengchu Cao ,  Douglas Thomas Dominick

IPC: A61F2/24 ,  A61B17/128 ,  A61B17/122 ,  A61B17/00 ,  A61B17/064 ,  A61F2/00

Abstract: An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles are moveable from a closed position to an open position. The clasps are also moveable from an open position to a closed position. The implantable prosthetic device can be used to repair a native valve, such as a native mitral valve. Other embodiments are also described.

公开(公告)号：US10667912B2

公开(公告)日：2020-06-02

申请号：US15946604

申请日：2018-04-05

Applicant: Edwards Lifesciences Corporation

Inventor： Eric Robert Dixon ,  Jensen Chen ,  Guillermo W. Moratorio ,  Hengchu Cao ,  Douglas Thomas Dominick ,  Sergio Delgado ,  Lauren R. Freschauf

IPC: A61F2/24 ,  A61B17/128 ,  A61B17/122 ,  A61B17/00 ,  A61B17/064 ,  A61F2/00

Abstract: An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles are extendable from a folded closed position to an open position. A clasp is attached to each of the paddles. Each clasp has a fixed arm attached to the paddle and a moveable arm having a barbed portion. A hinge portion connects the fixed arm to the moveable arm. The device does not include catch points when the paddles are in the open position and the clasps are in a closed condition.

公开(公告)号：US20200030085A1

公开(公告)日：2020-01-30

申请号：US16593373

申请日：2019-10-04

Applicant: Edwards Lifesciences Corporation

Inventor： Eric Robert Dixon ,  Sergio Delgado ,  Jensen Chen ,  Guillermo W. Moratorio ,  Hengchu Cao ,  Douglas Thomas Dominick

IPC: A61F2/24 ,  A61B17/128 ,  A61B17/122

Abstract: An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles are moveable from a closed position to an open position. The clasps are also moveable from an open position to a closed position. The implantable prosthetic device can be used to repair a naitive valve, such as a native mitral valve. Other embodiments are also described.

公开(公告)号：US20180296334A1

公开(公告)日：2018-10-18

申请号：US15953283

申请日：2018-04-13

Applicant: Edwards Lifesciences Corporation

Inventor： Eric Robert Dixon ,  Jensen Chen ,  Guillermo W. Moratorio ,  Hengchu Cao ,  Douglas Thomas Dominick ,  Sergio Delgado ,  Lauren R. Freschauf

IPC: A61F2/24

Abstract: An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles have an outer portion and an inner portion. The paddles are extendable from a folded closed position to an open position. A clasp is attached to each of the plurality of paddles. The clasps have a concave upper surface and a convex lower surface. The clasps include a fixed arm attached to the inner portion of the paddle, a moveable arm having a barbed portion, and a hinge portion connecting the fixed arm to the moveable arm.

公开(公告)号：US20220008233A1

公开(公告)日：2022-01-13

申请号：US17485239

申请日：2021-09-24

Applicant: Edwards Lifesciences Corporation

Inventor： Nima V. Nia ,  Hengchu Cao ,  Sakyasingh Tripathy ,  Douglas Thomas Dominick ,  Bingquan Su ,  Behnood Miri ,  Zahra Moyedi

IPC: A61F2/93 ,  A61F2/90 ,  A61F2/915

Abstract: Described herein are artificial valves that have a frame and leaflets that grow or expand with a patient. Upon placing the valve inside the patient, the valve expands as the annulus of the patient expands. The frame of the valve is configured to expand which in turn causes the leaflets to expand (e.g., to grow). The valve includes a thin undulating wire embedded inside the leaflets. As the annulus of the patient grows, the frame expands, and as the frame expands, the leaflets grow. The growth or expansion of the leaflets is configured so that the valve continues to operate properly (e.g., the leaflets continue to coapt) with expansion of the annulus. The change in size of the valve can be configured to accommodate changes in size of the annulus from an infant or child to an adult.

公开(公告)号：US11096784B2

公开(公告)日：2021-08-24

申请号：US15909803

申请日：2018-03-01

Applicant: Edwards Lifesciences Corporation

Inventor： Eric Robert Dixon ,  Hengchu Cao ,  Douglas Thomas Dominick ,  Lauren R. Freschauf

IPC: A61F2/24 ,  A61B17/128 ,  A61B17/122 ,  A61B17/00 ,  A61B17/064 ,  A61F2/00

Abstract: An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles are extendable from a folded closed position to an open position. The clasps each have a fixed arm and a plurality of moveable arms each having a barbed portion. A plurality of hinge portions connect the moveable arms to the fixed arm.

公开(公告)号：US11058539B2

公开(公告)日：2021-07-13

申请号：US15910951

申请日：2018-03-02

Applicant: Edwards Lifesciences Corporation

Inventor： Eric Robert Dixon ,  Jensen Chen ,  Guillermo W. Moratorio ,  Hengchu Cao ,  Douglas Thomas Dominick ,  Sergio Delgado

IPC: A61F2/24 ,  A61B17/128 ,  A61B17/122 ,  A61B17/00 ,  A61B17/064 ,  A61F2/00

Abstract: An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles are extendable from a folded closed position to an open position. A clasp is attached to each of the paddles. The clasps have a fixed arm attached to the paddle and a moveable arm. The moveable arm has a barbed portion, a first eyelet, and a second eyelet. The hinge portion connects the fixed arm to the moveable arm. A first intermediate suture loop is attached to the first eyelet and a second intermediate suture loop is attached to the second eyelet. At least one actuation suture is attached to the first and second intermediate suture loops.