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公开(公告)号:US20130131017A1
公开(公告)日:2013-05-23
申请号:US13678578
申请日:2012-11-16
发明人: Tsutomu AKAMA , Terry William Balko , Jean Marie Defauw , Jacob J. Plattner , William Hunter White , Joseph Raymond Winkle , Yong-Kang Zhang , Yasheen Zhou
摘要: This invention provides novel compounds, methods of using the compounds, and pharmaceutical compositions containing the compounds.
摘要翻译: 本发明提供新化合物,使用该化合物的方法和含有这些化合物的药物组合物。
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公开(公告)号:US08546357B2
公开(公告)日:2013-10-01
申请号:US13678578
申请日:2012-11-16
发明人: Tsutomu Akama , Terry William Balko , Jean Marie Defauw , Jacob J. Plattner , William Hunter White , Joseph Raymond Winkle , Yong-Kang Zhang , Yasheen Zhou
IPC分类号: A61K31/69 , A61K31/42 , C07D231/00 , C07D207/40 , C07F5/04
摘要: This invention provides novel compounds, methods of using the compounds, and pharmaceutical compositions containing the compounds.
摘要翻译: 本发明提供新化合物,使用该化合物的方法和含有这些化合物的药物组合物。
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公开(公告)号:US20150353581A1
公开(公告)日:2015-12-10
申请号:US14760208
申请日:2014-03-06
发明人: Tsutomu Akama , Kurt Jarnagin , Jacob J. Plattner , Shon Roland Pulley , William Hunter White , Yong-Kang Zhang , Yasheen Zhou
IPC分类号: C07F5/02
摘要: Provided are compounds useful for controlling endoparasites both in animals and agriculture. Further provided are methods for controlling endoparasite infestations of an animal by administering an effective amount of a compound as described above, or a pharmaceutically acceptable salt thereof, to an animal, as well as formulations for controlling endoparasite infestations using the compounds described above or an acceptable salt thereof, and an acceptable carrier. The claimed compounds are described by the following Markush formula: A typical example for a compound according to above formula is: A typical example for a compound according to above formula is:
摘要翻译: 提供了用于控制动物和农业中的寄生虫的化合物。 进一步提供的是通过向动物施用有效量的上述化合物或其药学上可接受的盐,以及使用上述化合物或可接受的化合物控制内寄生虫侵染的制剂来控制动物的内寄生虫感染的方法 其盐和可接受的载体。 所要求保护的化合物由以下马库什公式描述:根据上式的化合物的典型实例是:根据上式的化合物的典型实例是:
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公开(公告)号:US09617285B2
公开(公告)日:2017-04-11
申请号:US14760208
申请日:2014-03-06
发明人: Tsutomu Akama , Kurt Jarnagin , Jacob J. Plattner , Shon Roland Pulley , William Hunter White , Yong-Kang Zhang , Yasheen Zhou
摘要: Provided are compounds useful for controlling endoparasites both in animals and agriculture. Further provided are methods for controlling endoparasite infestations of an animal by administering an effective amount of a compound as described above, or a pharmaceutically acceptable salt thereof, to an animal, as well as formulations for controlling endoparasite infestations using the compounds described above or an acceptable salt thereof, and an acceptable carrier. The claimed compounds are described by the following Markush formula: A typical example for a compound according to above formula is: A typical example for a compound according to above formula is:
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公开(公告)号:US08853186B2
公开(公告)日:2014-10-07
申请号:US13678576
申请日:2012-11-16
发明人: Tsutomu Akama , Terry William Balko , Jean Marie Defauw , Jacob J. Plattner , William Hunter White , Joseph Raymond Winkle , Yong-Kang Zhang , Yasheen Zhou
摘要: This invention provides novel compounds, methods of using the compounds, and pharmaceutical formulations comprising the compounds.
摘要翻译: 本发明提供新化合物,使用该化合物的方法和包含该化合物的药物制剂。
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公开(公告)号:US20130131016A1
公开(公告)日:2013-05-23
申请号:US13678576
申请日:2012-11-16
发明人: Tsutomu Akama , Terry William Balko , Jean Marie Defauw , Jacob J. Plattner , William Hunter White , Joseph Raymond Winkle , Yong-Kang Zhang , Yasheen Zhou
IPC分类号: C07F5/02
摘要: This invention provides novel compounds, methods of using the compounds, and pharmaceutical formulations comprising the compounds.
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公开(公告)号:US20160115189A1
公开(公告)日:2016-04-28
申请号:US14890743
申请日:2014-06-05
发明人: Shu-Hui Chen , Jean Marie Defauw , Scott Dale Holmstrom , Shon Roland Pulley , William Hunter White , Joseph Raymond Winkle , Wentao Wu , Yang Zhang
IPC分类号: C07H17/08 , A61K31/706 , A61K31/7064 , A61K31/7048 , A61K9/00
CPC分类号: C07H17/08 , A61K9/0014 , A61K31/7048 , A61K31/706 , A61K31/7064 , C07H17/04
摘要: Provided are compounds of formula I useful for controlling parasites both in animals and agriculture. Further provided are methods for controlling parasite infestations of an animal by administering an effective amount of a compound as described above, or a pharmaceutically acceptable salt thereof, to an animal, as well as formulations for controlling parasite infestations using the compounds described above or an acceptable salt thereof, and an acceptable carrier.
摘要翻译: 提供式I化合物,其可用于控制动物和农业中的寄生虫。 进一步提供的是通过向动物施用有效量的上述化合物或其药学上可接受的盐,以及使用上述化合物或可接受的化合物控制寄生虫感染的制剂来控制动物的寄生虫感染的方法 其盐和可接受的载体。
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公开(公告)号:US09255111B2
公开(公告)日:2016-02-09
申请号:US14546590
申请日:2014-11-18
发明人: Zengyun An , Liang Chen , Shuhui Chen , Jean Marie Defauw , Scott Dale Holmstrom , Ping Hu , Chongzhi Tang , William Hunter White , Wentao Wu , Yang Zhang
IPC分类号: C07D495/04 , C07D417/04 , C07D413/04 , A01N43/80 , C07D413/14 , A61K31/422 , A61K31/428 , A61K31/4365 , A61K31/4439 , A61K31/496 , A01N43/90 , A61K31/427
CPC分类号: C07D495/04 , A01N43/80 , A01N43/90 , A61K31/422 , A61K31/427 , A61K31/428 , A61K31/4365 , A61K31/4439 , A61K31/496 , C07D413/04 , C07D413/14 , C07D417/04
摘要: Provided are dihydroisoxazole compounds I useful for controlling parasites both in animals and agriculture. Further provided are methods for controlling parasite infestations of an animal by administering an effective amount of a compound as described above, or a pharmaceutically acceptable salt thereof, to an animal, as well as formulations for controlling parasite infestations using the compounds described above or an acceptable salt thereof, and an acceptable carrier. Also provided are compounds and processes useful for making the dihydroisoxazole compounds. wherein A is
摘要翻译: 提供二氢异恶唑化合物I,其用于控制动物和农业中的寄生虫。 进一步提供的是通过向动物施用有效量的上述化合物或其药学上可接受的盐,以及使用上述化合物或可接受的化合物控制寄生虫感染的制剂来控制动物的寄生虫感染的方法 其盐和可接受的载体。 还提供了可用于制备二氢异恶唑化合物的化合物和方法。 其中A是
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公开(公告)号:US20150045313A1
公开(公告)日:2015-02-12
申请号:US14525939
申请日:2014-10-28
CPC分类号: A01N25/00 , A01N43/22 , A01N45/02 , A61K31/704
摘要: Provided are novel methods and formulations for topically controlling ectoparasite infestations in animals using spinetoram or a pharmaceutically acceptable salt thereof.
摘要翻译: 本发明提供了用于使用旋风索或其药学上可接受的盐来局部控制动物体外寄生虫感染的新方法和制剂。
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公开(公告)号:US08889710B2
公开(公告)日:2014-11-18
申请号:US14137279
申请日:2013-12-20
发明人: Zengyun An , Liang Chen , Shuhui Chen , Jean Marie Defauw , Scott Dale Holmstrom , Ping Hu , Chongzhi Tang , William Hunter White , Wentao Wu , Yang Zhang
IPC分类号: A01N43/80 , A61K31/428 , A61K31/496 , A61K31/422 , C07D413/04 , C07D413/14 , C07D417/04 , C07D495/04 , A61K31/4439 , A61K31/4365
CPC分类号: C07D495/04 , A01N43/80 , A01N43/90 , A61K31/422 , A61K31/427 , A61K31/428 , A61K31/4365 , A61K31/4439 , A61K31/496 , C07D413/04 , C07D413/14 , C07D417/04
摘要: Provided are dihydroisoxazole compounds I useful for controlling parasites both in animals and agriculture. Further provided are methods for controlling parasite infestations of an animal by administering an effective amount of a compound as described above, or a pharmaceutically acceptable salt thereof, to an animal, as well as formulations for controlling parasite infestations using the compounds described above or an acceptable salt thereof, and an acceptable carrier. Also provided are compounds and processes useful for making the dihydroisoxazole compounds. wherein A is
摘要翻译: 提供二氢异恶唑化合物I,其用于控制动物和农业中的寄生虫。 进一步提供的是通过向动物施用有效量的上述化合物或其药学上可接受的盐,以及使用上述化合物或可接受的化合物控制寄生虫感染的制剂来控制动物的寄生虫感染的方法 其盐和可接受的载体。 还提供了可用于制备二氢异恶唑化合物的化合物和方法。 其中A是
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