公开(公告)号：US20240287209A1

公开(公告)日：2024-08-29

申请号：US18570416

申请日：2021-06-18

Applicant: FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V.

Inventor： Kay HETTRICH

IPC: C08B5/14 ,  A61K9/50 ,  B01J13/14

CPC classification number: C08B5/14 ,  A61K9/5036 ,  B01J13/14

Abstract: The present invention relates to a process for preparing polysaccharide sulfates. In the process, a mixture comprising at least one polysaccharide and at least one polar aprotic solvent is provided. The at least one polysaccharide is reacted to form at least one polysaccharide acetate sulfate, wherein at least one sulphating agent, at least one acetylation agent and at least one peroxodisulfate are added to the mixture, the mixture being subsequently subjected to a temperature treatment. The at least one polysaccharide acetate sulfate is separated from the mixture and is reacted to form at least one polysaccharide sulfate. The present invention also relates to a polysaccharide sulfate that can be prepared with the process according to the invention. The present invention further relates to a microcapsule and to a process for preparing a microcapsule.