3-Pyrrolo[b]cyclohexylene-2-dihydroindolinone derivatives and uses thereof
    2.
    发明授权
    3-Pyrrolo[b]cyclohexylene-2-dihydroindolinone derivatives and uses thereof 有权
    3-吡咯并[b]环己基-2-二氢吲哚啉酮衍生物及其用途

    公开(公告)号:US08084621B2

    公开(公告)日:2011-12-27

    申请号:US12517351

    申请日:2007-12-03

    IPC分类号: C07D209/02 A61K31/40

    摘要: 3-pyrrolo[b]cyclohexylene-2-dihydro-indolinone derivatives of formula (I) or their pharmaceutically acceptable salts and uses thereof. The intermediates of formula (II) for preparing the above compounds. The bioassay shows that the above compounds and their pharmaceutically acceptable salts can modulate the activity of protein kinases (PKs), inhibit the activity of tyrosine kinases (PTKs) and inhibit many kinds of tumor cells as well as.

    摘要翻译: 式(I)的3-吡咯并[b]亚环己基-2-二氢 - 二氢吲哚酮衍生物或其药学上可接受的盐和用途。 用于制备上述化合物的式(II)的中间体。 生物测定显示,上述化合物及其药学上可接受的盐可调节蛋白激酶(PK)的活性,抑制酪氨酸激酶(PTK)的活性并抑制多种肿瘤细胞。

    AUTOMATIC SYSTEM AND METHOD TO CONTROL EXERCISE MACHINES
    3.
    发明申请
    AUTOMATIC SYSTEM AND METHOD TO CONTROL EXERCISE MACHINES 审中-公开
    自动化系统及其运行方法

    公开(公告)号:US20160129311A1

    公开(公告)日:2016-05-12

    申请号:US14535321

    申请日:2014-11-07

    申请人: Jie Yang

    发明人: Jie Yang

    IPC分类号: A63B24/00

    摘要: Method and system for operating a fitness exercise equipment are provided. In a preferred embodiment of the present disclosure, a system for operating a fitness exercise equipment comprises a processor and a memory device electronically coupled to the processor, the memory device storing instructions which, when executed by the processor, direct the processor to acquire an initial exercise parameters entered by a user, determine an initial exercise program based on the initial exercise parameters, and initiate movement of the fitness exercise equipment in correspondence with the initial exercise program, where the instruction to acquire the initial exercise parameters comprises instructions to detect commands entered by the user via built-in touch screen of the fitness exercise equipment, wherein instructions to detect commands entered by the user via built-in touch screen comprises detecting a curve drawn by the user on the built-in touch screen.

    摘要翻译: 提供了运行健身运动器材的方法和系统。 在本公开的优选实施例中,用于操作健身锻炼设备的系统包括电子耦合到处理器的处理器和存储设备,所述存储器设备存储指令,所述指令在由所述处理器执行时指示所述处理器获取初始 由用户输入的运动参数,基于初始运动参数确定初始运动程序,并且启动与初始运动程序对应的健身运动设备的移动,其中获取初始运动参数的指令包括用于检测输入的命令的指令 由使用者通过健身运动器材的内置触摸屏,其中通过内置触摸屏检测由用户输入的命令的指令包括检测用户在内置触摸屏上画出的曲线。

    Recombinant β-glucosidase variants for production of soluble sugars from cellulosic biomass
    6.
    发明授权
    Recombinant β-glucosidase variants for production of soluble sugars from cellulosic biomass 有权
    用于从纤维素生物质生产可溶性糖的重组和葡糖苷酶变体

    公开(公告)号:US08685690B2

    公开(公告)日:2014-04-01

    申请号:US13416608

    申请日:2012-03-09

    IPC分类号: C12N9/42 C12P19/02 C12P19/00

    摘要: The invention relates to recombinant expression of a variant form of a fungal C1 strain β-glucosidase. The invention also relates to the generation of fermentable sugars from biomass and the production of biofuels by fermentation of the sugars using genetically modified organisms expressing the β-glucosidase variant. The invention provides methods for producing a fermentable sugar, such as glucose, from cellobiose by contacting cellobiose with a recombinant β-glucosidase variant protein, such as a variant protein secreted by a recombinant host cell into culture medium. Methods of the invention may be used for conversion of a biomass substrate to a fermentable sugar, and ultimately to ethanol or other biofuel.

    摘要翻译: 本发明涉及真菌C1菌株和葡萄糖苷酶的变体形式的重组表达。 本发明还涉及通过使用表达“葡糖苷酶”变体的转基因生物体从生物质产生可发酵糖并通过发酵糖生产生物燃料。 本发明提供了通过将纤维二糖与重组体 - 葡糖苷酶变体蛋白(例如由重组宿主细胞分泌的变体蛋白)接触到培养基中来从纤维二糖生产可发酵糖例如葡萄糖的方法。 本发明的方法可用于将生物质底物转化为可发酵的糖,最终转化为乙醇或其他生物燃料。

    VALVE CURRENT CONTROL METHOD BASED ON MODULAR MULTI-LEVEL CONVERTER
    7.
    发明申请
    VALVE CURRENT CONTROL METHOD BASED ON MODULAR MULTI-LEVEL CONVERTER 审中-公开
    基于模块化多电平转换器的阀门电流控制方法

    公开(公告)号:US20140003101A1

    公开(公告)日:2014-01-02

    申请号:US14005265

    申请日:2011-10-31

    IPC分类号: H02M7/44

    摘要: The present invention relates to valve current control method based on modular multi-level converter, this method includes the control of the low frequency oscillations of the current and that of double frequency harmonic component; For said low frequency oscillations of the current, the control method includes some steps as below: first, calculate the half of the sum of the upper arm current and the lower arm current, it is the valve DC current component, said DC current component is arm circulating current; Secondly, comparing the actual value of the arm circulating current to setting value of that, the error is obtained, after some signal processing, additional output set voltage is obtained. For said the double frequency harmonic component of current, the control method includes some steps as below: firstly, figure out capacitor voltage fluctuation prediction value of the sub module; secondly, the output voltage is divided by the sum of the sub module reference voltage and the capacitor voltage fluctuation prediction value, and get the actual output set number of sub module. This method not only can realize stability of the dynamic performance of the system, but also can suppress the arm double frequency harmonic component, at the same time under the abnormal conditions of the AC system; the valve current has good output characteristics.

    摘要翻译: 本发明涉及基于模块化多电平转换器的阀电流控制方法,该方法包括对电流的低频振荡和双频谐波分量的控制; 对于电流的所述低频振荡,控制方法包括以下步骤:首先计算上臂电流和下臂电流之和的一半,即直流电流分量,直流电流分量为 臂循环电流; 其次,将臂循环电流的实际值与其设定值进行比较,在获得了一些信号处理后,获得了附加的输出设定电压的误差。 对于电流的双频谐波分量,控制方法包括以下几个步骤:首先求出子模块的电容电压波动预测值; 其次,将输出电压除以子模块参考电压和电容器电压波动预测值的总和,得到子模块的实际输出设定数。 该方法不仅可以实现系统动态性能的稳定,而且可以在交流系统的异常情况下同时抑制臂双频谐波分量; 阀门电流具有良好的输出特性。

    MECHANISM FOR FACILITATING POWER EXTENSION SERVICE AT COMPUTING DEVICES
    8.
    发明申请
    MECHANISM FOR FACILITATING POWER EXTENSION SERVICE AT COMPUTING DEVICES 有权
    在计算机设备上实现电力延伸服务的机制

    公开(公告)号:US20130339770A1

    公开(公告)日:2013-12-19

    申请号:US13977681

    申请日:2011-12-21

    IPC分类号: G06F1/32

    摘要: A mechanism is described for facilitating power extension service at computing devices according to one embodiment of the invention. A method of embodiments of the invention includes calculating potential power saving by one or more of a plurality of power-saving techniques supported by a computing device. The calculating includes identifying the one or more of the plurality of power-saving techniques that are available for selection and an expected amount of power to be saved with the one or more of the plurality of power saving techniques. The method may further include generating a list identifying the one or more of the plurality of power-saving techniques and relevant information resulting from the calculation, anddisplaying the list.

    摘要翻译: 描述了根据本发明的一个实施例的用于促进计算设备处的功率扩展服务的机制。 本发明的实施例的方法包括通过由计算设备支持的多个节电技术中的一个或多个来计算潜在的功率节省。 计算包括识别可用于选择的多个节电技术中的一个或多个以及用多个省电技术中的一个或多个来节省的预期功率量。 该方法还可以包括生成识别多个功率节省技术中的一个或多个功能的列表以及从计算得到的相关信息,并显示该列表。

    Method and apparatus for realizing application high availability
    10.
    发明授权
    Method and apparatus for realizing application high availability 有权
    实现应用高可用性的方法和装置

    公开(公告)号:US08433948B2

    公开(公告)日:2013-04-30

    申请号:US13462039

    申请日:2012-05-02

    IPC分类号: G06F11/00

    摘要: A method, apparatus, and computer program product for realizing application high availability are provided. The application is installed on both a first node and a second node, the first node being used as an active node, and the second node being used as a passive node. The method includes: monitoring access operations to files by an application during its execution on the active node; replicating the monitored updates to the file by the application from the active node to a storage device accessible to the passive node if the application performs updates to a file during the access operations; sniffing the execution of the application on the active node; and switching the active node to the second node and initiating the application on the second node in response to sniffing a failure in the execution of the application on the active node.

    摘要翻译: 提供了一种实现应用高可用性的方法,装置和计算机程序产品。 应用程序安装在第一节点和第二节点上,第一节点用作活动节点,第二节点用作被动节点。 该方法包括:在应用程序执行期间监视对文件的访问操作; 如果应用程序在访问操作期间执行对文件的更新,则由应用从主动节点将受监视的更新复制到被动节点可访问的存储设备; 嗅探主动节点上的应用程序的执行; 以及响应于在所述主动节点上执行所述应用程序的嗅探响应,将所述活动节点切换到所述第二节点并且发起所述第二节点上的应用。