-
公开(公告)号:US20150258082A1
公开(公告)日:2015-09-17
申请号:US14657584
申请日:2015-03-13
申请人: Francesco Parlati , Mirna L. Rodriguez , Matthew I. Gross , Terri L. Davis , Jim Li , Lijing Chen , Bindu Goyal , Guy Laidig , Timothy F. Stanton , Eric B. Sjogren
发明人: Francesco Parlati , Mirna L. Rodriguez , Matthew I. Gross , Terri L. Davis , Jim Li , Lijing Chen , Bindu Goyal , Guy Laidig , Timothy F. Stanton , Eric B. Sjogren
IPC分类号: A61K31/454 , A61K31/4402 , A61K31/573
CPC分类号: A61K31/454 , A61K31/4035 , A61K31/4402 , A61K31/501 , A61K31/517 , A61K31/573 , A61K45/06 , A61K2300/00
摘要: The invention relates to methods of treating cancer, myeloproliferative disorders or immunological diseases with a combination of an immunomodulatory agent and a glutaminase inhibitor. The invention further relates to methods of treating cancer, myeloproliferative disorders, or immunological diseases that are resistant to one or more immunomodulatory agents.
摘要翻译: 本发明涉及通过免疫调节剂和谷氨酰胺酶抑制剂的组合治疗癌症,骨髓增生性疾病或免疫疾病的方法。 本发明还涉及治疗对一种或多种免疫调节剂具有抗性的癌症,骨髓增生性疾病或免疫疾病的方法。