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公开(公告)号:US20180078541A1
公开(公告)日:2018-03-22
申请号:US15710249
申请日:2017-09-20
申请人: GRÜNENTHAL GMBH
发明人: FLORIAN JAKOB , SONJA NORDHOFF , DAVID RIDER , MARKUS WAGENER , GREGOR BAHRENBERG , TORSTEN DUNKERN
IPC分类号: A61K31/451 , A61K31/17 , A61K31/085 , A61K31/03
CPC分类号: A61K31/451 , A61K31/03 , A61K31/085 , A61K31/17 , A61K31/445 , A61K31/45 , A61K31/4545 , C07D211/16 , C07D211/56 , C07D211/94 , C07D401/12
摘要: The present invention relates to a compound according to general formula (I) which acts as a modulator of FPR2 and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by FPR2.
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公开(公告)号:US20150166505A1
公开(公告)日:2015-06-18
申请号:US14574447
申请日:2014-12-18
申请人: GRÜNENTHAL GMBH
IPC分类号: C07D401/04 , C07D405/14 , A61K31/4439 , C07D413/14 , C07D401/14 , A61K31/444
CPC分类号: C07D401/04 , A61K31/4439 , A61K31/444 , C07D401/14 , C07D405/14 , C07D413/14
摘要: The invention relates to pyrazolyl-based carboxamide compounds useful as ICRAC inhibitors, to pharmaceutical compositions containing these compounds and to methods of using these compounds for the treatment and/or prophylaxis of diseases and/or disorders, in particular inflammatory diseases and/or inflammatory disorders.
摘要翻译: 本发明涉及可用作ICRAC抑制剂的基于吡唑基的羧酰胺化合物,含有这些化合物的药物组合物以及使用这些化合物治疗和/或预防疾病和/或病症,特别是炎性疾病和/或炎症性疾病的方法 。
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