公开(公告)号：US07799913B2

公开(公告)日：2010-09-21

申请号：US10495049

申请日：2002-11-25

申请人： Gary A. Rogers ,  Matthew Allan ,  Clayton Harris ,  Jianjie Huang ,  Christopher M. Marrs ,  Rudolf Mueller ,  Stanislaw Rachwal

发明人： Gary A. Rogers ,  Matthew Allan ,  Clayton Harris ,  Jianjie Huang ,  Christopher M. Marrs ,  Rudolf Mueller ,  Stanislaw Rachwal

IPC分类号： C07D265/12 ,  C07D265/14 ,  C07D491/04 ,  C07D498/04 ,  C07D513/04 ,  C07D515/04 ,  A61K31/536 ,  A61K31/5365 ,  A61P25/18

CPC分类号： C07D265/22 ,  C07D413/06

摘要： This invention related to the prevention and treatment of cerebral insufficiency, including enhancement of receptor functioning in synapses in brain networks responsible for higher order behaviors. These brain networks are involved in cognitive abilities related to memory impairment, such as is observed In a variety of dementias, and in imbalances in neuronal activity between different brain regions, as is suggested in disorders such as Parkinson′s disease, schizophrenia and affective disorders. In a particular aspect, the present invention relates to compounds useful for treatment of such conditions and methods of using these compounds for such treatment.

摘要翻译： 本发明涉及预防和治疗脑功能不全，包括增强负责高阶行为的脑网络突触中的受体功能。 这些脑网络涉及与记忆障碍相关的认知能力，例如在各种痴呆中观察到的，以及在不同脑区域之间的神经元活动的不平衡，如帕金森病，精神分裂症和情感障碍 。 在一个具体方面，本发明涉及可用于治疗这些病症的化合物和使用这些化合物进行这种治疗的方法。

公开(公告)号：US20070218804A1

公开(公告)日：2007-09-20

申请号：US11687523

申请日：2007-03-16

申请人： Matthew Allan ,  Christopher O'Toole

发明人： Matthew Allan ,  Christopher O'Toole

IPC分类号： A01K47/00

CPC分类号： A01K67/033 ,  A01K47/00 ,  A01K49/00

摘要： An apparatus for providing solitary bees for pollination, comprising a bee nest and a portable on-site incubator. The bee nest can comprise a plurality of corrugated sheets, each sheet comprising a plurality of flutes. When the sheets are stacked together, the flutes form cavities arranged in a tessellating pattern. The portable incubator can comprise a chamber for holding dormant adult bees, an opening providing access to the chamber, a passage for exiting of bees from the chamber, means for heating the chamber, means for controlling chamber temperature, and a power supply. Dormant adult bees placed in the incubator are stimulated into activity and leave the incubator. Female bees that leave later lay eggs in the bee nest.

摘要翻译： 一种用于提供用于授粉的蜂蜜的装置，包括蜂巢和便携式现场孵化器。 蜂巢可以包括多个波纹片，每个片包括多个凹槽。 当片材堆叠在一起时，凹槽形成为以镶嵌图案布置的空腔。 便携式培养箱可以包括用于保持休眠的成年蜜蜂的腔室，提供进入腔室的开口，用于从腔室排出蜜蜂的通道，用于加热腔室的装置，用于控制腔室温度的装置和电源。 孵化器中的休眠成虫被刺激活动并离开孵化器。 离开的雌性蜜蜂会在蜜蜂巢中产卵。