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公开(公告)号:US09277957B2
公开(公告)日:2016-03-08
申请号:US13586422
申请日:2012-08-15
CPC分类号: A61B18/1206 , A61B18/1492 , A61B2018/00613 , A61B2018/00791 , A61B2018/00815 , A61B2018/00982 , A61B2018/126
摘要: An electrosurgical system may generally first and second electrodes coupled to an energy source operative to generate and deliver pulses of a biphasic radio frequency (RF) waveform to treat undesirable tissue in a patient. The pulses may induce non-thermal cell death in the patient's tissue while causing no or minimal muscle contractions in the treated patient. The pulses may be grouped in bursts wherein the pulses within a burst repeat at a particular pulse frequency.
摘要翻译: 电外科系统通常可以耦合到能量源的第一和第二电极,其操作以产生和递送双相射频(RF)波形的脉冲,以治疗患者中的不希望的组织。 脉冲可能在患者组织中引起非热细胞死亡,同时在治疗的患者中没有或最小的肌肉收缩。 脉冲可以以脉冲串分组,其中突发脉冲在特定脉冲频率下重复。
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公开(公告)号:US20140052126A1
公开(公告)日:2014-02-20
申请号:US13586422
申请日:2012-08-15
CPC分类号: A61B18/1206 , A61B18/1492 , A61B2018/00613 , A61B2018/00791 , A61B2018/00815 , A61B2018/00982 , A61B2018/126
摘要: An electrosurgical system may generally first and second electrodes coupled to an energy source operative to generate and deliver pulses of a biphasic radio frequency (RF) waveform to treat undesirable tissue in a patient. The pulses may induce non-thermal cell death in the patient's tissue while causing no or minimal muscle contractions in the treated patient. The pulses may be grouped in bursts wherein the pulses within a burst repeat at a particular pulse frequency.
摘要翻译: 电外科系统通常可以耦合到能量源的第一和第二电极,其操作以产生和递送双相射频(RF)波形的脉冲,以治疗患者中的不希望的组织。 脉冲可能在患者组织中引起非热细胞死亡,同时在治疗的患者中没有或最小的肌肉收缩。 脉冲可以以脉冲串分组,其中突发脉冲在特定脉冲频率下重复。
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公开(公告)号:US10314649B2
公开(公告)日:2019-06-11
申请号:US13565307
申请日:2012-08-02
摘要: A surgical instrument, such as an electrical ablation device, includes an elongate member having therealong disposed a first electrode extending along an axis. A first expandable portion extends along the axis and defines a first perimeter of the first electrode and has an associated first diameter with respect to the axis. The first expandable portion includes a first framework selectively expandable to transition the first expandable portion from a contracted state to an expanded state. The first framework is selectively contractible to transition the first expandable portion from the expanded state to the contracted state. When the first framework is expanded, the first diameter is expanded and the first expandable portion is transitioned from the contracted state to the expanded state. When the first framework is contracted, the first diameter is contracted and the first expandable portion is transitioned from the expanded state to the contracted state.
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公开(公告)号:US20140052216A1
公开(公告)日:2014-02-20
申请号:US13586439
申请日:2012-08-15
IPC分类号: A61N1/00
CPC分类号: A61N1/0468 , A61B5/01 , A61B17/064 , A61B18/1477 , A61B2017/00084 , A61B2017/00154 , A61B2018/00613 , A61B2018/00642 , A61B2018/00791 , A61N1/326 , A61N1/327
摘要: A method for promoting wound healing at a wound site includes subjecting the wound site to electrical pulses to promote wound healing during at least one of the stages of wound healing. The method may further include closing the wound site by sutures or staples prior to and or after applying the electrical pulses that promote wound healing.
摘要翻译: 用于促进伤口部位的伤口愈合的方法包括在伤口愈合的至少一个阶段中对创伤部位进行电脉冲以促进伤口愈合。 该方法可以进一步包括在施加促进伤口愈合的电脉冲之前和之后通过缝合线或缝钉来闭合伤口部位。
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公开(公告)号:US09545290B2
公开(公告)日:2017-01-17
申请号:US13561945
申请日:2012-07-30
CPC分类号: A61B90/11 , A61B18/1206 , A61B18/14 , A61B90/06 , A61B2017/00154 , A61B2018/00577 , A61B2018/00613 , A61B2018/00922 , A61B2018/143 , A61B2018/1475 , A61B2090/064
摘要: A device for guiding electrodes relative to a tissue treatment region. The device can comprise a body have a plurality of passages therethrough. Each passage can axially restrain an electrode positioned therein. When each electrode is axially restrained in a passage, the distal ends of the electrodes can be spaced a predetermined distance apart. Further, the electrodes can be held in a parallel or substantially parallel alignment when axially retained in the passages. The predetermined distance between the electrodes can correspond to a treatment distance in a tissue treatment region and the distal ends of the electrodes can be operably structured to conduct current therebetween when at least one of electrodes is energized by an energy source.
摘要翻译: 用于相对于组织处理区域引导电极的装置。 该装置可以包括具有穿过其中的多个通道的主体。 每个通道可以轴向限制位于其中的电极。 当每个电极轴向地限制在通道中时,电极的远端可以间隔开预定距离。 此外,当轴向保持在通道中时,电极可以保持平行或基本上平行的对准。 电极之间的预定距离可以对应于组织治疗区域中的治疗距离,并且当电极中的至少一个被能量源激励时,电极的远端可以可操作地构造成在其间传导电流。
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公开(公告)号:US20140031813A1
公开(公告)日:2014-01-30
申请号:US13561945
申请日:2012-07-30
IPC分类号: A61B18/14
CPC分类号: A61B90/11 , A61B18/1206 , A61B18/14 , A61B90/06 , A61B2017/00154 , A61B2018/00577 , A61B2018/00613 , A61B2018/00922 , A61B2018/143 , A61B2018/1475 , A61B2090/064
摘要: A device for guiding electrodes relative to a tissue treatment region. The device can comprise a body have a plurality of passages therethrough. Each passage can axially restrain an electrode positioned therein. When each electrode is axially restrained in a passage, the distal ends of the electrodes can be spaced a predetermined distance apart. Further, the electrodes can be held in a parallel or substantially parallel alignment when axially retained in the passages. The predetermined distance between the electrodes can correspond to a treatment distance in a tissue treatment region and the distal ends of the electrodes can be operably structured to conduct current therebetween when at least one of electrodes is energized by an energy source.
摘要翻译: 用于相对于组织处理区域引导电极的装置。 该装置可以包括具有穿过其中的多个通道的主体。 每个通道可以轴向限制位于其中的电极。 当每个电极轴向地限制在通道中时,电极的远端可以间隔开预定距离。 此外,当轴向保持在通道中时,电极可以保持平行或基本上平行的对准。 电极之间的预定距离可以对应于组织治疗区域中的治疗距离,并且当电极中的至少一个被能量源激励时,电极的远端可以可操作地构造成在其间传导电流。
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公开(公告)号:US20110160514A1
公开(公告)日:2011-06-30
申请号:US12651181
申请日:2009-12-31
申请人: Gary L. Long , David N. Plescia , Peter K. Shires
发明人: Gary L. Long , David N. Plescia , Peter K. Shires
CPC分类号: A61B18/1492 , A61B18/02 , A61B18/1206 , A61B18/1477 , A61B18/16 , A61B2018/00136 , A61B2018/00214 , A61B2018/0022 , A61B2018/00482 , A61B2018/00494 , A61B2018/00547 , A61B2018/00577 , A61B2018/00613 , A61B2018/00642 , A61B2018/00928 , A61B2018/00982 , A61B2018/0212 , A61B2018/046 , A61B2018/1226 , A61B2018/1253 , A61B2018/126 , A61B2018/1266 , A61B2018/1405 , A61B2018/1425 , A61B2018/1472 , A61B2218/002 , A61M2205/054
摘要: A variety of electrical ablation apparatuses and methods are disclosed. In one embodiment, an ablation apparatus includes an injector catheter electrode having a proximal end configured to couple to an energy source and a fluid source. A distal end of the injector catheter defines an injection needle and defines an electrically conductive hollow channel for communicating a fluid from the fluid source to a treatment site. A balloon electrode is in fluid communication with a balloon catheter. The balloon catheter has a proximal end configured to couple to the energy source and the fluid source and a distal end configured to inflate the balloon electrode.
摘要翻译: 公开了各种电气消融装置和方法。 在一个实施例中,消融装置包括注射器导管电极,其具有被配置为耦合到能量源和流体源的近端。 注射器导管的远端限定注射针并且限定用于将流体从流体源传递到治疗部位的导电中空通道。 球囊电极与球囊导管流体连通。 气囊导管具有被配置为联接到能量源和流体源的近端,以及构造成使球囊电极膨胀的远端。
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公开(公告)号:US09314620B2
公开(公告)日:2016-04-19
申请号:US13036908
申请日:2011-02-28
申请人: Gary L. Long , David N. Plescia , Gregory J. Bakos
发明人: Gary L. Long , David N. Plescia , Gregory J. Bakos
CPC分类号: A61N1/327 , A61B18/1206 , A61B18/1492 , A61B18/1815 , A61B2018/00613 , A61B2018/00642 , A61B2018/00672 , A61B2018/00678 , A61B2018/00708 , A61B2018/00791 , A61B2090/064
摘要: An electrical ablation device may generally comprise first and second electrodes coupled to an energy source operative to generate and deliver a first sequence of electrical pulses and a second sequence of electrical pulses to tissue having a necrotic threshold, wherein the first sequence of electrical pulses delivers a first energy dose that is less than the necrotic threshold to induce thermal heating in the tissue and the second sequence of electrical pulses delivers a second energy dose equal to or greater than the necrotic threshold to induce cell necrosis in the tissue by irreversible electroporation. The first sequence of electrical pulses may each be independently characterized by a first amplitude, a first pulse width, and a first frequency. The second sequence of electrical pulses may be characterized by a second amplitude, a second pulse width, and a second frequency.
摘要翻译: 电消融装置通常可以包括耦合到能量源的第一和第二电极,其能够产生并递送电脉冲的第一序列和第二电脉冲序列到具有坏死阈值的组织,其中电脉冲的第一序列递送 第一能量剂量小于坏死阈值以诱导组织中的热加热,第二电脉冲序列传递等于或大于坏死阈值的第二能量剂量,以通过不可逆电穿孔诱导组织中的细胞坏死。 电脉冲的第一序列可以各自独立地以第一幅度,第一脉冲宽度和第一频率为特征。 电脉冲的第二序列可以由第二幅度,第二脉冲宽度和第二频率表征。
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公开(公告)号:US09254169B2
公开(公告)日:2016-02-09
申请号:US13036895
申请日:2011-02-28
申请人: Gary L. Long , David N. Plescia , Gregory J. Bakos
发明人: Gary L. Long , David N. Plescia , Gregory J. Bakos
CPC分类号: A61B18/12 , A61B18/1477 , A61B34/76 , A61B2017/0088 , A61B2018/00333 , A61B2018/00446 , A61B2018/00488 , A61B2018/00494 , A61B2018/005 , A61B2018/00535 , A61B2018/00541 , A61B2018/00547 , A61B2018/00559 , A61B2018/00577 , A61B2018/00613 , A61B2018/00982 , A61B2034/2063 , A61B2090/065 , A61B2090/08021 , A61N1/327
摘要: An ablation apparatus may generally comprise an elongated body having a proximal end and a distal end and a non-conductive tip at the distal end, a conductive sheath at least partially surrounding a portion of the elongated body intermediate the proximal end and the tip, and an electrical conductor electrically connected to the conductive sheath. The ablation apparatus may comprise a first electrode having a first diameter and a plurality of second electrodes each having a second diameter, wherein the first diameter is greater than the second diameter. Methods of using the ablation apparatus are also described.
摘要翻译: 消融装置通常可以包括细长主体,其具有近端和远端以及在远端处的非导电尖端,导电护套至少部分地围绕在近端和尖端之间的细长体的一部分,以及 电导体,电连接到导电护套。 消融装置可以包括具有第一直径的第一电极和各自具有第二直径的多个第二电极,其中第一直径大于第二直径。 还描述了使用消融装置的方法。
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公开(公告)号:US20120220998A1
公开(公告)日:2012-08-30
申请号:US13036908
申请日:2011-02-28
申请人: Gary L. Long , David N. Plescia , Gregory J. Bakos
发明人: Gary L. Long , David N. Plescia , Gregory J. Bakos
IPC分类号: A61B18/14
CPC分类号: A61N1/327 , A61B18/1206 , A61B18/1492 , A61B18/1815 , A61B2018/00613 , A61B2018/00642 , A61B2018/00672 , A61B2018/00678 , A61B2018/00708 , A61B2018/00791 , A61B2090/064
摘要: An electrical ablation device may generally comprise first and second electrodes coupled to an energy source operative to generate and deliver a first sequence of electrical pulses and a second sequence of electrical pulses to tissue having a necrotic threshold, wherein the first sequence of electrical pulses delivers a first energy dose that is less than the necrotic threshold to induce thermal heating in the tissue and the second sequence of electrical pulses delivers a second energy dose equal to or greater than the necrotic threshold to induce cell necrosis in the tissue by irreversible electroporation. The first sequence of electrical pulses may each be independently characterized by a first amplitude, a first pulse width, and a first frequency. The second sequence of electrical pulses may be characterized by a second amplitude, a second pulse width, and a second frequency.
摘要翻译: 电消融装置通常可以包括耦合到能量源的第一和第二电极,其能够产生并递送电脉冲的第一序列和第二电脉冲序列到具有坏死阈值的组织,其中电脉冲的第一序列递送 第一能量剂量小于坏死阈值以诱导组织中的热加热,第二电脉冲序列传递等于或大于坏死阈值的第二能量剂量,以通过不可逆电穿孔诱导组织中的细胞坏死。 电脉冲的第一序列可以各自独立地以第一幅度,第一脉冲宽度和第一频率为特征。 电脉冲的第二序列可以由第二幅度,第二脉冲宽度和第二频率表征。
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