公开(公告)号：US4960781A

公开(公告)日：1990-10-02

申请号：US481780

申请日：1990-02-16

申请人： Graham Holmwood ,  Wolfgang Kramer ,  Erik Regel ,  Hans L. Elbe ,  Karl H. Buchel ,  Stefan Dutzmann ,  Wilhelm Brandes ,  Paul Reinecke

发明人： Graham Holmwood ,  Wolfgang Kramer ,  Erik Regel ,  Hans L. Elbe ,  Karl H. Buchel ,  Stefan Dutzmann ,  Wilhelm Brandes ,  Paul Reinecke

IPC分类号： A01N43/653 ,  C07D231/12 ,  C07D231/16 ,  C07D249/08 ,  C07D249/10 ,  C07D403/06 ,  C07D405/06 ,  C07D521/00

CPC分类号： C07D231/12 ,  A01N43/653 ,  C07D233/56 ,  C07D249/08

摘要： Fungicidal bisazolyl-hydroxyalkyl derivatives of the formula ##STR1## in which Ar stands for optionally substituted aryl,X stands for a grouping --CH.sub.2 CH.sub.2 --, --OCH.sub.2 --, --SCH.sub.2 -- or --SH.dbd.CH--,Y stands for a nitrogen atom or the grouping CR.sup.3,R.sup.1, R.sup.2 and R.sup.3 stand for hydrogen, halogen or methyl, andn stands for the numbers 0, 1 or 2,and acid addition salts and metal salt complexes thereof. Intermediates of the formulas ##STR2## are also new.

摘要翻译： 式（I）的杀真菌双唑基 - 羟烷基衍生物，其中Ar代表任选取代的芳基，X代表基团-CH 2 CH 2 - ， - OCH 2 - ， - CH 2 - 或-SH = CH-，Y代表 氮原子或分组CR 3，R 1，R 2和R 3代表氢，卤素或甲基，n代表数字0,1或2及其酸加成盐和金属盐络合物。 （IMAG）（II）（IV）（VI）的中间体也是新的。

公开(公告)号：US4639462A

公开(公告)日：1987-01-27

申请号：US547807

申请日：1983-11-01

申请人： Wolfgang Kramer ,  Karl H. Buchel ,  Graham Holmwood ,  Erik Regel ,  Paul Reinecke ,  Wilhelm Brandes

发明人： Wolfgang Kramer ,  Karl H. Buchel ,  Graham Holmwood ,  Erik Regel ,  Paul Reinecke ,  Wilhelm Brandes

IPC分类号： A01N43/50 ,  A01N43/653 ,  C07C45/56 ,  C07C49/185 ,  C07D249/08 ,  C07D317/26 ,  C07D319/06 ,  C07D405/06 ,  C07D405/14 ,  C07D407/04 ,  C07D407/06 ,  C07D521/00 ,  C07D233/60

CPC分类号： C07D231/12 ,  A01N43/50 ,  A01N43/653 ,  C07C45/56 ,  C07C49/185 ,  C07D233/56 ,  C07D249/08 ,  C07D317/26 ,  C07D319/06 ,  C07D407/04 ,  C07D407/06

摘要： Heterocyclyl-hydroxyalkyl-azolyl derivatives of the formula ##STR1## in which Az represents 1,2,4-triazol-1-yl, 1,2,4-triazol-4-yl or imidazol-1-yl,Het represents optionally substituted dioxolanyl or 1,3-dioxanyl,R represents alkyl, optionally substituted phenyl, optionally substituted phenylalkyl, optionally substituted phenoxyalky, optionally substituted phenylthioalkyl, optionally substituted cycloalkyl, optionally substituted cycloalkylalkyl, alkenyl, optionally substituted phenylalkenyl, optionally substituted cyclohexylalkenyl, furyl, naphthyloxymethyl or azolylalkyl,R' represents hydrogen, optionally substituted alkyl or alkenyl andn represents the number 0 or 1,or addition products thereof with acids or metal salts, which possess fungicidal activity.

摘要翻译： 其中Az表示1,2,4-三唑-1-基，1,2,4-三唑-4-基或咪唑-1-基的式（I）的杂环基 - 羟基烷基 - 唑基衍生物，Het 任选取代的苯氧基烷基，任选取代的苯硫基烷基，任选取代的环烷基，任选取代的环烷基烷基，烯基，任选取代的苯基烯基，任选取代的环己基烯基，呋喃基 ，萘氧基甲基或唑基烷基，R'表示氢，任选取代的烷基或链烯基，n表示0或1，或其与具有杀真菌活性的酸或金属盐的加成产物。

公开(公告)号：US4935049A

公开(公告)日：1990-06-19

申请号：US255207

申请日：1988-10-07

申请人： Wolfgang Kramer ,  Erik Regel ,  Karl H. Buchel ,  Stefan Dutzmann ,  Wilhelm Brandes ,  Klaus Lurssen

发明人： Wolfgang Kramer ,  Erik Regel ,  Karl H. Buchel ,  Stefan Dutzmann ,  Wilhelm Brandes ,  Klaus Lurssen

IPC分类号： A01N43/78 ,  A01N43/84 ,  C07D277/24 ,  C07D277/28 ,  C07D277/42 ,  C07D417/06 ,  C07D417/14 ,  C07D521/00

CPC分类号： C07D231/12 ,  A01N43/78 ,  C07D233/56 ,  C07D249/08 ,  C07D277/24 ,  C07D277/28

摘要： New substituted azolylmethylcarbinols of the formula ##STR1## in which Ar stands for optionally substituted aryl,Z stands for nitrogen or an CH group andR stands for alkyl, dialkylaminoalkyl, alkenyl, alkinyl, alkoxyalkyl, optionally substituted aralkyl, optionally substituted aryloxyalkyl, optionally substituted aryl or a radical of the formula ##STR2## whereinR.sup.1 stands for hydrogen, alkyl, alkenyl, alkinyl or cycloalkyl andR.sup.2 stands for hydrogen, alkyl, alkoxyalkyl, alkenyl, alkinyl, cycloalkyl, cycloalkylalkyl, for optionally substituted aryl or for optionally substituted aralkyl, orR.sup.1 and R.sup.2 together with the nitrogen atom to which they are bonded stand for an optionally substituted heterocyclic ring which cna optionally contain further heteroatoms,and acid addition salts and metal salt complexes thereof, and the use of the novel compounds as fungicides and plant growth regulators.

摘要翻译： 式（I）的新取代的吡唑甲基甲醇其中Ar代表任选取代的芳基，Z代表氮或CH基团，R代表烷基，二烷基氨基烷基，烯基，炔基，烷氧基烷基，任选取代的芳烷基，任选取代的芳氧基烷基 ，任选取代的芳基或下式的基团其中R1代表氢，烷基，烯基，炔基或环烷基，R2代表氢，烷基，烷氧基烷基，烯基，炔基，环烷基，环烷基烷基，任选取代的芳基或 任选取代的芳烷基，或R 1和R 2与它们所键合的氮原子一起代表任选取代的杂环，其任选地含有其它杂原子，以及其酸加成盐和金属盐络合物，以及将新化合物用作 杀真菌剂和植物生长调节剂。

公开(公告)号：US4904296A

公开(公告)日：1990-02-27

申请号：US121552

申请日：1987-11-17

申请人： Graham Holmwood ,  Erik Regel ,  Gerhard Jager ,  Karl H. Buchel ,  Klaus Lurssen ,  Paul-Ernst Frohberger ,  Wilhelm Brandes ,  Volker Paul

发明人： Graham Holmwood ,  Erik Regel ,  Gerhard Jager ,  Karl H. Buchel ,  Klaus Lurssen ,  Paul-Ernst Frohberger ,  Wilhelm Brandes ,  Volker Paul

IPC分类号： A01N43/50 ,  A01N43/653 ,  C07D233/60 ,  C07D249/08 ,  C07D303/22 ,  C07D303/34 ,  C07D405/06 ,  C07D521/00

CPC分类号： C07D303/22 ,  A01N43/50 ,  A01N43/653 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08

摘要： Compounds which are substituted 1-hydroxyalkylazolyl derivatives of the general formula ##STR1## in which A represents a nitrogen atom or a CH group,B represents oxygen, sulphur or a CH.sub.2 group,R represents substituted alkyl, and, in the case in which B represents sulphur, also represents an unsubstituted alkyl, optionally substituted cycloalkyl or optionally substituted phenyl group, Z represents a halogen atom or an alkyl, cycloalkyl, alkoxy, alkylthio, halogenoalkyl, halogenoalkoxy, halogenoalkylthio, optionally substituted phenyl, optionally substituted phenoxy, optionally substituted phenylalkyl or optionally substituted phenylalkoxy group, andm is 0, 1, 2 or 3,and the acid addition salts and metal salt complexes thereof, are new, are prepared as described and find use as fungicides and plant growth regulators.

公开(公告)号：US4868196A

公开(公告)日：1989-09-19

申请号：US859276

申请日：1986-05-02

申请人： Graham Holmwood ,  Erik Regel ,  Gerhard Jager ,  Karl H. Buchel ,  Paul-Ernst Frohberger ,  Wilhelm Brandes ,  Klaus Lurssen

发明人： Graham Holmwood ,  Erik Regel ,  Gerhard Jager ,  Karl H. Buchel ,  Paul-Ernst Frohberger ,  Wilhelm Brandes ,  Klaus Lurssen

IPC分类号： A01N43/50 ,  A01N43/653 ,  C07D233/60 ,  C07D249/08 ,  C07D521/00

CPC分类号： C07D231/12 ,  A01N43/50 ,  A01N43/653 ,  C07D233/56 ,  C07D249/08

摘要： Compounds which are ether derivatives of substituted 1-hydroxyalkyl-azoles, of the general formula ##STR1## in which A represents a nitrogen atom or a CH group,B represents oxygen, sulphur or a CH.sub.2 group,R.sup.1 represents a substituted alkyl, optionally substituted cycloalkyl or optionally substituted phenyl radical or, if either A represents a nitrogen atom, or if A represents the CH group and at the same B represents oxygen or sulphur, R.sup.1 also represents an unsubstituted alkyl radical,R.sup.2 represents an alkyl, alkenyl, alkinyl, optionally substituted phenyl or optionally substituted benzyl radical,Z represents a halogen atom or an alkyl, cycloalkyl, alkoxy, alkylthio, halogenoalkyl, halogenoalkoxy, halogenoalkylthio, optionally substituted phenoxy, optionally substituted phenylalkyl or optionally substituted phenylalkoxy radical andm is 0, 1, 2 or 3,and acid addition salts and metal salt complexes thereof, are novel, are prepared as described, and find use as fungicides and as agents for regulating plant growth.

摘要翻译： 作为其中A表示氮原子或CH基团的通式为：（I）的取代的1-羟基烷基 - 唑的醚衍生物的化合物，B表示氧，硫或CH2基，R1表示取代的烷基 ，任选取代的环烷基或任选取代的苯基，或者如果A表示氮原子，或者如果A表示CH基团，而相同的B表示氧或硫，则R1还表示未取代的烷基，R2表示烷基，烯基 烷氧基，烷硫基，卤代烷基，卤代烷氧基，卤代烷硫基，任选取代的苯氧基，任意取代的苯基烷基或任意取代的苯基烷氧基，m为0， 1,2或3及其酸加成盐和金属盐络合物是新颖的，按照所述制备，可用作杀真菌剂和如年龄 用于调节植物生长。

公开(公告)号：US4797499A

公开(公告)日：1989-01-10

申请号：US895089

申请日：1986-08-11

申请人： Graham Holmwood ,  Erik Regel ,  Gerhard Jager ,  Karl H. Buchel ,  Klaus Lurssen ,  Paul-Ernst Frohberger ,  Wilhelm Brandes ,  Volker Paul

发明人： Graham Holmwood ,  Erik Regel ,  Gerhard Jager ,  Karl H. Buchel ,  Klaus Lurssen ,  Paul-Ernst Frohberger ,  Wilhelm Brandes ,  Volker Paul

IPC分类号： A01N43/50 ,  A01N43/653 ,  C07D233/60 ,  C07D249/08 ,  C07D303/22 ,  C07D303/34 ,  C07D405/06 ,  C07D521/00 ,  C07D303/08

CPC分类号： C07D303/22 ,  A01N43/50 ,  A01N43/653 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08

摘要： Compounds which are substituted 1-hydroxyalkyl-azolyl derivatives of the general formula ##STR1## in which A represents a nitrogen atom or a CH group,B represents oxygen, sulphur or a CH.sub.2 group,R represents substituted alkyl, and, in the case in which B represents sulphur, also represents an unsubstituted alkyl, optionally substituted cycloalkyl or optionally substituted phenyl group,Z represents a halogen atom or an alkyl, cycloalkyl, alkoxy, alkylthio, halogenoalkyl, halogenoalkoxy, halogenoalkylthio, optionally substituted phenyl, optionally substituted phenoxy, optionally substituted phenylalkyl or optionally substituted phenylalkoxy group, andm is 0, 1, 2 or 3,and the acid addition salts and metal salt complexes thereof, are new, are prepared as described and find use as fungicides and plant growth regulators.

摘要翻译： 化合物，其中A表示氮原子或CH基团，B表示氧，硫或CH2基团，其中R表示取代的烷基，且表示取代的烷基， B代表硫的情况也代表未取代的烷基，任选取代的环烷基或任选取代的苯基，Z代表卤素原子或烷基，环烷基，烷氧基，烷硫基，卤代烷基，卤代烷氧基，卤代烷硫基，任选取代的苯基， 苯氧基，任选取代的苯基烷基或任选取代的苯基烷氧基，m为0,1,2或3，其酸加成盐和金属盐络合物是新的，如上所述制备，可用作杀真菌剂和植物生长调节剂。

公开(公告)号：US5141553A

公开(公告)日：1992-08-25

申请号：US458087

申请日：1983-01-14

申请人： Graham Holmwood ,  Erik Regel ,  Gerhard Jager ,  Karl H. Buchel ,  Paul-Ernst Frohberger ,  Wilhelm Brandes ,  Klaus Lurssen

发明人： Graham Holmwood ,  Erik Regel ,  Gerhard Jager ,  Karl H. Buchel ,  Paul-Ernst Frohberger ,  Wilhelm Brandes ,  Klaus Lurssen

IPC分类号： A01N43/50 ,  A01N43/653 ,  C07D233/60 ,  C07D249/08 ,  C07D521/00

CPC分类号： C07D231/12 ,  A01N43/50 ,  A01N43/653 ,  C07D233/56 ,  C07D249/08

摘要： Compounds which are ether derivatives of substituted 1-hydroxyalkyl-azoles, of the general formula ##STR1## in which A represents a nitrogen atom or a CH group,B represents oxygen, sulphur or a CH.sub.2 group,R.sup.1 represents a substituted alkyl, optionally substituted cycloalkyl or optionally substituted phenyl radical or, if either A represents a nitrogen atom, or if A represents the CH group and at the same B represents oxygen or sulphur, R.sup.1 also represents an unsubstituted alkyl radical,R.sup.2 represents an alkyl, alkenyl, alkinyl, optionally substituted phenyl or optionally substituted benzyl radical,Z represents a halogen atom or an alkyl, cycloalkyl, alkoxy, alkylthio, halogenoalkyl, halogenoalkoxy, halogenoalkylthio, optionally substituted phenoxy, optionally substituted phenylalkyl or optionally substituted phenylalkoxy radical andm is 0, 1, 2 or 3,and acid addition salts and metal salt complexes thereof, are novel, are prepared as described, and fine use as fungicides and as agents for regulating plant growth.

公开(公告)号：US4960456A

公开(公告)日：1990-10-02

申请号：US354329

申请日：1989-05-19

申请人： Graham Holmwood ,  Erik Regel ,  Gerhard Jager ,  Karl H. Buchel ,  Klaus Lurssen ,  Paul-Ernst Frohberger ,  Wilhelm Brandes ,  Volker Paul

发明人： Graham Holmwood ,  Erik Regel ,  Gerhard Jager ,  Karl H. Buchel ,  Klaus Lurssen ,  Paul-Ernst Frohberger ,  Wilhelm Brandes ,  Volker Paul

IPC分类号： A01N43/50 ,  A01N43/653 ,  C07D233/60 ,  C07D249/08 ,  C07D303/22 ,  C07D303/34 ,  C07D405/06 ,  C07D521/00

CPC分类号： C07D303/22 ,  A01N43/50 ,  A01N43/653 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08

摘要： Compounds which are substituted 1-hydroxyalkyl-azolyl derivatives of the general formula ##STR1## in which A represents a nitrogen atom or a CH group,B represents oxygen, sulphur or a CH.sub.2 group,R represents a substituted alkyl, and, in the case in which B represents sulphur, also represents an unsubstituted alkyl, optionally substituted cyclo-alkyl or optionally substituted phenyl group,Z represents a halogen atom or an alkyl, cycloalkyl, alkoxy, alkylthio, halogenoalkyl, halogenoalkoxy, halogenoalkylthio, optionally substituted phenyl, optionally substituted phenoxy, optionally substituted phenylalkyl or optionally substituted phenylalkoxy group, andm is 0, 1, 2 or 3,and the acid addition salts and metal salt complexes thereof, are new, are prepared as described and find use as fungicides and plant growth regulators.

公开(公告)号：US4734126A

公开(公告)日：1988-03-29

申请号：US683891

申请日：1984-12-20

申请人： Graham Holmwood ,  Erik Regel ,  Gerhard Jager ,  Karl H. Buchel ,  Klaus Lurssen ,  Paul-Ernst Frohberger ,  Wilhelm Brandes ,  Volker Paul

发明人： Graham Holmwood ,  Erik Regel ,  Gerhard Jager ,  Karl H. Buchel ,  Klaus Lurssen ,  Paul-Ernst Frohberger ,  Wilhelm Brandes ,  Volker Paul

IPC分类号： A01N43/50 ,  A01N43/653 ,  C07D233/60 ,  C07D249/08 ,  C07D303/22 ,  C07D303/34 ,  C07D405/06 ,  C07D521/00 ,  A61K31/41

CPC分类号： C07D303/22 ,  A01N43/50 ,  A01N43/653 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08

摘要： Compounds which are substituted 1-hydroxyalkyl-azolyl derivatives of the general formula ##STR1## in which A represents a nitrogen atom or a CH group,B represents oxygen, sulphur or a CH.sub.2 group,R represents substituted alkyl, and, in the case in which B represents sulphur, also represents an unsubstituted alkyl, optionally substituted cycloalkyl or optionally substituted phenyl group,Z represents a halogen atom or an alkyl, cycloalkyl, alkoxy, alkylthio, halogenoalkyl, halogenoalkoxy, halogenoalkylthio, optionally substituted phenyl, optionally substituted phenoxy, optionally substituted phenylalkyl or optionally substituted phenylalkoxy group, andm is 0, 1, 2 or 3,and the acid addition salts and metal salt complexes thereof, are new, are prepared as described and find use as fungicides and plant growth regulators.

摘要翻译： 化合物，其中A表示氮原子或CH基团，B表示氧，硫或CH2基团，其中R表示取代的烷基，且表示取代的烷基， B代表硫的情况也代表未取代的烷基，任选取代的环烷基或任选取代的苯基，Z代表卤素原子或烷基，环烷基，烷氧基，烷硫基，卤代烷基，卤代烷氧基，卤代烷硫基，任选取代的苯基， 苯氧基，任选取代的苯基烷基或任选取代的苯基烷氧基，m为0,1,2或3，其酸加成盐和金属盐络合物是新的，如上所述制备，可用作杀真菌剂和植物生长调节剂。

公开(公告)号：US4632932A

公开(公告)日：1986-12-30

申请号：US549868

申请日：1983-11-08

申请人： Wolfgang Kramer ,  Karl H. Buchel ,  Graham Holmwood ,  Erik Regel ,  Manfred Plempel

发明人： Wolfgang Kramer ,  Karl H. Buchel ,  Graham Holmwood ,  Erik Regel ,  Manfred Plempel

IPC分类号： A01N43/50 ,  A01N43/653 ,  A61K31/41 ,  A61P31/04 ,  C07C45/56 ,  C07D317/26 ,  C07D319/06 ,  C07D405/06 ,  C07D405/14 ,  C07D407/04 ,  C07D407/06 ,  C07D521/00

CPC分类号： C07D231/12 ,  C07C45/56 ,  C07D233/56 ,  C07D249/08 ,  C07D317/26 ,  C07D319/06 ,  C07D407/04 ,  C07D407/06

摘要： The invention concerns the provision of compound of Formula I as defined herein as well as compositions containing compound of Formula I. Said compounds and compositions are used as antimycotic agents and the invention includes such use.

摘要翻译： 本发明涉及提供如本文所定义的式I化合物以及含有式I化合物的组合物。所述化合物和组合物用作抗真菌剂，本发明包括此类用途。