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公开(公告)号:US20070272777A1
公开(公告)日:2007-11-29
申请号:US11644567
申请日:2006-12-22
申请人: Guy Samburski , Hagit Eisen-Nevo , Judith Aronhime , Sigalit Levi
发明人: Guy Samburski , Hagit Eisen-Nevo , Judith Aronhime , Sigalit Levi
IPC分类号: B02C19/08 , C07D401/12
CPC分类号: A61K31/496 , A61K9/14
摘要: Micronized aripiprazole Form II having a particle shape and wherein 90% or more of the particles have a particle size of about 30 μm and the micronized aripiprazole Form II does not have more than 10% by weight of aripiprazole Type C as determined by X-ray diffraction and processes for making thereof.
摘要翻译: 具有颗粒形状的微粉化阿立哌唑II型,其中90%或更多的颗粒具有约30μm的粒度,并且微粉化的阿立哌唑II型不超过10倍重量的通过X射线测定的阿立哌唑C型 衍射及其制造方法。
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公开(公告)号:US20090156813A1
公开(公告)日:2009-06-18
申请号:US12315867
申请日:2008-12-04
申请人: Judith Aronhime , Ben-Zion Dolitzky , Eran Luvchick , Jean Hildesheim , Hagit Eisen-Nevo , Reuven Izsak
发明人: Judith Aronhime , Ben-Zion Dolitzky , Eran Luvchick , Jean Hildesheim , Hagit Eisen-Nevo , Reuven Izsak
IPC分类号: C07D401/12
CPC分类号: C07D215/227 , A61K31/496
摘要: The invention encompasses aripiprazole crystalline forms, methods of preparing the same, and pharmaceutical compositions having aripiprazole crystalline forms.
摘要翻译: 本发明包括阿立哌唑晶形,其制备方法和具有阿立哌唑结晶形式的药物组合物。
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公开(公告)号:US20050203299A1
公开(公告)日:2005-09-15
申请号:US11015068
申请日:2004-12-16
申请人: Judith Aronhime , Ben-Zion Dolitzky , Eran Luvchick , Jean Hildesheim , Hagit Eisen-Nevo , Reuven Izsak
发明人: Judith Aronhime , Ben-Zion Dolitzky , Eran Luvchick , Jean Hildesheim , Hagit Eisen-Nevo , Reuven Izsak
IPC分类号: A61K31/496 , C07D215/22 , C07D215/227 , C07D487/00
CPC分类号: C07D215/227 , A61K31/496
摘要: The invention encompasses aripiprazole crystalline forms, methods of preparing the same, and pharmaceutical compositions having aripiprazole crystalline forms.
摘要翻译: 本发明包括阿立哌唑晶形,其制备方法和具有阿立哌唑结晶形式的药物组合物。
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公开(公告)号:US20060241159A1
公开(公告)日:2006-10-26
申请号:US11471366
申请日:2006-06-19
申请人: Reuven Izsak , Ori Lerman , Tamas Koltai , Judith Aronhime , Michael Pinchasov , Hagit Eisen-Nevo
发明人: Reuven Izsak , Ori Lerman , Tamas Koltai , Judith Aronhime , Michael Pinchasov , Hagit Eisen-Nevo
IPC分类号: A61K31/422 , C07D413/02
CPC分类号: C07D413/06
摘要: The invention encompasses novel crystalline forms of zolmitriptan herein defined as Form B, D, C, E, F, G, H, I, J, K, M, N, O, P, Q, R, S, or Amorphous and to methods of making thereof. The invention also encompasses methods of making zolmitriptan crystalline Form A.
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公开(公告)号:US07504504B2
公开(公告)日:2009-03-17
申请号:US11015068
申请日:2004-12-16
申请人: Judith Aronhime , Ben-Zion Dolitzky , Eran Luvchick , Jean Hildesheim , Hagit Eisen-Nevo , Reuven Izsak
发明人: Judith Aronhime , Ben-Zion Dolitzky , Eran Luvchick , Jean Hildesheim , Hagit Eisen-Nevo , Reuven Izsak
IPC分类号: C07D401/12
CPC分类号: C07D215/227 , A61K31/496
摘要: The invention encompasses aripiprazole crystalline forms, methods of preparing the same, and pharmaceutical compositions having aripiprazole crystalline forms.
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公开(公告)号:US20060241160A1
公开(公告)日:2006-10-26
申请号:US11471367
申请日:2006-06-19
申请人: Reuven Izsak , Ori Lerman , Tamas Koltai , Judith Aronhime , Michael Pinchasov , Hagit Eisen-Nevo
发明人: Reuven Izsak , Ori Lerman , Tamas Koltai , Judith Aronhime , Michael Pinchasov , Hagit Eisen-Nevo
IPC分类号: A61K31/422 , C07D413/02
CPC分类号: C07D413/06
摘要: The invention encompasses novel crystalline forms of zolmitriptan herein defined as Form B, D, C, E, F, G, H, I, J, K, M, N, O, P, Q, R, S, or Amorphous and to methods of making thereof. The invention also encompasses methods of making zolmitriptan crystalline Form A.
摘要翻译: 本发明包括本文定义为形式B,D,C,E,F,G,H,I,J,K,M,N,O,P,Q,R,S或无定形的佐米曲坦的新型结晶形式, 制作方法。 本发明还包括制备唑来曲坦结晶A型的方法。
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公开(公告)号:US20060241158A1
公开(公告)日:2006-10-26
申请号:US11471364
申请日:2006-06-19
申请人: Reuven Izsak , Ori Lerman , Tamas Koltai , Judith Aronhime , Michael Pinchasov , Hagit Eisen-Nevo
发明人: Reuven Izsak , Ori Lerman , Tamas Koltai , Judith Aronhime , Michael Pinchasov , Hagit Eisen-Nevo
IPC分类号: A61K31/422 , C07D413/02
CPC分类号: C07D413/06
摘要: The invention encompasses novel crystalline forms of zolmitriptan herein defined as Form B, D, C, E, F, G, H, I, J, K, M, N, O, P, Q, R, S, or Amorphous and to methods of making thereof. The invention also encompasses methods of making zolmitriptan crystalline Form A.
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公开(公告)号:US20060211751A1
公开(公告)日:2006-09-21
申请号:US11284773
申请日:2005-11-21
申请人: Reuven Izsak , Ori Lerman , Tamas Koltai , Judith Aronhime , Michael Pinchasov , Hagit Eisen-Nevo
发明人: Reuven Izsak , Ori Lerman , Tamas Koltai , Judith Aronhime , Michael Pinchasov , Hagit Eisen-Nevo
IPC分类号: A61K31/422 , C07D413/02
CPC分类号: C07D413/06
摘要: The invention encompasses novel crystalline forms of zolmitriptan herein defined as Form B, D, C, E, F, G, H, I, J, K, M, N, O, P, Q, R, S, or Amorphous and to methods of making thereof. The invention also encompasses methods of making zolmitriptan crystalline Form A.
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公开(公告)号:US20080125476A1
公开(公告)日:2008-05-29
申请号:US11824536
申请日:2007-06-28
申请人: Santiago Ini , Sigalit Levi , Michal Rafilovich , Judith Aronhime , Mili Abramov , Ron Bar-Shavit , Eran Turgeman
发明人: Santiago Ini , Sigalit Levi , Michal Rafilovich , Judith Aronhime , Mili Abramov , Ron Bar-Shavit , Eran Turgeman
IPC分类号: A61K31/403 , C07D209/82
CPC分类号: C07D209/88
摘要: The invention encompasses novel amorphous and crystalline forms of carvedilol phosphate, carvedilol hydrogen phosphate, and carvedilol dihydrogen phosphate as well as methods of making the novel amorphous and crystalline forms. Also disclosed are pharmaceutical compositions comprising the novel amorphous and crystalline forms and uses thereof.
摘要翻译: 本发明包括磷酸卡维地洛,卡维地洛磷酸氢盐和卡维地洛二磷酸盐的新型无定形和结晶形式以及制备新型无定形和结晶形式的方法。 还公开了包含新型无定形和结晶形式及其用途的药物组合物。
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公开(公告)号:US20070293702A1
公开(公告)日:2007-12-20
申请号:US11709906
申请日:2007-02-21
IPC分类号: C07C233/05
CPC分类号: C07C317/44
摘要: The invention encompasses crystalline forms of armodafinil, processes for preparing the crystalline forms, and pharmaceutical formulation
摘要翻译: 本发明包括结构形式的臂多巴尼,制备结晶形式的方法和药物制剂
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