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公开(公告)号:US5147871A
公开(公告)日:1992-09-15
申请号:US803757
申请日:1991-12-05
IPC分类号: A61K47/48 , C07D501/34
CPC分类号: B82Y5/00 , A61K47/48115 , A61K47/4813 , A61K47/48761
摘要: There are presented anti-bacterial cephalosporins having broad antimicrobial activity of the formula ##STR1## wherein R.sub.1 is an antibiotically active quinolonyl; R.sub.2 is selected from the group consisting of hydrogen, lower alkoxy, amino, lower alkylthio and amido; R.sub.3 is selected from the group consisting of hydrogen, and acyl group, and m is 0, 1 or 2 and the readily hydrolysable esters or salts of these compounds and hydrates of the compounds of formula I or of their esters or salts.
摘要翻译: 提出了具有广泛的抗菌活性的抗菌头孢菌素,其具有下式其中R 1是抗生物活性喹啉酮; R2选自氢,低级烷氧基,氨基,低级烷硫基和酰氨基; R3选自氢和酰基,m为0,1或2,这些化合物的易水解的酯或盐和式I化合物的水合物或其酯或盐。