METHOD FOR ACTIVATING HELPER T CELL
    2.
    发明申请
    METHOD FOR ACTIVATING HELPER T CELL 审中-公开
    激活HELPER T细胞的方法

    公开(公告)号:US20130266958A1

    公开(公告)日:2013-10-10

    申请号:US13877768

    申请日:2011-10-04

    IPC分类号: C07K7/08

    摘要: The present invention relates to a method for activating helper T cells, which includes the step of activating helper T cells by adding a WT1 peptide to antigen presenting cells, wherein the WT1 peptide has the ability to bind to any MHC class II molecule of an HLA-DRB1* 0101 molecule, an HLA-DRB1* 0401 molecule, an HLA-DRB1* 0403 molecule, an HLA-DRB1* 0406 molecule, an HLA-DRB1* 0803 molecule, an HLA-DRB1* 0901 molecule, an HLA-DRB1* 1101 molecule, an HLA-DRB3* 0202 molecule, an HLA-DRB4* 0101 molecule, an HLA-DPB1* 0201 molecule or an HLA-DPB1* 0301 molecule, and the like.

    摘要翻译: 本发明涉及一种用于激活辅助性T细胞的方法,其包括通过向抗原呈递细胞添加WT1肽来激活辅助T细胞的步骤,其中WT1肽具有结合HLA的任何MHC II类分子的能力 -DRB1 * 0101分子,HLA-DRB1 * 0401分子,HLA-DRB1 * 0403分子,HLA-DRB1 * 0406分子,HLA-DRB1 * 0803分子,HLA-DRB1 * 0901分子,HLA-DRB1 HLA-DRB3 * 0202分子,HLA-DRB4 * 0101分子,HLA-DPB1 * 0201分子或HLA-DPB1 * 0301分子等。