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公开(公告)号：US08092710B2
公开(公告)日：2012-01-10
申请号：US11275200
申请日：2005-12-19
申请人： Sanat Mohanty , Hassan Sahouani , Cristin E. Moran
发明人： Sanat Mohanty , Hassan Sahouani , Cristin E. Moran
CPC分类号： C09K19/52 , A61K47/6905 , A61K49/0043 , A61K49/0056 , C09K19/3475 , C09K19/348 , C09K19/40 , Y10T428/10 , Y10T428/1059 , Y10T428/25
摘要： A method of making a chromonic structure comprises (a) preparing a first aqueous mixture comprising (i) a continuous water-soluble polymer phase and (ii) a discontinuous chromonic phase comprising a chromonic material, to form chromonic nanoparticles; (b) non-covalently crosslinking the resulting chromonic nanoparticles with a multivalent cation salt; (c) dispersing the resulting crosslinked chromonic nanoparticles in a water-soluble polymer phase to form a chromonic nanoparticle dispersion; and (d) preparing a second aqueous mixture comprising (i) the chromonic nanoparticle dispersion and (ii) a continuous chromonic phase comprising a chromonic material.
摘要翻译： 制备发色结构的方法包括（a）制备第一含水混合物，其包含（i）连续的水溶性聚合物相和（ii）包含发色材料的不连续发色相，以形成发色纳米颗粒; （b）用多价阳离子盐非共价交联得到的发色纳米颗粒; （c）将所得交联的发色纳米颗粒分散在水溶性聚合物相中以形成发色纳米颗粒分散体; 和（d）制备第二含水混合物，其包含（i）发色纳米颗粒分散体和（ii）包含发色材料的连续发色相。
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公开(公告)号：US07718716B2
公开(公告)日：2010-05-18
申请号：US11250675
申请日：2005-10-14
CPC分类号： A61Q19/00 , A61K8/02 , A61K2800/413 , B82Y5/00
摘要： A chromonic nanoparticle mixture prepared by combining (i) a continuous water-soluble polymer phase and (ii) a discontinuous chromonic phase comprising a chromonic material; and non-covalently crosslinking the resulting chromonic nanoparticles with a polyvalent cation salt.
摘要翻译： 通过组合（i）连续水溶性聚合物相和（ii）包含发色材料的不连续发色相制备的发色纳米颗粒混合物; 并用多价阳离子盐非共价交联得到的发色纳米颗粒。
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公开(公告)号：US20090324955A1
公开(公告)日：2009-12-31
申请号：US12554441
申请日：2009-09-04
申请人： Sanat Mohanty , Hassan Sahouani , Cristin E. Moran
发明人： Sanat Mohanty , Hassan Sahouani , Cristin E. Moran
IPC分类号： B32B9/00
CPC分类号： A61K9/0019 , A61K47/22 , Y10T428/2989 , Y10T428/2991 , Y10T428/31504
摘要： A method of making a multilayered chromonic structure comprises (a) preparing a first aqueous mixture comprising (i) a first continuous water-soluble polymer phase and (ii) a first discontinuous chromonic phase comprising a chromonic material, to form chromonic nanoparticles; (b) non-covalently crosslinking the resulting chromonic nanoparticles with a multivalent cation salt; (c) dispersing the resulting crosslinked chromonic nanoparticles in a composition comprising a chromonic material to form a chromonic nanoparticle dispersion; and (d) preparing a second aqueous mixture comprising (i) a second discontinuous chromonic phase comprising the chromonic nanoparticle dispersion and (ii) a second continuous water-soluble polymer phase, to encapsulate the chromonic nanoparticles; wherein at least one of the first discontinuous chromonic phase and the second discontinuous chromonic phase further comprises a guest compound.
摘要翻译： 制备多层发色结构的方法包括（a）制备第一含水混合物，其包含（i）第一连续水溶性聚合物相和（ii）包含发色材料的第一不连续发色相，以形成发色纳米颗粒; （b）用多价阳离子盐非共价交联得到的发色纳米颗粒; （c）将得到的交联发色纳米颗粒分散在包含发色材料的组合物中以形成发色纳米粒子分散体; 和（d）制备第二含水混合物，其包含（i）包含发色纳米颗粒分散体的第二不连续发色相和（ii）第二连续水溶性聚合物相，以包封发色纳米颗粒; 其中所述第一不连续发色相和所述第二不连续发色相中的至少一个还包含客体化合物。
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公开(公告)号：US07601769B2
公开(公告)日：2009-10-13
申请号：US11275202
申请日：2005-12-19
申请人： Sanat Mohanty , Hassan Sahouani , Cristin E. Moran
发明人： Sanat Mohanty , Hassan Sahouani , Cristin E. Moran
CPC分类号： A61K9/0019 , A61K47/22 , Y10T428/2989 , Y10T428/2991 , Y10T428/31504
摘要： A method of making a multilayered chromonic structure comprises (a) preparing a first aqueous mixture comprising (i) a first continuous water-soluble polymer phase and (ii) a first discontinuous chromonic phase comprising a chromonic material, to form chromonic nanoparticles;(b) non-covalently crosslinking the resulting chromonic nanoparticles with a multivalent cation salt; (c) dispersing the resulting crosslinked chromonic nanoparticles in a composition comprising a chromonic material to form a chromonic nanoparticle dispersion; and (d) preparing a second aqueous mixture comprising (i) a second discontinuous chromonic phase comprising the chromonic nanoparticle dispersion and (ii) a second continuous water-soluble polymer phase, to encapsulate the chromonic nanoparticles; wherein at least one of the first discontinuous chromonic phase and the second discontinuous chromonic phase further comprises a guest compound.
摘要翻译： 制备多层发色结构的方法包括（a）制备第一含水混合物，其包含（i）第一连续水溶性聚合物相和（ii）包含发色材料的第一不连续发色相以形成发色纳米颗粒;（b ）用多价阳离子盐非共价交联得到的发色纳米颗粒; （c）将得到的交联发色纳米颗粒分散在包含发色材料的组合物中以形成发色纳米粒子分散体; 和（d）制备第二含水混合物，其包含（i）包含发色纳米颗粒分散体的第二不连续发色相和（ii）第二连续水溶性聚合物相，以包封发色纳米颗粒; 其中所述第一不连续发色相和所述第二不连续发色相中的至少一个还包含客体化合物。
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公开(公告)号：US07993748B2
公开(公告)日：2011-08-09
申请号：US12554441
申请日：2009-09-04
申请人： Sanat Mohanty , Hassan Sahouani , Cristin E. Moran
发明人： Sanat Mohanty , Hassan Sahouani , Cristin E. Moran
CPC分类号： A61K9/0019 , A61K47/22 , Y10T428/2989 , Y10T428/2991 , Y10T428/31504
摘要： A method of making a multilayered chromonic structure comprises (a) preparing a first aqueous mixture comprising (i) a first continuous water-soluble polymer phase and (ii) a first discontinuous chromonic phase comprising a chromonic material, to form chromonic nanoparticles; (b) non-covalently crosslinking the resulting chromonic nanoparticles with a multivalent cation salt; (c) dispersing the resulting crosslinked chromonic nanoparticles in a composition comprising a chromonic material to form a chromonic nanoparticle dispersion; and (d) preparing a second aqueous mixture comprising (i) a second discontinuous chromonic phase comprising the chromonic nanoparticle dispersion and (ii) a second continuous water-soluble polymer phase, to encapsulate the chromonic nanoparticles; wherein at least one of the first discontinuous chromonic phase and the second discontinuous chromonic phase further comprises a guest compound.
摘要翻译： 制备多层发色结构的方法包括（a）制备第一含水混合物，其包含（i）第一连续水溶性聚合物相和（ii）包含发色材料的第一不连续发色相，以形成发色纳米颗粒; （b）用多价阳离子盐非共价交联得到的发色纳米颗粒; （c）将得到的交联发色纳米颗粒分散在包含发色材料的组合物中以形成发色纳米粒子分散体; 和（d）制备第二含水混合物，其包含（i）包含发色纳米颗粒分散体的第二不连续发色相和（ii）第二连续水溶性聚合物相，以包封发色纳米颗粒; 其中所述第一不连续发色相和所述第二不连续发色相中的至少一个还包含客体化合物。
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公开(公告)号：US20110020540A1
公开(公告)日：2011-01-27
申请号：US12895013
申请日：2010-09-30
申请人： Hassan Sahouani , Sanat Mohanty , Cristin E. Moran
发明人： Hassan Sahouani , Sanat Mohanty , Cristin E. Moran
IPC分类号： B05D7/00
CPC分类号： B01J13/02 , Y10T428/2984
摘要： A method of making encapsulated chromonic nanoparticles includes exposing crosslinked chromonic nanoparticles to an acid selected from the group consisting of carbonic acid, phosphoric acid, lactic acid, citric acid, boric acid, sulfuric acid, and mixtures thereof in the presence of water to encapsulate the crosslinked nanoparticles in a shell comprising a complex comprising the chromonic material, the multivalent cations, and the acid anions.
摘要翻译： 制备包封的发色纳米颗粒的方法包括在水存在下将交联的发色纳米颗粒暴露于选自碳酸，磷酸，乳酸，柠檬酸，硼酸，硫酸及其混合物中的酸，以将 包含包含发色材料，多价阳离子和酸性阴离子的络合物的壳中的交联纳米颗粒。
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公开(公告)号：US07824732B2
公开(公告)日：2010-11-02
申请号：US11275364
申请日：2005-12-28
申请人： Hassan Sahouani , Sanat Mohanty , Cristin E. Moran
发明人： Hassan Sahouani , Sanat Mohanty , Cristin E. Moran
IPC分类号： A61K35/12
CPC分类号： B01J13/02 , Y10T428/2984
摘要： A method of making encapsulated chromonic nanoparticles includes exposing crosslinked chromonic nanoparticles to an acid selected from the group consisting of carbonic acid, phosphoric acid, lactic acid, citric acid, boric acid, sulfuric acid, and mixtures thereof in the presence of water to encapsulate the crosslinked nanoparticles in a shell comprising a complex comprising the chromonic material, the multivalent cations, and the acid anions.
摘要翻译： 制备包封的发色纳米颗粒的方法包括在水存在下将交联的发色纳米颗粒暴露于选自碳酸，磷酸，乳酸，柠檬酸，硼酸，硫酸及其混合物中的酸，以将 包含包含发色材料，多价阳离子和酸性阴离子的络合物的壳中的交联纳米颗粒。
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公开(公告)号：US20120077022A1
公开(公告)日：2012-03-29
申请号：US13310292
申请日：2011-12-02
申请人： Sanat Mohanty , Hassan Sahouani , Cristin E. Moran
发明人： Sanat Mohanty , Hassan Sahouani , Cristin E. Moran
CPC分类号： C09K19/52 , A61K47/6905 , A61K49/0043 , A61K49/0056 , C09K19/3475 , C09K19/348 , C09K19/40 , Y10T428/10 , Y10T428/1059 , Y10T428/25
摘要： A method of making a chromonic structure comprises (a) preparing a first aqueous mixture comprising (i) a continuous water-soluble polymer phase and (ii) a discontinuous chromonic phase comprising a chromonic material, to form chromonic nanoparticles; (b) non-covalently crosslinking the resulting chromonic nanoparticles with a multivalent cation salt; (c) dispersing the resulting crosslinked chromonic nanoparticles in a water-soluble polymer phase to form a chromonic nanoparticle dispersion; and (d) preparing a second aqueous mixture comprising (i) the chromonic nanoparticle dispersion and (ii) a continuous chromonic phase comprising a chromonic material.
摘要翻译： 制备发色结构的方法包括（a）制备第一含水混合物，其包含（i）连续的水溶性聚合物相和（ii）包含发色材料的不连续发色相，以形成发色纳米颗粒; （b）用多价阳离子盐非共价交联得到的发色纳米颗粒; （c）将所得交联的发色纳米颗粒分散在水溶性聚合物相中以形成发色纳米颗粒分散体; 和（d）制备第二含水混合物，其包含（i）发色纳米颗粒分散体和（ii）包含发色材料的连续发色相。
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公开(公告)号：US07981469B2
公开(公告)日：2011-07-19
申请号：US12895013
申请日：2010-09-30
申请人： Hassan Sahouani , Sanat Mohanty , Cristin E. Moran
发明人： Hassan Sahouani , Sanat Mohanty , Cristin E. Moran
IPC分类号： B01J13/02
CPC分类号： B01J13/02 , Y10T428/2984
摘要： A method of making encapsulated chromonic nanoparticles includes exposing crosslinked chromonic nanoparticles to an acid selected from the group consisting of carbonic acid, phosphoric acid, lactic acid, citric acid, boric acid, sulfuric acid, and mixtures thereof in the presence of water to encapsulate the crosslinked nanoparticles in a shell comprising a complex comprising the chromonic material, the multivalent cations, and the acid anions.
摘要翻译： 制备包封的发色纳米颗粒的方法包括在水存在下将交联的发色纳米颗粒暴露于选自碳酸，磷酸，乳酸，柠檬酸，硼酸，硫酸及其混合物中的酸，以将 包含包含发色材料，多价阳离子和酸性阴离子的络合物的壳中的交联纳米颗粒。
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公开(公告)号：US07629027B2
公开(公告)日：2009-12-08
申请号：US11250290
申请日：2005-10-14
IPC分类号： B05D5/00
CPC分类号： A61K8/02 , A61K9/145 , A61K9/5115 , A61K9/5192 , A61K2800/413 , A61Q19/00 , B82Y5/00 , C09K19/02 , Y10T428/10 , Y10T428/1005 , Y10T428/1041
摘要： A chromonic nanoparticle mixture prepared by combining (i) a continuous water-soluble polymer phase and (ii) a discontinuous chromonic phase comprising a chromonic material; and non-covalently crosslinking the resulting chromonic nanoparticles with a polyvalent cation salt.
摘要翻译： 通过组合（i）连续水溶性聚合物相和（ii）包含发色材料的不连续发色相制备的发色纳米颗粒混合物; 并用多价阳离子盐非共价交联得到的发色纳米颗粒。
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