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    Anticholinergics, processes for preparing them and pharmaceutical composition containing them
    3.
    发明授权
    Anticholinergics, processes for preparing them and pharmaceutical composition containing them 有权
    抗胆碱能药，其制备方法和含有它们的药物组合物

    公开(公告)号：US07652138B2

    公开(公告)日：2010-01-26

    申请号：US10970240

    申请日：2004-10-21

    申请人： Helmut Meissner ,  Gerd Morschhaeuser ,  Michael Paul Pieper ,  Gerald Pohl ,  Richard Reichl ,  Georg Speck

    发明人： Helmut Meissner ,  Gerd Morschhaeuser ,  Michael Paul Pieper ,  Gerald Pohl ,  Richard Reichl ,  Georg Speck

    IPC分类号： C07D491/00 ,  C07D451/00

    CPC分类号： C07D451/10 ,  C07D451/14

    摘要： A compound of formula 1 wherein: A is a group selected from X− is an anion with a single negative charge; R1 and R2 are each independently a C1-C4-alkyl optionally substituted with hydroxy or halogen; and R3, R4, R5, R6, R7, and R8 are each independently hydrogen, C1-C4-alkyl, C1-C4-alkyloxy, hydroxy, CF3, CN, NO2, or halogen, with the proviso that at least one of the groups R3, R4, R5, R6, R7, and R8 is not hydrogen, processes for preparing these compounds, pharmaceutical compositions containing these compounds, and their use as pharmaceutical compositions.

    摘要翻译： 式1的化合物，其中：A是选自X - 是具有单个负电荷的阴离子; R 1和R 2各自独立地为任选被羟基或卤素取代的C 1 -C 4烷基; 并且R 3，R 4，R 5，R 6，R 7和R 8各自独立地为氢，C 1 -C 4 - 烷基，C 1 -C 4 - 烷氧基，羟基，CF 3，CN，NO 2或卤素，条件是至少一个 R 3，R 4，R 5，R 6，R 7和R 8不是氢，制备这些化合物的方法，含有这些化合物的药物组合物及其作为药物组合物的用途。