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公开(公告)号:US20050175551A1
公开(公告)日:2005-08-11
申请号:US10516874
申请日:2003-10-24
申请人: Heng Cai , Marian Holerca , Arthur Chen , Van Canady , John Afflitto
发明人: Heng Cai , Marian Holerca , Arthur Chen , Van Canady , John Afflitto
CPC分类号: D01F6/90 , A46D1/00 , A46D1/0207 , A61C15/041 , A61K8/88 , A61K8/898 , A61Q11/00 , C08G69/42 , C08G77/455 , C08L83/10 , D01F1/103 , C08L2666/14
摘要: The invention is directed to a new material useful in oral care products such as dental floss or as a toothbrush bristle. The material is a silicon-modified polyamide blended with a different polyamide material. The preferred different polyamide material is the conventional material used to make bristles of toothbrushes. The different polyamide material is preferably a nylon material.
摘要翻译: 本发明涉及用于口腔护理产品如牙线或牙刷刷毛的新材料。 该材料是与不同的聚酰胺材料共混的硅改性聚酰胺。 优选的不同的聚酰胺材料是用于制造牙刷刷毛的常规材料。 不同的聚酰胺材料优选为尼龙材料。
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公开(公告)号:US07011822B2
公开(公告)日:2006-03-14
申请号:US10349857
申请日:2003-01-23
申请人: Eric Guenin , Jairajh Mattai , John Afflitto , John Hogan , John Jonas , Wilson Lee , Elizabeth Linn , Rosemary Munsayac , Xiaozhong Tang , Kathy Potechin
发明人: Eric Guenin , Jairajh Mattai , John Afflitto , John Hogan , John Jonas , Wilson Lee , Elizabeth Linn , Rosemary Munsayac , Xiaozhong Tang , Kathy Potechin
CPC分类号: A61Q15/00 , A61K8/0241 , A61K8/8111 , A61K8/891 , A61K8/892 , A61K2800/31 , A61K2800/412 , A61K2800/614 , A61K2800/654
摘要: A low residue antiperspirant and/or deodorant composition in the form of an anhydrous, surfactant-free and antiseptic alcohol-free suspension exhibiting a syneresis of less than 8% which is made by combining selected amounts of: (a) a cyclomethicone (and) dimethicone crosspolymer made with an ≡Si—H containing polysiloxane and an alpha, omega-diene of formula CH2═CH(CH2)xCH═CH2 which crosspolymer has a viscosity in the range of 50,000–3,000,000 centipoise, preferably with a nonvolatiles content of 10–14% in cyclomethicone; (b) polyethylene beads having a density in the range of 0.91–0.98 grams/cm3 and a particle size in the range of 5–40 microns; (c) a volatile silicone; (d) an emollient (or a mixture of two or more emollients) which may include a non-volatile silicone and an additional amount of a volatile silicone; and (e) an effective amount of an antiperspirant active material in an amount sufficient to have an antiperspirant and/or a deodorant effect.
摘要翻译: 形式为无水,无表面活性剂和防腐的无醇悬浮液形式的低残留止汗剂和/或除臭剂组合物,其表现出小于8%的脱水收缩率,其通过将选定量的组合(a)环甲基硅氧烷(和) 由含≡Si-H的聚硅氧烷和式CH 2 -CH(CH 2 CH 2)x的α,ω-二烯制备的聚二甲基硅氧烷交联聚合物 CH-CH 2 2该交联聚合物的粘度在50,000-3,000,000厘泊的范围内,优选在环甲基硅酮中的非挥发物含量为10-14%; (b)密度在0.91-0.98克/平方厘米的范围内的聚乙烯珠粒和5-40微米范围内的粒度; (c)挥发性硅酮; (d)润肤剂(或两种或多种润肤剂的混合物),其可以包括非挥发性硅氧烷和额外量的挥发性硅氧烷; 和(e)有效量的足够具有止汗剂和/或除臭效果的止汗活性物质。
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公开(公告)号:US6110446A
公开(公告)日:2000-08-29
申请号:US166025
申请日:1998-10-05
申请人: Michael Prencipe , Vincent O. Drago , Mike Wong , Barry D. Self , Malcolm Williams , John Afflitto
发明人: Michael Prencipe , Vincent O. Drago , Mike Wong , Barry D. Self , Malcolm Williams , John Afflitto
CPC分类号: A61Q11/00 , A61K8/22 , A61K8/24 , A61K8/73 , A61K8/8147 , A61K2800/88
摘要: A dual component antiplaque and whitening dentifrice composition in which the first component is a paste composition containing an antibacterial agent such as Triclosan and the second component contains a peroxide compound such as hydrogen peroxide in a vehicle thickened with a combination of an inorganic thickeners and an organic thickener other than an alkylene oxide polymer wherein the antiplaque and whitening efficacy of the components is unimpaired when the components are physically separated prior to use and thereafter are mixed upon application to dental tissue.
摘要翻译: 双组分抗菌和增白牙粉组合物,其中第一组分是含有抗菌剂如三氯生的糊组合物,第二组分在无机增稠剂和有机物的组合物中加入过氧化氢等过氧化物化合物 除了环氧烷聚合物之外的增稠剂,其中当组分在使用之前物理分离时,组分的抗牙斑和增白功效不受损害,然后在施用于牙齿组织时混合。
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公开(公告)号:US5292526A
公开(公告)日:1994-03-08
申请号:US966104
申请日:1992-10-23
申请人: Abdul Gaffar , Nuran Nabi , John Afflitto , Orum Stringer
发明人: Abdul Gaffar , Nuran Nabi , John Afflitto , Orum Stringer
CPC分类号: A61Q11/00 , A61K8/24 , A61K8/347 , A61K8/42 , A61K8/8164 , Y10S526/936
摘要: An oral composition such as a dentifrice, mouthwash, lozenge or chewing gum containing a polyphosphate anticalculus agent, such as tetraalkali metal pyrophosphate and antibacterial antiplaque agent compatible therewith. The antiplaque agent is a substantially water-insoluble noncationic antibacterial agent such as 2,4,4'-trichloro-2'-hydroxydiphenyl ether (Triclosan). Antiplaque effectiveness is optimized by the presence of an antibacterial-enhancing agent which enhances delivery of said antibacterial agent to, and retention thereof on, oral surfaces.
摘要翻译: 口服组合物如洁牙剂,漱口剂,锭剂或口香糖,其含有多磷酸抗结石剂,例如四碱金属焦磷酸盐和与其相容的抗菌抗菌剂。 抗牙斑剂是基本上不溶于水的非阳离子抗菌剂,例如2,4,4'-三氯-2'-羟基二苯醚(三氯生)。 通过抗增生剂的存在来优化抗斑效果,其增强了所述抗菌剂在口腔表面上的输送和保留。
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公开(公告)号:US5275805A
公开(公告)日:1994-01-04
申请号:US075255
申请日:1993-06-11
申请人: Nuran Nabi , Abdul Gaffar , John Afflitto
发明人: Nuran Nabi , Abdul Gaffar , John Afflitto
IPC分类号: A61K8/00 , A61K20060101 , A61K8/42 , A61K8/46 , A61K8/86 , A61K8/90 , A61K31/80 , A61P1/02 , A61Q11/00 , A61K7/16 , A61K7/22
摘要: An antiplaque oral composition such as a gel, paste or mouthrinse which is comprised of a vehicle having incorporated therein as the antiplaque agent an effective amount of an antibacterial salicylanilide compound and a surfactant mixture of an anionic surfactant, a polyoxyethylene/polyoxypropylene block copolymer and a taurate salt, the pH of the composition being adjusted to a pH of at least 8.0. An antibacterial-enhancing agent such as an anionic polymeric polycarboxylate which enhances the delivery of the salicylanilide compound to and retention on oral tissue surfaces is optionally incorporated in the composition to improve the efficacy of the salicylanilide compound.
摘要翻译: 一种防斑口服组合物,例如凝胶,糊剂或漱口水,其由其中掺入抗牙斑剂的载体组成,有效量的抗菌水杨酰苯胺化合物和阴离子表面活性剂,聚氧乙烯/聚氧丙烯嵌段共聚物和 牛磺酸盐,将组合物的pH调节至至少8.0的pH。 任选地在组合物中引入增强将水杨酰苯胺化合物递送到口腔组织表面上并保留在口腔组织表面上的抗菌增强剂如阴离子聚合多羧酸盐,以提高水杨酰苯胺化合物的功效。
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公开(公告)号:US5192530A
公开(公告)日:1993-03-09
申请号:US754887
申请日:1991-09-06
申请人: Abdul Gaffar , Nuran Nabi , John Afflitto , Orum Stringer
发明人: Abdul Gaffar , Nuran Nabi , John Afflitto , Orum Stringer
摘要: An oral composition dentifrice comprising an orally acceptable vehicle, about 5-30% by weight of a siliceous polishing agent, a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2'-hydroxydiphenyl ether (triclosan), and an antibacterial-enhancing agent which enhances the delivery of said antibacterial agent to, and retention thereof on, oral surfaces, wherein said antiplaque agent is substantially completely dissolved in saliva present during tooth and gum cleaning in a solubilizing agent therefor. The solubilizing agent may be a humectant polyol such as propylene glycol, dipropylene glycol and hexylene glycol; a cellosolve such as methyl cellosolve and ethyl cellosolve; a vegetable oil or wax containing at least about 12 carbon atoms in a straight chain such as olive oil, castor oil and petrolatum; or an ester such as ethyl acetate, amyl acetate, glyceryl tristearate and benzyl benzoate.
摘要翻译: 一种口服组合物洁齿剂,其包含口服可接受的载体,约5-30重量%的硅质抛光剂,基本上不溶于水的非阳离子抗菌抗斑剂如2,4,4'-三氯-2'-羟基二苯醚( 三氯生)和增强所述抗菌剂输送到其口腔表面上的抗菌增强剂,其中所述抗牙斑剂在牙齿和牙龈清洁过程中基本上完全溶解在存在的唾液中,用于增溶剂。 增溶剂可以是保湿多元醇,例如丙二醇,二丙二醇和己二醇; 溶纤剂如甲基溶纤剂和乙基溶纤剂; 在直链如橄榄油,蓖麻油和凡士林中含有至少约12个碳原子的植物油或蜡; 或酯如乙酸乙酯,乙酸戊酯,三硬脂酸甘油酯和苯甲酸苄酯。
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7.
公开(公告)号:US5976508A
公开(公告)日:1999-11-02
申请号:US943821
申请日:1997-10-06
申请人: Nuran Nabi , John Afflitto , Malcolm Williams , Susan Herles , Prem Sreenivasan
发明人: Nuran Nabi , John Afflitto , Malcolm Williams , Susan Herles , Prem Sreenivasan
CPC分类号: A61K8/22 , A61K8/19 , A61K8/347 , A61K8/365 , A61Q11/00 , A61K2800/58 , A61K2800/88
摘要: A method for enhancing the antiplaque efficacy of an antibacterial dentifrice, comprising preparing a multicomponent dentifrice composition having a first dentifrice component containing an antibacterial agent and manganese coordination complex compound, and a second dentifrice component containing a peroxide compound; maintaining the first and second dentifrice components separately prior to use; combining the dentifrice components and applying the two components to the teeth and periodontium, whereby the dentifrice provides enhanced inhibition of plaque growth.
摘要翻译: 一种增强抗菌洁牙剂的抗牙斑功效的方法,包括制备具有含有抗菌剂和锰配位络合物的第一洁齿剂组分的多组分洁齿剂组合物和含有过氧化物的第二洁齿剂组分; 在使用前分别保持第一和第二洁牙剂组分; 将洁齿剂组分和将两种组分施用于牙齿和牙周组合,由此洁齿剂提供增强的斑块生长抑制。
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公开(公告)号:US5728756A
公开(公告)日:1998-03-17
申请号:US668754
申请日:1996-06-24
申请人: Abdul Gaffar , Nuran Nabi , John Afflitto , Orum Stringer
发明人: Abdul Gaffar , Nuran Nabi , John Afflitto , Orum Stringer
CPC分类号: C08F230/02 , A61K8/24 , A61K8/347 , A61K8/42 , A61K8/81 , A61K8/8164 , A61Q11/00 , A61K2800/87
摘要: An oral composition dentifrice comprising an orally acceptable vehicle, about 5-30% by weight of a siliceous polishing agent, a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2'-hydroxydiphenyl ether (triclosan), and an antibacterial-enhancing agent which enhances the delivery of said antibacterial agent to, and retention thereof on, oral surfaces, wherein said antiplaque agent is substantially completely dissolved in saliva present during tooth and gum cleaning in a solubilizing agent therefor. The solubilizing agent may be a humectant polyol such as propylene glycol, dipropylene glycol and hexylene glycol; a cellosolve such as methy cellosolve and ethyl cellosolve: a vegetable oil or wax containing at least about 12 carbon atoms in a straight chain such as olive oil, castor oil and petrolatum; or an ester such as ethyl acetate, amyl acetate, glyceryl tristearate and benzyl benzoate.
摘要翻译: 一种口服组合物洁齿剂,其包含口服可接受的载体,约5-30重量%的硅质抛光剂,基本上不溶于水的非阳离子抗菌抗斑剂如2,4,4'-三氯-2'-羟基二苯醚( 三氯生)和增强所述抗菌剂输送到其口腔表面上的抗菌增强剂,其中所述抗牙斑剂在牙齿和牙龈清洁过程中基本上完全溶解在存在的唾液中,用于增溶剂。 增溶剂可以是保湿多元醇,例如丙二醇,二丙二醇和己二醇; 溶纤剂如甲基溶纤剂和乙基溶纤剂:在直链如橄榄油,蓖麻油和凡士林中含有至少约12个碳原子的植物油或蜡; 或酯如乙酸乙酯,乙酸戊酯,三硬脂酸甘油酯和苯甲酸苄酯。
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公开(公告)号:US5686064A
公开(公告)日:1997-11-11
申请号:US187984
申请日:1994-01-28
申请人: Abdul Gaffar , Nuran Nabi , John Afflitto , Orum Stringer
发明人: Abdul Gaffar , Nuran Nabi , John Afflitto , Orum Stringer
CPC分类号: A61Q11/00 , A61K8/24 , A61K8/347 , A61K8/42 , A61K8/8164 , Y10S526/936
摘要: An oral composition such as a dentifrice, mouthwash, lozenge or chewing gum containing a polyphosphate anticalculus agent, such as tetraalkali metal pyrophosphate and antibacterial antiplaque agent compatible therewith. The antiplaque agent is a substantially water-insoluble noncationic antibacterial agent such as 2,4,4'-trichloro-2'-hydroxydiphenyl ether (Triclosan). Antiplaque effectiveness is optimized by the presence of an antibacterial-enhancing agent which enhances delivery of said antibacterial agent to, and retention thereof on, oral surfaces.
摘要翻译: 口服组合物如洁牙剂,漱口剂,锭剂或口香糖,其含有多磷酸抗结石剂,例如四碱金属焦磷酸盐和与其相容的抗菌抗菌剂。 抗牙斑剂是基本上不溶于水的非阳离子抗菌剂,例如2,4,4'-三氯-2'-羟基二苯醚(三氯生)。 通过抗增生剂的存在来优化抗斑效果,其增强了所述抗菌剂在口腔表面上的输送和保留。
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公开(公告)号:US5180578A
公开(公告)日:1993-01-19
申请号:US657885
申请日:1991-02-19
申请人: Abdul Gaffar , Nuran Nabi , John Afflitto , Orum Stringer
发明人: Abdul Gaffar , Nuran Nabi , John Afflitto , Orum Stringer
CPC分类号: A61Q11/00 , A61K8/24 , A61K8/347 , A61K8/42 , A61K8/8164 , Y10S526/936
摘要: An oral composition such as a dentifrice, mouthwash, lozenge or chewing gum containing a polyphosphate anticalculus agent, such as tetraalkali metal pyrophosphate and antibacterial antiplaque agent compatible therewith. The antiplaque agent is a substantially water-insoluble noncationic antibacterial agent such as 2,4,4'-trichloro-2'-hydroxydiphenyl ether (Triclosan). Antiplaque effectiveness is optimized by the presence of an antibacterial-enhancing agent which enhances delivery of said antibacterial agent to, and retention thereof on, oral surfaces.
摘要翻译: 口服组合物如洁牙剂,漱口剂,锭剂或口香糖,其含有多磷酸抗结石剂,例如四碱金属焦磷酸盐和与其相容的抗菌抗菌剂。 抗牙斑剂是基本上不溶于水的非阳离子抗菌剂,例如2,4,4'-三氯-2'-羟基二苯醚(三氯生)。 通过抗增生剂的存在来优化抗斑效果,其增强了所述抗菌剂在口腔表面上的输送和保留。
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