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公开(公告)号：US20100313886A1
公开(公告)日：2010-12-16
申请号：US12671115
申请日：2008-07-31
IPC分类号： A61M15/00
CPC分类号： A61M15/0028 , A61M15/003 , A61M15/0033 , A61M2202/064 , A61M2206/16
摘要： In an inhaler for administering a powdery medicament in the form of an inhalable substance, substance formulation or mixture, a blister cavity to be opened by piercing elements (11) is mounted in the lower part (1) of a housing (2), which is composed of an upper part (6), designed as mouthpiece and with an inhalation channel (16), and of the lower part (1), which comprises an air inlet opening (9). The inhalation channel (16) of the upper part (6) of the housing has a unit (15) for dispersing the powdery medicament, said unit (15) being connected to the piercing elements (11), wherein the upper part (6) of the housing can be moved relative to the lower part (1) of the housing in order to open the blister cavity.
摘要翻译： 在用于施用可吸入物质，物质制剂或混合物形式的粉末药物的吸入器中，通过刺穿元件（11）打开的泡罩腔被安装在壳体（2）的下部（1）中， 由设置为接口并具有吸入通道（16）的上部（6）和包括进气口（9）的下部（1）组成。 壳体上部（6）的吸入通道（16）具有用于分散粉末药物的单元（15），所述单元（15）连接到穿刺元件（11），其中上部（6） 可以相对于壳体的下部（1）移动壳体以便打开泡罩腔。
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公开(公告)号：US08919342B2
公开(公告)日：2014-12-30
申请号：US12671115
申请日：2008-07-31
CPC分类号： A61M15/0028 , A61M15/003 , A61M15/0033 , A61M2202/064 , A61M2206/16
摘要： In an inhaler for administering a powdery medicament in the form of an inhalable substance, substance formulation or mixture, a blister cavity to be opened by piercing elements (11) is mounted in the lower part (1) of a housing (2), which has an upper part (6), designed as mouthpiece and with an inhalation channel (16), and of the lower part (1), which has an air inlet opening (9). The inhalation channel (16) of the upper part (6) of the housing has a unit (15) for dispersing the powdery medicament, said unit (15) being connected to the piercing elements (11), wherein the upper part (6) of the housing can be moved relative to the lower part (1) of the housing in order to open the blister cavity.
摘要翻译： 在用于施用可吸入物质，物质制剂或混合物形式的粉末药物的吸入器中，通过刺穿元件（11）打开的泡罩腔被安装在壳体（2）的下部（1）中， 具有设计成接口并具有吸入通道（16）的上部部分（6）和具有进气口（9）的下部部分（1）。 壳体上部（6）的吸入通道（16）具有用于分散粉末药物的单元（15），所述单元（15）连接到穿刺元件（11），其中上部（6） 可以相对于壳体的下部（1）移动壳体以便打开泡罩腔。
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公开(公告)号：US20110094507A1
公开(公告)日：2011-04-28
申请号：US12864527
申请日：2008-12-29
IPC分类号： A61M11/00
CPC分类号： A61M15/0005 , A61M11/002 , A61M15/0008 , A61M15/0026 , A61M15/0045 , A61M15/0051 , A61M15/0055 , A61M15/0058 , A61M15/0085 , A61M15/009 , A61M2202/064 , A61M2206/16
摘要： A passive inhaler (1) for delivery of a powder-form inhalation formulation from a blister strip (2) with a plurality of blister pockets (3) is proposed. The inhaler comprises an impaction element (31) onto which the air stream can impact together with entrained inhalation formulation for better deagglomeration. Alternatively, the inhaler comprises an oscillating and/or vibrating device (35) for better de-agglomeration of the inhalation formulation. Alternatively or additionally, the inhaler comprises one or two mixing means for generating swirls, preferably with opposite rotation directions.
摘要翻译： 提出了一种用于从具有多个泡罩袋（3）的泡罩条（2）输送粉末形式的吸入制剂的被动吸入器（1）。 吸入器包括冲击元件（31），空气流可以与夹带的吸入制剂一起冲击到冲击元件（31）上以便更好的解聚。 或者，吸入器包括用于更好地去吸附吸入制剂的振荡和/或振动装置（35）。 或者或另外，吸入器包括用于产生涡流的一个或两个混合装置，优选地具有相反的旋转方向。
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公开(公告)号：US09604017B2
公开(公告)日：2017-03-28
申请号：US11560267
申请日：2006-11-15
申请人： Hubert Hoelz , Stefan Lustenberger , Torsten Kuehn , Herbert Wachtel , Rolf Kuhn
发明人： Hubert Hoelz , Stefan Lustenberger , Torsten Kuehn , Herbert Wachtel , Rolf Kuhn
IPC分类号： A61M15/00
CPC分类号： A61M15/0035 , A61M15/0026 , A61M15/0028 , A61M15/003 , A61M15/0033
摘要： The invention relates to a powder inhaler with at least one specially sharpened needle, to ensure the precise piercing or cutting open of capsules and hence the optimum delivery of powdered medicament compositions, medicament formulations or medicament mixtures, as well as ensuring that little effort is needed to perforate or cut open the capsule.
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公开(公告)号：US08944054B2
公开(公告)日：2015-02-03
申请号：US12296980
申请日：2007-04-13
申请人： Herbert Wachtel , Johannes Geser , Burkhard P. Metzger , Michael Spallek , Michael Krueger , Hubert Kunze , Achim Moser , Elmar Mock , Antonino Lanci , Andre Klopfenstein
发明人： Herbert Wachtel , Johannes Geser , Burkhard P. Metzger , Michael Spallek , Michael Krueger , Hubert Kunze , Achim Moser , Elmar Mock , Antonino Lanci , Andre Klopfenstein
IPC分类号： A61M15/00
CPC分类号： A61M15/0045 , A61M15/0003 , A61M15/003 , A61M15/0048 , A61M15/0051 , A61M2202/064
摘要： A medicine dispensation device, in particular a multi-dose powder inhalator, for the dispensing of individual doses of medicine that has a number of medicine chambers contained in a medicine magazine shaped like a continuous loop. The medicine chambers form groups in such a manner that a mouthpiece reaches the different groups by an essentially complete rotation of the medicine magazine. This enables several medicine chambers—typically one, two or three—to be situated between two successive intake positions, which allows for a high density of medicine chambers and thus creates an inhalation device, which can be handled comfortably even when containing a great number of individual doses.
摘要翻译： 用于分配单个剂量的药物的药物分配装置，特别是多剂量粉末吸入器，其具有包含在形状类似连续环的药物盒中的多个药物室。 药盒以这样的方式形成组，即通过药盒的基本上完全的旋转使得口部到达不同的组。 这使得几个药室（通常为一个，两个或三个）位于两个连续的进入位置之间，这允许高密度的药物腔室，并且因此产生吸入装置，其可以舒适地处理，即使当包含大量 个别剂量。
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公开(公告)号：US08763607B2
公开(公告)日：2014-07-01
申请号：US12863871
申请日：2009-01-23
申请人： Herbert Wachtel , Andree Jung
发明人： Herbert Wachtel , Andree Jung
IPC分类号： A61M15/00
CPC分类号： A61M15/0045 , A61M15/0026 , A61M15/0036 , A61M15/0041 , A61M15/0051 , A61M2202/064
摘要： An inhaler for delivery of a powder-form inhalation formulation from a blister strip with a plurality of blister pockets containing the inhalation formulation in doses. The inhaler comprises a metallic piercing member with two piercing elements extending parallel to each other and inclined to the lid of a blister pocket to be punctured. To operate the inhaler, an air stream of ambient air can be sucked or delivered in order to discharge the respective dose from an opened blister pocket and to deliver the dose with the ambient air as an aerosol cloud.
摘要翻译： 一种吸入器，用于从泡罩带输送粉末形式的吸入制剂，其中多个泡囊袋含有剂量的吸入制剂。 吸入器包括具有两个刺穿元件的金属刺穿构件，两个刺穿元件彼此平行地延伸并且倾斜于要被刺破的泡罩袋的盖。 为了操作吸入器，可以吸入或输送环境空气的空气流，以便从开放的泡罩口袋排放相应的剂量，并且以环境空气作为气溶胶云递送剂量。
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7.发明授权Medicaments magazine, and a device and method for opening it; multi-dose powder inhaler 有权药品杂志，以及打开它的装置和方法; 多剂量粉剂吸入器公开(公告)号：US08602024B2
公开(公告)日：2013-12-10
申请号：US12296984
申请日：2007-04-13
申请人： Herbert Wachtel , Johannes Geser , Burkhard Metzger , Michael Spallek , Michael Krueger , Herbert Kunze , Achim Moser , Elmar Mock , Antonino Lanci , Andre Klopfenstein
发明人： Herbert Wachtel , Johannes Geser , Burkhard Metzger , Michael Spallek , Michael Krueger , Herbert Kunze , Achim Moser , Elmar Mock , Antonino Lanci , Andre Klopfenstein
CPC分类号： A61M15/0045 , A61M15/0043 , A61M15/0051
摘要： The invention relates to a medicament magazine with a plurality of doses of medicament, wherein the magazine is formed from a single foil strip in which pouches (2) for holding a medicament are formed as depicted in exemplary FIG. 1. The foil strip comprises for transporting the strip openings (4) on at least one side for the engagement of transporting pins. The foil strip has a certain width in the region of the pouches, which is less than the width of the foil in other regions, and the openings are arranged in this broader part of the foil strip. The invention also relates to a method and a device for opening a medicament magazine of this kind, the device preferably being constructed as a segmented wheel.
摘要翻译： 本发明涉及一种具有多个剂量的药物的药物储存器，其中所述料盒由单个箔条形成，其中形成用于保持药物的袋（2），如图示例所示。 箔条包括用于在至少一个侧面上传送条形开口（4）用于输送销的接合。 箔条在袋的区域中具有一定的宽度，其小于其它区域中的箔的宽度，并且开口布置在箔条的更宽的部分中。 本发明还涉及一种用于打开这种药物盒的方法和装置，该装置优选构造为分段轮。
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8.发明授权公开(公告)号：US08561610B2
公开(公告)日：2013-10-22
申请号：US13482359
申请日：2012-05-29
申请人： Herbert Wachtel , Johannes Geser , Burkhard Metzger , Michael Spallek , Michael Krueger , Hubert Kunze , Achim Moser , Elmar Mock , Antonino Lanci , Andre Klopfenstein
发明人： Herbert Wachtel , Johannes Geser , Burkhard Metzger , Michael Spallek , Michael Krueger , Hubert Kunze , Achim Moser , Elmar Mock , Antonino Lanci , Andre Klopfenstein
CPC分类号： A61M15/0045 , A61M15/0003 , A61M15/002 , A61M15/0028 , A61M15/0035 , A61M15/0038 , A61M15/0043 , A61M15/0048 , A61M2202/064 , A61M2206/16
摘要： A medicament dispensing device, a medicament magazine thereof, and a method of removing a medicament from the medicament magazine. The inhaler has a mouthpiece (9) and an air channel (4) connected thereto, as well as a medicament magazine with at least one medicament chamber containing a powdered medicament. A drive current is produced in the air channel, while a vacuum flow (5′) can be produced by the drive current and a constriction formed in the air channel. This narrowest part of the air channel that produces the vacuum flow is connected to a removal opening (2) which communicates with a control opening (3), in order to form an emptying current through the control opening via the removal opening. In a preferred embodiment the at least one medicament chamber including the control opening, the removal opening and a fill opening are housing in the one-piece medicament magazine.
摘要翻译： 一种药物分配装置，其药物盒，以及从药物盒中去除药物的方法。 吸入器具有接口（9）和连接到其上的空气通道（4），以及具有至少一个含有粉末状药物的药物室的药剂盒。 在空气通道中产生驱动电流，而可以通过驱动电流和在空气通道中形成的收缩来产生真空流（5'）。 产生真空流的空气通道的最窄部分连接到与控制开口（3）连通的去除开口（2），以便通过去除开口形成通过控制开口的排空电流。 在优选实施例中，包括控制开口，去除开口和填充开口的至少一个药剂室容纳在一体式药剂盒中。
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公开(公告)号：US20130269685A1
公开(公告)日：2013-10-17
申请号：US13703998
申请日：2011-06-01
申请人： Herbert Wachtel , Andree Jung
发明人： Herbert Wachtel , Andree Jung
CPC分类号： A61M15/0091 , A61M11/02 , A61M15/0065 , A61M15/008 , A61M15/0083 , A61M2016/0021 , A61M2016/0027 , A61M2205/332 , A61M2205/3553 , A61M2205/8293 , B05B11/0037 , B05B11/0038 , B05B11/00412 , B05B11/00446 , B05B11/308 , B05B11/3091 , B05B12/008 , B05B12/02 , B05B12/12
摘要： An inhaler is proposed having an insertable container and a monitoring device for counting uses of the inhaler. The monitoring device is arranged in a detachable housing part or fitted onto a mouthpiece of the inhaler. A supply air current is detected by means of a pressure sensor. A position sensor may further be provided.
摘要翻译： 建议吸入器具有可插入的容器和用于计数吸入器的使用的监测装置。 监视装置布置在可拆卸的壳体部分中或装配到吸入器的接口上。 通过压力传感器检测供应气流。 还可以设置位置传感器。
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公开(公告)号：US08281784B2
公开(公告)日：2012-10-09
申请号：US12296783
申请日：2007-04-04
申请人： Herbert Wachtel
发明人： Herbert Wachtel
IPC分类号： A61M15/00
CPC分类号： A61M15/0028 , A61M15/0021 , A61M15/0026 , A61M2206/14
摘要： A mouthpiece for an inhaler for administering a drug in the form of substances, substance formulations or substance mixtures that can be inhaled comprises an inhalation channel (4) for coupling to a chamber for receiving the drug. At least one component (10) having an aerodynamic cross-section is arranged in the inhalation channel (4).
摘要翻译： 用于施用药物形式的吸入器的接口管，其可以被吸入的物质，物质制剂或物质混合物的形式包括用于连接到用于接收药物的室的吸入通道（4）。 具有空气动力学横截面的至少一个部件（10）布置在吸入通道（4）中。
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